EntrezGene:26410

Symbol:	Map3k8
Description:	mitogen-activated protein kinase kinase kinase 8
Synonyms:	Cot, Cot/Tpl2, Est, Estf, Tpl-2, Tpl2, c-COT
Species:	Mouse (Mus musculus)
Xrefs:	ExpandEntrezGene:26410 MGI:1346878 Ensembl:ENSMUSG00000024235 Vega:OTTMUSG00000037645
Associated motifs:	NA
Transcripton Factor?:	No

TSS regions

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Mm9::chr18:4336287..4336296,-	p8@Map3k8
Mm9::chr18:4352914..4352921,-	p5@Map3k8
Mm9::chr18:4352942..4352960,-	p1@Map3k8
Mm9::chr18:4353224..4353236,-	p9@Map3k8
Mm9::chr18:4353243..4353254,-	p3@Map3k8
Mm9::chr18:4353280..4353328,-	p2@Map3k8
Mm9::chr18:4353333..4353350,-	p10@Map3k8
Mm9::chr18:4353410..4353429,-	p11@Map3k8
TSS peak ID	Short_description

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TSS expression

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Sample	p1@Map3k8	p2@Map3k8	p3@Map3k8	p5@Map3k8

Sample	p1@Map3k8	p2@Map3k8	p3@Map3k8	p5@Map3k8
CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J).CNhs13219.11816-124E7	65.33	60.82	3.38	0.99
CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl).CNhs13226.11820-124F2	57.11	50.56	4.21	3.04
accessory axillary lymph node, adult.CNhs10475.1063-29H9	48.94	7.25	0.78	1.55
macrophage, bone marrow derived, pool2.CNhs11532.3632-171A1	48.41	1.63	1.63	0.54
MC1+Gr1+ myeloid-derived suppressor cells control, donor2 (0127 PBS).CNhs12541.12162-128H2	42.35	0.68	0.68	1.37
macrophage, bone marrow derived, pool1.CNhs11457.3560-170A1	39.21	1.51	0.00	0.00
MC1+Gr1+ myeloid-derived suppressor cells cancer, donor3 (0128 3LL).CNhs12542.12163-128H3	36.12	0.00	0.00	3.14
EBF KO HPCs induced to T cell, 00hr00min, biol_rep1.CNhs11058.12972-138H2	34.26	3.57	1.79	2.48
MC1+Gr1+ myeloid-derived suppressor cells cancer, donor2 (0127 3LL).CNhs12198.12161-128H1	32.03	2.34	0.78	1.56
Mouse CD19+ B Cells, donor1.CNhs13531.11856-125A2	31.71	4.87	1.01	2.01
Mouse hepatic Sinusoidal Endothelial Cells, donor1.CNhs13209.11830-124G3	30.44	20.58	4.35	11.01
CD41+ megakaryocyte control, donor2.CNhs13214.11777-124A4	29.62	3.43	1.23	0.82
EBF KO HPCs induced to T cell, 00hr00min, biol_rep2.CNhs12980.12988-138I9	28.99	1.83	1.04	3.66
MC1+Gr1+ myeloid-derived suppressor cells control, donor1 (4,5,6PBS).CNhs12540.12160-128G9	28.82	1.76	0.59	0.59
MC1+Gr1+ myeloid-derived suppressor cells cancer, donor1 (10,11,12 3LL).CNhs12539.12159-128G8	28.04	0.84	0.42	1.26
MC1+Gr1+ myeloid-derived suppressor cells control, donor3 (0128 PBS).CNhs12543.12164-128H4	27.19	0.49	0.49	0.49
CD41+ megakaryocyte control, donor3.CNhs13201.11779-124A6	27.16	2.55	0.00	1.27
CD41+ megakaryocyte control, donor1.CNhs13212.11775-124A2	26.97	3.94	0.63	1.42
Mouse Cardiac Myocytes, donor2.CNhs12356.11729-123E1	15.19	0.86	0.00	0.57
Mouse Mesenchymal stem cells - bone marrow derived, donor2.CNhs12633.11735-123E7	14.83	1.98	0.00	0.00
CD4+CD25+ regulatory T cells, pool2 (Balb_cAJcl).CNhs13221.11818-124E9	14.07	6.84	0.65	0.52
vagina, adult.CNhs10502.89-27D5	13.93	0.43	0.00	2.36
skin, neonate N00.CNhs11124.650-25G4	13.72	0.81	0.16	0.32
amnion, adult pregnant day17.5.CNhs10488.583-22A8	13.60	1.24	0.74	1.24
skin, neonate N06.CNhs11097.693-20I5	13.13	0.48	0.60	0.48
submandibular gland, adult.CNhs10469.59-29C1	13.05	1.86	0.00	0.00
Mouse Astrocytes - hippocampus, donor2.CNhs12077.11551-120C3	13.03	0.00	0.00	0.58
lung, adult.CNhs10474.28-22B1	12.93	3.33	1.85	1.11
Mouse Mesenchymal stem cells - bone marrow derived, donor3.CNhs12616.11640-122D2	12.79	2.13	1.42	0.00
stem cell (cKit+ Sca1- lineage-) KSL, biol_rep2.CNhs12535.12124-128C9	12.74	23.79	3.78	1.12
placenta, adult pregnant day10.CNhs10472.539-13I7	12.67	0.23	0.70	0.47
Mouse Cardiac Myocytes, donor3.CNhs12353.11634-122C5	12.38	2.06	0.00	0.52
skin, adult.CNhs10492.30-1C3	12.20	0.82	0.66	0.66
skin, neonate N10.CNhs11108.762-6C4	11.82	0.49	0.16	0.49
