Novel motif:69

name:	motif69_RYKNAAATC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0097045	phosphatidylserine exposure on blood platelet	2.812123e-13
GO:0046836	glycolipid transport	5.035282e-11
GO:0051024	positive regulation of immunoglobulin secretion	1.409144e-10
GO:0032655	regulation of interleukin-12 production	2.621958e-10
GO:0007610	behavior	3.700626e-10
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	5.214721e-10
GO:0045429	positive regulation of nitric oxide biosynthetic process	1.606504e-9
GO:0050820	positive regulation of coagulation	3.005781e-9
GO:0030194	positive regulation of blood coagulation	3.555467e-9
GO:0045187	regulation of circadian sleep/wake cycle, sleep	3.997379e-9
GO:0006954	inflammatory response	5.335006e-9
GO:0006952	defense response	7.725291e-9
GO:0022410	circadian sleep/wake cycle process	8.452588e-9
GO:2000366	positive regulation of STAT protein import into nucleus	1.115811e-8
GO:0070091	glucagon secretion	1.115811e-8
GO:0018283	iron incorporation into metallo-sulfur cluster	1.275347e-8
GO:0002384	hepatic immune response	1.344987e-8
GO:0034121	regulation of toll-like receptor signaling pathway	1.476102e-8
GO:0045765	regulation of angiogenesis	1.668577e-8
GO:0042745	circadian sleep/wake cycle	1.735736e-8
GO:0051240	positive regulation of multicellular organismal process	1.757710e-8
GO:0001764	neuron migration	2.533109e-8
GO:0046851	negative regulation of bone remodeling	2.954563e-8
GO:0042752	regulation of circadian rhythm	3.813053e-8
GO:0048512	circadian behavior	5.085929e-8
GO:0007565	female pregnancy	6.314746e-8
GO:0006959	humoral immune response	6.684619e-8
GO:0051239	regulation of multicellular organismal process	7.932214e-8
GO:0051023	regulation of immunoglobulin secretion	9.251197e-8
GO:0060124	positive regulation of growth hormone secretion	9.751988e-8
GO:0001781	neutrophil apoptosis	9.808942e-8
GO:0032695	negative regulation of interleukin-12 production	9.836226e-8
GO:0002543	activation of blood coagulation via clotting cascade	1.050573e-7
GO:0006955	immune response	1.155558e-7
GO:0009408	response to heat	1.198794e-7
GO:0046850	regulation of bone remodeling	1.199731e-7
GO:0018065	protein-cofactor linkage	1.563636e-7
GO:0010757	negative regulation of plasminogen activation	1.956321e-7
GO:0009597	detection of virus	2.155933e-7
GO:0010755	regulation of plasminogen activation	3.112024e-7
GO:0060123	regulation of growth hormone secretion	3.440450e-7
GO:0034104	negative regulation of tissue remodeling	4.116830e-7
GO:0051223	regulation of protein transport	4.369569e-7
GO:0001776	leukocyte homeostasis	4.810310e-7
GO:0032101	regulation of response to external stimulus	4.842653e-7
GO:0043066	negative regulation of apoptosis	5.224726e-7
GO:0051382	kinetochore assembly	5.422679e-7
GO:0060548	negative regulation of cell death	5.564309e-7
GO:2000026	regulation of multicellular organismal development	5.678368e-7
GO:0061041	regulation of wound healing	5.766075e-7
GO:0071034	CUT catabolic process	6.221180e-7
GO:0070489	T cell aggregation	6.221180e-7
GO:0045727	positive regulation of translation	7.062163e-7
GO:0014074	response to purine-containing compound	7.485428e-7
GO:0050818	regulation of coagulation	7.518890e-7
GO:0031000	response to caffeine	7.588771e-7
GO:0032755	positive regulation of interleukin-6 production	7.608965e-7
GO:0050709	negative regulation of protein secretion	7.639537e-7
GO:0032494	response to peptidoglycan	7.762132e-7
GO:0045779	negative regulation of bone resorption	8.219959e-7
GO:0007622	rhythmic behavior	8.219959e-7
GO:0043069	negative regulation of programmed cell death	8.290621e-7
GO:0045428	regulation of nitric oxide biosynthetic process	9.503591e-7
GO:0010722	regulation of ferrochelatase activity	9.580940e-7
GO:0050883	musculoskeletal movement, spinal reflex action	9.589726e-7
GO:0051383	kinetochore organization	1.307087e-6
GO:0051704	multi-organism process	1.322694e-6
GO:0007619	courtship behavior	1.375981e-6
GO:0045321	leukocyte activation	1.407093e-6
GO:0071347	cellular response to interleukin-1	1.427442e-6
GO:0001780	neutrophil homeostasis	1.458841e-6
GO:0045124	regulation of bone resorption	1.645007e-6
GO:0034508	centromere complex assembly	1.663094e-6
GO:0032675	regulation of interleukin-6 production	1.718553e-6
GO:0001819	positive regulation of cytokine production	1.774973e-6
GO:0002260	lymphocyte homeostasis	1.812019e-6
GO:0070555	response to interleukin-1	1.832543e-6
GO:0002688	regulation of leukocyte chemotaxis	1.932274e-6
GO:0018352	protein-pyridoxal-5-phosphate linkage	2.030715e-6
GO:0070102	interleukin-6-mediated signaling pathway	2.075160e-6
GO:0030193	regulation of blood coagulation	2.280707e-6
GO:0007566	embryo implantation	2.364092e-6
GO:0032680	regulation of tumor necrosis factor production	2.781678e-6
GO:0000236	mitotic prometaphase	2.879057e-6
GO:0009595	detection of biotic stimulus	2.975408e-6
GO:0035520	monoubiquitinated protein deubiquitination	3.064073e-6
GO:0070201	regulation of establishment of protein localization	3.202798e-6
GO:0002694	regulation of leukocyte activation	3.555108e-6
GO:0002690	positive regulation of leukocyte chemotaxis	3.645812e-6
GO:0071593	lymphocyte aggregation	3.856059e-6
GO:0000165	MAPKKK cascade	3.982353e-6
GO:0007252	I-kappaB phosphorylation	4.162175e-6
GO:0050865	regulation of cell activation	4.260412e-6
GO:0045079	negative regulation of chemokine biosynthetic process	4.271990e-6
GO:0046649	lymphocyte activation	4.537452e-6
GO:0051249	regulation of lymphocyte activation	4.649411e-6
GO:0032386	regulation of intracellular transport	4.824546e-6
GO:0002684	positive regulation of immune system process	5.382560e-6
GO:0035690	cellular response to drug	5.494659e-6
GO:0048520	positive regulation of behavior	5.899357e-6
GO:0035556	intracellular signal transduction	6.199605e-6
GO:0051241	negative regulation of multicellular organismal process	6.736662e-6
GO:0051971	positive regulation of transmission of nerve impulse	6.808885e-6
GO:0002262	myeloid cell homeostasis	6.941336e-6
GO:0048305	immunoglobulin secretion	7.393072e-6
GO:0043502	regulation of muscle adaptation	7.596359e-6
GO:0033160	positive regulation of protein import into nucleus, translocation	7.606531e-6
GO:0046822	regulation of nucleocytoplasmic transport	7.753712e-6
GO:0051701	interaction with host	8.049967e-6
GO:0070375	BMK cascade	8.084862e-6
GO:0010466	negative regulation of peptidase activity	8.139283e-6
GO:0071354	cellular response to interleukin-6	8.384777e-6
GO:0006916	anti-apoptosis	8.454358e-6
GO:0001817	regulation of cytokine production	8.553827e-6
GO:0071675	regulation of mononuclear cell migration	8.620983e-6
GO:0046545	development of primary female sexual characteristics	8.895327e-6
GO:0035093	spermatogenesis, exchange of chromosomal proteins	9.083457e-6
GO:0001782	B cell homeostasis	9.281239e-6
GO:0032388	positive regulation of intracellular transport	1.000012e-5
GO:0048511	rhythmic process	1.037429e-5
GO:0002376	immune system process	1.065757e-5
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.106646e-5
GO:0046651	lymphocyte proliferation	1.112904e-5
GO:0010751	negative regulation of nitric oxide mediated signal transduction	1.150797e-5
GO:0043652	engulfment of apoptotic cell	1.150797e-5
GO:0010754	negative regulation of cGMP-mediated signaling	1.150797e-5
GO:0002605	negative regulation of dendritic cell antigen processing and presentation	1.150797e-5
