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UBERON:0000941

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Name:cranial nerve II
Namespace:FANTOM
Definition:"Cranial nerve which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]." [ISBN:0471209627, Wikipedia:Optic_nerve, ZFIN:curator]
Xrefs:
links:

AAO:0010345
EHDAA2:0001313
EHDAA:6788
EMAPA:17575
EMAPA:17846
FMA:50863
GAID:831
MA:0001097
MESH:A.08.800.800.120.680
ncithesaurus:Optic_Nerve
NIF_GrossAnatomy:birnlex_1640
OpenCyc:Mx4rvVjLm5wpEbGdrcN5Y29ycA
SCTID:180938001
TAO:0000435
VHOG:0000543
XAO:0000188

ZFA:0000435
Synonyms: "02 optic nerve" EXACT [AAO:0010345]
"CN-II" RELATED [ZFA:0000435]
"cranial II" EXACT []
"nervus opticus" EXACT []
"nervus opticus [II]" EXACT [FMA:50863, FMA:TA]
"optic II" EXACT [EHDAA2:0001313]
"optic II nerve" EXACT [EHDAA2:0001313]
"optic nerve" BROAD SENSU [FMA:50863, ZFA:0000435]
"optic nerve [II]" EXACT []
"second cranial nerve" EXACT []
Comments:AO notes: (relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class 'intra-ocular part of optic nerve' which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon. Structure notes: We are consistent here with the FMA in considering CN-II continuous with the retina. Editor notes: - determine the precise relationship between CN II and the CNS
Alt_id: UBERON:FBbt_00001956-FMA_50863-MA_0001097-XAO_0000188-ZFA_0000435
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0001785(cranial nerve),UBERON:0002464(nerve trunk),UBERON:0004121(ectoderm-derived structure),UBERON:0004904(nerve connecting eye with brain)
develops_from:UBERON:0003902(retinal neural layer)
part_of:UBERON:0002104(visual system)



Children

derives from:FF:0011166 (human optic nerve sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000941 (cranial nerve II), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr12:57628762..57628773,-#_b410062e5e3210cec6cadee190efeb01p@chr12:57628762..57628773, -
5.42e-195FFCP PHASE2:Hg19::chr12:57628762..57628773,-#_b410062e5e3210cec6cadee190efeb01p@chr12:57628762..57628773, -
9.37e-99FFCP PHASE1:Hg19::chr2:188432107..188432111,+#_fb3d956da5b1429f8324104720c91dc1p@chr2:188432107..188432111, +
9.37e-99FFCP PHASE1:Hg19::chr18:74702556..74702558,-#_fb3d956da5b1429f8324104720c91dc1p@chr18:74702556..74702558, -
9.37e-99FFCP PHASE2:Hg19::chr2:60133192..60133194,-#_fb3d956da5b1429f8324104720c91dc1p@chr2:60133192..60133194, -
9.37e-99FFCP PHASE1:Hg19::chr5:151258901..151258902,+#_fb3d956da5b1429f8324104720c91dc1p@chr5:151258901..151258902, +
9.37e-99FFCP PHASE2:Hg19::chr18:25161980..25161984,-#_fb3d956da5b1429f8324104720c91dc1p@chr18:25161980..25161984, -
9.37e-99FFCP PHASE1:Hg19::chr5:149250331..149250335,-#_fb3d956da5b1429f8324104720c91dc1p@chr5:149250331..149250335, -