lung, neonate N20.CNhs11109.822-18A4	11.80	3.44	0.66	0.16
forelimb, embryo E18.CNhs11008.1520-43B5	11.52	1.23	0.41	0.41
spleen, adult.CNhs10465.25-2G2	11.45	1.37	0.68	0.17
uterus, adult pregnant day19.CNhs10497.590-15F5	11.26	1.31	0.19	0.94
stem cell (cKit+ Sca1- lineage-) KSL, biol_rep1.CNhs12534.12121-128C6	11.22	19.89	1.70	1.36
CD41+ megakaryocyte cancer, donor1.CNhs13079.11774-124A1	10.99	0.67	0.33	0.33
lung, neonate N30.CNhs11133.1394-42H2	10.99	3.91	1.59	0.43
Mouse Mesenchymal stem cells - bone marrow derived, donor1.CNhs12628.11717-123C7	10.80	1.80	2.25	1.35
spleen, neonate N25.CNhs11099.1354-25G3	10.75	1.60	0.92	0.00
stem cell (cKit+ Sca1- lineage-) KSL, biol_rep3.CNhs12536.12127-128D3	10.50	17.97	2.90	0.55
skin, neonate N03.CNhs11215.662-22H3	9.53	0.48	0.06	0.24
tongue, adult.CNhs10499.32-1B4	9.07	0.68	0.23	0.45
Mouse Meningeal cells, donor3.CNhs12109.11639-122D1	8.89	0.00	0.00	0.00
spleen, neonate N20.CNhs11112.824-19H1	8.89	1.78	0.00	0.14
lung, neonate N25.CNhs11119.1359-25C7	8.63	3.45	0.00	0.52
stomach, neonate N25.CNhs11104.1355-25E4	8.38	0.00	0.26	0.52
forelimb, embryo E17.CNhs10598.1517-43C4	8.36	1.04	0.00	0.35
Mouse Astrocytes - hippocampus, donor1.CNhs12129.11709-123B8	8.35	0.44	0.00	0.00
trophoblast stem cell line R1AB differentiation, day00, biol_rep1.CNhs13481.13283-142F7	7.89	0.00	0.27	0.27
Mouse Aortic Smooth Muscle cells - differentiated, biol_rep2.CNhs11056.11485-119D9	7.81	1.22	0.20	0.41
stomach, neonate N07.CNhs11210.718-18A9	7.27	0.33	0.41	0.33
common myeloid progenitor CMP, biol_rep2.CNhs12203.12125-128D1	7.20	10.20	0.60	0.00
bone (os femoris), adult.CNhs10483.56-12G2	7.08	0.00	0.88	0.00
Mouse Aortic Smooth Muscle cells - differentiated, biol_rep1.CNhs11055.11484-119D8	6.92	1.26	0.25	0.25
trophoblast stem cell line Rybp differentiation, day00, biol_rep1.CNhs13519.13290-142G5	6.88	0.17	0.00	0.34
common myeloid progenitor CMP, biol_rep1.CNhs12550.12122-128C7	6.83	14.14	3.00	0.36
aorta, adult.CNhs10498.46-23H1	6.80	0.87	0.43	0.29
Mouse Astrocytes - cerebellar, donor2.CNhs12076.11550-120C2	6.76	0.22	0.00	0.00
intestine, embryo E17.CNhs10582.482-18D3	6.67	0.44	0.00	0.00
Mouse CD4+ T Cells, donor1.CNhs13509.11854-124I9	6.53	2.90	0.73	0.00
epididymis and seminiferous tubule, neonate N30.CNhs11199.1387-42A2	6.47	1.24	0.12	0.00
lung, embryo E18.CNhs10583.1287-20I6	6.43	1.67	0.48	0.24
common myeloid progenitor CMP, biol_rep3.CNhs12551.12128-128D4	6.35	6.10	1.14	0.51
granulocyte macrophage progenitor GMP, biol_rep1.CNhs12206.12123-128C8	6.32	2.11	0.70	0.00
Mouse Cardiac Myocytes, donor1.CNhs12355.11711-123C1	6.17	0.26	0.77	0.26
CD41+ megakaryocyte cancer, donor2.CNhs13213.11776-124A3	6.07	0.81	0.40	0.61
intestine, neonate N10.CNhs11098.755-23A5	6.04	0.39	0.00	0.00
lung, neonate N06.CNhs11212.683-20E5	5.99	1.58	0.47	0.32
trophoblast stem cell line B1 differentiation, day00, biol_rep1.CNhs13526.13297-142H3	5.99	0.22	0.00	0.44
intestine, neonate N07.CNhs11095.720-20F2	5.97	0.60	0.20	0.40
placenta, adult pregnant day17.CNhs10464.577-18G3	5.93	0.21	0.64	0.00
Mouse CD8+ T Cells, donor1.CNhs13511.11855-125A1	5.71	2.69	0.67	0.00
Mouse Aortic Smooth Muscle cells, donor1.CNhs11297.11299-117B3	5.69	0.18	0.00	0.18
stomach, embryo E17.CNhs11006.1035-18D5	5.65	0.21	0.00	0.42
lung, neonate N07.CNhs11111.715-19A3	5.54	3.10	0.00	0.00
lung, neonate N00.CNhs11224.640-42C6	5.46	3.51	0.59	0.00
lung, neonate N10.CNhs11219.750-23E6	5.42	2.39	0.16	0.00
whole body, embryo E18.CNhs10516.493-3B3	5.38	0.70	0.47	0.23
stomach, embryo E18.CNhs10999.1286-20C6	5.24	0.66	0.00	0.22
liver, neonate N07.CNhs11103.716-20H2	5.21	2.60	0.00	0.37
whole body, neonate N00.CNhs10525.657-19C2	5.16	0.43	0.00	0.21
liver, adult pregnant day01.CNhs10466.508-5B2	5.04	0.30	0.59	0.00
heart, embryo E11.CNhs10586.331-24E9	4.97	0.41	0.00	1.04
intestine, embryo E18.CNhs10526.1289-20F7	4.95	0.19	0.00	0.57
