MCL coexpression mm9:486
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:109005654..109005691,- | p1@E030025P04Rik |
Mm9::chr19:24200299..24200336,- | p@chr19:24200299..24200336 - |
Mm9::chr19:60220585..60220600,+ | p1@ENSMUST00000065383 |
Mm9::chr3:79594253..79594277,- | p@chr3:79594253..79594277 - |
Mm9::chr4:88526110..88526132,- | p1@Ifne |
Mm9::chr6:144996156..144996180,- | p4@Bcat1 |
Mm9::chr6:82855186..82855200,- | p@chr6:82855186..82855200 - |
Mm9::chr8:108053276..108053315,- | p@chr8:108053276..108053315 - |
Mm9::chr9:53916368..53916376,- | p4@Tnfaip8l3 |
Mm9::chr9:8899828..8899855,+ | p3@Pgr |
Mm9::chr9:8900409..8900425,+ | p2@Pgr |
Mm9::chr9:8900459..8900489,+ | p1@Pgr |
Mm9::chr9:8900490..8900502,+ | p4@Pgr |
Mm9::chr9:8900563..8900574,+ | p5@Pgr |
Mm9::chr9:8901535..8901549,+ | p@chr9:8901535..8901549 + |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0009082 | branched chain family amino acid biosynthetic process | 0.0289243744861156 |
GO:0050847 | progesterone receptor signaling pathway | 0.0289243744861156 |
GO:0004084 | branched-chain-amino-acid transaminase activity | 0.0289243744861156 |
GO:0002070 | epithelial cell maturation | 0.043176633121409 |
GO:0009083 | branched chain family amino acid catabolic process | 0.043176633121409 |
GO:0002064 | epithelial cell development | 0.043176633121409 |
GO:0009081 | branched chain family amino acid metabolic process | 0.043176633121409 |
GO:0001542 | ovulation from ovarian follicle | 0.043176633121409 |
GO:0030728 | ovulation | 0.043176633121409 |
GO:0030518 | steroid hormone receptor signaling pathway | 0.043176633121409 |
GO:0030522 | intracellular receptor-mediated signaling pathway | 0.043176633121409 |
GO:0030879 | mammary gland development | 0.043176633121409 |
GO:0050678 | regulation of epithelial cell proliferation | 0.043176633121409 |
GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism | 0.043176633121409 |
GO:0008483 | transaminase activity | 0.043176633121409 |
GO:0022601 | menstrual cycle phase | 0.043176633121409 |
GO:0022602 | menstrual cycle process | 0.043176633121409 |
GO:0015985 | energy coupled proton transport, down electrochemical gradient | 0.043176633121409 |
GO:0050673 | epithelial cell proliferation | 0.043176633121409 |
GO:0015986 | ATP synthesis coupled proton transport | 0.043176633121409 |
GO:0008652 | amino acid biosynthetic process | 0.043176633121409 |
GO:0016769 | transferase activity, transferring nitrogenous groups | 0.043176633121409 |
GO:0008585 | female gonad development | 0.043176633121409 |
GO:0007292 | female gamete generation | 0.043176633121409 |
GO:0006754 | ATP biosynthetic process | 0.043176633121409 |
GO:0006753 | nucleoside phosphate metabolic process | 0.043176633121409 |
GO:0046933 | hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.043176633121409 |
GO:0046545 | development of primary female sexual characteristics | 0.043176633121409 |
GO:0030855 | epithelial cell differentiation | 0.043176633121409 |
GO:0046660 | female sex differentiation | 0.043176633121409 |
GO:0016469 | proton-transporting two-sector ATPase complex | 0.043176633121409 |
GO:0046961 | hydrogen ion transporting ATPase activity, rotational mechanism | 0.043176633121409 |
GO:0042698 | menstrual cycle | 0.043176633121409 |
GO:0046034 | ATP metabolic process | 0.043176633121409 |
GO:0009145 | purine nucleoside triphosphate biosynthetic process | 0.043176633121409 |
GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 0.043176633121409 |
GO:0009201 | ribonucleoside triphosphate biosynthetic process | 0.043176633121409 |
GO:0009063 | amino acid catabolic process | 0.043176633121409 |
GO:0005496 | steroid binding | 0.043176633121409 |
GO:0003707 | steroid hormone receptor activity | 0.043176633121409 |
GO:0019829 | cation-transporting ATPase activity | 0.043176633121409 |
GO:0004879 | ligand-dependent nuclear receptor activity | 0.043176633121409 |
GO:0009142 | nucleoside triphosphate biosynthetic process | 0.043176633121409 |
GO:0009205 | purine ribonucleoside triphosphate metabolic process | 0.043176633121409 |
GO:0009199 | ribonucleoside triphosphate metabolic process | 0.043176633121409 |
GO:0006119 | oxidative phosphorylation | 0.043176633121409 |
GO:0008406 | gonad development | 0.043176633121409 |
GO:0009144 | purine nucleoside triphosphate metabolic process | 0.043176633121409 |
GO:0015992 | proton transport | 0.043176633121409 |
GO:0048608 | reproductive structure development | 0.043176633121409 |
GO:0006752 | group transfer coenzyme metabolic process | 0.043176633121409 |
GO:0044249 | cellular biosynthetic process | 0.043176633121409 |
GO:0009141 | nucleoside triphosphate metabolic process | 0.043176633121409 |
GO:0044270 | nitrogen compound catabolic process | 0.043176633121409 |
GO:0009310 | amine catabolic process | 0.043176633121409 |
GO:0009152 | purine ribonucleotide biosynthetic process | 0.043176633121409 |
GO:0006818 | hydrogen transport | 0.043176633121409 |
GO:0045137 | development of primary sexual characteristics | 0.043176633121409 |
GO:0009309 | amine biosynthetic process | 0.043176633121409 |
GO:0015662 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | 0.043176633121409 |
GO:0009260 | ribonucleotide biosynthetic process | 0.043176633121409 |
GO:0009150 | purine ribonucleotide metabolic process | 0.044532669425093 |
GO:0006164 | purine nucleotide biosynthetic process | 0.044532669425093 |
GO:0009259 | ribonucleotide metabolic process | 0.0449529148313214 |
GO:0005923 | tight junction | 0.0449529148313214 |
GO:0048609 | reproductive process in a multicellular organism | 0.0449529148313214 |
GO:0032504 | multicellular organism reproduction | 0.0449529148313214 |
GO:0007548 | sex differentiation | 0.0449529148313214 |
GO:0048469 | cell maturation | 0.0449529148313214 |
GO:0006163 | purine nucleotide metabolic process | 0.0449529148313214 |
GO:0048732 | gland development | 0.0449529148313214 |
GO:0044271 | nitrogen compound biosynthetic process | 0.0455191505253952 |
GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | 0.0478295860260173 |
GO:0009108 | coenzyme biosynthetic process | 0.0483403062850561 |
GO:0003006 | reproductive developmental process | 0.0494075198078521 |
GO:0043296 | apical junction complex | 0.0496125512930327 |
GO:0016327 | apicolateral plasma membrane | 0.0496125512930327 |
GO:0015078 | hydrogen ion transmembrane transporter activity | 0.0496125512930327 |
GO:0021700 | developmental maturation | 0.0496125512930327 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
female reproductive system | 1.40e-47 | 9 |
female reproductive organ | 2.45e-42 | 8 |
female organism | 9.32e-39 | 11 |
internal female genitalia | 1.74e-27 | 5 |
reproductive structure | 2.09e-23 | 26 |
reproductive system | 2.09e-23 | 26 |
embryonic uterus | 2.84e-22 | 4 |
