CL:0000049

Name:	common myeloid progenitor
Namespace:	FANTOM
Definition:	"A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata-1, Gata2, C/EBPa, and Pu.1." [GOC:add, GOC:dsd, GOC:tfm, ISBN:0878932437, MESH:D023461, PMCID:PMC2212039, PMID:10724173, PMID:16551251]
Synonyms:	"cfu-gemm" RELATED [ISBN:0878932437] "CFU-S" RELATED [ISBN:0878932437] "CMP" EXACT [ISBN:0878932437] "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437] "common myeloid precursor" EXACT [] "multipotential myeloid stem cell" RELATED [ISBN:0878932437] "myeloid stem cell" RELATED [ISBN:0878932437] "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437]
Comments:	CMP are reportedly CD38-positive, CD45RA-negative, and CD123-positive.

Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	CL:0002032(hematopoietic oligopotent progenitor cell)
disjoint_from:	CL:0000050(megakaryocyte-erythroid progenitor cell),CL:0000051(common lymphoid progenitor),CL:0000557(granulocyte monocyte progenitor cell)

Children

derives from:	FF:0000041 (common myeloid progenitor sample)
develops from:	CL:0000050 (megakaryocyte-erythroid progenitor cell),CL:0000557 (granulocyte monocyte progenitor cell),CL:0000763 (myeloid cell),CL:0000766 (myeloid leukocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

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Human (Homo sapiens)

• 12122-128C7 (common myeloid progenitor CMP, biol_rep1)
• 12125-128D1 (common myeloid progenitor CMP, biol_rep2)
• 12128-128D4 (common myeloid progenitor CMP, biol_rep3)
• 12130-128D6 (common myeloid progenitor CMP, donor1)
• 12134-128E1 (common myeloid progenitor CMP, donor2)
• 12138-128E5

Mouse (Mus musculus)

• 12122-128C7 (common myeloid progenitor CMP, biol_rep1)
• 12125-128D1 (common myeloid progenitor CMP, biol_rep2)
• 12128-128D4 (common myeloid progenitor CMP, biol_rep3)
• 12130-128D6 (common myeloid progenitor CMP, donor1)
• 12134-128E1 (common myeloid progenitor CMP, donor2)
• 12138-128E5