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.150797e-5
GO:0002548	monocyte chemotaxis	1.178864e-5
GO:0006511	ubiquitin-dependent protein catabolic process	1.187183e-5
GO:0034123	positive regulation of toll-like receptor signaling pathway	1.247919e-5
GO:0032880	regulation of protein localization	1.274843e-5
GO:0031296	B cell costimulation	1.324952e-5
GO:0042307	positive regulation of protein import into nucleus	1.329263e-5
GO:0042270	protection from natural killer cell mediated cytotoxicity	1.358757e-5
GO:0010955	negative regulation of protein processing	1.454433e-5
GO:0055117	regulation of cardiac muscle contraction	1.499456e-5
GO:0042035	regulation of cytokine biosynthetic process	1.516459e-5
GO:0046716	muscle cell homeostasis	1.521619e-5
GO:0019941	modification-dependent protein catabolic process	1.666617e-5
GO:0002687	positive regulation of leukocyte migration	1.703989e-5
GO:0052548	regulation of endopeptidase activity	1.795144e-5
GO:0030595	leukocyte chemotaxis	1.815446e-5
GO:0002685	regulation of leukocyte migration	1.880536e-5
GO:0031646	positive regulation of neurological system process	1.948234e-5
GO:0050877	neurological system process	1.985079e-5
GO:0050710	negative regulation of cytokine secretion	2.016505e-5
GO:0042110	T cell activation	2.033594e-5
GO:0051094	positive regulation of developmental process	2.081599e-5
GO:0010759	positive regulation of macrophage chemotaxis	2.133936e-5
GO:0032230	positive regulation of synaptic transmission, GABAergic	2.152357e-5
GO:0006915	apoptosis	2.180654e-5
GO:0032224	positive regulation of synaptic transmission, cholinergic	2.513340e-5
GO:0043170	macromolecule metabolic process	2.558885e-5
GO:0009057	macromolecule catabolic process	2.583476e-5
GO:0097035	regulation of membrane lipid distribution	2.689395e-5
GO:0032966	negative regulation of collagen biosynthetic process	2.855987e-5
GO:0006119	oxidative phosphorylation	2.913644e-5
GO:0043129	surfactant homeostasis	2.968552e-5
GO:0043154	negative regulation of caspase activity	2.973828e-5
GO:0070661	leukocyte proliferation	2.976755e-5
GO:0031349	positive regulation of defense response	3.016809e-5
GO:0016525	negative regulation of angiogenesis	3.031077e-5
GO:0046824	positive regulation of nucleocytoplasmic transport	3.095446e-5
GO:0014739	positive regulation of muscle hyperplasia	3.159498e-5
GO:0043632	modification-dependent macromolecule catabolic process	3.174572e-5
GO:0000296	spermine transport	3.175681e-5
GO:0002218	activation of innate immune response	3.281056e-5
GO:0033157	regulation of intracellular protein transport	3.304446e-5
GO:0048518	positive regulation of biological process	3.313405e-5
GO:0042534	regulation of tumor necrosis factor biosynthetic process	3.344089e-5
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	3.450804e-5
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	3.468418e-5
GO:0043201	response to leucine	3.476888e-5
GO:0006540	glutamate decarboxylation to succinate	3.487444e-5
GO:0010758	regulation of macrophage chemotaxis	3.487789e-5
GO:0045073	regulation of chemokine biosynthetic process	3.554610e-5
GO:0045137	development of primary sexual characteristics	3.564930e-5
GO:0050795	regulation of behavior	3.586527e-5
GO:0046660	female sex differentiation	3.893339e-5
GO:0010647	positive regulation of cell communication	3.990118e-5
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	4.073454e-5
GO:0032103	positive regulation of response to external stimulus	4.088970e-5
GO:0007009	plasma membrane organization	4.148344e-5
GO:2000112	regulation of cellular macromolecule biosynthetic process	4.174758e-5
GO:0023056	positive regulation of signaling	4.240159e-5
GO:0046834	lipid phosphorylation	4.269896e-5
GO:0030334	regulation of cell migration	4.351547e-5
GO:0002252	immune effector process	4.379018e-5
GO:0044265	cellular macromolecule catabolic process	4.397167e-5
GO:0032943	mononuclear cell proliferation	4.485019e-5
GO:0051932	synaptic transmission, GABAergic	4.560850e-5
GO:0051093	negative regulation of developmental process	4.712026e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	4.720209e-5
GO:0002675	positive regulation of acute inflammatory response	4.874689e-5
GO:0042306	regulation of protein import into nucleus	4.903544e-5
GO:0021869	forebrain ventricular zone progenitor cell division	4.999589e-5
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	5.009104e-5
GO:0010468	regulation of gene expression	5.053236e-5
GO:0048584	positive regulation of response to stimulus	5.059477e-5
GO:0046854	phosphatidylinositol phosphorylation	5.184370e-5
GO:0009065	glutamine family amino acid catabolic process	5.343625e-5
GO:0009611	response to wounding	5.354440e-5
GO:0072285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	5.383775e-5
GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway	5.383775e-5
GO:0007371	ventral midline determination	5.383775e-5
GO:0060248	detection of cell density by contact stimulus involved in contact inhibition	5.383775e-5
GO:0010574	regulation of vascular endothelial growth factor production	5.417950e-5
GO:0051603	proteolysis involved in cellular protein catabolic process	5.510787e-5
GO:0050884	neuromuscular process controlling posture	5.769828e-5
GO:0010766	negative regulation of sodium ion transport	5.769828e-5
GO:0060255	regulation of macromolecule metabolic process	5.865664e-5
GO:0033689	negative regulation of osteoblast proliferation	5.878483e-5
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	6.138585e-5
GO:0007270	neuron-neuron synaptic transmission	6.213780e-5
GO:0034764	positive regulation of transmembrane transport	6.321506e-5
GO:0090316	positive regulation of intracellular protein transport	6.334452e-5
GO:2000191	regulation of fatty acid transport	6.352660e-5
GO:0048634	regulation of muscle organ development	6.465645e-5
GO:0021795	cerebral cortex cell migration	6.510341e-5
GO:0012501	programmed cell death	6.668125e-5
GO:0007623	circadian rhythm	6.889305e-5
GO:0016049	cell growth	6.922347e-5
GO:0048732	gland development	6.926775e-5
GO:0044257	cellular protein catabolic process	7.060173e-5
GO:0002634	regulation of germinal center formation	7.383434e-5
GO:0008585	female gonad development	7.432995e-5
GO:0046903	secretion	7.444744e-5
GO:0030163	protein catabolic process	7.461304e-5
GO:0009266	response to temperature stimulus	7.585227e-5
GO:0060326	cell chemotaxis	8.017103e-5
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	8.434644e-5
GO:0048522	positive regulation of cellular process	8.592198e-5
GO:0019222	regulation of metabolic process	8.739281e-5
GO:0006911	phagocytosis, engulfment	8.792345e-5
GO:0032845	negative regulation of homeostatic process	8.939932e-5
GO:0070995	NADPH oxidation	9.069722e-5
GO:0019230	proprioception	9.069722e-5
GO:0010941	regulation of cell death	9.089884e-5
GO:0071843	cellular component biogenesis at cellular level	9.107045e-5
GO:0060249	anatomical structure homeostasis	9.184821e-5
GO:0070647	protein modification by small protein conjugation or removal	9.302391e-5
GO:0031326	regulation of cellular biosynthetic process	9.303534e-5
GO:0042113	B cell activation	9.607149e-5
GO:0071504	cellular response to heparin	9.640378e-5
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	9.666126e-5
GO:0071622	regulation of granulocyte chemotaxis	1.001726e-4
GO:0050793	regulation of developmental process	1.005039e-4
