UBERON:0002048
From FANTOM5_SSTAR
Name: | lung | ||
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Namespace: | FANTOM | ||
Definition: | "Respiration organ present in all air-breathing animals whose principal function is to transport oxygen from the atmosphere into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere[WP]. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax[GO]." [BTO:0000763, Wikipedia:Lung] | ||
Xrefs: |
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Synonyms: | "pulmo" EXACT LATIN [] | ||
Comments: | respiration organ in all air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart. Their principal function is to transport oxygen from the atmosphere into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere. This exchange of gases is accomplished in the mosaic of specialized cells that form millions of tiny, exceptionally thin-walled air sacs called alveoli. // Avian lungs do not have alveoli as mammalian lungs do, they have Faveolar lungs. They contain millions of tiny passages known as para-bronchi, connected at both ends by the dorsobronchi // Snakes and limbless lizards typically possess only the right lung as a major respiratory organ; the left lung is greatly reduced, or even absent. Amphisbaenians, however, have the opposite arrangement, with a major left lung, and a reduced or absent right lung [WP] | ||
Alt_id: | UBERON:FMA_68877-FMA_7195-MA_0000415-MIAA_0000135-XAO_0000119 | ||
Subset: |
major_organ organ_slim uberon_slim |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0000171(respiration organ),UBERON:0004119(endoderm-derived structure),UBERON:0005178(thoracic cavity element),UBERON:0015212(lateral structure) |
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develops_from: | UBERON:0000118(lung bud) |
part_of: | UBERON:0000170(pair of lungs) |
Children
is a: | UBERON:0002167 (right lung) |
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derives from: | FF:0010019 (human lung - adult sample),FF:0010068 (human lung - fetal sample),FF:0011307 (mouse lung- adult sample),FF:0011319 (mouse lung- embryo E12 sample),FF:0011338 (mouse lung- embryo E14 sample),FF:0011348 (mouse lung- embryo E15 sample),FF:0011357 (mouse lung- embryo E16 sample),FF:0011368 (mouse lung- embryo E17 sample),FF:0011394 (mouse lung- neonate N00 sample),FF:0011402 (mouse lung- neonate N06 sample),FF:0011408 (mouse lung- neonate N07 sample),FF:0011415 (mouse lung- neonate N10 sample),FF:0011428 (mouse lung- neonate N20 sample),FF:0011488 (mouse lung- neonate N25 sample),FF:0011489 (mouse lung- neonate N30 sample),FF:0011513 (mouse lung- embryo E18 sample),FF:0100353 (lung cell line sample) |
part of: | CL:0000082 (epithelial cell of lung),UBERON:0000101 (lobe of lung),UBERON:0000115 (lung epithelium),UBERON:0002173 (alveolar duct),UBERON:0002186 (bronchiole),UBERON:0002299 (alveolus of lung),CL:0002553 (lung fibroblast),UBERON:0006524 (alveolar system),UBERON:0008874 (pulmonary acinus),UBERON:0010368 (pulmonary lobule) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10019-101D1 (lung, adult, pool1)
- 10068-101I5 (lung, fetal, donor1)
- 10075-102A3 (lung, right lower lobe, adult, donor1)
- 10090-102B9
- 10408-106B3 (lung adenocarcinoma cell line:PC-14)
- 10446-106F5
- 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
- 10462-106H3
- 10468-106H9
- 10472-106I4
... further results Mouse (Mus musculus)
- 10019-101D1 (lung, adult, pool1)
- 10068-101I5 (lung, fetal, donor1)
- 10075-102A3 (lung, right lower lobe, adult, donor1)
- 10090-102B9
- 10408-106B3 (lung adenocarcinoma cell line:PC-14)
- 10446-106F5
- 10457-106G7 (squamous cell lung carcinoma cell line:LC-1F)
- 10462-106H3
- 10468-106H9
- 10472-106I4
