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UBERON:0003073

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Name:lens placode
Definition:"A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." [Wikipedia:Lens_placode, ZFIN:curator]
Xrefs:
links:

AAO:0011055
EFO:0003494
EHDAA:2908
EHDAA2:0000982
EMAPA:16672
ncithesaurus:Lens_Placodes
TAO:0000122
VHOG:0000166
XAO:0000240

ZFA:0000122
Comments:Classical transplantation experiments using amphibian embryos suggested that the optic vesicle is the source of lens-inducing signals sufficient to generate lens tissues in competent ectoderm (reviewed in Grainger et al., 1996). More recent findings suggest a multistep model for lens induction. There is now good evidence that lens specification occurs at the neurula stage, before the optic vesicle contact the surface ectoderm, and that neural crest cell migration in the frontonasal region is required to restrict the position of the lens placode (Bailey et al., 2006)[NBK53175]
Alt_id: UBERON:XAO_0000240-ZFA_0000122
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002546(cranial placode)
part_of:UBERON:0000076(external ectoderm)



Children

develops from:UBERON:0000965 (lens of camera-type eye),UBERON:0005426 (lens vesicle)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003073 (lens placode), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.41e-88FFCP PHASE1:Hg19::chr22:25595823..25595826,+#_1210ba7537b0a9ddbd04e6defaace213p1@CRYBB3
1.41e-88FFCP PHASE2:Hg19::chr22:25595823..25595826,+#_1210ba7537b0a9ddbd04e6defaace213p1@CRYBB3
3.32e-74FFCP PHASE2:Hg19::chr22:25615600..25615611,+#_1ecb723c4dd9f07483dad4408d0640c0p1@CRYBB2
3.32e-74FFCP PHASE1:Hg19::chr22:25615600..25615611,+#_1ecb723c4dd9f07483dad4408d0640c0p1@CRYBB2
5.48e-74FFCP PHASE2:Hg19::chr19:51891222..51891233,-#_3b3315cbe7bfb4f628f6d5f0beac1681p1@LIM2
5.48e-74FFCP PHASE1:Hg19::chr19:51891222..51891233,-#_3b3315cbe7bfb4f628f6d5f0beac1681p1@LIM2
3.8e-56FFCP PHASE2:Hg19::chr22:27017921..27017928,+#_1eb6cbf2e00021636f407d8e934fcf64p1@CRYBA4
3.8e-56FFCP PHASE1:Hg19::chr22:27017921..27017928,+#_1eb6cbf2e00021636f407d8e934fcf64p1@CRYBA4
3.1e-50FFCP PHASE2:Hg19::chr13:104778247..104778293,+#_5e3d4c844706d4e1d3ef97b733a305f2p@chr13:104778247..104778293, +
3.1e-50FFCP PHASE1:Hg19::chr13:104778247..104778293,+#_5e3d4c844706d4e1d3ef97b733a305f2p@chr13:104778247..104778293, +
3.1e-50FFCP PHASE2:Hg19::chr20:61204240..61204241,+#_5e3d4c844706d4e1d3ef97b733a305f2p@chr20:61204240..61204241, +
3.1e-50FFCP PHASE1:Hg19::chr20:61204240..61204241,+#_5e3d4c844706d4e1d3ef97b733a305f2p@chr20:61204240..61204241, +
5.14e-50FFCP PHASE1:Hg19::chr21:44592820..44592840,-#_c51b472fdd8a1b85496e9ff7bbe90700p2@CU686889
5.14e-50FFCP PHASE2:Hg19::chr14:37642016..37642022,-#_c51b472fdd8a1b85496e9ff7bbe90700p7@SLC25A21
5.14e-50FFCP PHASE1:Hg19::chr14:37642016..37642022,-#_c51b472fdd8a1b85496e9ff7bbe90700p7@SLC25A21
5.14e-50FFCP PHASE2:Hg19::chr21:44592820..44592840,-#_c51b472fdd8a1b85496e9ff7bbe90700p2@CU686889
