DOID:1793

Name:	pancreatic cancer
Namespace:	FANTOM
Definition:	"An endocrine gland cancer located_in the pancreas." [url:http://en.wikipedia.org/wiki/Pancreatic]
Xrefs:	Expandlinks: MSH:D010190 NCI:C3305 SNOMEDCT_2010_1_31:126859007 SNOMEDCT_2010_1_31:154476001 SNOMEDCT_2010_1_31:154477005 SNOMEDCT_2010_1_31:154478000 SNOMEDCT_2010_1_31:187791002 SNOMEDCT_2010_1_31:187792009 SNOMEDCT_2010_1_31:187796007 SNOMEDCT_2010_1_31:269553001 SNOMEDCT_2010_1_31:269554007 SNOMEDCT_2010_1_31:269555008 SNOMEDCT_2010_1_31:363419009 SNOMEDCT_2010_1_31:93715005 SNOMEDCT_2010_1_31:93823001 SNOMEDCT_2010_1_31:94082003 UMLS_CUI:C0030297 UMLS_CUI:C0153458 UMLS_CUI:C0153459 UMLS_CUI:C0153460 UMLS_CUI:C0153463
Synonyms:	"Ca body of pancreas" EXACT [SNOMEDCT_2005_07_31:154477005] "Ca body of pancreas (disorder)" EXACT [SNOMEDCT_2005_07_31:269554007] "Ca head of pancreas" EXACT [SNOMEDCT_2005_07_31:154476001] "Ca tail of pancreas" EXACT [SNOMEDCT_2005_07_31:154478000] "Ca tail of pancreas (disorder)" EXACT [SNOMEDCT_2005_07_31:269555008] "malignant neoplasm of body of pancreas" EXACT [] "malignant neoplasm of head of pancreas" EXACT [] "malignant neoplasm of tail of pancreas" EXACT [] "malignant tumor of body of pancreas (disorder)" EXACT [SNOMEDCT_2005_07_31:187791002] "malignant tumor of tail of pancreas (disorder)" EXACT [SNOMEDCT_2005_07_31:187792009] "neoplasm of pancreas (disorder)" EXACT [SNOMEDCT_2005_07_31:126859007] "pancreas neoplasm" EXACT [CSP2005:2014-4876] "pancreatic neoplasm" EXACT [MTH:NOCODE] "pancreatic tumor" EXACT [NCI2004_11_17:C3305]
Alt_id:	DOID:14356 DOID:1797 DOID:3588 DOID:9859

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	DOID:170(endocrine gland cancer)

Children

is a:	DOID:1799 (islet cell tumor),DOID:4905 (pancreatic carcinoma)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

• 10438-106E6 (ductal cell carcinoma cell line:KLM-1)
• 10488-107B2 (ductal cell carcinoma cell line:MIA Paca2)
• 10489-107B3
• 10515-107E2
• 10531-107F9
• 10542-107H2
• 10543-107H3
• 10698-109G5 (pancreatic carcinoma cell line:NOR-P1)
• 10797-110I5 (tubular adenocarcinoma cell line:SUIT-2)

Mouse (Mus musculus)

• 10438-106E6 (ductal cell carcinoma cell line:KLM-1)
• 10488-107B2 (ductal cell carcinoma cell line:MIA Paca2)
• 10489-107B3
• 10515-107E2
• 10531-107F9
• 10542-107H2
• 10543-107H3
• 10698-109G5 (pancreatic carcinoma cell line:NOR-P1)
• 10797-110I5 (tubular adenocarcinoma cell line:SUIT-2)