GO:0051346	negative regulation of hydrolase activity	1.016512e-4
GO:0009581	detection of external stimulus	1.041869e-4
GO:0034110	regulation of homotypic cell-cell adhesion	1.052538e-4
GO:0080090	regulation of primary metabolic process	1.054214e-4
GO:0008406	gonad development	1.055847e-4
GO:0051224	negative regulation of protein transport	1.069837e-4
GO:0051180	vitamin transport	1.072319e-4
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	1.092283e-4
GO:0044003	modification by symbiont of host morphology or physiology	1.106091e-4
GO:0001561	fatty acid alpha-oxidation	1.107782e-4
GO:0046184	aldehyde biosynthetic process	1.120853e-4
GO:0090331	negative regulation of platelet aggregation	1.128721e-4
GO:0061110	dense core granule biogenesis	1.128721e-4
GO:0042628	mating plug formation	1.128721e-4
GO:0061108	seminal vesicle epithelium development	1.128721e-4
GO:0042493	response to drug	1.150398e-4
GO:0046883	regulation of hormone secretion	1.159504e-4
GO:0045667	regulation of osteoblast differentiation	1.173628e-4
GO:0050708	regulation of protein secretion	1.202882e-4
GO:0061039	ovum-producing ovary development	1.206230e-4
GO:0046620	regulation of organ growth	1.212611e-4
GO:0070613	regulation of protein processing	1.273634e-4
GO:0046485	ether lipid metabolic process	1.281264e-4
GO:0046618	drug export	1.288441e-4
GO:0009889	regulation of biosynthetic process	1.312605e-4
GO:0009617	response to bacterium	1.339312e-4
GO:0010038	response to metal ion	1.359592e-4
GO:0016226	iron-sulfur cluster assembly	1.366966e-4
GO:0010561	negative regulation of glycoprotein biosynthetic process	1.368155e-4
GO:0031323	regulation of cellular metabolic process	1.371390e-4
GO:0022602	ovulation cycle process	1.391570e-4
GO:0060284	regulation of cell development	1.394261e-4
GO:0009607	response to biotic stimulus	1.396381e-4
GO:0034139	regulation of toll-like receptor 3 signaling pathway	1.397144e-4
GO:0010713	negative regulation of collagen metabolic process	1.398987e-4
GO:0002253	activation of immune response	1.409825e-4
GO:0046546	development of primary male sexual characteristics	1.435250e-4
GO:0002251	organ or tissue specific immune response	1.458566e-4
GO:0042036	negative regulation of cytokine biosynthetic process	1.468431e-4
GO:0006417	regulation of translation	1.477614e-4
GO:0034205	beta-amyloid formation	1.494190e-4
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	1.496990e-4
GO:0052572	response to host immune response	1.531295e-4
GO:0051349	positive regulation of lyase activity	1.535834e-4
GO:0007113	endomitotic cell cycle	1.540400e-4
GO:0048148	behavioral response to cocaine	1.561549e-4
GO:0045597	positive regulation of cell differentiation	1.577526e-4
GO:0071503	response to heparin	1.607982e-4
GO:0050890	cognition	1.654035e-4
GO:0010556	regulation of macromolecule biosynthetic process	1.692195e-4
GO:0051222	positive regulation of protein transport	1.705781e-4
GO:0010033	response to organic substance	1.709347e-4
GO:0060341	regulation of cellular localization	1.720856e-4
GO:0051607	defense response to virus	1.738152e-4
GO:0034339	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.753699e-4
GO:0042221	response to chemical stimulus	1.847821e-4
GO:0050867	positive regulation of cell activation	1.861585e-4
GO:0034103	regulation of tissue remodeling	1.868585e-4
GO:0009886	post-embryonic morphogenesis	1.909981e-4
GO:0009891	positive regulation of biosynthetic process	1.914774e-4
GO:0050778	positive regulation of immune response	1.915449e-4
GO:0072678	T cell migration	1.919546e-4
GO:0070536	protein K63-linked deubiquitination	1.978790e-4
GO:0044260	cellular macromolecule metabolic process	1.991204e-4
GO:0009056	catabolic process	2.010538e-4
GO:0052547	regulation of peptidase activity	2.019566e-4
GO:0032308	positive regulation of prostaglandin secretion	2.030931e-4
GO:0070925	organelle assembly	2.034744e-4
GO:0002696	positive regulation of leukocyte activation	2.079871e-4
GO:0032026	response to magnesium ion	2.081388e-4
GO:0003127	detection of nodal flow	2.086525e-4
GO:0045721	negative regulation of gluconeogenesis	2.170738e-4
GO:0019228	regulation of action potential in neuron	2.174264e-4
GO:0032735	positive regulation of interleukin-12 production	2.190420e-4
GO:0042698	ovulation cycle	2.219831e-4
GO:0002682	regulation of immune system process	2.247764e-4
GO:0008584	male gonad development	2.274306e-4
GO:0002221	pattern recognition receptor signaling pathway	2.313303e-4
GO:0008283	cell proliferation	2.316941e-4
GO:0051171	regulation of nitrogen compound metabolic process	2.326641e-4
GO:0042908	xenobiotic transport	2.349474e-4
GO:0043331	response to dsRNA	2.369412e-4
GO:0010823	negative regulation of mitochondrion organization	2.369779e-4
GO:0022613	ribonucleoprotein complex biogenesis	2.400917e-4
GO:0002446	neutrophil mediated immunity	2.441195e-4
GO:0002832	negative regulation of response to biotic stimulus	2.481752e-4
GO:0010763	positive regulation of fibroblast migration	2.581317e-4
GO:0045089	positive regulation of innate immune response	2.603159e-4
GO:0051716	cellular response to stimulus	2.632949e-4
GO:0035249	synaptic transmission, glutamatergic	2.659506e-4
GO:0042981	regulation of apoptosis	2.676790e-4
GO:0006499	N-terminal protein myristoylation	2.688318e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	2.707864e-4
GO:0051252	regulation of RNA metabolic process	2.733369e-4
GO:0045884	regulation of survival gene product expression	2.766650e-4
GO:0002237	response to molecule of bacterial origin	2.801864e-4
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	2.803396e-4
GO:0043277	apoptotic cell clearance	2.823653e-4
GO:0019087	transformation of host cell by virus	2.824894e-4
GO:0010614	negative regulation of cardiac muscle hypertrophy	2.842747e-4
GO:0046685	response to arsenic-containing substance	2.868164e-4
GO:0051960	regulation of nervous system development	2.898481e-4
GO:0043067	regulation of programmed cell death	2.912568e-4
GO:0043537	negative regulation of blood vessel endothelial cell migration	2.921013e-4
GO:0002521	leukocyte differentiation	2.934476e-4
GO:0071872	cellular response to epinephrine stimulus	3.006259e-4
GO:0051918	negative regulation of fibrinolysis	3.065295e-4
GO:0071243	cellular response to arsenic-containing substance	3.086724e-4
GO:0008050	female courtship behavior	3.180665e-4
GO:0032496	response to lipopolysaccharide	3.187570e-4
GO:0009249	protein lipoylation	3.252488e-4
GO:0002700	regulation of production of molecular mediator of immune response	3.293113e-4
GO:0030259	lipid glycosylation	3.302799e-4
GO:0006554	lysine catabolic process	3.417411e-4
GO:0008049	male courtship behavior	3.428301e-4
GO:0071404	cellular response to low-density lipoprotein particle stimulus	3.430757e-4
GO:0000085	G2 phase of mitotic cell cycle	3.445066e-4
GO:0016075	rRNA catabolic process	3.537497e-4
GO:0051592	response to calcium ion	3.540031e-4
GO:0016567	protein ubiquitination	3.599201e-4
GO:0050707	regulation of cytokine secretion	3.662948e-4
GO:0006235	dTTP biosynthetic process	3.670757e-4
GO:0034122	negative regulation of toll-like receptor signaling pathway	3.674093e-4
GO:0050482	arachidonic acid secretion	3.705011e-4
GO:0031328	positive regulation of cellular biosynthetic process	3.773282e-4
GO:0016579	protein deubiquitination	3.774192e-4
GO:0034346	positive regulation of type III interferon production	3.807405e-4