6.6e-50FFCP PHASE2:Hg19::chr12:132475501..132475504,+#_2b900d55a03bed2391ada198693b9e63p@chr12:132475501..132475504, +
6.6e-50FFCP PHASE2:Hg19::chr21:44589339..44589372,-#_2b900d55a03bed2391ada198693b9e63p@chr21:44589339..44589372, -
6.6e-50FFCP PHASE1:Hg19::chr12:132475501..132475504,+#_2b900d55a03bed2391ada198693b9e63p@chr12:132475501..132475504, +
6.6e-50FFCP PHASE1:Hg19::chr21:44592842..44592867,-#_2b900d55a03bed2391ada198693b9e63p1@CU686889
6.6e-50FFCP PHASE1:Hg19::chr21:44589339..44589372,-#_2b900d55a03bed2391ada198693b9e63p@chr21:44589339..44589372, -
6.6e-50FFCP PHASE2:Hg19::chr21:44592842..44592867,-#_2b900d55a03bed2391ada198693b9e63p1@CU686889
6.27e-44FFCP PHASE1:Hg19::chr11:31827535..31827565,-#_c3893329f233e61fb399aefee197b5c6p11@PAX6
6.27e-44FFCP PHASE2:Hg19::chr11:31827535..31827565,-#_c3893329f233e61fb399aefee197b5c6p11@PAX6
1.92e-41FFCP PHASE1:Hg19::chr3:186262166..186262170,-#_b08f70fe5f20e9bd500eb415622aa614p1@CRYGS
1.92e-41FFCP PHASE2:Hg19::chr3:186262166..186262170,-#_b08f70fe5f20e9bd500eb415622aa614p1@CRYGS
4.94e-40FFCP PHASE1:Hg19::chr5:112173525..112173532,+#_b294001efb5f0930a84d0bdcf7919ffcp@chr5:112173525..112173532, +
4.94e-40FFCP PHASE2:Hg19::chr5:112173525..112173532,+#_b294001efb5f0930a84d0bdcf7919ffcp@chr5:112173525..112173532, +
1.62e-37FFCP PHASE1:Hg19::chr1:29586692..29586705,+#_184e0d8f28920daf18c496133e0f9141p7@PTPRU
1.62e-37FFCP PHASE2:Hg19::chr1:29586692..29586705,+#_184e0d8f28920daf18c496133e0f9141p7@PTPRU
2.1e-35FFCP PHASE2:Hg19::chr14:60975644..60975673,+#_042c8aeab2b95d0ab48adff70eb37352p3@SIX6
2.1e-35FFCP PHASE1:Hg19::chr14:60975644..60975673,+#_042c8aeab2b95d0ab48adff70eb37352p3@SIX6
6.73e-35FFCP PHASE2:Hg19::chr14:60975871..60975880,+#_c2d02a6d2ed366da62facbc73354c1e8p4@SIX6
6.73e-35FFCP PHASE1:Hg19::chr14:60975871..60975880,+#_c2d02a6d2ed366da62facbc73354c1e8p4@SIX6
5.06e-34FFCP PHASE2:Hg19::chr11:31667372..31667383,-#_9ae2067beba8f51ee156c4e1a3267952p@chr11:31667372..31667383, -
5.06e-34FFCP PHASE1:Hg19::chr11:31667372..31667383,-#_9ae2067beba8f51ee156c4e1a3267952p@chr11:31667372..31667383, -
8.36e-34FFCP PHASE1:Hg19::chr19:1470631..1470648,-#_12b4754692e85e1fa5fabce4bf7ee015p@chr19:1470631..1470648, -
8.36e-34FFCP PHASE2:Hg19::chr19:1470631..1470648,-#_12b4754692e85e1fa5fabce4bf7ee015p@chr19:1470631..1470648, -
5.55e-33FFCP PHASE1:Hg19::chr21:44589135..44589151,+#_b7c4c420f740dd8e4fa54fe572a705e8p1@CRYAA
5.55e-33FFCP PHASE2:Hg19::chr21:44589135..44589151,+#_b7c4c420f740dd8e4fa54fe572a705e8p1@CRYAA
9.55e-33FFCP PHASE1:Hg19::chr17:27573875..27573878,+#_2fd7c377a3d75c5450e9294b7bda726fp1@CRYBA1
9.55e-33FFCP PHASE2:Hg19::chr17:27573875..27573878,+#_2fd7c377a3d75c5450e9294b7bda726fp1@CRYBA1
2.74e-29FFCP PHASE2:Hg19::chr2:45168589..45168601,-#_e354c73c00362b493a5c51bb823d24a8p2@ENST00000456467
2.74e-29FFCP PHASE1:Hg19::chr2:45168589..45168601,-#_e354c73c00362b493a5c51bb823d24a8p2@ENST00000456467
3.65e-29FFCP PHASE2:Hg19::chr7:107883678..107883689,-#_6042122c156f2cea0e18aec1bfee19fbp13@NRCAM
