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Coexpression cluster:C337

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Full id: C337_ovary_testis_Adipocyte_mesothelioma_chorionic_placenta_spleen



Phase1 CAGE Peaks

Hg19::chr11:126297301..126297307,+p@chr11:126297301..126297307
+
Hg19::chr11:32449555..32449601,-p@chr11:32449555..32449601
-
Hg19::chr11:77282391..77282402,+p@chr11:77282391..77282402
+
Hg19::chr12:53817633..53817654,+p2@AMHR2
Hg19::chr14:24162052..24162064,+p@chr14:24162052..24162064
+
Hg19::chr14:24162221..24162248,+p@chr14:24162221..24162248
+
Hg19::chr15:95869470..95869478,+p@chr15:95869470..95869478
+
Hg19::chr15:95869480..95869493,+p@chr15:95869480..95869493
+
Hg19::chr17:42154416..42154417,-p12@HDAC5
Hg19::chr17:48912744..48912756,+p6@WFIKKN2
Hg19::chr17:48912862..48912869,+p13@WFIKKN2
Hg19::chr17:48913152..48913158,+p9@WFIKKN2
Hg19::chr19:14223852..14223882,-p7@PRKACA
Hg19::chr19:35800769..35800809,+p@chr19:35800769..35800809
+
Hg19::chr19:35800815..35800836,+p@chr19:35800815..35800836
+
Hg19::chr19:7197281..7197297,+p@chr19:7197281..7197297
+
Hg19::chr1:110993754..110993788,+p1@PROK1
Hg19::chr1:110993795..110993824,+p2@PROK1
Hg19::chr1:111970353..111970358,-p2@OVGP1
Hg19::chr1:205326089..205326108,-p7@KLHDC8A
Hg19::chr1:205326161..205326172,-p12@KLHDC8A
Hg19::chr1:205342383..205342394,+p1@LOC284576
Hg19::chr1:38411522..38411549,-p10@INPP5B
Hg19::chr20:32850613..32850632,+p@chr20:32850613..32850632
+
Hg19::chr2:11696330..11696373,+p23@GREB1
Hg19::chr2:11696464..11696478,+p12@GREB1
Hg19::chr2:11696495..11696507,+p16@GREB1
Hg19::chr2:11696574..11696586,+p17@GREB1
Hg19::chr3:151257198..151257223,-p@chr3:151257198..151257223
-
Hg19::chr3:151257224..151257250,-p@chr3:151257224..151257250
-
Hg19::chr3:15374659..15374696,-p10@SH3BP5
Hg19::chr5:79946291..79946314,-p@chr5:79946291..79946314
-
Hg19::chr6:151314557..151314569,+p@chr6:151314557..151314569
+
Hg19::chr8:38002524..38002528,-p@chr8:38002524..38002528
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001880Mullerian duct regression0.049487045737182
GO:0060033anatomical structure regression0.049487045737182
GO:0004439phosphoinositide 5-phosphatase activity0.049487045737182
GO:0005071transmembrane receptor protein serine/threonine kinase signaling protein activity0.049487045737182
GO:0004445inositol-polyphosphate 5-phosphatase activity0.049487045737182
GO:0046030inositol trisphosphate phosphatase activity0.049487045737182
GO:0004691cAMP-dependent protein kinase activity0.049487045737182
GO:0045843negative regulation of striated muscle development0.049487045737182
GO:0022414reproductive process0.049487045737182
GO:0004690cyclic nucleotide-dependent protein kinase activity0.049487045737182
GO:0042577lipid phosphatase activity0.049487045737182
GO:0016202regulation of striated muscle development0.049487045737182
GO:0016566specific transcriptional repressor activity0.049487045737182
GO:0006032chitin catabolic process0.049487045737182
GO:0006046N-acetylglucosamine catabolic process0.049487045737182
GO:0006043glucosamine catabolic process0.049487045737182
GO:0046348amino sugar catabolic process0.049487045737182
GO:0006030chitin metabolic process0.049487045737182
GO:0004568chitinase activity0.049487045737182