GO:0042440	pigment metabolic process	3.821126e-4
GO:0072592	oxygen metabolic process	3.894106e-4
GO:0022414	reproductive process	3.901309e-4
GO:0030098	lymphocyte differentiation	3.988261e-4
GO:0032663	regulation of interleukin-2 production	4.146586e-4
GO:0051707	response to other organism	4.163536e-4
GO:0021547	midbrain-hindbrain boundary initiation	4.170488e-4
GO:0021501	prechordal plate formation	4.170488e-4
GO:0000003	reproduction	4.188191e-4
GO:0045059	positive thymic T cell selection	4.312559e-4
GO:0051282	regulation of sequestering of calcium ion	4.320461e-4
GO:0050921	positive regulation of chemotaxis	4.333453e-4
GO:2000145	regulation of cell motility	4.390239e-4
GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process	4.454329e-4
GO:0034698	response to gonadotropin stimulus	4.645672e-4
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway	4.665817e-4
GO:0071333	cellular response to glucose stimulus	4.679792e-4
GO:0051353	positive regulation of oxidoreductase activity	4.680113e-4
GO:0048807	female genitalia morphogenesis	4.706767e-4
GO:0007611	learning or memory	4.740474e-4
GO:0021918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	4.769147e-4
GO:0021905	forebrain-midbrain boundary formation	4.769147e-4
GO:0003322	pancreatic A cell development	4.769147e-4
GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	4.769147e-4
GO:0051209	release of sequestered calcium ion into cytosol	4.778102e-4
GO:0002637	regulation of immunoglobulin production	4.800794e-4
GO:0008152	metabolic process	4.811522e-4
GO:0007243	intracellular protein kinase cascade	4.859349e-4
GO:0034135	regulation of toll-like receptor 2 signaling pathway	5.005622e-4
GO:0060044	negative regulation of cardiac muscle cell proliferation	5.012345e-4
GO:0040014	regulation of multicellular organism growth	5.051127e-4
GO:0035239	tube morphogenesis	5.115214e-4
GO:0071636	positive regulation of transforming growth factor beta production	5.215707e-4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	5.351920e-4
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	5.353007e-4
GO:0022618	ribonucleoprotein complex assembly	5.363296e-4
GO:0048583	regulation of response to stimulus	5.413202e-4
GO:0034633	retinol transport	5.422405e-4
GO:0001834	trophectodermal cell proliferation	5.422405e-4
GO:0002758	innate immune response-activating signal transduction	5.437261e-4
GO:0045732	positive regulation of protein catabolic process	5.458545e-4
GO:0009068	aspartate family amino acid catabolic process	5.476375e-4
GO:0032474	otolith morphogenesis	5.679927e-4
GO:0010611	regulation of cardiac muscle hypertrophy	5.699760e-4
GO:0045085	negative regulation of interleukin-2 biosynthetic process	5.706583e-4
GO:0030970	retrograde protein transport, ER to cytosol	5.706583e-4
GO:0043368	positive T cell selection	5.731699e-4
GO:0032410	negative regulation of transporter activity	5.871727e-4
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	5.921426e-4
GO:0006355	regulation of transcription, DNA-dependent	6.055003e-4
GO:0014741	negative regulation of muscle hypertrophy	6.100093e-4
GO:0030278	regulation of ossification	6.141184e-4
GO:0051047	positive regulation of secretion	6.159860e-4
GO:0043217	myelin maintenance	6.163009e-4
GO:0046661	male sex differentiation	6.288217e-4
GO:0033555	multicellular organismal response to stress	6.312996e-4
GO:0046888	negative regulation of hormone secretion	6.435794e-4
GO:0019219	regulation of nucleobase-containing compound metabolic process	6.457686e-4
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	6.688733e-4
GO:0007165	signal transduction	6.766075e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	6.818313e-4
GO:0031644	regulation of neurological system process	6.829033e-4
GO:0071402	cellular response to lipoprotein particle stimulus	6.843857e-4
GO:2000116	regulation of cysteine-type endopeptidase activity	6.868261e-4
GO:0002683	negative regulation of immune system process	6.879399e-4
GO:0043279	response to alkaloid	6.912373e-4
GO:0045087	innate immune response	6.916986e-4
GO:0002286	T cell activation involved in immune response	6.998522e-4
GO:0016265	death	7.093512e-4
GO:0051917	regulation of fibrinolysis	7.224898e-4
GO:0035413	positive regulation of catenin import into nucleus	7.227841e-4
GO:0009200	deoxyribonucleoside triphosphate metabolic process	7.434195e-4
GO:0051969	regulation of transmission of nerve impulse	7.638343e-4
GO:0007059	chromosome segregation	7.642944e-4
GO:0002544	chronic inflammatory response	7.648266e-4
GO:0010596	negative regulation of endothelial cell migration	7.681582e-4
GO:0002604	regulation of dendritic cell antigen processing and presentation	7.686977e-4
GO:0051310	metaphase plate congression	7.767829e-4
GO:0048513	organ development	7.826201e-4
GO:0040012	regulation of locomotion	7.883591e-4
GO:0040040	thermosensory behavior	8.034444e-4
GO:0034112	positive regulation of homotypic cell-cell adhesion	8.034444e-4
GO:0014743	regulation of muscle hypertrophy	8.055308e-4
GO:0042391	regulation of membrane potential	8.095744e-4
GO:0030217	T cell differentiation	8.123022e-4
GO:0048265	response to pain	8.130383e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	8.207795e-4
GO:0071715	icosanoid transport	8.255512e-4
GO:0009967	positive regulation of signal transduction	8.467899e-4
GO:0007589	body fluid secretion	8.473492e-4
GO:0010467	gene expression	8.780333e-4
GO:0019242	methylglyoxal biosynthetic process	8.812610e-4
GO:0030162	regulation of proteolysis	8.816094e-4
GO:0060152	microtubule-based peroxisome localization	8.898041e-4
GO:0048608	reproductive structure development	8.952982e-4
GO:0060043	regulation of cardiac muscle cell proliferation	9.011854e-4
GO:0060157	urinary bladder development	9.060154e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	9.152004e-4
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	9.235524e-4
GO:0042100	B cell proliferation	9.416537e-4
GO:0071216	cellular response to biotic stimulus	9.422258e-4
GO:0032446	protein modification by small protein conjugation	9.475053e-4
GO:0071460	cellular response to cell-matrix adhesion	9.600738e-4
GO:0048243	norepinephrine secretion	9.643104e-4
GO:0003140	determination of left/right asymmetry in lateral mesoderm	9.711231e-4
GO:0007548	sex differentiation	9.776196e-4
GO:0008219	cell death	9.806289e-4
GO:0071826	ribonucleoprotein complex subunit organization	9.841109e-4
GO:0050830	defense response to Gram-positive bacterium	9.849733e-4
GO:0051895	negative regulation of focal adhesion assembly	9.862955e-4
GO:0050920	regulation of chemotaxis	9.866788e-4
GO:0051051	negative regulation of transport	1.006715e-3
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	1.018065e-3
GO:0030258	lipid modification	1.021339e-3
GO:0006950	response to stress	1.029465e-3
GO:0019098	reproductive behavior	1.036285e-3
GO:0046148	pigment biosynthetic process	1.049561e-3
GO:0050790	regulation of catalytic activity	1.075614e-3
GO:0042489	negative regulation of odontogenesis of dentine-containing tooth	1.078047e-3
GO:0031342	negative regulation of cell killing	1.083299e-3
GO:0034645	cellular macromolecule biosynthetic process	1.084755e-3
GO:0035092	sperm chromatin condensation	1.086763e-3
GO:0016477	cell migration	1.099976e-3
GO:0046677	response to antibiotic	1.102734e-3
GO:0046208	spermine catabolic process	1.103913e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	5.015268e-25