oviduct, adult pregnant day01.CNhs10500.988-6G6	4.95	0.99	0.82	0.16
spleen, neonate N10.CNhs11116.752-24D1	4.90	0.57	0.00	0.19
eyeball, adult.CNhs10484.31-12G4	4.84	0.21	0.21	0.21
urinary bladder, adult.CNhs10481.879-12E4	4.83	0.19	0.39	0.00
Mouse Microglia, donor1.CNhs12629.11718-123C8	4.79	0.30	1.20	0.30
Mouse hepatocyte, donor1.CNhs13078.11714-123C4	4.76	0.00	0.00	0.00
CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J).CNhs13218.11815-124E6	4.62	6.34	0.34	0.00
whole body, neonate N01.CNhs10576.659-23C6	4.59	1.15	0.19	0.38
mammary gland, adult lactating day02.CNhs10480.595-22B6	4.43	0.00	0.98	0.00
thymus, adult.CNhs10471.38-12B5	4.42	2.53	0.00	0.00
heart, neonate N20.CNhs11127.821-26I6	4.39	1.90	0.15	0.00
lung, embryo E17.CNhs10605.480-44A6	4.36	0.67	0.00	0.17
liver, neonate N30.CNhs11106.1382-42D1	4.34	0.48	0.00	0.00
liver, neonate N06.CNhs11101.684-20A8	4.31	2.88	0.00	0.00
granulocyte macrophage progenitor GMP, biol_rep3.CNhs11928.12129-128D5	4.26	2.56	1.14	0.57
heart, embryo E14.CNhs10597.403-26D4	4.26	0.24	0.00	0.24
whole body, embryo E17.CNhs10517.475-3I5	4.25	0.50	0.00	0.00
pancreas, neonate N25.CNhs11094.1555-45E2	4.22	0.00	0.00	0.00
thymus, neonate N30.CNhs11132.1393-42G2	4.21	1.75	0.12	0.12
bone (os femoris), neonate N16.CNhs11225.1525-43A6	4.20	0.22	0.00	0.22
stomach, neonate N03.CNhs11193.1340-24B8	4.18	0.40	0.13	0.40
ovary, adult.CNhs10507.91-2I7	4.12	0.57	0.14	0.14
whole body, embryo E17.5, pool1 (internal control).CNhs11246.3139-67G5	4.09	0.41	0.00	0.00
spleen, embryo E18.CNhs11011.1271-21F2	4.07	0.56	0.37	0.56
liver, neonate N10.CNhs11115.751-24B9	4.06	1.25	0.31	0.00
uterus, adult.CNhs10509.92-27E5	4.03	0.37	0.18	0.00
adrenal gland, adult.CNhs10508.49-24D7	4.01	0.74	0.30	0.15
pancreas, neonate N01.CNhs11138.1531-43D7	4.00	0.00	0.00	0.36
intestine, neonate N01.CNhs11192.1322-23E9	3.95	0.16	0.16	0.00
Mouse Astrocytes - cerebellar, donor1.CNhs13077.11708-123B7	3.91	0.00	0.78	0.78
thymus, neonate N25.CNhs11125.1362-25G7	3.85	1.44	0.00	0.10
Mouse Microglia, donor2.CNhs12634.11736-123E8	3.84	0.38	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10591.3139-67G5	3.80	0.25	0.25	0.25
Mouse Astrocytes, donor2.CNhs12078.11552-120C4	3.78	0.28	0.14	0.00
CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J).CNhs13217.11813-124E4	3.77	1.71	0.17	0.00
cerebellum, neonate N30.CNhs11135.1395-42I2	3.77	0.42	0.63	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10607.3139-67G5	3.77	0.00	0.38	0.19
cecum, adult.CNhs10467.37-13H4	3.73	0.00	0.00	0.00
spleen, embryo E16.CNhs11035.461-43C1	3.71	0.00	0.21	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11120.3139-67G5	3.68	0.00	0.00	0.26
intestine, embryo E16.CNhs10585.463-22H4	3.63	0.00	0.00	0.00
mammary gland, adult pregnant day19.CNhs10476.588-5H2	3.59	0.28	0.28	0.28
thymus, embryo E15.CNhs11005.430-45I2	3.59	0.41	0.10	0.21
Tracheal epithelial cells, differentiation to ciliated epithelial cells, 000hr, biol_rep3.CNhs13741.13369-143G3	3.54	0.00	0.00	1.01
liver, neonate N20.CNhs11220.823-25A3	3.54	0.25	0.25	0.00
muscle (biceps femoris), neonate N30.CNhs11129.1389-42C2	3.53	0.76	0.00	0.25
whole body, neonate N10.CNhs10518.761-6B4	3.48	0.93	0.46	0.23
whole body, embryo E17.5.CNhs10513.490-9F9	3.47	0.19	0.00	0.19
Mouse hepatic Stellate Cells (lipocyte), donor1.CNhs13196.11825-124F7	3.44	1.72	0.86	0.86
whole body, embryo E17.5, pool1 (internal control).CNhs11278.3139-67G5	3.41	0.46	0.00	0.00
Mouse Neurons - substantia nigra, donor5.CNhs12614.11490-119E5	3.38	1.13	0.00	0.00
kidney, embryo E16.CNhs10584.464-22A5	3.38	0.00	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11024.3139-67G5	3.37	0.00	0.18	0.00
granulocyte macrophage progenitor GMP, biol_rep2.CNhs12202.12126-128D2	3.35	3.35	0.77	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10725.3139-67G5	3.33	0.00	0.00	0.95