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:1793 (pancreatic cancer), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
4.67e-66	FFCP PHASE1:Hg19::chr16:57945799..57945809,-	p@chr16:57945799..57945809, -
4.67e-66	FFCP PHASE2:Hg19::chr16:57945799..57945809,-	p@chr16:57945799..57945809, -
3.1e-50	FFCP PHASE2:Hg19::chr3:189028187..189028196,+	p@chr3:189028187..189028196, +
3.1e-50	FFCP PHASE1:Hg19::chr2:196278365..196278367,+	p@chr2:196278365..196278367, +
3.1e-50	FFCP PHASE1:Hg19::chr5:57529719..57529726,+	p@chr5:57529719..57529726, +
3.1e-50	FFCP PHASE1:Hg19::chr7:45928212..45928215,+	p14@IGFBP1
3.1e-50	FFCP PHASE1:Hg19::chr5:27707697..27707707,+	p@chr5:27707697..27707707, +
3.1e-50	FFCP PHASE2:Hg19::chr2:196278365..196278367,+	p@chr2:196278365..196278367, +
3.1e-50	FFCP PHASE2:Hg19::chr5:57529719..57529726,+	p@chr5:57529719..57529726, +
3.1e-50	FFCP PHASE2:Hg19::chr7:45928212..45928215,+	p14@IGFBP1
3.1e-50	FFCP PHASE2:Hg19::chr5:27707697..27707707,+	p@chr5:27707697..27707707, +
3.1e-50	FFCP PHASE2:Hg19::chr11:65144695..65144697,-	p@chr11:65144695..65144697, -
3.1e-50	FFCP PHASE1:Hg19::chr4:81224883..81224888,+	p@chr4:81224883..81224888, +
3.1e-50	FFCP PHASE1:Hg19::chr2:139791292..139791303,+	p@chr2:139791292..139791303, +
3.1e-50	FFCP PHASE1:Hg19::chr2:114004420..114004422,-	p@chr2:114004420..114004422, -
3.1e-50	FFCP PHASE2:Hg19::chr16:1128952..1128957,+	p4@SSTR5
3.1e-50	FFCP PHASE1:Hg19::chr11:65144695..65144697,-	p@chr11:65144695..65144697, -
3.1e-50	FFCP PHASE2:Hg19::chr2:139791292..139791303,+	p@chr2:139791292..139791303, +
3.1e-50	FFCP PHASE1:Hg19::chr16:1128952..1128957,+	p4@SSTR5
3.1e-50	FFCP PHASE2:Hg19::chr4:81224883..81224888,+	p@chr4:81224883..81224888, +
3.1e-50	FFCP PHASE2:Hg19::chr2:114004420..114004422,-	p@chr2:114004420..114004422, -
3.1e-50	FFCP PHASE1:Hg19::chr1:163063326..163063330,+	p@chr1:163063326..163063330, +
3.1e-50	FFCP PHASE2:Hg19::chr1:163063326..163063330,+	p@chr1:163063326..163063330, +
3.1e-50	FFCP PHASE2:Hg19::chr11:13895146..13895156,+	p@chr11:13895146..13895156, +
3.1e-50	FFCP PHASE1:Hg19::chr1:98779728..98779733,-	p@chr1:98779728..98779733, -
3.1e-50	FFCP PHASE1:Hg19::chr1:162724324..162724330,+	p@chr1:162724324..162724330, +
3.1e-50	FFCP PHASE2:Hg19::chr16:1129001..1129004,+	p6@SSTR5
3.1e-50	FFCP PHASE1:Hg19::chr1:78001338..78001348,+	p@chr1:78001338..78001348, +
3.1e-50	FFCP PHASE1:Hg19::chr16:1129001..1129004,+	p6@SSTR5
3.1e-50	FFCP PHASE1:Hg19::chr11:13895146..13895156,+	p@chr11:13895146..13895156, +
3.1e-50	FFCP PHASE1:Hg19::chr3:83659759..83659783,-	p@chr3:83659759..83659783, -
3.1e-50	FFCP PHASE2:Hg19::chr1:98779728..98779733,-	p@chr1:98779728..98779733, -
3.1e-50	FFCP PHASE1:Hg19::chr2:139757287..139757309,+	p@chr2:139757287..139757309, +