3.65e-29FFCP PHASE1:Hg19::chr7:107883678..107883689,-#_6042122c156f2cea0e18aec1bfee19fbp13@NRCAM
7.46e-29FFCP PHASE2:Hg19::chr13:114202163..114202178,+#_98bf3b4c7616b2327ea403fdfb9e0c3cp@chr13:114202163..114202178, +
7.46e-29FFCP PHASE1:Hg19::chr13:114202163..114202178,+#_98bf3b4c7616b2327ea403fdfb9e0c3cp@chr13:114202163..114202178, +
1.36e-28FFCP PHASE1:Hg19::chr3:173116225..173116242,+#_5df463a49aff9bc8574d957f7d79ddb2p10@NLGN1
1.36e-28FFCP PHASE2:Hg19::chr3:173116225..173116242,+#_5df463a49aff9bc8574d957f7d79ddb2p10@NLGN1
2.64e-27FFCP PHASE2:Hg19::chr2:45169233..45169244,+#_fb3c83fad2de8aa80b16d70ae71a1aadp10@SIX3
2.64e-27FFCP PHASE1:Hg19::chr2:45169233..45169244,+#_fb3c83fad2de8aa80b16d70ae71a1aadp10@SIX3
8.39e-27FFCP PHASE2:Hg19::chr14:60975858..60975869,+#_b0aed23562ca46313d56eb5b050976a7p2@SIX6
8.39e-27FFCP PHASE1:Hg19::chr14:60975858..60975869,+#_b0aed23562ca46313d56eb5b050976a7p2@SIX6
5.56e-26FFCP PHASE2:Hg19::chr1:147374915..147374932,+#_b8084f8bd7d0ab2dcca57659dbfa8447p1@GJA8
5.56e-26FFCP PHASE1:Hg19::chr3:150690809..150690822,-#_b8084f8bd7d0ab2dcca57659dbfa8447p3@CLRN1
5.56e-26FFCP PHASE2:Hg19::chr20:35861148..35861151,+#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr20:35861148..35861151, +
5.56e-26FFCP PHASE1:Hg19::chrX:43587410..43587413,+#_b8084f8bd7d0ab2dcca57659dbfa8447p@chrX:43587410..43587413, +
5.56e-26FFCP PHASE2:Hg19::chr9:75848662..75848671,-#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr9:75848662..75848671, -
5.56e-26FFCP PHASE1:Hg19::chr1:147374915..147374932,+#_b8084f8bd7d0ab2dcca57659dbfa8447p1@GJA8
5.56e-26FFCP PHASE2:Hg19::chr19:40920692..40920700,-#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr19:40920692..40920700, -
5.56e-26FFCP PHASE1:Hg19::chr20:35861148..35861151,+#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr20:35861148..35861151, +
5.56e-26FFCP PHASE2:Hg19::chr3:150690809..150690822,-#_b8084f8bd7d0ab2dcca57659dbfa8447p3@CLRN1
5.56e-26FFCP PHASE1:Hg19::chr9:75848662..75848671,-#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr9:75848662..75848671, -
5.56e-26FFCP PHASE2:Hg19::chrX:43587410..43587413,+#_b8084f8bd7d0ab2dcca57659dbfa8447p@chrX:43587410..43587413, +
5.56e-26FFCP PHASE1:Hg19::chr19:40920692..40920700,-#_b8084f8bd7d0ab2dcca57659dbfa8447p@chr19:40920692..40920700, -
7.14e-26FFCP PHASE2:Hg19::chr3:156322310..156322314,-#_dcfab7a626c48003c70e8e8abbfed385p@chr3:156322310..156322314, -
7.14e-26FFCP PHASE1:Hg19::chr5:45038620..45038622,+#_dcfab7a626c48003c70e8e8abbfed385p@chr5:45038620..45038622, +
7.14e-26FFCP PHASE2:Hg19::chr19:41727698..41727705,+#_dcfab7a626c48003c70e8e8abbfed385p@chr19:41727698..41727705, +
7.14e-26FFCP PHASE2:Hg19::chr7:123198284..123198329,-#_dcfab7a626c48003c70e8e8abbfed385p3@NDUFA5
7.14e-26FFCP PHASE2:Hg19::chr21:44592626..44592635,-#_dcfab7a626c48003c70e8e8abbfed385p5@CU686889
7.14e-26FFCP PHASE2:Hg19::chr16:17563573..17563582,+#_dcfab7a626c48003c70e8e8abbfed385p@chr16:17563573..17563582, +
7.14e-26FFCP PHASE1:Hg19::chr2:693025..693036,+#_dcfab7a626c48003c70e8e8abbfed385p@chr2:693025..693036, +