Mouse Neurons - raphe, donor1.CNhs12631.11722-123D3	3.30	0.00	0.00	0.00
stomach, embryo E15.CNhs10603.1252-16G8	3.25	0.00	0.00	0.20
heart, embryo E13.CNhs11013.376-3I9	3.24	0.00	0.36	0.36
heart, neonate N30.CNhs11202.1390-42D2	3.22	1.07	0.27	0.00
thymus, neonate N20.CNhs11186.820-7A2	3.22	1.36	0.39	0.19
pancreas, neonate N16.CNhs11136.787-43B6	3.16	0.00	0.32	0.00
Clontech Mouse Universal Reference Total RNA, pool1.CNhs10609.10001-101A3	3.15	0.68	0.09	0.00
thymus, neonate N10.CNhs11194.748-24E4	3.13	0.91	0.10	0.10
whole body, embryo E17.5, pool1 (internal control).CNhs10749.3139-67G5	3.13	0.35	0.12	0.00
eyeball, neonate N16.CNhs11188.777-19A2	3.10	0.52	0.00	0.52
heart, embryo E16.CNhs11021.457-17C6	3.09	0.15	0.15	0.15
pancreas, neonate N30.CNhs11182.1548-44H5	3.09	0.00	0.00	0.00
Mouse Meningeal cells, donor1.CNhs12132.11716-123C6	3.05	0.00	0.34	0.00
epididymis, adult.CNhs10490.58-23B2	3.03	0.00	0.00	0.25
adrenal gland, neonate N00.CNhs11191.1311-23C1	2.94	0.12	0.35	0.24
testis, neonate N00.CNhs11189.1300-22B7	2.93	0.12	0.00	0.12
thymus, neonate N06.CNhs11197.681-26C4	2.93	0.81	0.10	0.30
small intestine, neonate N16.CNhs11114.790-21I1	2.91	0.29	0.00	0.00
liver, embryo E16.CNhs10523.462-17F5	2.89	0.00	0.00	0.00
Mouse Astrocytes, donor3.CNhs12107.11633-122C4	2.88	0.00	0.00	0.00
liver, embryo E18.CNhs10579.499-43G4	2.88	0.58	0.58	0.29
whole body, embryo E17.5, pool1 (internal control).CNhs10856.3139-67G5	2.88	0.00	0.82	0.00
whole body, neonate N06.CNhs10515.692-21D1	2.87	0.88	0.22	0.44
heart, neonate N25.CNhs11196.1351-25D3	2.85	0.88	0.44	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11208.3139-67G5	2.85	0.47	0.00	0.24
whole body, embryo E17.5, pool1 (internal control).CNhs11184.3139-67G5	2.81	0.56	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10880.3139-67G5	2.80	0.00	0.15	0.15
pancreas, embryo E18.CNhs10580.1535-43I7	2.77	0.31	0.00	0.61
intestine, neonate N06.CNhs11102.688-20B8	2.76	0.25	0.25	0.25
whole body, embryo E17.5, pool1 (internal control).CNhs11096.3139-67G5	2.74	0.18	0.00	0.18
testis, neonate N07.CNhs11222.726-26I4	2.73	0.26	0.13	0.13
stomach, embryo E16.CNhs11022.459-17D4	2.70	0.11	0.22	0.11
thymus, embryo E17.CNhs10581.478-18C1	2.69	0.18	0.36	0.72
heart, embryo E18.CNhs11030.1283-20G3	2.68	0.00	0.00	0.27
kidney, neonate N25.CNhs11122.1353-25F3	2.67	0.16	0.16	0.00
kidney, neonate N20.CNhs11113.832-19I1	2.66	0.44	0.00	0.00
pancreas, adult.CNhs10486.34-16E4	2.65	1.33	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11072.3139-67G5	2.64	0.19	0.19	0.00
bone (os femoris), neonate N02.CNhs11227.1985-43F5	2.59	0.16	0.16	0.16
liver, neonate N00.CNhs11117.641-24F4	2.59	0.65	0.16	0.00
pancreas, neonate N00.CNhs11105.645-26G9	2.58	0.26	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10527.3139-67G5	2.53	0.25	0.00	0.00
liver, neonate N25.CNhs11198.1368-26H1	2.51	0.72	0.36	0.18
pancreas, neonate N02.CNhs11139.1539-43D8	2.50	0.71	0.00	0.00
kidney, neonate N30.CNhs11203.1385-42H1	2.47	0.49	0.12	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10655.3139-67G5	2.47	0.29	0.06	0.11
Follicle Associated Epithelium, pool2.CNhs13211.10262-104D1	2.40	0.32	0.16	0.32
thymus, neonate N02.CNhs11181.1541-43F8	2.40	0.96	0.36	0.00
neurospheres - sympathetic neuron derived, biol_rep3.CNhs13083.11806-124D6	2.37	0.00	0.40	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11080.3139-67G5	2.37	0.51	0.00	0.00
heart, embryo E15.CNhs11017.431-16C8	2.36	0.39	0.20	0.20
heart, embryo E12.CNhs11015.353-12F5	2.35	0.47	0.00	0.00
thymus, embryo E16.CNhs11002.456-26C5	2.34	0.52	0.00	0.13
heart, embryo E17.CNhs11025.479-18E5	2.33	0.23	0.23	0.00
testis, neonate N10.CNhs11204.763-44D9	2.31	0.00	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10840.3139-67G5	2.31	0.19	0.19	0.19
heart, neonate N10.CNhs11118.749-24G1	2.30	0.66	0.00	0.16
visual cortex - wildtype, neonate N15, donor3.CNhs13033.10237-104A3	2.29	0.57	0.00	0.00