3.1e-50	FFCP PHASE2:Hg19::chr1:162724324..162724330,+	p@chr1:162724324..162724330, +
3.1e-50	FFCP PHASE2:Hg19::chr1:78001338..78001348,+	p@chr1:78001338..78001348, +
3.1e-50	FFCP PHASE1:Hg19::chr2:113425862..113425864,+	p@chr2:113425862..113425864, +
3.1e-50	FFCP PHASE1:Hg19::chr3:189151408..189151415,+	p@chr3:189151408..189151415, +
3.1e-50	FFCP PHASE2:Hg19::chr3:83659759..83659783,-	p@chr3:83659759..83659783, -
3.1e-50	FFCP PHASE1:Hg19::chr5:57529651..57529657,+	p@chr5:57529651..57529657, +
3.1e-50	FFCP PHASE2:Hg19::chr2:139757287..139757309,+	p@chr2:139757287..139757309, +
3.1e-50	FFCP PHASE1:Hg19::chr18:2409216..2409225,-	p@chr18:2409216..2409225, -
3.1e-50	FFCP PHASE1:Hg19::chr6:165990105..165990115,-	p10@PDE10A
3.1e-50	FFCP PHASE1:Hg19::chr8:41052616..41052617,-	p@chr8:41052616..41052617, -
3.1e-50	FFCP PHASE1:Hg19::chr2:126468524..126468553,+	p3@ENST00000430692
3.1e-50	FFCP PHASE2:Hg19::chr12:79954988..79954992,-	p@chr12:79954988..79954992, -
3.1e-50	FFCP PHASE1:Hg19::chr1:98850479..98850511,-	p@chr1:98850479..98850511, -
3.1e-50	FFCP PHASE2:Hg19::chr2:113425862..113425864,+	p@chr2:113425862..113425864, +
3.1e-50	FFCP PHASE2:Hg19::chr3:189151408..189151415,+	p@chr3:189151408..189151415, +
3.1e-50	FFCP PHASE2:Hg19::chr5:57529651..57529657,+	p@chr5:57529651..57529657, +
3.1e-50	FFCP PHASE1:Hg19::chr9:38059452..38059455,-	p@chr9:38059452..38059455, -
3.1e-50	FFCP PHASE1:Hg19::chr20:58533857..58533867,-	p@chr20:58533857..58533867, -
3.1e-50	FFCP PHASE2:Hg19::chr6:165990105..165990115,-	p10@PDE10A
3.1e-50	FFCP PHASE2:Hg19::chr18:2409216..2409225,-	p@chr18:2409216..2409225, -
3.1e-50	FFCP PHASE2:Hg19::chr8:41052616..41052617,-	p@chr8:41052616..41052617, -
3.1e-50	FFCP PHASE2:Hg19::chr2:126468524..126468553,+	p3@ENST00000430692
3.1e-50	FFCP PHASE1:Hg19::chr12:79954988..79954992,-	p@chr12:79954988..79954992, -
3.1e-50	FFCP PHASE2:Hg19::chr1:98850479..98850511,-	p@chr1:98850479..98850511, -
3.1e-50	FFCP PHASE1:Hg19::chr2:139791188..139791193,+	p@chr2:139791188..139791193, +
3.1e-50	FFCP PHASE2:Hg19::chr10:114885416..114885423,+	p@chr10:114885416..114885423, +
3.1e-50	FFCP PHASE2:Hg19::chr9:38059452..38059455,-	p@chr9:38059452..38059455, -
3.1e-50	FFCP PHASE2:Hg19::chr20:58533857..58533867,-	p@chr20:58533857..58533867, -
3.1e-50	FFCP PHASE1:Hg19::chr2:109605568..109605573,-	p6@EDAR
3.1e-50	FFCP PHASE1:Hg19::chr2:196278203..196278206,+	p@chr2:196278203..196278206, +
3.1e-50	FFCP PHASE1:Hg19::chr5:57529696..57529706,+	p@chr5:57529696..57529706, +
3.1e-50	FFCP PHASE2:Hg19::chr2:139791188..139791193,+	p@chr2:139791188..139791193, +
3.1e-50	FFCP PHASE1:Hg19::chr20:42980646..42980651,+	p@chr20:42980646..42980651, +
3.1e-50	FFCP PHASE1:Hg19::chr6:165990158..165990169,-	p12@PDE10A