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000049 (common myeloid progenitor), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
5.01e-115	FFCP PHASE2:Hg19::chr11:47399920..47399931,-	p7@SPI1
5.01e-115	FFCP PHASE1:Hg19::chr11:47399920..47399931,-	p7@SPI1
6.88e-112	FFCP PHASE2:Hg19::chr11:47400045..47400060,-	p6@SPI1
6.88e-112	FFCP PHASE1:Hg19::chr11:47400045..47400060,-	p6@SPI1
1.87e-103	FFCP PHASE2:Hg19::chr8:55074639..55074655,+	p@chr8:55074639..55074655, +
1.87e-103	FFCP PHASE1:Hg19::chr8:55074639..55074655,+	p@chr8:55074639..55074655, +
5.28e-102	FFCP PHASE2:Hg19::chr2:109204876..109204889,+	p7@LIMS1
5.28e-102	FFCP PHASE1:Hg19::chr2:109204876..109204889,+	p7@LIMS1
3.01e-101	FFCP PHASE1:Hg19::chr19:54876689..54876707,-	p6@LAIR1
3.01e-101	FFCP PHASE2:Hg19::chr19:54876689..54876707,-	p6@LAIR1
2.92e-100	FFCP PHASE2:Hg19::chr17:72528538..72528554,+	p@chr17:72528538..72528554, +
2.92e-100	FFCP PHASE1:Hg19::chr17:72528538..72528554,+	p@chr17:72528538..72528554, +
1.71e-99	FFCP PHASE2:Hg19::chr11:47400032..47400043,-	p5@SPI1
1.71e-99	FFCP PHASE1:Hg19::chr11:47400032..47400043,-	p5@SPI1
3.09e-99	FFCP PHASE2:Hg19::chr6:137105174..137105195,+	p@chr6:137105174..137105195, +
3.09e-99	FFCP PHASE1:Hg19::chr6:137105174..137105195,+	p@chr6:137105174..137105195, +
3.6e-99	FFCP PHASE1:Hg19::chr19:55084438..55084495,+	p2@LILRA2
3.6e-99	FFCP PHASE2:Hg19::chr19:55084438..55084495,+	p2@LILRA2
5.23e-99	FFCP PHASE1:Hg19::chr12:118796868..118796885,-	p6@TAOK3
5.23e-99	FFCP PHASE2:Hg19::chr12:118796868..118796885,-	p6@TAOK3
2.14e-98	FFCP PHASE1:Hg19::chr18:2847062..2847071,+	p7@EMILIN2
2.14e-98	FFCP PHASE2:Hg19::chr18:2847062..2847071,+	p7@EMILIN2
2.31e-97	FFCP PHASE2:Hg19::chr15:65174546..65174583,-	p@chr15:65174546..65174583, -
2.31e-97	FFCP PHASE1:Hg19::chr15:65174546..65174583,-	p@chr15:65174546..65174583, -
4.87e-97	FFCP PHASE2:Hg19::chr20:35202667..35202682,+	p4@C20orf24
4.87e-97	FFCP PHASE1:Hg19::chr20:35202667..35202682,+	p4@C20orf24
1.04e-96	FFCP PHASE1:Hg19::chr13:108922429..108922446,+	p6@TNFSF13B
1.04e-96	FFCP PHASE2:Hg19::chr13:108922429..108922446,+	p6@TNFSF13B
1.68e-96	FFCP PHASE1:Hg19::chr11:47399947..47399961,-	p3@SPI1
1.68e-96	FFCP PHASE2:Hg19::chr11:47399947..47399961,-	p3@SPI1
3.76e-96	FFCP PHASE2:Hg19::chr17:72709134..72709145,-	p2@CD300LF
3.76e-96	FFCP PHASE1:Hg19::chr17:72709134..72709145,-	p2@CD300LF
6.69e-96	FFCP PHASE1:Hg19::chr19:36400209..36400286,-	p@chr19:36400209..36400286, -
6.69e-96	FFCP PHASE2:Hg19::chr19:36400209..36400286,-	p@chr19:36400209..36400286, -
7.75e-96	FFCP PHASE1:Hg19::chr11:70161074..70161080,-	p@chr11:70161074..70161080, -
7.75e-96	FFCP PHASE2:Hg19::chr11:70161074..70161080,-	p@chr11:70161074..70161080, -
7.57e-95	FFCP PHASE1:Hg19::chr2:109204909..109204928,+	p3@LIMS1
7.57e-95	FFCP PHASE2:Hg19::chr2:109204909..109204928,+	p3@LIMS1
1.23e-94	FFCP PHASE1:Hg19::chr6:36665587..36665612,+	p1@uc010jwl.1
1.23e-94	FFCP PHASE2:Hg19::chr6:36665587..36665612,+	p1@uc010jwl.1
4.83e-94	FFCP PHASE2:Hg19::chr22:46998103..46998127,-	p@chr22:46998103..46998127, -
4.83e-94	FFCP PHASE1:Hg19::chr22:46998103..46998127,-	p@chr22:46998103..46998127, -
6.81e-94	FFCP PHASE1:Hg19::chr5:57787254..57787271,+	p2@GAPT
6.81e-94	FFCP PHASE2:Hg19::chr5:57787254..57787271,+	p2@GAPT
2.22e-93	FFCP PHASE1:Hg19::chr6:31583632..31583651,+	p5@AIF1
2.22e-93	FFCP PHASE2:Hg19::chr6:31583632..31583651,+	p5@AIF1
6.0e-93	FFCP PHASE2:Hg19::chr16:50313426..50313459,+	p@chr16:50313426..50313459, +
6.0e-93	FFCP PHASE1:Hg19::chr16:50313426..50313459,+	p@chr16:50313426..50313459, +
7.03e-93	FFCP PHASE2:Hg19::chr11:47399996..47400014,-	p4@SPI1
7.03e-93	FFCP PHASE1:Hg19::chr11:47399996..47400014,-	p4@SPI1