9.37e-99FFCP PHASE1:Hg19::chr14:105807545..105807554,+#_fb3d956da5b1429f8324104720c91dc1p@chr14:105807545..105807554, +
9.37e-99FFCP PHASE1:Hg19::chr18:25161980..25161984,-#_fb3d956da5b1429f8324104720c91dc1p@chr18:25161980..25161984, -
9.37e-99FFCP PHASE1:Hg19::chr2:60133192..60133194,-#_fb3d956da5b1429f8324104720c91dc1p@chr2:60133192..60133194, -
9.37e-99FFCP PHASE2:Hg19::chr4:127394496..127394500,-#_fb3d956da5b1429f8324104720c91dc1p@chr4:127394496..127394500, -
9.37e-99FFCP PHASE1:Hg19::chr7:15056365..15056368,-#_fb3d956da5b1429f8324104720c91dc1p@chr7:15056365..15056368, -
9.37e-99FFCP PHASE2:Hg19::chr5:151258901..151258902,+#_fb3d956da5b1429f8324104720c91dc1p@chr5:151258901..151258902, +
9.37e-99FFCP PHASE2:Hg19::chr18:74702556..74702558,-#_fb3d956da5b1429f8324104720c91dc1p@chr18:74702556..74702558, -
9.37e-99FFCP PHASE2:Hg19::chr1:62928606..62928608,+#_fb3d956da5b1429f8324104720c91dc1p@chr1:62928606..62928608, +
9.37e-99FFCP PHASE1:Hg19::chr1:62928606..62928608,+#_fb3d956da5b1429f8324104720c91dc1p@chr1:62928606..62928608, +
9.37e-99FFCP PHASE2:Hg19::chr5:149250331..149250335,-#_fb3d956da5b1429f8324104720c91dc1p@chr5:149250331..149250335, -
9.37e-99FFCP PHASE2:Hg19::chr2:188432107..188432111,+#_fb3d956da5b1429f8324104720c91dc1p@chr2:188432107..188432111, +
9.37e-99FFCP PHASE2:Hg19::chr7:15056365..15056368,-#_fb3d956da5b1429f8324104720c91dc1p@chr7:15056365..15056368, -
9.37e-99FFCP PHASE1:Hg19::chr4:127394496..127394500,-#_fb3d956da5b1429f8324104720c91dc1p@chr4:127394496..127394500, -
9.37e-99FFCP PHASE2:Hg19::chr14:105807545..105807554,+#_fb3d956da5b1429f8324104720c91dc1p@chr14:105807545..105807554, +
2.55e-98FFCP PHASE1:Hg19::chrX:131884370..131884375,-#_6c40f5564be44919d423f220825d7960p@chrX:131884370..131884375, -
2.55e-98FFCP PHASE1:Hg19::chr9:74167667..74167687,-#_6c40f5564be44919d423f220825d7960p@chr9:74167667..74167687, -
2.55e-98FFCP PHASE2:Hg19::chr2:192696669..192696673,+#_6c40f5564be44919d423f220825d7960p@chr2:192696669..192696673, +
2.55e-98FFCP PHASE1:Hg19::chr8:133945378..133945386,+#_6c40f5564be44919d423f220825d7960p@chr8:133945378..133945386, +
2.55e-98FFCP PHASE1:Hg19::chr1:86911063..86911068,+#_6c40f5564be44919d423f220825d7960p@chr1:86911063..86911068, +
2.55e-98FFCP PHASE2:Hg19::chr1:203036812..203036840,+#_6c40f5564be44919d423f220825d7960p@chr1:203036812..203036840, +
2.55e-98FFCP PHASE2:Hg19::chr2:171939999..171940009,-#_6c40f5564be44919d423f220825d7960p@chr2:171939999..171940009, -
2.55e-98FFCP PHASE2:Hg19::chrX:131884370..131884375,-#_6c40f5564be44919d423f220825d7960p@chrX:131884370..131884375, -
2.55e-98FFCP PHASE1:Hg19::chr12:78359873..78359882,+#_6c40f5564be44919d423f220825d7960p41@NAV3
2.55e-98FFCP PHASE1:Hg19::chr6:121951983..121951986,+#_6c40f5564be44919d423f220825d7960p@chr6:121951983..121951986, +