Tracheal epithelial cells, differentiation to ciliated epithelial cells, 000hr, biol_rep2.CNhs13740.13368-143G2	2.28	0.00	0.00	0.51
Universal RNA - Mouse Normal Tissues Biochain, pool1.CNhs10613.10008-101B6	2.28	0.23	0.23	0.57
heart, neonate N16.CNhs11209.782-15G1	2.27	1.22	0.32	0.08
corpora quadrigemina, adult.CNhs10501.16-22A4	2.25	0.30	0.00	0.00
heart, neonate N00.CNhs11213.639-21E3	2.22	0.47	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10479.3139-67G5	2.22	0.00	0.44	0.44
prostate, adult.CNhs10470.859-1F8	2.21	0.00	0.00	0.00
liver, neonate N03.CNhs11123.1345-25G2	2.20	0.27	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs11128.3139-67G5	2.17	0.41	0.14	0.14
whole body, embryo E17.5, pool1 (internal control).CNhs11216.3139-67G5	2.17	0.20	0.10	0.10
heart, neonate N03.CNhs11221.1349-25I2	2.14	0.16	0.33	0.33
adrenal gland, embryo E18.CNhs11026.1262-18F5	2.11	0.15	0.00	0.15
medulla oblongata, neonate N30.CNhs11200.1396-42A3	2.11	0.23	0.00	0.00
CD41+ megakaryocyte cancer, donor3.CNhs13506.11778-124A5	2.10	0.00	0.00	0.00
stomach, neonate N30.CNhs11134.1386-42I1	2.07	0.78	0.13	0.26
liver, embryo E17.CNhs10510.481-18A3	2.04	0.00	0.51	0.25
kidney, neonate N00.CNhs11214.646-21G7	2.03	0.56	0.00	0.07
intestine, neonate N30.CNhs11131.1384-42G1	1.99	0.60	0.20	0.20
intestinal mucosa, adult.CNhs10506.860-29I3	1.98	0.00	0.00	0.00
forelimb, embryo E14.CNhs10577.413-26A8	1.97	0.88	0.00	0.00
Mouse hepatocyte, donor6.CNhs13090.11822-124F4	1.95	0.65	0.00	0.00
Tracheal epithelial cells, differentiation to ciliated epithelial cells, 000hr, biol_rep1.CNhs13739.13367-143G1	1.95	0.00	0.00	0.00
forelimb, embryo E15.CNhs11007.437-20E7	1.95	0.56	0.00	0.00
bone (os femoris), neonate N20.CNhs11195.1350-25C3	1.94	0.97	0.97	0.00
thymus, neonate N03.CNhs11137.2104-43C7	1.92	1.48	0.15	0.00
stomach, adult.CNhs10503.33-1H6	1.91	0.00	0.00	1.91
intestine, neonate N00.CNhs11126.644-26D1	1.90	0.00	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10623.3139-67G5	1.87	0.19	0.19	0.28
eyeball, neonate N00.CNhs11207.633-15C6	1.84	0.34	0.14	0.00
Lgr5 positive intestinal stem cells, pool2.CNhs12556.12229-129F6	1.83	0.00	0.00	0.00
corpus striatum, adult.CNhs10487.19-21D8	1.83	0.46	0.00	0.00
thymus, neonate N07.CNhs11211.713-19D3	1.83	1.14	0.15	0.15
visual cortex - wildtype, neonate N60-70, donor2.CNhs13038.10242-104A8	1.81	0.45	0.00	0.00
intestine, neonate N20.CNhs11187.827-18D1	1.80	0.00	0.00	0.00
cerebellum, adult.CNhs10494.15-8B2	1.76	1.17	0.00	0.00
CD326+ enterocyte isolated from mice, treated with RANKL, day03, pool1.CNhs13242.11850-124I5	1.74	0.70	0.00	0.00
Mouse Schwann, donor2.CNhs12573.11746-123F9	1.74	0.00	0.23	0.08
cortex, adult.CNhs10473.12-14D5	1.74	0.87	0.35	0.00
epididymis and seminiferous tubule, neonate N00.CNhs11218.1310-23B1	1.73	0.31	0.10	0.20
intestine, neonate N25.CNhs11121.1352-25E3	1.73	0.43	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10639.3139-67G5	1.73	0.19	0.06	0.06
whole body, embryo E17.5, pool1 (internal control).CNhs11032.3139-67G5	1.67	0.00	0.00	0.00
pituitary gland, embryo E17.CNhs11039.1265-44F5	1.65	0.00	0.00	0.16
ovary, neonate N00.CNhs11217.1299-22I4	1.63	0.16	0.00	0.49
Follicle Associated Epithelium, pool3.CNhs13200.10263-104D2	1.61	0.00	0.23	0.23
medulla oblongata, adult.CNhs10477.17-12C2	1.61	0.16	0.00	0.16
whole body, embryo E17.5, pool1 (internal control).CNhs11048.3139-67G5	1.60	0.29	0.00	0.00
thymus, embryo E18.CNhs10595.1273-19G4	1.59	0.79	0.00	0.40
kidney, neonate N10.CNhs11206.758-6D5	1.58	0.38	0.06	0.00
kidney, embryo E18.CNhs11001.1288-20C7	1.55	0.19	0.39	0.00
SABiosciences XpressRef Mouse Universal Total RNA, pool1.CNhs10611.10003-101A7	1.54	0.70	0.42	0.56
adrenal gland, neonate N25.CNhs11223.1377-27I3	1.51	0.13	0.13	0.00
eyeball, embryo E17.CNhs11023.1261-18D4	1.51	0.45	0.00	0.00