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002048 (lung), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
P-value | FFCP | Short description |
---|---|---|
3.5e-81 | FFCP PHASE2:Mm9::chr11:85703335..85703350,+#_219ec111849cbff5792f352d28b3b951 | p4@Tbx4 |
3.5e-81 | FFCP PHASE1:Mm9::chr11:85703335..85703350,+#_219ec111849cbff5792f352d28b3b951 | p4@Tbx4 |
1.94e-76 | FFCP PHASE2:Mm9::chr11:85589157..85589190,-#_728abddb49b1e53cc00a266460b676ba | p1@ENSMUST00000134305 |
1.94e-76 | FFCP PHASE1:Mm9::chr11:85589157..85589190,-#_728abddb49b1e53cc00a266460b676ba | p1@ENSMUST00000134305 |
6.06e-75 | FFCP PHASE1:Mm9::chr11:85533239..85533252,-#_bdb69024b7792d06938403e5ab8c2e95 | p1@ENSMUST00000146806, p1@ENSMUST00000151652, p1@uc007krv.1, p1@uc007krw.1 |
6.06e-75 | FFCP PHASE2:Mm9::chr11:85533239..85533252,-#_bdb69024b7792d06938403e5ab8c2e95 | p1@ENSMUST00000146806, p1@ENSMUST00000151652, p1@uc007krv.1, p1@uc007krw.1 |
7.98e-75 | FFCP PHASE2:Mm9::chr11:85699562..85699575,+#_26099c5b79e5951186e3f10ac8607db3 | p6@Tbx4 |
7.98e-75 | FFCP PHASE1:Mm9::chr11:85699562..85699575,+#_26099c5b79e5951186e3f10ac8607db3 | p6@Tbx4 |
3.64e-74 | FFCP PHASE1:Mm9::chr4:138812977..138812992,+#_9564d34bec03a78a2521740dde0ec5f4 | p@chr4:138812977..138812992, + |
3.64e-74 | FFCP PHASE2:Mm9::chr4:138812977..138812992,+#_9564d34bec03a78a2521740dde0ec5f4 | p@chr4:138812977..138812992, + |
3.64e-74 | FFCP PHASE2:Mm9::chr8:94878479..94878503,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr8:94878479..94878503, - |
3.64e-74 | FFCP PHASE1:Mm9::chr12:57636003..57636017,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr12:57636003..57636017, - |
3.64e-74 | FFCP PHASE1:Mm9::chr11:59457994..59457997,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr11:59457994..59457997, - |
3.64e-74 | FFCP PHASE1:Mm9::chr12:57598716..57598720,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr12:57598716..57598720, - |
3.64e-74 | FFCP PHASE2:Mm9::chr12:57636003..57636017,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr12:57636003..57636017, - |
3.64e-74 | FFCP PHASE1:Mm9::chr8:94878479..94878503,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr8:94878479..94878503, - |
3.64e-74 | FFCP PHASE2:Mm9::chr11:59457994..59457997,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr11:59457994..59457997, - |
3.64e-74 | FFCP PHASE2:Mm9::chr12:57598716..57598720,-#_9564d34bec03a78a2521740dde0ec5f4 | p@chr12:57598716..57598720, - |
3.06e-70 | FFCP PHASE1:Mm9::chr12:57637649..57637665,-#_16157ceef2bf7b42c042c76b33042366 | p8@Nkx2-1 |
3.06e-70 | FFCP PHASE2:Mm9::chr12:57637649..57637665,-#_16157ceef2bf7b42c042c76b33042366 | p8@Nkx2-1 |
3.48e-70 | FFCP PHASE1:Mm9::chr12:57630487..57630498,-#_6dbeae56c1d4f8c119ef65927c6dc7aa | p2@E030019B13Rik |
3.48e-70 | FFCP PHASE2:Mm9::chr12:57630487..57630498,-#_6dbeae56c1d4f8c119ef65927c6dc7aa | p2@E030019B13Rik |
3.96e-70 | FFCP PHASE1:Mm9::chr2:17653019..17653038,-#_d90e8765ec106ab3d94f54f750ed7ccc | p10@Nebl |
3.96e-70 | FFCP PHASE2:Mm9::chr2:17653019..17653038,-#_d90e8765ec106ab3d94f54f750ed7ccc | p10@Nebl |
4.5e-70 | FFCP PHASE2:Mm9::chr12:57637700..57637717,-#_38b1fd967c6444dc97bd3a3c8b03cd3e | p9@Nkx2-1 |
4.5e-70 | FFCP PHASE1:Mm9::chr12:57637700..57637717,-#_38b1fd967c6444dc97bd3a3c8b03cd3e | p9@Nkx2-1 |
9.69e-69 | FFCP PHASE2:Mm9::chr19:18833097..18833135,+#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p3@Trpm6 |
9.69e-69 | FFCP PHASE2:Mm9::chr12:57630364..57630373,-#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p3@E030019B13Rik |
9.69e-69 | FFCP PHASE1:Mm9::chr12:57598537..57598547,-#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p@chr12:57598537..57598547, - |
9.69e-69 | FFCP PHASE1:Mm9::chr12:57630364..57630373,-#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p3@E030019B13Rik |