2.55e-98FFCP PHASE2:Hg19::chr10:37679189..37679193,+#_6c40f5564be44919d423f220825d7960p@chr10:37679189..37679193, +
2.55e-98FFCP PHASE1:Hg19::chr8:90420477..90420478,-#_6c40f5564be44919d423f220825d7960p@chr8:90420477..90420478, -
2.55e-98FFCP PHASE1:Hg19::chr9:19514976..19514978,-#_6c40f5564be44919d423f220825d7960p@chr9:19514976..19514978, -
2.55e-98FFCP PHASE2:Hg19::chr1:169073323..169073334,+#_6c40f5564be44919d423f220825d7960p4@ENST00000415637
2.55e-98FFCP PHASE2:Hg19::chr13:64423563..64423566,+#_6c40f5564be44919d423f220825d7960p@chr13:64423563..64423566, +
2.55e-98FFCP PHASE1:Hg19::chr8:22000519..22000525,-#_6c40f5564be44919d423f220825d7960p@chr8:22000519..22000525, -
2.55e-98FFCP PHASE2:Hg19::chr17:47107522..47107524,+#_6c40f5564be44919d423f220825d7960p@chr17:47107522..47107524, +
2.55e-98FFCP PHASE1:Hg19::chr2:242808350..242808356,+#_6c40f5564be44919d423f220825d7960p2@LOC100131763
2.55e-98FFCP PHASE1:Hg19::chr11:79291300..79291301,+#_6c40f5564be44919d423f220825d7960p@chr11:79291300..79291301, +
2.55e-98FFCP PHASE1:Hg19::chr11:20791058..20791067,+#_6c40f5564be44919d423f220825d7960p10@NELL1
2.55e-98FFCP PHASE1:Hg19::chr2:192696669..192696673,+#_6c40f5564be44919d423f220825d7960p@chr2:192696669..192696673, +
2.55e-98FFCP PHASE2:Hg19::chr5:126962527..126962529,-#_6c40f5564be44919d423f220825d7960p@chr5:126962527..126962529, -
2.55e-98FFCP PHASE1:Hg19::chr2:240176859..240176904,-#_6c40f5564be44919d423f220825d7960p@chr2:240176859..240176904, -
2.55e-98FFCP PHASE2:Hg19::chr6:16317123..16317126,+#_6c40f5564be44919d423f220825d7960p@chr6:16317123..16317126, +
2.55e-98FFCP PHASE1:Hg19::chr5:111570472..111570478,-#_6c40f5564be44919d423f220825d7960p@chr5:111570472..111570478, -
2.55e-98FFCP PHASE2:Hg19::chr3:13992334..13992338,-#_6c40f5564be44919d423f220825d7960p@chr3:13992334..13992338, -
2.55e-98FFCP PHASE1:Hg19::chr7:95704857..95704906,+#_6c40f5564be44919d423f220825d7960p@chr7:95704857..95704906, +
2.55e-98FFCP PHASE1:Hg19::chr10:22768515..22768517,+#_6c40f5564be44919d423f220825d7960p@chr10:22768515..22768517, +
2.55e-98FFCP PHASE1:Hg19::chr6:168558338..168558388,-#_6c40f5564be44919d423f220825d7960p@chr6:168558338..168558388, -
2.55e-98FFCP PHASE2:Hg19::chr5:58471631..58471634,+#_6c40f5564be44919d423f220825d7960p@chr5:58471631..58471634, +
2.55e-98FFCP PHASE1:Hg19::chr5:1414652..1414695,+#_6c40f5564be44919d423f220825d7960p@chr5:1414652..1414695, +
2.55e-98FFCP PHASE2:Hg19::chr14:68527802..68527806,+#_6c40f5564be44919d423f220825d7960p@chr14:68527802..68527806, +
2.55e-98FFCP PHASE1:Hg19::chr3:163246025..163246029,+#_6c40f5564be44919d423f220825d7960p@chr3:163246025..163246029, +
2.55e-98FFCP PHASE1:Hg19::chr11:57030314..57030346,+#_6c40f5564be44919d423f220825d7960p@chr11:57030314..57030346, +