7.14e-26FFCP PHASE1:Hg19::chr16:17563573..17563582,+#_dcfab7a626c48003c70e8e8abbfed385p@chr16:17563573..17563582, +
7.14e-26FFCP PHASE1:Hg19::chr11:65361417..65361421,-#_dcfab7a626c48003c70e8e8abbfed385p2@KCNK7
7.14e-26FFCP PHASE1:Hg19::chr8:94870047..94870056,+#_dcfab7a626c48003c70e8e8abbfed385p30@PDP1
7.14e-26FFCP PHASE2:Hg19::chr19:17137781..17137792,-#_dcfab7a626c48003c70e8e8abbfed385p6@CPAMD8
7.14e-26FFCP PHASE2:Hg19::chr9:100057272..100057276,+#_dcfab7a626c48003c70e8e8abbfed385p@chr9:100057272..100057276, +
7.14e-26FFCP PHASE1:Hg19::chr16:85617064..85617073,-#_dcfab7a626c48003c70e8e8abbfed385p@chr16:85617064..85617073, -
7.14e-26FFCP PHASE1:Hg19::chr5:464155..464205,+#_dcfab7a626c48003c70e8e8abbfed385p@chr5:464155..464205, +
7.14e-26FFCP PHASE1:Hg19::chr21:44592512..44592521,+#_dcfab7a626c48003c70e8e8abbfed385p@chr21:44592512..44592521, +
7.14e-26FFCP PHASE2:Hg19::chr21:44592750..44592758,-#_dcfab7a626c48003c70e8e8abbfed385p4@CU686889
7.14e-26FFCP PHASE2:Hg19::chr4:140656282..140656285,-#_dcfab7a626c48003c70e8e8abbfed385p@chr4:140656282..140656285, -
7.14e-26FFCP PHASE1:Hg19::chr21:36253916..36253918,-#_dcfab7a626c48003c70e8e8abbfed385p@chr21:36253916..36253918, -
7.14e-26FFCP PHASE2:Hg19::chr1:45769711..45769721,-#_dcfab7a626c48003c70e8e8abbfed385p@chr1:45769711..45769721, -
7.14e-26FFCP PHASE2:Hg19::chr13:72440726..72440736,-#_dcfab7a626c48003c70e8e8abbfed385p19@DACH1
7.14e-26FFCP PHASE1:Hg19::chr19:41727698..41727705,+#_dcfab7a626c48003c70e8e8abbfed385p@chr19:41727698..41727705, +
7.14e-26FFCP PHASE1:Hg19::chr13:72440726..72440736,-#_dcfab7a626c48003c70e8e8abbfed385p19@DACH1
7.14e-26FFCP PHASE2:Hg19::chr20:33903184..33903189,-#_dcfab7a626c48003c70e8e8abbfed385p11@UQCC
7.14e-26FFCP PHASE2:Hg19::chr21:44592358..44592365,+#_dcfab7a626c48003c70e8e8abbfed385p@chr21:44592358..44592365, +
7.14e-26FFCP PHASE2:Hg19::chr10:73406056..73406065,+#_dcfab7a626c48003c70e8e8abbfed385p@chr10:73406056..73406065, +
7.14e-26FFCP PHASE2:Hg19::chr2:45154282..45154288,-#_dcfab7a626c48003c70e8e8abbfed385p@chr2:45154282..45154288, -
7.14e-26FFCP PHASE1:Hg19::chr3:156322310..156322314,-#_dcfab7a626c48003c70e8e8abbfed385p@chr3:156322310..156322314, -
7.14e-26FFCP PHASE1:Hg19::chr7:123198284..123198329,-#_dcfab7a626c48003c70e8e8abbfed385p3@NDUFA5
7.14e-26FFCP PHASE1:Hg19::chr21:44592626..44592635,-#_dcfab7a626c48003c70e8e8abbfed385p5@CU686889
7.14e-26FFCP PHASE2:Hg19::chr21:44592788..44592807,+#_dcfab7a626c48003c70e8e8abbfed385p@chr21:44592788..44592807, +
7.14e-26FFCP PHASE1:Hg19::chr19:17137781..17137792,-#_dcfab7a626c48003c70e8e8abbfed385p6@CPAMD8
7.14e-26FFCP PHASE1:Hg19::chr9:100057272..100057276,+#_dcfab7a626c48003c70e8e8abbfed385p@chr9:100057272..100057276, +
7.14e-26FFCP PHASE2:Hg19::chr1:86064794..86064797,+#_dcfab7a626c48003c70e8e8abbfed385p1@ENST00000426794
7.14e-26FFCP PHASE2:Hg19::chr1:115873480..115873484,+#_dcfab7a626c48003c70e8e8abbfed385p@chr1:115873480..115873484, +

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