intestine, embryo E12.CNhs11019.1251-16I5	1.49	0.00	0.00	0.21
pancreas, embryo E17.CNhs10599.1558-45G3	1.48	0.59	0.00	0.00
whole body, embryo E14.CNhs10519.395-14B1	1.47	0.00	0.00	0.00
diencephalon, neonate N30.CNhs11201.1388-42B2	1.46	0.49	0.16	0.00
neurospheres - sympathetic neuron derived, biol_rep2.CNhs13082.11805-124D5	1.46	0.00	0.00	0.00
CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl).CNhs13225.11819-124F1	1.44	3.99	0.00	0.00
Lgr5 positive intestinal stem cells, pool1.CNhs12555.12228-129F5	1.44	0.00	0.00	0.00
pituitary gland, embryo E16.CNhs11036.449-43F6	1.43	0.00	0.00	0.00
pituitary gland, embryo E15.CNhs10592.427-16B9	1.42	0.18	0.00	0.18
whole body, embryo E17.5, pool1 (internal control).CNhs11000.3139-67G5	1.37	0.34	0.34	0.00
pituitary gland, adult.CNhs10493.21-1G8	1.36	0.00	0.00	0.00
testis, embryo E16.CNhs11033.470-26G5	1.36	0.19	0.00	0.00
testis, embryo E18.CNhs11027.503-18G5	1.35	0.00	0.17	0.00
visual cortex - wildtype, neonate N30, donor3.CNhs13036.10240-104A6	1.35	0.68	0.00	0.00
mouse fibroblast cell line: CRL-1658 NIH/3T3.CNhs11093.1830-49C7	1.31	0.00	0.00	0.00
GP2+ M cell, pool2.CNhs13231.11846-124I1	1.29	0.00	0.43	0.00
olfactory brain, adult.CNhs10489.18-22I9	1.29	0.64	0.00	0.00
pituitary gland, embryo E14.CNhs11037.398-44A5	1.29	0.00	0.00	0.00
colon, adult.CNhs10468.36-18H7	1.28	0.51	0.00	0.00
Ileum epithelium, pool2.CNhs13232.10253-104C1	1.26	0.25	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10495.3139-67G5	1.24	0.62	0.21	0.21
Lgr5 positive intestinal stem cells, pool3.CNhs12557.12230-129F7	1.23	0.00	0.00	0.00
Mouse Neurons - raphe, donor3.CNhs12619.11645-122D7	1.23	0.00	0.00	0.00
CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl).CNhs13220.11817-124E8	1.22	1.05	0.00	0.00
thymus, embryo E14.CNhs11041.402-44I4	1.22	1.22	0.00	0.00
whole body, embryo E14.5.CNhs10578.420-27D2	1.22	0.00	0.00	0.00
neurospheres - sympathetic neuron derived, biol_rep1.CNhs13081.11804-124D4	1.21	0.00	0.00	0.00
whole body, embryo E12.CNhs10587.857-27C9	1.20	0.00	0.00	0.00
Mouse Neurons - ventral spinal cord, donor1.CNhs12632.11725-123D6	1.18	0.29	0.00	0.00
intestine, embryo E15.CNhs10602.976-16D8	1.16	0.39	0.00	0.00
Mouse Neurons - raphe, donor2.CNhs12636.11740-123F3	1.15	0.13	0.00	0.00
lung, embryo E12.CNhs10522.354-16G2	1.14	0.38	0.00	0.00
forelimb, embryo E12.CNhs10600.359-14H2	1.13	0.38	0.00	0.00
pancreas, embryo E16.CNhs11003.460-26E5	1.13	0.19	0.00	0.00
neurospheres - parasympathetic neuron derived, biol_rep2.CNhs13085.11808-124D8	1.11	0.22	0.00	0.00
stomach, embryo E12.CNhs10588.356-43E3	1.11	0.00	0.00	0.16
whole body, embryo E16.CNhs10514.453-14F2	1.10	0.18	0.00	0.00
Mouse hepatocyte, donor3.CNhs12615.11637-122C8	1.08	0.00	0.00	0.00
neurospheres - enteric neuron derived, biol_rep3.CNhs13089.11812-124E3	1.08	0.00	0.00	0.00
Mouse Schwann, donor1.CNhs12507.11728-123D9	1.06	0.00	0.08	0.08
forelimb, embryo E13.CNhs10589.384-1E2	1.06	0.35	0.00	0.35
hippocampus, adult.CNhs10478.13-16E8	1.05	0.84	0.00	0.00
ST2 (Mesenchymal stem cells) cells, medium change (without induction), 00hr, biol_rep2 (000hC5).CNhs13275.12460-132E3	1.04	0.00	0.00	0.00
diencephalon, adult.CNhs10482.20-12F2	1.04	0.21	0.00	0.21
visual cortex - wildtype, neonate N60-70, donor3.CNhs13039.10243-104A9	1.04	1.04	0.00	0.00
visual cortex - wildtype, neonate N15, donor5.CNhs13820.10349-105D7	1.03	0.34	0.00	0.00
kidney, embryo E17.CNhs11028.483-18I2	1.02	0.00	0.00	0.00
lung, embryo E15.CNhs11020.432-17C5	1.02	0.34	0.17	0.17
liver, embryo E15.CNhs10520.433-16D7	1.01	0.20	0.41	0.00
pancreas, embryo E14.CNhs11012.405-44F4	0.97	0.00	0.00	0.24
neurospheres - parasympathetic neuron derived, biol_rep1.CNhs13084.11807-124D7	0.96	0.24	0.00	0.00
whole body, embryo E17.5, pool1 (internal control).CNhs10511.3139-67G5	0.96	0.32	0.00	0.32
kidney, embryo E14.CNhs10606.411-4I9	0.95	0.00	0.00	0.00