GO:0006400	tRNA modification	3.835618e-20
GO:0030488	tRNA methylation	9.494742e-20
GO:0001510	RNA methylation	1.359064e-13
GO:0008033	tRNA processing	2.411205e-13
GO:0009451	RNA modification	4.534992e-12
GO:0048515	spermatid differentiation	7.289033e-12
GO:0007286	spermatid development	3.544791e-10
GO:0055119	relaxation of cardiac muscle	7.934263e-9
GO:0034470	ncRNA processing	1.332099e-8
GO:0046709	IDP catabolic process	1.418331e-8
GO:0046032	ADP catabolic process	1.418331e-8
GO:0034392	negative regulation of smooth muscle cell apoptosis	2.144375e-8
GO:0006581	acetylcholine catabolic process	2.246230e-8
GO:0014904	myotube cell development	5.294943e-8
GO:0006399	tRNA metabolic process	5.557829e-8
GO:0007271	synaptic transmission, cholinergic	8.685295e-8
GO:0060282	positive regulation of oocyte development	8.795969e-8
GO:0060281	regulation of oocyte development	8.795969e-8
GO:0050819	negative regulation of coagulation	9.036183e-8
GO:0009566	fertilization	1.057591e-7
GO:0055118	negative regulation of cardiac muscle contraction	1.595589e-7
GO:0043931	ossification involved in bone maturation	1.595589e-7
GO:0008291	acetylcholine metabolic process	1.679309e-7
GO:0048469	cell maturation	1.721911e-7
GO:0006835	dicarboxylic acid transport	1.966137e-7
GO:0048146	positive regulation of fibroblast proliferation	2.404472e-7
GO:0021700	developmental maturation	2.649516e-7
GO:0018105	peptidyl-serine phosphorylation	3.225081e-7
GO:0030195	negative regulation of blood coagulation	3.378707e-7
GO:0070977	bone maturation	4.763933e-7
GO:0002676	regulation of chronic inflammatory response	4.946818e-7
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	7.827508e-7
GO:0002678	positive regulation of chronic inflammatory response	8.450942e-7
GO:0060741	prostate gland stromal morphogenesis	8.716785e-7
GO:0045212	neurotransmitter receptor biosynthetic process	1.171275e-6
GO:0035630	bone mineralization involved in bone maturation	1.171275e-6
GO:0032878	regulation of establishment or maintenance of cell polarity	1.386940e-6
GO:0043129	surfactant homeostasis	1.489489e-6
GO:0048610	cellular process involved in reproduction	2.301386e-6
GO:0090201	negative regulation of release of cytochrome c from mitochondria	2.361219e-6
GO:0070375	BMK cascade	3.682042e-6
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	3.856833e-6
GO:0010823	negative regulation of mitochondrion organization	3.913853e-6
GO:0070723	response to cholesterol	5.148207e-6
GO:0060736	prostate gland growth	6.050519e-6
GO:0006214	thymidine catabolic process	6.068797e-6
GO:0045213	neurotransmitter receptor metabolic process	6.949493e-6
GO:0040014	regulation of multicellular organism growth	7.463128e-6
GO:0048661	positive regulation of smooth muscle cell proliferation	7.640850e-6
GO:0042772	DNA damage response, signal transduction resulting in transcription	8.337190e-6
GO:0046326	positive regulation of glucose import	8.506410e-6
GO:0051932	synaptic transmission, GABAergic	8.695283e-6
GO:0051224	negative regulation of protein transport	8.949058e-6
GO:0015939	pantothenate metabolic process	9.036237e-6
GO:0010656	negative regulation of muscle cell apoptosis	9.546081e-6
GO:0031558	induction of apoptosis in response to chemical stimulus	1.016802e-5
GO:0010564	regulation of cell cycle process	1.017716e-5
GO:0000492	box C/D snoRNP assembly	1.028007e-5
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	1.060519e-5
GO:0051726	regulation of cell cycle	1.070949e-5
GO:0060740	prostate gland epithelium morphogenesis	1.081161e-5
GO:0003207	cardiac chamber formation	1.198370e-5
GO:0060512	prostate gland morphogenesis	1.284451e-5
GO:0043069	negative regulation of programmed cell death	1.288573e-5
GO:0001974	blood vessel remodeling	1.309993e-5
GO:0048145	regulation of fibroblast proliferation	1.345703e-5
GO:0003211	cardiac ventricle formation	1.618812e-5
GO:0006212	uracil catabolic process	1.665248e-5
GO:0060548	negative regulation of cell death	1.762693e-5
GO:0051534	negative regulation of NFAT protein import into nucleus	1.981925e-5
GO:0046826	negative regulation of protein export from nucleus	2.047517e-5
GO:0031119	tRNA pseudouridine synthesis	2.300973e-5
GO:0046069	cGMP catabolic process	2.387855e-5
GO:0010613	positive regulation of cardiac muscle hypertrophy	2.626753e-5
GO:0009181	purine ribonucleoside diphosphate catabolic process	2.630976e-5
GO:0031397	negative regulation of protein ubiquitination	2.731225e-5
GO:0046373	L-arabinose metabolic process	3.152888e-5
GO:0042311	vasodilation	3.374824e-5
GO:0035234	germ cell programmed cell death	3.387891e-5
GO:0001780	neutrophil homeostasis	3.404221e-5
GO:0006071	glycerol metabolic process	3.432385e-5
GO:0034660	ncRNA metabolic process	3.517815e-5
GO:0007281	germ cell development	3.519054e-5
GO:0007214	gamma-aminobutyric acid signaling pathway	3.661776e-5
GO:0014834	satellite cell maintenance involved in skeletal muscle regeneration	3.871119e-5
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	3.911787e-5
GO:0046031	ADP metabolic process	4.044479e-5
GO:0009446	putrescine biosynthetic process	4.158841e-5
GO:0006493	protein O-linked glycosylation	4.291235e-5
GO:0043066	negative regulation of apoptosis	4.476635e-5
GO:0060509	Type I pneumocyte differentiation	4.508324e-5
GO:0051450	myoblast proliferation	4.513886e-5
GO:0010828	positive regulation of glucose transport	4.612396e-5
GO:0032101	regulation of response to external stimulus	4.950792e-5
GO:0014743	regulation of muscle hypertrophy	5.135586e-5
GO:0045226	extracellular polysaccharide biosynthetic process	5.262775e-5
GO:0006507	GPI anchor release	5.262775e-5
GO:0031348	negative regulation of defense response	5.464484e-5
GO:0002320	lymphoid progenitor cell differentiation	5.611983e-5
GO:0003215	cardiac right ventricle morphogenesis	6.409915e-5
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	6.584702e-5
GO:0002328	pro-B cell differentiation	6.677716e-5
GO:0031570	DNA integrity checkpoint	6.762963e-5
GO:0000077	DNA damage checkpoint	6.785044e-5
GO:2000241	regulation of reproductive process	6.818051e-5
GO:0060749	mammary gland alveolus development	7.113167e-5
GO:0006222	UMP biosynthetic process	7.285500e-5
GO:0060766	negative regulation of androgen receptor signaling pathway	8.287447e-5
GO:0010941	regulation of cell death	8.297844e-5
GO:0008216	spermidine metabolic process	8.366705e-5
GO:0034391	regulation of smooth muscle cell apoptosis	8.978102e-5
GO:0045786	negative regulation of cell cycle	9.117304e-5
GO:0060525	prostate glandular acinus development	9.686412e-5
GO:0014066	regulation of phosphatidylinositol 3-kinase cascade	1.030814e-4
GO:0071156	regulation of cell cycle arrest	1.079558e-4
GO:0060442	branching involved in prostate gland morphogenesis	1.085067e-4
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1.096591e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.113698e-4
GO:0006210	thymine catabolic process	1.147860e-4
GO:0019400	alditol metabolic process	1.210307e-4
GO:0014911	positive regulation of smooth muscle cell migration	1.220721e-4
GO:0019695	choline metabolic process	1.235576e-4
GO:0018209	peptidyl-serine modification	1.238814e-4
GO:0015826	threonine transport	1.276992e-4
GO:0034589	hydroxyproline transport	1.276992e-4
GO:0043067	regulation of programmed cell death	1.287093e-4
GO:0001662	behavioral fear response	1.298396e-4