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
testis1.57e-178
gonad5.66e-1521
indifferent external genitalia5.66e-1521
indifferent gonad5.66e-1521
gonad primordium5.66e-1521
external genitalia2.49e-1422
male reproductive organ4.80e-1311
spleen3.24e-123
gastrointestinal system mesentery3.24e-123
stomach region3.24e-123
mesentery3.24e-123
gastrointestinal system serosa3.24e-123
mesentery of stomach3.24e-123
gut mesentery3.24e-123
dorsal mesentery3.24e-123
dorsal mesogastrium3.24e-123
peritoneal cavity3.24e-123
spleen primordium3.24e-123
body cavity4.51e-1246
reproductive organ1.32e-1148
body cavity or lining2.28e-1149
body cavity precursor2.28e-1054
reproductive structure1.52e-0959
reproductive system1.52e-0959
anatomical cavity3.07e-0961
male organism5.24e-0722
male reproductive system5.24e-0722
uterine cervix8.97e-076
neck of organ8.97e-076


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.000156531
MA0004.10.0757747
MA0006.10.246818
MA0007.10.240088
MA0009.10.375925
MA0014.13.3258e-05
MA0017.10.904952
MA0019.10.462016
MA0024.10.294311
MA0025.11.22181
MA0027.11.90579
MA0028.10.027018
MA0029.10.308904
MA0030.10.300221
MA0031.11.30051
MA0038.10.792032
MA0040.10.313366
MA0041.10.285156
MA0042.10.900203
MA0043.10.376179
MA0046.10.367181
MA0048.10.164128
MA0050.12.46472
MA0051.13.21544
MA0052.10.316327
MA0055.10.135086
MA0056.10
MA0057.10.385569
MA0058.10.0404315
MA0059.10.156159
MA0060.10.00534716
MA0061.10.144596
MA0063.10
MA0066.10.793058
MA0067.10.649823
MA0068.10.088417
MA0069.10.364099
MA0070.10.355189
MA0071.10.7003
MA0072.10.351626
MA0073.10.187008
MA0074.10.123313
MA0076.10.173334
MA0077.10.345539
MA0078.10.537126
MA0081.10.156318
MA0083.10.381987
MA0084.10.823032
MA0087.10.349692
MA0088.10.162232
MA0089.10
MA0090.10.188379
MA0091.10.265508
MA0092.10.481008
MA0093.10.0239335
MA0095.10
MA0098.10
MA0100.10.416655
MA0101.10.105302
MA0103.10.0930326
MA0105.10.0089638
MA0106.10.14939
MA0107.10.0542121
MA0108.20.69888
MA0109.10
MA0111.10.202948
MA0113.10.159148
MA0114.10.490887
MA0115.10.581155
MA0116.10.151824
MA0117.10.406527
MA0119.10.936418
MA0122.10.42795
MA0124.10.544476
MA0125.10.471774
MA0130.10
MA0131.10.193896
MA0132.10
MA0133.10
MA0135.10.400588
MA0136.10.129893
MA0139.10.0163043
MA0140.10.340312
MA0141.12.43129
MA0142.10.230443
MA0143.10.159255
MA0144.11.70505
MA0145.10.00369633
MA0146.10.0196608
MA0147.10.058287
MA0148.11.52127
MA0149.10.0995233
MA0062.20.0589056
MA0035.20.339371
MA0039.20.000329659
MA0138.20.183007
MA0002.20.171397
MA0137.21.21469
MA0104.20.0294015
MA0047.21.39109
MA0112.20.551029
MA0065.21.04098
MA0150.10.0483839
MA0151.10
MA0152.11.7133
MA0153.10.457467
MA0154.10.199178
MA0155.10.504569
MA0156.10.533005
MA0157.11.79066
MA0158.10
MA0159.11.51568
MA0160.11.58899
MA0161.10
MA0162.10.00239879
MA0163.10.0964265
MA0164.10.499229
MA0080.20.473679
MA0018.20.45833
MA0099.20.107829
MA0079.20.000750601
MA0102.20.858102
MA0258.11.62364
MA0259.10.0634142
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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