MCL coexpression mm9:2068
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr13:38071380..38071398,- | p@chr13:38071380..38071398 - |
| Mm9::chr3:65185318..65185322,- | p@chr3:65185318..65185322 - |
| Mm9::chr6:28838574..28838577,+ | p@chr6:28838574..28838577 + |
| Mm9::chr6:88454974..88454978,- | p@chr6:88454974..88454978 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0005783 | endoplasmic reticulum | 0.00347010480930672 |
| GO:0005784 | translocon complex | 0.0111744080782777 |
| GO:0005791 | rough endoplasmic reticulum | 0.0111744080782777 |
| GO:0030867 | rough endoplasmic reticulum membrane | 0.0111744080782777 |
| GO:0006886 | intracellular protein transport | 0.0159407093075002 |
| GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.0159407093075002 |
| GO:0022884 | macromolecule transmembrane transporter activity | 0.0159407093075002 |
| GO:0046907 | intracellular transport | 0.0159407093075002 |
| GO:0008320 | protein transmembrane transporter activity | 0.0159407093075002 |
| GO:0006613 | cotranslational protein targeting to membrane | 0.0159407093075002 |
| GO:0030176 | integral to endoplasmic reticulum membrane | 0.0159407093075002 |
| GO:0015031 | protein transport | 0.0159407093075002 |
| GO:0031227 | intrinsic to endoplasmic reticulum membrane | 0.0159407093075002 |
| GO:0045184 | establishment of protein localization | 0.0159407093075002 |
| GO:0008104 | protein localization | 0.0159407093075002 |
| GO:0051649 | establishment of cellular localization | 0.0159407093075002 |
| GO:0006612 | protein targeting to membrane | 0.0159407093075002 |
| GO:0051641 | cellular localization | 0.0159407093075002 |
| GO:0033036 | macromolecule localization | 0.0159407093075002 |
| GO:0044444 | cytoplasmic part | 0.0159407093075002 |
| GO:0009306 | protein secretion | 0.0159407093075002 |
| GO:0031301 | integral to organelle membrane | 0.0253324253186313 |
| GO:0065002 | intracellular protein transport across a membrane | 0.0255365256537682 |
| GO:0031300 | intrinsic to organelle membrane | 0.0255365256537682 |
| GO:0005789 | endoplasmic reticulum membrane | 0.0311753307934355 |
| GO:0042175 | nuclear envelope-endoplasmic reticulum network | 0.0312558327928293 |
| GO:0044432 | endoplasmic reticulum part | 0.0329716736381077 |
| GO:0015399 | primary active transmembrane transporter activity | 0.0489871804209735 |
| GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.0489871804209735 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| immaterial anatomical entity | 6.57e-15 | 79 |
| trunk | 1.03e-12 | 90 |
| trunk region element | 1.07e-12 | 79 |
| anatomical space | 1.05e-10 | 57 |
| anatomical cavity | 3.02e-10 | 39 |
| body cavity precursor | 3.38e-10 | 38 |
| body cavity | 1.20e-09 | 37 |
| body cavity or lining | 1.20e-09 | 37 |
| pancreas | 1.83e-08 | 12 |
| viscus | 2.10e-07 | 19 |
| subdivision of trunk | 2.28e-07 | 66 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0356887 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 0.497533 |
| MA0007.1 | 1.61215 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 0.0809287 |
| MA0017.1 | 0.528196 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 1.39562 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 0.509589 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 0.846479 |
| MA0040.1 | 1.16866 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 0.266382 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 0.396346 |
| MA0056.1 | 0 |
| MA0057.1 | 0.251896 |
| MA0058.1 | 0.581673 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 0.403071 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 2.83575 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 0.00221226 |
| MA0074.1 | 0.795862 |
| MA0076.1 | 0.550092 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 0.621611 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 1.1032 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 0.703314 |
| MA0092.1 | 2.65214 |
| MA0093.1 | 0.519148 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 0.540576 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 0.869608 |
| MA0114.1 | 0.43587 |
| MA0115.1 | 1.25852 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 1.22527 |
| MA0119.1 | 0.606338 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 0.78318 |
| MA0141.1 | 0.563066 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 1.11951 |
| MA0145.1 | 0.21199 |
| MA0146.1 | 0.313734 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 0.611881 |
| MA0062.2 | 0.319836 |
| MA0035.2 | 0.788288 |
| MA0039.2 | 0.0220513 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.608441 |
| MA0065.2 | 0.212467 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 0.263609 |
| MA0155.1 | 0.230016 |
| MA0156.1 | 0.549102 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 0.465802 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 0.10667 |
| MA0163.1 | 0.0996272 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 0.534538 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 0.00774881 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 1.07695 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