2.55e-98FFCP PHASE2:Hg19::chr1:1361494..1361497,+#_6c40f5564be44919d423f220825d7960p7@TMEM88B
2.55e-98FFCP PHASE2:Hg19::chr18:39859562..39859566,+#_6c40f5564be44919d423f220825d7960p@chr18:39859562..39859566, +
2.55e-98FFCP PHASE1:Hg19::chr2:97626726..97626741,+#_6c40f5564be44919d423f220825d7960p@chr2:97626726..97626741, +
2.55e-98FFCP PHASE1:Hg19::chr21:45724075..45724081,+#_6c40f5564be44919d423f220825d7960p@chr21:45724075..45724081, +
2.55e-98FFCP PHASE2:Hg19::chr1:66713214..66713221,+#_6c40f5564be44919d423f220825d7960p@chr1:66713214..66713221, +
2.55e-98FFCP PHASE2:Hg19::chr12:127992016..127992052,+#_6c40f5564be44919d423f220825d7960p@chr12:127992016..127992052, +
2.55e-98FFCP PHASE1:Hg19::chr8:126163123..126163134,+#_6c40f5564be44919d423f220825d7960p@chr8:126163123..126163134, +
2.55e-98FFCP PHASE1:Hg19::chr4:188536760..188536764,-#_6c40f5564be44919d423f220825d7960p@chr4:188536760..188536764, -
2.55e-98FFCP PHASE2:Hg19::chr4:139501766..139501798,-#_6c40f5564be44919d423f220825d7960p@chr4:139501766..139501798, -
2.55e-98FFCP PHASE2:Hg19::chr9:79519652..79519664,-#_6c40f5564be44919d423f220825d7960p@chr9:79519652..79519664, -
2.55e-98FFCP PHASE2:Hg19::chr5:24554148..24554153,+#_6c40f5564be44919d423f220825d7960p1@ENST00000510391
2.55e-98FFCP PHASE1:Hg19::chr3:181328472..181328478,+#_6c40f5564be44919d423f220825d7960p25@SOX2-OT
2.55e-98FFCP PHASE1:Hg19::chr7:152790347..152790351,+#_6c40f5564be44919d423f220825d7960p@chr7:152790347..152790351, +
2.55e-98FFCP PHASE1:Hg19::chr2:21277180..21277193,+#_6c40f5564be44919d423f220825d7960p@chr2:21277180..21277193, +
2.55e-98FFCP PHASE2:Hg19::chr10:118927879..118927891,+#_6c40f5564be44919d423f220825d7960p@chr10:118927879..118927891, +
2.55e-98FFCP PHASE2:Hg19::chr19:20382476..20382481,-#_6c40f5564be44919d423f220825d7960p@chr19:20382476..20382481, -
2.55e-98FFCP PHASE2:Hg19::chr3:39827273..39827281,+#_6c40f5564be44919d423f220825d7960p@chr3:39827273..39827281, +
2.55e-98FFCP PHASE1:Hg19::chr2:29645795..29645797,+#_6c40f5564be44919d423f220825d7960p@chr2:29645795..29645797, +
2.55e-98FFCP PHASE1:Hg19::chr7:103086717..103086724,+#_6c40f5564be44919d423f220825d7960p@chr7:103086717..103086724, +
2.55e-98FFCP PHASE1:Hg19::chr7:77789390..77789399,-#_6c40f5564be44919d423f220825d7960p@chr7:77789390..77789399, -
2.55e-98FFCP PHASE1:Hg19::chr1:203036812..203036840,+#_6c40f5564be44919d423f220825d7960p@chr1:203036812..203036840, +
2.55e-98FFCP PHASE2:Hg19::chr17:12935401..12935405,-#_6c40f5564be44919d423f220825d7960p@chr17:12935401..12935405, -
2.55e-98FFCP PHASE1:Hg19::chr5:109466651..109466653,+#_6c40f5564be44919d423f220825d7960p@chr5:109466651..109466653, +
2.55e-98FFCP PHASE1:Hg19::chr2:171939999..171940009,-#_6c40f5564be44919d423f220825d7960p@chr2:171939999..171940009, -