GO:0043501	skeletal muscle adaptation	1.307397e-4
GO:0043620	regulation of DNA-dependent transcription in response to stress	1.309540e-4
GO:0061138	morphogenesis of a branching epithelium	1.358657e-4
GO:0042596	fear response	1.398032e-4
GO:0046823	negative regulation of nucleocytoplasmic transport	1.411701e-4
GO:0048844	artery morphogenesis	1.433824e-4
GO:0002209	behavioral defense response	1.469448e-4
GO:0090317	negative regulation of intracellular protein transport	1.538266e-4
GO:0042135	neurotransmitter catabolic process	1.560288e-4
GO:0046425	regulation of JAK-STAT cascade	1.727987e-4
GO:0043503	skeletal muscle fiber adaptation	1.798563e-4
GO:0032060	bleb assembly	1.798563e-4
GO:0045839	negative regulation of mitosis	1.847232e-4
GO:0010660	regulation of muscle cell apoptosis	1.865648e-4
GO:0035909	aorta morphogenesis	1.865648e-4
GO:0032514	positive regulation of protein phosphatase type 2B activity	1.882702e-4
GO:0009134	nucleoside diphosphate catabolic process	1.893534e-4
GO:0001763	morphogenesis of a branching structure	1.935156e-4
GO:0010611	regulation of cardiac muscle hypertrophy	2.070138e-4
GO:0030850	prostate gland development	2.111494e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	2.116269e-4
GO:0097116	gephyrin clustering	2.153892e-4
GO:0009452	RNA capping	2.161873e-4
GO:0071425	hemopoietic stem cell proliferation	2.186060e-4
GO:0030879	mammary gland development	2.354811e-4
GO:0003006	developmental process involved in reproduction	2.382099e-4
GO:0015711	organic anion transport	2.385660e-4
GO:0071397	cellular response to cholesterol	2.387884e-4
GO:0007614	short-term memory	2.435005e-4
GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation	2.463627e-4
GO:0035910	ascending aorta morphogenesis	2.463627e-4
GO:0002244	hemopoietic progenitor cell differentiation	2.499840e-4
GO:0010948	negative regulation of cell cycle process	2.684096e-4
GO:0046587	positive regulation of calcium-dependent cell-cell adhesion	2.707409e-4
GO:0010747	positive regulation of plasma membrane long-chain fatty acid transport	2.707409e-4
GO:0048814	regulation of dendrite morphogenesis	2.720171e-4
GO:0006974	response to DNA damage stimulus	2.793758e-4
GO:0022616	DNA strand elongation	2.801711e-4
GO:0045821	positive regulation of glycolysis	2.810642e-4
GO:0032102	negative regulation of response to external stimulus	2.868137e-4
GO:0042981	regulation of apoptosis	2.882511e-4
GO:0007263	nitric oxide mediated signal transduction	2.932641e-4
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	3.074930e-4
GO:0032801	receptor catabolic process	3.198507e-4
GO:0060134	prepulse inhibition	3.269250e-4
GO:0010544	negative regulation of platelet activation	3.643407e-4
GO:0000075	cell cycle checkpoint	3.684149e-4
GO:0060563	neuroepithelial cell differentiation	4.055658e-4
GO:0032868	response to insulin stimulus	4.490695e-4
GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein	4.545088e-4
GO:0042402	cellular biogenic amine catabolic process	4.556831e-4
GO:0008016	regulation of heart contraction	4.587850e-4
GO:0019089	transmission of virus	4.703335e-4
GO:0044111	development involved in symbiotic interaction	4.703335e-4
GO:0015825	L-serine transport	4.703335e-4
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	4.703335e-4
GO:0070201	regulation of establishment of protein localization	4.783636e-4
GO:0014888	striated muscle adaptation	4.906946e-4
GO:0033144	negative regulation of steroid hormone receptor signaling pathway	4.941171e-4
GO:0042350	GDP-L-fucose biosynthetic process	5.120793e-4
GO:0015811	L-cystine transport	5.120793e-4
GO:0033136	serine phosphorylation of STAT3 protein	5.120793e-4
GO:0003183	mitral valve morphogenesis	5.141585e-4
GO:0014896	muscle hypertrophy	5.371854e-4
GO:0003230	cardiac atrium development	5.384664e-4
GO:0048754	branching morphogenesis of a tube	5.390660e-4
GO:0042501	serine phosphorylation of STAT protein	5.794117e-4
GO:0090273	regulation of somatostatin secretion	5.893023e-4
GO:0046121	deoxyribonucleoside catabolic process	5.978456e-4
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.978456e-4
GO:2000425	regulation of apoptotic cell clearance	6.092247e-4
GO:0021801	cerebral cortex radial glia guided migration	6.133119e-4
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	6.133119e-4
GO:0010466	negative regulation of peptidase activity	6.360580e-4
GO:0031400	negative regulation of protein modification process	6.624833e-4
GO:0006396	RNA processing	6.742890e-4
GO:0034224	cellular response to zinc ion starvation	6.840644e-4
GO:0019532	oxalate transport	6.840644e-4
GO:0002683	negative regulation of immune system process	7.161319e-4
GO:0050765	negative regulation of phagocytosis	7.410380e-4
GO:0032800	receptor biosynthetic process	7.583482e-4
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	7.659662e-4
GO:2000243	positive regulation of reproductive process	7.704787e-4
GO:0090075	relaxation of muscle	7.763532e-4
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	7.863604e-4
GO:0051223	regulation of protein transport	7.934531e-4
GO:2000826	regulation of heart morphogenesis	8.033711e-4
GO:0000380	alternative nuclear mRNA splicing, via spliceosome	8.080868e-4
GO:0031342	negative regulation of cell killing	8.157594e-4
GO:0006370	mRNA capping	8.499707e-4
GO:0048478	replication fork protection	8.782590e-4
GO:0014057	positive regulation of acetylcholine secretion	8.782590e-4
GO:0060840	artery development	8.806480e-4
GO:0031442	positive regulation of mRNA 3'-end processing	8.860523e-4
GO:0003283	atrial septum development	8.965932e-4
GO:0003357	noradrenergic neuron differentiation	9.130938e-4
GO:0050818	regulation of coagulation	9.802669e-4
GO:0035588	G-protein coupled purinergic receptor signaling pathway	9.841971e-4
GO:0001541	ovarian follicle development	9.854379e-4
GO:0006916	anti-apoptosis	9.995532e-4
GO:0022612	gland morphogenesis	9.996357e-4
GO:0071695	anatomical structure maturation	1.008757e-3
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	1.029568e-3
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.032096e-3
GO:0097118	neuroligin clustering	1.044227e-3
GO:0009896	positive regulation of catabolic process	1.050849e-3
GO:0019227	neuronal action potential propagation	1.051675e-3
GO:0035108	limb morphogenesis	1.078527e-3
GO:0048485	sympathetic nervous system development	1.092018e-3
GO:0050679	positive regulation of epithelial cell proliferation	1.117697e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	1.144131e-3
GO:0001887	selenium compound metabolic process	1.150701e-3
GO:0043526	neuroprotection	1.155124e-3
GO:0061325	cell proliferation involved in outflow tract morphogenesis	1.161420e-3
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	1.161420e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	1.176489e-3
GO:0072395	signal transduction involved in cell cycle checkpoint	1.218092e-3
GO:0022610	biological adhesion	1.227645e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	1.243613e-3
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	1.243613e-3
GO:0035883	enteroendocrine cell differentiation	1.243613e-3
GO:0043403	skeletal muscle tissue regeneration	1.269457e-3
GO:0072329	monocarboxylic acid catabolic process	1.276911e-3
GO:0002698	negative regulation of immune effector process	1.282729e-3
GO:0007155	cell adhesion	1.296161e-3