CD326++ enterocyte isolated from mice, treated with RANKL, day03, pool2.CNhs13210.11853-124I8	0.93	0.23	0.00	0.00
hippocampus, neonate N00.CNhs11228.627-43G1	0.93	0.10	0.00	0.00
Mouse Neurons - substantia nigra, donor6.CNhs12643.11770-123I6	0.92	0.15	0.00	0.00
adrenal gland, embryo E17.CNhs11043.1263-45I1	0.92	0.23	0.23	0.00
visual cortex - wildtype, neonate N15, donor2.CNhs13032.10236-104A2	0.92	0.46	0.00	0.00
Mouse hepatocyte, donor8.CNhs13091.11824-124F6	0.90	0.45	0.00	0.00
ovary, embryo E18.CNhs11040.505-44H7	0.89	0.36	0.00	0.00
GP2+ M cell, pool3.CNhs13240.11847-124I2	0.86	0.43	0.00	0.00
testis, neonate N30.CNhs11130.1391-42E2	0.86	0.00	0.00	0.00
lung, embryo E14.CNhs10604.404-26F8	0.81	0.33	0.00	0.00
intestine, adult.CNhs10496.178-9A3	0.79	0.00	0.26	0.00
neurospheres - enteric neuron derived, biol_rep2.CNhs13088.11811-124E2	0.78	0.00	0.00	0.00
pituitary gland, embryo E13.CNhs11009.370-44C7	0.78	0.39	0.00	0.00
cortex, neonate N30.CNhs11107.1392-42F2	0.77	0.00	0.00	0.26
testis, embryo E17.CNhs11029.486-18I5	0.77	0.13	0.13	0.00
spinal cord, adult.CNhs10505.24-13C9	0.74	0.19	0.00	0.19
eyeball, embryo E15.CNhs10593.426-16C9	0.72	0.00	0.00	0.00
intestine, embryo E13.CNhs11010.381-16D5	0.70	0.23	0.00	0.23
lung, embryo E16.CNhs10998.458-17B6	0.70	0.47	0.00	0.47
adrenal gland, embryo E14.CNhs11038.406-44C5	0.69	0.00	0.00	0.00
visual cortex - wildtype, neonate N30, donor1.CNhs13034.10238-104A4	0.69	0.00	0.00	0.00
ST2 (Mesenchymal stem cells) cells, medium change (without induction), 00hr, biol_rep1 (000hC4).CNhs11939.12338-130I7	0.68	0.51	0.00	0.00
whole body, embryo E13.CNhs10512.372-23H2	0.68	0.00	0.00	0.00
CD326++ enterocyte isolated from mice, treated with RANKL, day03, pool1.CNhs13236.11852-124I7	0.67	0.17	0.17	0.00
Ileum epithelium, treated with RANKL, day03, pool3.CNhs13234.10260-104C8	0.67	0.00	0.00	0.00
liver, embryo E14.CNhs10594.409-16E1	0.67	0.67	0.22	0.00
Mouse Neurons - dorsal spinal cord, donor3.CNhs12618.11643-122D5	0.66	0.22	0.00	0.00
eyeball, neonate N01.CNhs11140.1532-43E7	0.64	0.51	0.00	0.13
Mouse Granule cells, donor3.CNhs12108.11636-122C7	0.63	0.00	0.00	0.00
Mouse Granule cells, donor1.CNhs12131.11713-123C3	0.61	0.40	0.00	0.00
adrenal gland, embryo E16.CNhs11004.1254-43D6	0.61	0.30	0.30	0.30
pituitary gland, neonate N00.CNhs11190.1308-22E9	0.61	0.30	0.00	0.00
testis, embryo E13.CNhs11031.389-23F5	0.60	0.00	0.00	0.00
GP2+ M cell, pool1.CNhs13228.11845-124H9	0.57	0.57	0.00	0.00
Mouse Neurons - ventral spinal cord, donor2.CNhs12638.11743-123F6	0.57	0.14	0.14	0.00
kidney, embryo E15.CNhs10997.434-16F8	0.57	0.11	0.11	0.11
Mouse Neurons - substantia nigra, donor4, tech_rep1.CNhs12612.11489-119E4	0.56	0.28	0.00	0.00
Mouse Neurons - ventral spinal cord, donor3.CNhs12113.11648-122E1	0.56	0.19	0.19	0.00
visual cortex - wildtype, neonate N15, donor1.CNhs13031.10235-104A1	0.56	0.00	0.00	0.00
whole body, embryo E11.CNhs11014.324-5I8	0.52	0.00	0.10	0.00
testis, embryo E15.CNhs11034.443-27C5	0.50	0.00	0.00	0.00
vesicular gland, adult.CNhs10491.51-27F8	0.50	0.50	0.00	0.00
testis, neonate N20.CNhs11110.839-18H3	0.48	0.00	0.00	0.00
eyeball, embryo E14.CNhs10521.399-16E2	0.46	0.23	0.00	0.00
Mouse Neurons - cortical, donor1.CNhs12025.11724-123D5	0.41	0.00	0.00	0.00
Mouse Neurons - striatal, donor1.CNhs12134.11723-123D4	0.40	0.00	0.00	0.00
eyeball, embryo E12.CNhs11016.345-16C6	0.39	0.00	0.00	0.00
eyeball, neonate N02.CNhs11205.1551-44G8	0.37	0.19	0.00	0.28
pituitary gland, embryo E12.CNhs11018.346-16E6	0.36	0.18	0.00	0.00
neurospheres - enteric neuron derived, biol_rep1.CNhs13087.11810-124E1	0.32	0.00	0.00	0.00
pancreas, embryo E15.CNhs11042.1556-45F2	0.30	0.00	0.00	0.00
Mouse Neurons - dorsal spinal cord, donor2.CNhs12635.11738-123F1	0.29	0.00	0.00	0.00
Sox2+ Supporting cells - organ of corti, pool1.CNhs12532.12157-128G6	0.28	0.28	0.00	0.00