uterus | 2.84e-22 | 4 |
internal genitalia | 1.83e-21 | 9 |
reproductive organ | 6.40e-21 | 24 |
extraembryonic membrane | 1.94e-16 | 3 |
extraembryonic structure | 1.94e-16 | 3 |
membranous layer | 1.94e-16 | 3 |
female gonad | 2.19e-16 | 3 |
placenta | 1.03e-11 | 2 |
chorion | 1.03e-11 | 2 |
allantois | 1.03e-11 | 2 |
renal system | 1.69e-09 | 19 |
somatic layer of lateral plate mesoderm | 8.73e-08 | 3 |
external genitalia | 1.61e-07 | 17 |
indifferent external genitalia | 1.61e-07 | 17 |
indifferent gonad | 1.61e-07 | 17 |
gonad | 4.31e-07 | 18 |
gonad primordium | 4.31e-07 | 18 |
urinary system structure | 4.73e-07 | 18 |
uterus or analog | 6.50e-07 | 1 |
vagina | 7.38e-07 | 1 |
oviduct | 8.36e-07 | 1 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.0773439 |
MA0004.1 | 0.239244 |
MA0006.1 | 0.37642 |
MA0007.1 | 0.227553 |
MA0009.1 | 0.623671 |
MA0014.1 | 0.0468601 |
MA0017.1 | 0.135289 |
MA0019.1 | 0.456268 |
MA0024.1 | 0.582844 |
MA0025.1 | 0.845702 |
MA0027.1 | 2.24512 |
MA0028.1 | 0.12472 |
MA0029.1 | 0.562703 |
MA0030.1 | 0.568779 |
MA0031.1 | 1.32597 |
MA0038.1 | 0.942753 |
MA0040.1 | 0.635404 |
MA0041.1 | 0.536212 |
MA0042.1 | 0.172351 |
MA0043.1 | 0.71494 |
MA0046.1 | 0.657417 |
MA0048.1 | 0.102771 |
MA0050.1 | 0.270164 |
MA0051.1 | 0.366328 |
MA0052.1 | 0.642973 |
MA0055.1 | 0.229093 |
MA0056.1 | 0 |
MA0057.1 | 0.703408 |
MA0058.1 | 0.968034 |
MA0059.1 | 1.00391 |
MA0060.1 | 0.071412 |
MA0061.1 | 0.0877629 |
MA0063.1 | 0 |
MA0066.1 | 2.49109 |
MA0067.1 | 0.953264 |
MA0068.1 | 0.0945752 |
MA0069.1 | 0.643292 |
MA0070.1 | 0.634186 |
MA0071.1 | 0.269487 |
MA0072.1 | 0.626238 |
MA0073.1 | 1.14566 |
MA0074.1 | 0.318792 |
MA0076.1 | 0.148159 |
MA0077.1 | 0.605975 |
MA0078.1 | 1.80761 |
MA0081.1 | 1.07159 |
MA0083.1 | 0.714187 |
MA0084.1 | 1.27474 |
MA0087.1 | 0.673355 |
MA0088.1 | 0.143884 |
MA0089.1 | 0 |
MA0090.1 | 0.212772 |
MA0091.1 | 0.24961 |
MA0092.1 | 1.79744 |
MA0093.1 | 0.40751 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.309116 |
MA0101.1 | 0.182791 |
MA0103.1 | 0.14251 |
MA0105.1 | 0.341877 |
MA0106.1 | 0.401864 |
MA0107.1 | 0.138378 |
MA0108.2 | 1.19989 |
MA0109.1 | 0 |
MA0111.1 | 1.1901 |
MA0113.1 | 0.983782 |
MA0114.1 | 0.291992 |
MA0115.1 | 0.717599 |
MA0116.1 | 0.37608 |
MA0117.1 | 0.686999 |
MA0119.1 | 0.183219 |
MA0122.1 | 0.705806 |
MA0124.1 | 0.901619 |
MA0125.1 | 0.830088 |
MA0130.1 | 0 |
MA0131.1 | 0.452196 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.749615 |
MA0136.1 | 0.891604 |
MA0139.1 | 1.67613 |
MA0140.1 | 0.30902 |
MA0141.1 | 0.155997 |
MA0142.1 | 0.522654 |
MA0143.1 | 0.391481 |
MA0144.1 | 0.617592 |
MA0145.1 | 0.541572 |
MA0146.1 | 0.00683492 |
MA0147.1 | 0.31605 |
MA0148.1 | 0.252062 |
MA0149.1 | 0.18682 |
MA0062.2 | 0.354916 |
MA0035.2 | 0.312946 |
MA0039.2 | 0.242567 |
MA0138.2 | 0.445088 |
MA0002.2 | 0.208749 |
MA0137.2 | 0.467774 |
MA0104.2 | 0.229221 |
MA0047.2 | 0.357963 |
MA0112.2 | 0.0124337 |
MA0065.2 | 2.42777 |
MA0150.1 | 1.20484 |
MA0151.1 | 0 |
MA0152.1 | 0.358055 |
MA0153.1 | 0.765498 |
MA0154.1 | 0.247047 |
MA0155.1 | 0.0157857 |
MA0156.1 | 0.45173 |
MA0157.1 | 1.23539 |
MA0158.1 | 0 |
MA0159.1 | 0.332142 |
MA0160.1 | 0.254455 |
MA0161.1 | 0 |
MA0162.1 | 0.0853381 |
MA0163.1 | 0.0738452 |
MA0164.1 | 0.335886 |
MA0080.2 | 0.848376 |
MA0018.2 | 0.344133 |
MA0099.2 | 0.439458 |
MA0079.2 | 1.24442 |
MA0102.2 | 1.32652 |
MA0258.1 | 0.0789466 |
MA0259.1 | 0.299239 |
MA0442.1 | 0 |