GO:0007399	nervous system development	1.327044e-3
GO:0050728	negative regulation of inflammatory response	1.337994e-3
GO:0000723	telomere maintenance	1.349661e-3
GO:2000602	regulation of interphase of mitotic cell cycle	1.354669e-3
GO:0060039	pericardium development	1.355961e-3
GO:0000082	G1/S transition of mitotic cell cycle	1.359061e-3
GO:0051054	positive regulation of DNA metabolic process	1.367674e-3
GO:0051262	protein tetramerization	1.380735e-3
GO:0042770	signal transduction in response to DNA damage	1.386413e-3
GO:0008295	spermidine biosynthetic process	1.400810e-3
GO:0003209	cardiac atrium morphogenesis	1.420220e-3
GO:0030193	regulation of blood coagulation	1.425492e-3
GO:0007405	neuroblast proliferation	1.425892e-3
GO:0031018	endocrine pancreas development	1.451320e-3
GO:0031860	telomeric 3' overhang formation	1.474027e-3
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.474027e-3
GO:0001971	negative regulation of activation of membrane attack complex	1.474027e-3
GO:0006432	phenylalanyl-tRNA aminoacylation	1.474548e-3
GO:0046777	protein autophosphorylation	1.480443e-3
GO:0072422	signal transduction involved in DNA damage checkpoint	1.480538e-3
GO:0015908	fatty acid transport	1.561814e-3
GO:0061041	regulation of wound healing	1.600174e-3
GO:0035904	aorta development	1.618467e-3
GO:0046579	positive regulation of Ras protein signal transduction	1.618467e-3
GO:0043112	receptor metabolic process	1.658755e-3
GO:0018343	protein farnesylation	1.683339e-3
GO:0043500	muscle adaptation	1.684406e-3
GO:0010867	positive regulation of triglyceride biosynthetic process	1.691097e-3
GO:0032329	serine transport	1.699752e-3
GO:0019673	GDP-mannose metabolic process	1.699752e-3
GO:0015808	L-alanine transport	1.699752e-3
GO:0051532	regulation of NFAT protein import into nucleus	1.715447e-3
GO:0009185	ribonucleoside diphosphate metabolic process	1.723145e-3
GO:0071773	cellular response to BMP stimulus	1.796653e-3
GO:0002076	osteoblast development	1.801093e-3
GO:0019233	sensory perception of pain	1.819103e-3
GO:0019395	fatty acid oxidation	1.825993e-3
GO:0035584	calcium-mediated signaling using intracellular calcium source	1.851719e-3
GO:0051899	membrane depolarization	1.871501e-3
GO:0072404	signal transduction involved in G1/S transition checkpoint	1.885026e-3
GO:0006622	protein targeting to lysosome	1.891286e-3
GO:0007090	regulation of S phase of mitotic cell cycle	2.019357e-3
GO:0015718	monocarboxylic acid transport	2.031916e-3
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	2.041119e-3
GO:0021861	forebrain radial glial cell differentiation	2.041353e-3
GO:0021795	cerebral cortex cell migration	2.049500e-3
GO:0060041	retina development in camera-type eye	2.078200e-3
GO:0046427	positive regulation of JAK-STAT cascade	2.081977e-3
GO:0080134	regulation of response to stress	2.104092e-3
GO:0045740	positive regulation of DNA replication	2.122424e-3
GO:0042119	neutrophil activation	2.127339e-3
GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway	2.189071e-3
GO:0010746	regulation of plasma membrane long-chain fatty acid transport	2.217902e-3
GO:2000352	negative regulation of endothelial cell apoptosis	2.219543e-3
GO:0042769	DNA damage response, detection of DNA damage	2.219543e-3
GO:0035881	amacrine cell differentiation	2.227153e-3
GO:0031508	centromeric heterochromatin formation	2.227153e-3
GO:0043558	regulation of translational initiation in response to stress	2.297595e-3
GO:0072513	positive regulation of secondary heart field cardioblast proliferation	2.306122e-3
GO:0060011	Sertoli cell proliferation	2.306122e-3
GO:0006596	polyamine biosynthetic process	2.306122e-3
GO:0061308	cardiac neural crest cell development involved in heart development	2.352145e-3
GO:0060737	prostate gland morphogenetic growth	2.352145e-3
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	2.356660e-3
GO:0006004	fucose metabolic process	2.357862e-3
GO:0061029	eyelid development in camera-type eye	2.403732e-3
GO:0006090	pyruvate metabolic process	2.406927e-3
GO:0060536	cartilage morphogenesis	2.422893e-3
GO:0032094	response to food	2.508415e-3
GO:0032880	regulation of protein localization	2.537728e-3
GO:0031440	regulation of mRNA 3'-end processing	2.595937e-3
GO:0001915	negative regulation of T cell mediated cytotoxicity	2.609090e-3
GO:0045683	negative regulation of epidermis development	2.632216e-3
GO:0050880	regulation of blood vessel size	2.654291e-3
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	2.673019e-3
GO:0032200	telomere organization	2.695242e-3
GO:0008585	female gonad development	2.695459e-3
GO:0051346	negative regulation of hydrolase activity	2.733061e-3
GO:0035150	regulation of tube size	2.737857e-3
GO:0010766	negative regulation of sodium ion transport	2.742184e-3
GO:0009062	fatty acid catabolic process	2.757448e-3
GO:0060174	limb bud formation	2.804671e-3
GO:0051451	myoblast migration	2.819669e-3
GO:0031347	regulation of defense response	2.820562e-3
GO:0032147	activation of protein kinase activity	2.826615e-3
GO:0002053	positive regulation of mesenchymal cell proliferation	2.828649e-3
GO:0071403	cellular response to high density lipoprotein particle stimulus	2.828696e-3
GO:0071448	cellular response to alkyl hydroperoxide	2.828696e-3
GO:0071315	cellular response to morphine	2.828696e-3
GO:0031269	pseudopodium assembly	2.828696e-3
GO:0071307	cellular response to vitamin K	2.828696e-3
GO:0010430	fatty acid omega-oxidation	2.828696e-3
GO:0050904	diapedesis	2.828696e-3
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	2.871137e-3
GO:0060973	cell migration involved in heart development	2.913435e-3
GO:0060413	atrial septum morphogenesis	2.924880e-3
GO:0090187	positive regulation of pancreatic juice secretion	2.949662e-3
GO:0090340	positive regulation of secretion of lysosomal enzymes	2.949662e-3
GO:0090108	positive regulation of high-density lipoprotein particle assembly	2.949662e-3
GO:0070827	chromatin maintenance	2.949662e-3
GO:0035945	mitochondrial ncRNA surveillance	2.949662e-3
GO:0035946	mitochondrial mRNA surveillance	2.949662e-3
GO:0031118	rRNA pseudouridine synthesis	2.949662e-3
GO:0031623	receptor internalization	2.951414e-3
GO:0002009	morphogenesis of an epithelium	2.959163e-3
GO:0001766	membrane raft polarization	3.024812e-3
GO:0022602	ovulation cycle process	3.027453e-3
GO:0051893	regulation of focal adhesion assembly	3.057906e-3
GO:0048286	lung alveolus development	3.083891e-3
GO:0060279	positive regulation of ovulation	3.083924e-3
GO:0060414	aorta smooth muscle tissue morphogenesis	3.210993e-3
GO:0031340	positive regulation of vesicle fusion	3.210993e-3
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	3.228229e-3
GO:0001963	synaptic transmission, dopaminergic	3.273120e-3
GO:0003266	regulation of secondary heart field cardioblast proliferation	3.363477e-3
GO:0050866	negative regulation of cell activation	3.376823e-3
GO:0034720	histone H3-K4 demethylation	3.388394e-3
GO:0033261	regulation of S phase	3.430579e-3
GO:0045059	positive thymic T cell selection	3.465237e-3
GO:0048385	regulation of retinoic acid receptor signaling pathway	3.480294e-3
GO:0042760	very long-chain fatty acid catabolic process	3.542280e-3
GO:0003218	cardiac left ventricle formation	3.542280e-3
GO:0001547	antral ovarian follicle growth	3.584574e-3
GO:0060765	regulation of androgen receptor signaling pathway	3.602357e-3
GO:0003179	heart valve morphogenesis	3.659416e-3