3.1e-50	FFCP PHASE1:Hg19::chr10:114885416..114885423,+	p@chr10:114885416..114885423, +
3.1e-50	FFCP PHASE2:Hg19::chr2:196278203..196278206,+	p@chr2:196278203..196278206, +
3.1e-50	FFCP PHASE2:Hg19::chr5:57529696..57529706,+	p@chr5:57529696..57529706, +
3.1e-50	FFCP PHASE2:Hg19::chr2:109605568..109605573,-	p6@EDAR
3.1e-50	FFCP PHASE2:Hg19::chr20:42980646..42980651,+	p@chr20:42980646..42980651, +
3.1e-50	FFCP PHASE1:Hg19::chr3:189028187..189028196,+	p@chr3:189028187..189028196, +
3.1e-50	FFCP PHASE2:Hg19::chr6:165990158..165990169,-	p12@PDE10A
4.94e-40	FFCP PHASE1:Hg19::chr20:42780550..42780563,+	p@chr20:42780550..42780563, +
4.94e-40	FFCP PHASE2:Hg19::chr20:42780550..42780563,+	p@chr20:42780550..42780563, +
9.88e-34	FFCP PHASE2:Hg19::chr3:133174860..133174888,-	p1@ENST00000515542, p1@uc003epo.2
9.88e-34	FFCP PHASE1:Hg19::chr2:71277301..71277315,+	p@chr2:71277301..71277315, +
9.88e-34	FFCP PHASE1:Hg19::chr3:133174860..133174888,-	p1@ENST00000515542, p1@uc003epo.2
9.88e-34	FFCP PHASE2:Hg19::chr2:71277301..71277315,+	p@chr2:71277301..71277315, +
5.56e-26	FFCP PHASE1:Hg19::chr2:139791209..139791219,+	p@chr2:139791209..139791219, +
5.56e-26	FFCP PHASE1:Hg19::chr11:119056147..119056152,+	p3@PDZD3
5.56e-26	FFCP PHASE2:Hg19::chr20:58533868..58533877,-	p@chr20:58533868..58533877, -
5.56e-26	FFCP PHASE2:Hg19::chr3:138103078..138103094,+	p@chr3:138103078..138103094, +
5.56e-26	FFCP PHASE2:Hg19::chr4:93623257..93623261,+	p@chr4:93623257..93623261, +
5.56e-26	FFCP PHASE2:Hg19::chr2:139791209..139791219,+	p@chr2:139791209..139791219, +
5.56e-26	FFCP PHASE2:Hg19::chr12:71771004..71771010,+	p@chr12:71771004..71771010, +
5.56e-26	FFCP PHASE1:Hg19::chr19:54274746..54274752,+	p@chr19:54274746..54274752, +
5.56e-26	FFCP PHASE2:Hg19::chr13:63967430..63967434,+	p@chr13:63967430..63967434, +
5.56e-26	FFCP PHASE1:Hg19::chr12:71771004..71771010,+	p@chr12:71771004..71771010, +
5.56e-26	FFCP PHASE1:Hg19::chr21:36216696..36216726,-	p@chr21:36216696..36216726, -
5.56e-26	FFCP PHASE1:Hg19::chr19:15162579..15162588,+	p5@CASP14
5.56e-26	FFCP PHASE2:Hg19::chr19:54274746..54274752,+	p@chr19:54274746..54274752, +
5.56e-26	FFCP PHASE1:Hg19::chr13:63967430..63967434,+	p@chr13:63967430..63967434, +
5.56e-26	FFCP PHASE2:Hg19::chr11:2314912..2314928,-	p@chr11:2314912..2314928, -
5.56e-26	FFCP PHASE1:Hg19::chr6:169691363..169691375,-	p@chr6:169691363..169691375, -
5.56e-26	FFCP PHASE2:Hg19::chr21:36216696..36216726,-	p@chr21:36216696..36216726, -
5.56e-26	FFCP PHASE1:Hg19::chr9:78949005..78949024,-	p@chr9:78949005..78949024, -
5.56e-26	FFCP PHASE2:Hg19::chr19:15162579..15162588,+	p5@CASP14
5.56e-26	FFCP PHASE1:Hg19::chr19:10311868..10311875,-	p@chr19:10311868..10311875, -

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