9.92e-93	FFCP PHASE2:Hg19::chr17:4642716..4642727,-	p7@CXCL16
9.92e-93	FFCP PHASE1:Hg19::chr17:4642716..4642727,-	p7@CXCL16
1.41e-92	FFCP PHASE1:Hg19::chr3:98482159..98482172,+	p5@ST3GAL6
1.41e-92	FFCP PHASE2:Hg19::chr3:98482159..98482172,+	p5@ST3GAL6
1.63e-92	FFCP PHASE1:Hg19::chr6:137105206..137105220,+	p@chr6:137105206..137105220, +
1.63e-92	FFCP PHASE2:Hg19::chr6:137105206..137105220,+	p@chr6:137105206..137105220, +
2.56e-92	FFCP PHASE1:Hg19::chr13:108922478..108922493,+	p5@TNFSF13B
2.56e-92	FFCP PHASE2:Hg19::chr13:108922478..108922493,+	p5@TNFSF13B
6.37e-92	FFCP PHASE1:Hg19::chr22:37257098..37257115,+	p3@NCF4
6.37e-92	FFCP PHASE2:Hg19::chr22:37257098..37257115,+	p3@NCF4
7.64e-92	FFCP PHASE2:Hg19::chr19:36398154..36398173,-	p@chr19:36398154..36398173, -
7.64e-92	FFCP PHASE1:Hg19::chr19:36398154..36398173,-	p@chr19:36398154..36398173, -
1.22e-91	FFCP PHASE2:Hg19::chr7:2832730..2832791,+	p@chr7:2832730..2832791, +
1.22e-91	FFCP PHASE1:Hg19::chr7:2832730..2832791,+	p@chr7:2832730..2832791, +
2.01e-91	FFCP PHASE1:Hg19::chr17:9923211..9923249,-	p10@GAS7
2.01e-91	FFCP PHASE2:Hg19::chr17:9923211..9923249,-	p10@GAS7
4.57e-91	FFCP PHASE2:Hg19::chr5:176936817..176936841,-	p2@DOK3
4.57e-91	FFCP PHASE1:Hg19::chr5:176936817..176936841,-	p2@DOK3
1.8e-90	FFCP PHASE2:Hg19::chr22:37257002..37257013,+	p4@NCF4
1.8e-90	FFCP PHASE1:Hg19::chr22:37257002..37257013,+	p4@NCF4
2.43e-90	FFCP PHASE1:Hg19::chr19:18286116..18286156,+	p@chr19:18286116..18286156, +
2.43e-90	FFCP PHASE2:Hg19::chr19:18286116..18286156,+	p@chr19:18286116..18286156, +
3.13e-90	FFCP PHASE1:Hg19::chr1:161188661..161188679,+	p@chr1:161188661..161188679, +
3.13e-90	FFCP PHASE2:Hg19::chr1:161188661..161188679,+	p@chr1:161188661..161188679, +
9.35e-90	FFCP PHASE2:Hg19::chr6:31554766..31554777,+	p8@LST1
9.35e-90	FFCP PHASE1:Hg19::chr6:31554766..31554777,+	p8@LST1
9.81e-90	FFCP PHASE2:Hg19::chr17:6916789..6916808,+	p10@C17orf49
9.81e-90	FFCP PHASE1:Hg19::chr17:6916789..6916808,+	p10@C17orf49
1.04e-89	FFCP PHASE1:Hg19::chr14:103587759..103587770,+	p@chr14:103587759..103587770, +
1.04e-89	FFCP PHASE2:Hg19::chr14:103587759..103587770,+	p@chr14:103587759..103587770, +
2.62e-89	FFCP PHASE2:Hg19::chr19:51714319..51714374,+	p@chr19:51714319..51714374, +
2.62e-89	FFCP PHASE1:Hg19::chr19:51714319..51714374,+	p@chr19:51714319..51714374, +
4.84e-89	FFCP PHASE1:Hg19::chr6:137105237..137105263,+	p@chr6:137105237..137105263, +
4.84e-89	FFCP PHASE2:Hg19::chr6:137105237..137105263,+	p@chr6:137105237..137105263, +
4.9e-89	FFCP PHASE2:Hg19::chr5:176936844..176936870,-	p3@DOK3
4.9e-89	FFCP PHASE1:Hg19::chr5:176936844..176936870,-	p3@DOK3
7.3e-89	FFCP PHASE2:Hg19::chr22:32034409..32034470,-	p4@PISD
7.3e-89	FFCP PHASE1:Hg19::chr22:32034409..32034470,-	p4@PISD
8.29e-89	FFCP PHASE2:Hg19::chr1:161039459..161039478,-	p4@ARHGAP30
8.29e-89	FFCP PHASE1:Hg19::chr1:161039459..161039478,-	p4@ARHGAP30
9.58e-89	FFCP PHASE2:Hg19::chr1:161475228..161475239,+	p3@FCGR2A
9.58e-89	FFCP PHASE1:Hg19::chr1:161475228..161475239,+	p3@FCGR2A
1.26e-88	FFCP PHASE2:Hg19::chr18:5466317..5466374,-	p@chr18:5466317..5466374, -
1.26e-88	FFCP PHASE1:Hg19::chr18:5466317..5466374,-	p@chr18:5466317..5466374, -
1.34e-88	FFCP PHASE1:Hg19::chr16:8738211..8738249,+	p@chr16:8738211..8738249, +
1.34e-88	FFCP PHASE2:Hg19::chr16:8738211..8738249,+	p@chr16:8738211..8738249, +
2.3e-88	FFCP PHASE1:Hg19::chr19:18285955..18285972,+	p@chr19:18285955..18285972, +
2.3e-88	FFCP PHASE2:Hg19::chr19:18285955..18285972,+	p@chr19:18285955..18285972, +
3.13e-88	FFCP PHASE2:Hg19::chr1:28211791..28211853,+	p@chr1:28211791..28211853, +
3.13e-88	FFCP PHASE1:Hg19::chr1:28211791..28211853,+	p@chr1:28211791..28211853, +

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