GO:0033599	regulation of mammary gland epithelial cell proliferation	3.675591e-3
GO:0030330	DNA damage response, signal transduction by p53 class mediator	3.807249e-3
GO:0051239	regulation of multicellular organismal process	3.810494e-3
GO:0007283	spermatogenesis	3.813638e-3
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	3.932083e-3
GO:0021799	cerebral cortex radially oriented cell migration	3.932083e-3
GO:2000351	regulation of endothelial cell apoptosis	3.943886e-3
GO:0031394	positive regulation of prostaglandin biosynthetic process	3.961586e-3
GO:0006556	S-adenosylmethionine biosynthetic process	3.961586e-3
GO:0032943	mononuclear cell proliferation	4.004728e-3
GO:0046651	lymphocyte proliferation	4.066998e-3
GO:0060019	radial glial cell differentiation	4.122168e-3
GO:0060173	limb development	4.155996e-3
GO:0051665	membrane raft localization	4.182396e-3
GO:0034440	lipid oxidation	4.241487e-3
GO:0048483	autonomic nervous system development	4.268155e-3
GO:0034637	cellular carbohydrate biosynthetic process	4.279197e-3
GO:0051051	negative regulation of transport	4.357500e-3
GO:0008283	cell proliferation	4.399511e-3
GO:0006595	polyamine metabolic process	4.434654e-3
GO:0051930	regulation of sensory perception of pain	4.451365e-3
GO:0060751	branch elongation involved in mammary gland duct branching	4.524807e-3
GO:0003289	atrial septum primum morphogenesis	4.585455e-3
GO:0050727	regulation of inflammatory response	4.589363e-3
GO:0045830	positive regulation of isotype switching	4.606205e-3
GO:0051799	negative regulation of hair follicle development	4.615563e-3
GO:0009258	10-formyltetrahydrofolate catabolic process	4.616878e-3
GO:0003329	pancreatic PP cell fate commitment	4.616878e-3
GO:0003326	pancreatic A cell fate commitment	4.616878e-3
GO:0048745	smooth muscle tissue development	4.708262e-3
GO:0055107	Golgi to secretory granule transport	4.750378e-3
GO:0001811	negative regulation of type I hypersensitivity	4.750378e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	4.750378e-3
GO:0030328	prenylcysteine catabolic process	4.750378e-3
GO:0002638	negative regulation of immunoglobulin production	4.750378e-3
GO:0030324	lung development	4.752502e-3
GO:0060068	vagina development	4.785289e-3
GO:0006207	'de novo' pyrimidine base biosynthetic process	4.894215e-3
GO:0032494	response to peptidoglycan	4.956852e-3
GO:0060444	branching involved in mammary gland duct morphogenesis	4.974805e-3
GO:0033138	positive regulation of peptidyl-serine phosphorylation	4.991153e-3
GO:0021575	hindbrain morphogenesis	5.072790e-3
GO:0051100	negative regulation of binding	5.093516e-3
GO:0042701	progesterone secretion	5.237789e-3
GO:0035524	proline transmembrane transport	5.237789e-3
GO:0046324	regulation of glucose import	5.335774e-3
GO:0071391	cellular response to estrogen stimulus	5.347009e-3
GO:0043001	Golgi to plasma membrane protein transport	5.384416e-3
GO:0001707	mesoderm formation	5.398549e-3
GO:0006108	malate metabolic process	5.435840e-3
GO:0006275	regulation of DNA replication	5.462586e-3
GO:0060541	respiratory system development	5.480687e-3
GO:0048747	muscle fiber development	5.539435e-3
GO:0003170	heart valve development	5.586286e-3
GO:0090045	positive regulation of deacetylase activity	5.605561e-3
GO:0003151	outflow tract morphogenesis	5.610941e-3
GO:0070661	leukocyte proliferation	5.615409e-3
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	5.640997e-3
GO:0006820	anion transport	5.676639e-3
GO:0007346	regulation of mitotic cell cycle	5.696613e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	5.702219e-3
GO:0019751	polyol metabolic process	5.745922e-3
GO:0032512	regulation of protein phosphatase type 2B activity	5.825243e-3
GO:0021623	oculomotor nerve formation	5.825243e-3
GO:0003409	optic cup structural organization	5.825243e-3
GO:0005989	lactose biosynthetic process	5.825243e-3
GO:0003404	optic vesicle morphogenesis	5.825243e-3
GO:0008285	negative regulation of cell proliferation	5.836228e-3
GO:0003219	cardiac right ventricle formation	5.847278e-3
GO:0032870	cellular response to hormone stimulus	5.961612e-3
GO:0046633	alpha-beta T cell proliferation	5.998468e-3
GO:0060523	prostate epithelial cord elongation	6.096610e-3
GO:0021557	oculomotor nerve development	6.096610e-3
GO:0032025	response to cobalt ion	6.096610e-3
GO:0032328	alanine transport	6.125290e-3
GO:0060426	lung vasculature development	6.133379e-3
GO:0006893	Golgi to plasma membrane transport	6.133379e-3
GO:0090199	regulation of release of cytochrome c from mitochondria	6.192248e-3
GO:0030323	respiratory tube development	6.226896e-3
GO:0040018	positive regulation of multicellular organism growth	6.262182e-3
GO:0045445	myoblast differentiation	6.276071e-3
GO:0043923	positive regulation by host of viral transcription	6.350364e-3
GO:0035019	somatic stem cell maintenance	6.356676e-3
GO:0070372	regulation of ERK1 and ERK2 cascade	6.424815e-3
GO:0009220	pyrimidine ribonucleotide biosynthetic process	6.426257e-3
GO:0002707	negative regulation of lymphocyte mediated immunity	6.532489e-3
GO:0021563	glossopharyngeal nerve development	6.605392e-3
GO:0031952	regulation of protein autophosphorylation	6.732588e-3
GO:0045988	negative regulation of striated muscle contraction	6.769432e-3
GO:0071281	cellular response to iron ion	6.845432e-3
GO:0051057	positive regulation of small GTPase mediated signal transduction	6.877712e-3
GO:0006145	purine base catabolic process	7.012129e-3
GO:0055117	regulation of cardiac muscle contraction	7.013827e-3
GO:0010165	response to X-ray	7.104917e-3
GO:0001654	eye development	7.116469e-3
GO:0043010	camera-type eye development	7.122600e-3
GO:0043922	negative regulation by host of viral transcription	7.258858e-3
GO:0048333	mesodermal cell differentiation	7.275250e-3
GO:0010756	positive regulation of plasminogen activation	7.294669e-3
GO:0042921	glucocorticoid receptor signaling pathway	7.314795e-3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	7.314795e-3
GO:2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	7.318533e-3
GO:2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	7.318533e-3
GO:2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	7.318533e-3
GO:2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	7.318533e-3
GO:2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	7.318533e-3
GO:2000055	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification	7.318533e-3
GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	7.318533e-3
GO:2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	7.318533e-3
GO:0031914	negative regulation of synaptic plasticity	7.318533e-3
GO:0061310	canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	7.318533e-3
GO:0010543	regulation of platelet activation	7.585244e-3
GO:0060706	cell differentiation involved in embryonic placenta development	7.668706e-3
GO:0060463	lung lobe morphogenesis	7.727514e-3
GO:0050678	regulation of epithelial cell proliferation	7.743083e-3
GO:0008284	positive regulation of cell proliferation	7.787478e-3
GO:0045168	cell-cell signaling involved in cell fate commitment	7.836610e-3
GO:0034341	response to interferon-gamma	7.862112e-3
GO:0042698	ovulation cycle	7.874503e-3
GO:0032897	negative regulation of viral transcription	7.961138e-3
GO:0045916	negative regulation of complement activation	7.990620e-3
GO:0003018	vascular process in circulatory system	8.008372e-3