2.55e-98FFCP PHASE1:Hg19::chr14:37227792..37227796,-#_6c40f5564be44919d423f220825d7960p@chr14:37227792..37227796, -
2.55e-98FFCP PHASE2:Hg19::chr8:130597061..130597068,+#_6c40f5564be44919d423f220825d7960p@chr8:130597061..130597068, +
2.55e-98FFCP PHASE1:Hg19::chr5:103200303..103200307,+#_6c40f5564be44919d423f220825d7960p@chr5:103200303..103200307, +
2.55e-98FFCP PHASE1:Hg19::chr1:169073323..169073334,+#_6c40f5564be44919d423f220825d7960p4@ENST00000415637
2.55e-98FFCP PHASE1:Hg19::chr17:47107522..47107524,+#_6c40f5564be44919d423f220825d7960p@chr17:47107522..47107524, +
2.55e-98FFCP PHASE2:Hg19::chr7:88535666..88535671,+#_6c40f5564be44919d423f220825d7960p@chr7:88535666..88535671, +
2.55e-98FFCP PHASE2:Hg19::chr14:85119696..85119699,+#_6c40f5564be44919d423f220825d7960p@chr14:85119696..85119699, +
2.55e-98FFCP PHASE1:Hg19::chr18:61506836..61506840,+#_6c40f5564be44919d423f220825d7960p@chr18:61506836..61506840, +
2.55e-98FFCP PHASE2:Hg19::chr4:130221053..130221071,+#_6c40f5564be44919d423f220825d7960p@chr4:130221053..130221071, +
2.55e-98FFCP PHASE2:Hg19::chr21:22483836..22483880,+#_6c40f5564be44919d423f220825d7960p@chr21:22483836..22483880, +
2.55e-98FFCP PHASE2:Hg19::chr1:154942133..154942148,-#_6c40f5564be44919d423f220825d7960p@chr1:154942133..154942148, -
2.55e-98FFCP PHASE2:Hg19::chr14:88034381..88034386,-#_6c40f5564be44919d423f220825d7960p@chr14:88034381..88034386, -
2.55e-98FFCP PHASE1:Hg19::chr3:77060783..77060789,+#_6c40f5564be44919d423f220825d7960p@chr3:77060783..77060789, +
2.55e-98FFCP PHASE1:Hg19::chr18:39859562..39859566,+#_6c40f5564be44919d423f220825d7960p@chr18:39859562..39859566, +
2.55e-98FFCP PHASE1:Hg19::chr3:13992334..13992338,-#_6c40f5564be44919d423f220825d7960p@chr3:13992334..13992338, -
2.55e-98FFCP PHASE2:Hg19::chr16:51174920..51174928,-#_6c40f5564be44919d423f220825d7960p@chr16:51174920..51174928, -
2.55e-98FFCP PHASE2:Hg19::chr3:181328346..181328351,+#_6c40f5564be44919d423f220825d7960p22@SOX2-OT
2.55e-98FFCP PHASE1:Hg19::chr1:66713214..66713221,+#_6c40f5564be44919d423f220825d7960p@chr1:66713214..66713221, +
2.55e-98FFCP PHASE2:Hg19::chr14:68589926..68589929,+#_6c40f5564be44919d423f220825d7960p@chr14:68589926..68589929, +
2.55e-98FFCP PHASE1:Hg19::chr1:1361494..1361497,+#_6c40f5564be44919d423f220825d7960p7@TMEM88B










Property "Property value" (as page type) with input value "UBPROP:0000001 "A collection of nerve cells that project visual information from the eyes to the brain. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Fibrous, somatic sensory element covered by a fibrous connective-tissue sheath and is continuous with the layer of nerve cells on the inner surface of the eye.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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