MCL coexpression mm9:1284
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005626 | insoluble fraction | 0.000320721918700239 |
GO:0005605 | basal lamina | 0.000633274535833115 |
GO:0042383 | sarcolemma | 0.000633274535833115 |
GO:0030018 | Z disc | 0.000633274535833115 |
GO:0031674 | I band | 0.000653173538217342 |
GO:0005604 | basement membrane | 0.00169525293364805 |
GO:0030017 | sarcomere | 0.00169525293364805 |
GO:0044449 | contractile fiber part | 0.00169525293364805 |
GO:0030016 | myofibril | 0.00169525293364805 |
GO:0043292 | contractile fiber | 0.00169525293364805 |
GO:0005886 | plasma membrane | 0.00169525293364805 |
GO:0044420 | extracellular matrix part | 0.00202213373248082 |
GO:0006200 | ATP catabolic process | 0.00507115656574754 |
GO:0009207 | purine ribonucleoside triphosphate catabolic process | 0.00507115656574754 |
GO:0007517 | muscle development | 0.00526387084088259 |
GO:0009137 | purine nucleoside diphosphate catabolic process | 0.00591586310026468 |
GO:0009181 | purine ribonucleoside diphosphate catabolic process | 0.00591586310026468 |
GO:0009203 | ribonucleoside triphosphate catabolic process | 0.00591586310026468 |
GO:0009146 | purine nucleoside triphosphate catabolic process | 0.00676043075353872 |
GO:0009179 | purine ribonucleoside diphosphate metabolic process | 0.00676043075353872 |
GO:0009135 | purine nucleoside diphosphate metabolic process | 0.00676043075353872 |
GO:0009154 | purine ribonucleotide catabolic process | 0.00771507489645553 |
GO:0009191 | ribonucleoside diphosphate catabolic process | 0.00771507489645553 |
GO:0009143 | nucleoside triphosphate catabolic process | 0.00788587284542905 |
GO:0009185 | ribonucleoside diphosphate metabolic process | 0.00788587284542905 |
GO:0045213 | neurotransmitter receptor metabolic process | 0.00788587284542905 |
GO:0009134 | nucleoside diphosphate catabolic process | 0.00788587284542905 |
GO:0005578 | proteinaceous extracellular matrix | 0.00791926210191326 |
GO:0006195 | purine nucleotide catabolic process | 0.00827948596959745 |
GO:0009261 | ribonucleotide catabolic process | 0.00827948596959745 |
GO:0046716 | muscle maintenance | 0.0102999713008809 |
GO:0017110 | nucleoside-diphosphatase activity | 0.0110858634557424 |
GO:0030168 | platelet activation | 0.0114761859250077 |
GO:0015269 | calcium-activated potassium channel activity | 0.0114761859250077 |
GO:0016010 | dystrophin-associated glycoprotein complex | 0.0121607766733126 |
GO:0022839 | ion gated channel activity | 0.0124610329072939 |
GO:0009132 | nucleoside diphosphate metabolic process | 0.0124610329072939 |
GO:0005227 | calcium activated cation channel activity | 0.0130653532658187 |
GO:0000267 | cell fraction | 0.0177110898669781 |
GO:0009166 | nucleotide catabolic process | 0.0194918841001994 |
GO:0043112 | receptor metabolic process | 0.0216042991580266 |
GO:0065008 | regulation of biological quality | 0.0246739804297449 |
GO:0045121 | lipid raft | 0.027994529518183 |
GO:0030055 | cell-matrix junction | 0.0281606306010075 |
GO:0046034 | ATP metabolic process | 0.0314554543040692 |
GO:0005509 | calcium ion binding | 0.0360135941448607 |
GO:0009205 | purine ribonucleoside triphosphate metabolic process | 0.0360135941448607 |
GO:0009199 | ribonucleoside triphosphate metabolic process | 0.0360135941448607 |
GO:0009144 | purine nucleoside triphosphate metabolic process | 0.0360135941448607 |
GO:0007596 | blood coagulation | 0.0360135941448607 |
GO:0007599 | hemostasis | 0.0360135941448607 |
GO:0008076 | voltage-gated potassium channel complex | 0.0360135941448607 |
GO:0050817 | coagulation | 0.0360135941448607 |
GO:0009141 | nucleoside triphosphate metabolic process | 0.0366497842386897 |
GO:0005856 | cytoskeleton | 0.0366919040790318 |
GO:0009150 | purine ribonucleotide metabolic process | 0.0403629970653441 |