neurospheres - parasympathetic neuron derived, biol_rep3.CNhs13086.11809-124D9	0.28	0.28	0.00	0.00
Mouse Neurons - cortical, donor2.CNhs11947.11742-123F5	0.27	0.14	0.00	0.00
Mouse Neurons - hippocampal, donor1.CNhs12133.11721-123D2	0.24	0.00	0.00	0.00
forelimb, embryo E11.CNhs10596.335-25E2	0.22	0.00	0.00	0.22
Mouse Neurons - cortical, donor3.CNhs12112.11647-122D9	0.21	0.00	0.00	0.00
gonad, embryo E13.CNhs11044.1564-45I6	0.20	0.00	0.00	0.00
Ileum epithelium, pool1.CNhs13199.10252-104B9	0.19	0.00	0.00	0.00
liver, embryo E12.CNhs10601.355-15F8	0.17	0.33	0.00	0.00
corpus striatum, neonate N00.CNhs11226.630-43F1	0.13	0.13	0.00	0.00
Mouse Neurons - hippocampal, donor2.CNhs12359.11739-123F2	0.10	0.00	0.00	0.00
Mouse Neurons - striatal, donor2.CNhs12360.11741-123F4	0.09	0.18	0.09	0.00
Atoh1+ Inner ear hair cells - organ of corti, pool1.CNhs12533.12158-128G7	0.00	0.00	0.00	0.00
CD326+ enterocyte isolated from mice, treated with RANKL, day03, pool2.CNhs13233.11851-124I6	0.00	0.00	0.00	0.00
CD326+ enterocyte, pool1.CNhs13542.11848-124I3	0.00	0.00	0.30	0.00
CD326+ enterocyte, pool2.CNhs13197.11849-124I4	0.00	0.00	0.00	0.00
J2E erythroblastic leukemia response to erythropoietin, 00hr00min, biol_rep1.CNhs12449.13063-139I3	0.00	0.00	0.00	0.00
J2E erythroblastic leukemia response to erythropoietin, 00hr00min, biol_rep2.CNhs12668.13129-140G6	0.00	0.00	0.00	0.00
J2E erythroblastic leukemia response to erythropoietin, 00hr00min, biol_rep3.CNhs12770.13195-141E9	0.00	0.00	0.00	0.00
Mouse Granule cells, donor2.CNhs12357.11731-123E3	0.00	0.00	0.00	0.00
Mouse Neurons - hippocampal, donor3.CNhs12110.11644-122D6	0.00	0.00	0.00	0.00
Mouse Neurons - striatal, donor3.CNhs12111.11646-122D8	0.00	0.00	0.00	0.00
ST2 (Mesenchymal stem cells) cells, medium change (without induction), 00hr, biol_rep3 (000hC6).CNhs13324.12582-133I8	0.00	0.00	0.00	0.35
TSt-4/DLL1 feeder cells, biol_rep1.CNhs13407.12971-138H1	0.00	0.00	0.00	0.00
TSt-4/DLL1 feeder cells, biol_rep2.CNhs13408.12987-138I8	0.00	0.00	0.00	0.00
TSt-4/DLL1 feeder cells, biol_rep3.CNhs13409.13003-139B6	0.00	0.00	0.00	0.00
liver, embryo E13.CNhs10524.378-3H6	0.00	0.00	0.00	0.00
testis, adult.CNhs10504.57-7G5	0.00	0.00	0.00	0.00
visual cortex - wildtype, neonate N30, donor2.CNhs13035.10239-104A5	0.00	0.00	0.00	0.00
visual cortex - wildtype, neonate N60-70, donor1.CNhs13037.10241-104A7	0.00	0.45	0.00	0.00

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p1@Map3k8
p2@Map3k8
p3@Map3k8
p5@Map3k8

• Click each plot point to find sample in table

ENCODE TF ChIP-seq peak enrichment analysis Analyst: Erik Arner <br>Summary: For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><br><br>link to source dataset.<br>data

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No analysis results for this cluster

Details<b>Summary:</b>It includes sequences from the international sequence collaboration, Swiss-Prot, and RefSeq. The RefSeq subset of this file is also available as gene2refseq.<br><br>links to source dataset.<br>human <br>mouse

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GeneID:	26410
LocusTag:	-
chromosome:	18
map location:	18 A1, 18 0.0 cM, 18 A1;;18 0.0 cM
type of gene:	protein-coding
Symbol from nomenclature authority:	Map3k8
Full name from nomenclature authority:	mitogen-activated protein kinase kinase kinase 8
Nomenclature status:	O
Other designations:	COT proto-oncogene serine/threonine-protein kinase, cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, mitogen activated protein kinase kinase kinase 8, proto-oncogene c-Cot, serine/threonine-protein kinase cot, tumor progression locus 2, COT proto-oncogene serine/threonine-protein kinase;;cancer Osaka thyroid oncogene;;cancer Osaka thyroid, oncogene;;mitogen activated protein kinase kinase kinase 8;;proto-oncogene c-Cot;;serine/threonine-protein kinase cot;;tumor progression locus 2
Modification date:	18.12.2011