GO:0050878 | regulation of body fluid levels | 0.041881593998687 |
GO:0009259 | ribonucleotide metabolic process | 0.041881593998687 |
GO:0016323 | basolateral plasma membrane | 0.041881593998687 |
GO:0006163 | purine nucleotide metabolic process | 0.0435225948139612 |
GO:0042060 | wound healing | 0.0456828279462791 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
primary circulatory organ | 3.42e-10 | 18 |
heart | 3.42e-10 | 18 |
primitive heart tube | 3.42e-10 | 18 |
primary heart field | 3.42e-10 | 18 |
anterior lateral plate mesoderm | 3.42e-10 | 18 |
heart tube | 3.42e-10 | 18 |
heart primordium | 3.42e-10 | 18 |
cardiac mesoderm | 3.42e-10 | 18 |
cardiogenic plate | 3.42e-10 | 18 |
heart rudiment | 3.42e-10 | 18 |
cardiovascular system | 4.56e-09 | 23 |
circulatory system | 4.56e-09 | 23 |
epithelial bud | 1.22e-08 | 17 |
compound organ | 4.56e-08 | 43 |
splanchnic layer of lateral plate mesoderm | 7.54e-08 | 33 |
lung | 8.54e-07 | 14 |
respiratory tube | 8.54e-07 | 14 |
respiration organ | 8.54e-07 | 14 |
pair of lungs | 8.54e-07 | 14 |
lung primordium | 8.54e-07 | 14 |
lung bud | 8.54e-07 | 14 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.00973143 |
MA0004.1 | 0.536396 |
MA0006.1 | 0.359699 |
MA0007.1 | 0.52077 |
MA0009.1 | 0.987341 |
MA0014.1 | 0.304529 |
MA0017.1 | 1.00628 |
MA0019.1 | 0.800946 |
MA0024.1 | 0.942716 |
MA0025.1 | 1.22395 |
MA0027.1 | 2.64231 |
MA0028.1 | 0.370592 |
MA0029.1 | 0.920529 |
MA0030.1 | 0.927235 |
MA0031.1 | 0.890871 |
MA0038.1 | 0.686534 |
MA0040.1 | 1.00009 |
MA0041.1 | 1.15799 |
MA0042.1 | 1.12834 |
MA0043.1 | 1.08567 |
MA0046.1 | 1.02391 |
MA0048.1 | 1.50576 |
MA0050.1 | 0.57678 |
MA0051.1 | 0.695779 |
MA0052.1 | 1.00829 |
MA0055.1 | 0.807132 |
MA0056.1 | 0 |
MA0057.1 | 0.149949 |
MA0058.1 | 0.436487 |
MA0059.1 | 0.449345 |
MA0060.1 | 0.275911 |
MA0061.1 | 0.307097 |
MA0063.1 | 0 |
MA0066.1 | 1.61836 |
MA0067.1 | 1.33603 |
MA0068.1 | 0.911705 |
MA0069.1 | 1.00864 |
MA0070.1 | 0.998765 |
MA0071.1 | 0.575909 |
MA0072.1 | 0.990133 |
MA0073.1 | 4.53692 |
MA0074.1 | 0.638014 |
MA0076.1 | 0.407465 |
MA0077.1 | 0.968053 |
MA0078.1 | 0.729877 |
MA0081.1 | 0.473489 |
MA0083.1 | 2.45852 |
MA0084.1 | 1.66561 |
MA0087.1 | 1.04109 |
MA0088.1 | 0.358337 |
MA0089.1 | 0 |
MA0090.1 | 0.500693 |
MA0091.1 | 2.32562 |
MA0092.1 | 0.501022 |
MA0093.1 | 0.379257 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.626021 |
MA0101.1 | 0.458688 |
MA0103.1 | 0.398766 |
MA0105.1 | 0.199622 |
MA0106.1 | 0.737893 |
MA0107.1 | 0.392331 |
MA0108.2 | 0.824407 |
MA0109.1 | 0 |
MA0111.1 | 0.515457 |
MA0113.1 | 0.708789 |
MA0114.1 | 0.822296 |
MA0115.1 | 1.08851 |
MA0116.1 | 0.359483 |
MA0117.1 | 1.05576 |
MA0119.1 | 0.459301 |
MA0122.1 | 1.07591 |
MA0124.1 | 1.28237 |
MA0125.1 | 1.20757 |
MA0130.1 | 0 |
MA0131.1 | 0.796279 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.1226 |
MA0136.1 | 1.58388 |
MA0139.1 | 0.243463 |
MA0140.1 | 0.625902 |
MA0141.1 | 0.419361 |
MA0142.1 | 0.876028 |
MA0143.1 | 0.725672 |
MA0144.1 | 0.307873 |
MA0145.1 | 0.119202 |
MA0146.1 | 0.990842 |
MA0147.1 | 0.320675 |
MA0148.1 | 1.3627 |
MA0149.1 | 1.17328 |
MA0062.2 | 0.204999 |
MA0035.2 | 0.630778 |
MA0039.2 | 0.769467 |
MA0138.2 | 0.788113 |
MA0002.2 | 0.246463 |
MA0137.2 | 0.416331 |
MA0104.2 | 0.261255 |
MA0047.2 | 1.64036 |
MA0112.2 | 1.24549 |
MA0065.2 | 0.380324 |
MA0150.1 | 0.520653 |
MA0151.1 | 0 |
MA0152.1 | 0.685852 |
MA0153.1 | 1.13945 |
MA0154.1 | 1.49271 |
MA0155.1 | 0.414701 |
MA0156.1 | 1.84703 |
MA0157.1 | 0.843181 |
MA0158.1 | 0 |
MA0159.1 | 0.331229 |
MA0160.1 | 0.556423 |
MA0161.1 | 0 |
MA0162.1 | 0.397553 |
MA0163.1 | 0.0423021 |
MA0164.1 | 0.658997 |
MA0080.2 | 1.01893 |
MA0018.2 | 0.669032 |
MA0099.2 | 0.781628 |
MA0079.2 | 0.0520572 |
MA0102.2 | 1.7182 |
MA0258.1 | 1.4396 |
MA0259.1 | 0.309517 |
MA0442.1 | 0 |