9.69e-69 | FFCP PHASE2:Mm9::chr12:57598537..57598547,-#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p@chr12:57598537..57598547, - |
9.69e-69 | FFCP PHASE1:Mm9::chr19:18833097..18833135,+#_30b80d1b1f5fd4bd0f5956d9e0b04fd0 | p3@Trpm6 |
1.11e-68 | FFCP PHASE2:Mm9::chr14:115241755..115241762,-#_789e7f56eae9c96f0b2d9a25f52fb734 | p@chr14:115241755..115241762, - |
1.11e-68 | FFCP PHASE1:Mm9::chr14:115241755..115241762,-#_789e7f56eae9c96f0b2d9a25f52fb734 | p@chr14:115241755..115241762, - |
1.27e-68 | FFCP PHASE1:Mm9::chr4:138812999..138813015,+#_d0f5fca9765aff09dc056f1e56acdf4b | p@chr4:138812999..138813015, + |
1.27e-68 | FFCP PHASE2:Mm9::chr4:138812999..138813015,+#_d0f5fca9765aff09dc056f1e56acdf4b | p@chr4:138812999..138813015, + |
4.47e-68 | FFCP PHASE1:Mm9::chr5:120282691..120282701,+#_0656af5a30499007d23183f04bea31cd | p@chr5:120282691..120282701, + |
4.47e-68 | FFCP PHASE2:Mm9::chr5:120282691..120282701,+#_0656af5a30499007d23183f04bea31cd | p@chr5:120282691..120282701, + |
5.44e-68 | FFCP PHASE2:Mm9::chr6:72255924..72255936,+#_78f8eb39883610a9976b03a984ecc6e9 | p4@Sftpb |
5.44e-68 | FFCP PHASE2:Mm9::chr6:72256828..72256859,+#_78f8eb39883610a9976b03a984ecc6e9 | p3@Sftpb |
5.44e-68 | FFCP PHASE1:Mm9::chr2:66524237..66524246,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr2:66524237..66524246, - |
5.44e-68 | FFCP PHASE2:Mm9::chr2:66524237..66524246,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr2:66524237..66524246, - |
5.44e-68 | FFCP PHASE2:Mm9::chr14:70922576..70922589,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr14:70922576..70922589, - |
5.44e-68 | FFCP PHASE1:Mm9::chr14:70922576..70922589,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr14:70922576..70922589, - |
5.44e-68 | FFCP PHASE1:Mm9::chr6:72256828..72256859,+#_78f8eb39883610a9976b03a984ecc6e9 | p3@Sftpb |
5.44e-68 | FFCP PHASE2:Mm9::chr14:70921265..70921285,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr14:70921265..70921285, - |
5.44e-68 | FFCP PHASE1:Mm9::chr1:184610062..184610074,+#_78f8eb39883610a9976b03a984ecc6e9 | p@chr1:184610062..184610074, + |
5.44e-68 | FFCP PHASE2:Mm9::chr1:184610062..184610074,+#_78f8eb39883610a9976b03a984ecc6e9 | p@chr1:184610062..184610074, + |
5.44e-68 | FFCP PHASE1:Mm9::chr6:72255924..72255936,+#_78f8eb39883610a9976b03a984ecc6e9 | p4@Sftpb |
5.44e-68 | FFCP PHASE1:Mm9::chr14:70921265..70921285,-#_78f8eb39883610a9976b03a984ecc6e9 | p@chr14:70921265..70921285, - |
5.08e-66 | FFCP PHASE1:Mm9::chr12:57630443..57630450,-#_67baccf18c7082ef5164dc24a9d7eafa | p4@E030019B13Rik |
5.08e-66 | FFCP PHASE2:Mm9::chr12:57630443..57630450,-#_67baccf18c7082ef5164dc24a9d7eafa | p4@E030019B13Rik |
4.92e-64 | FFCP PHASE1:Mm9::chr12:57623172..57623185,-#_7933a6201f3794ee85536fe649c0532a | p@chr12:57623172..57623185, - |
4.92e-64 | FFCP PHASE2:Mm9::chr14:70922007..70922052,+#_7933a6201f3794ee85536fe649c0532a | p@chr14:70922007..70922052, + |
4.92e-64 | FFCP PHASE2:Mm9::chr12:57623172..57623185,-#_7933a6201f3794ee85536fe649c0532a | p@chr12:57623172..57623185, - |
4.92e-64 | FFCP PHASE1:Mm9::chr14:70922007..70922052,+#_7933a6201f3794ee85536fe649c0532a | p@chr14:70922007..70922052, + |
5.59e-64 | FFCP PHASE1:Mm9::chr5:28785436..28785450,-#_345de06ed93652e7662302ba35fdb2ec | p@chr5:28785436..28785450, - |
5.59e-64 | FFCP PHASE2:Mm9::chr5:28785436..28785450,-#_345de06ed93652e7662302ba35fdb2ec | p@chr5:28785436..28785450, - |
6.35e-64 | FFCP PHASE1:Mm9::chr14:70922459..70922482,-#_c4555753bcb6cf24ffe0d903ba4ccb2e | p@chr14:70922459..70922482, - |
6.35e-64 | FFCP PHASE2:Mm9::chr14:70922459..70922482,-#_c4555753bcb6cf24ffe0d903ba4ccb2e | p@chr14:70922459..70922482, - |
2.55e-63 | FFCP PHASE1:Mm9::chr16:22439804..22439806,-#_b9e9cb28beb1e24c68a3f6ff3e34b735 | p4@Etv5 |
2.55e-63 | FFCP PHASE2:Mm9::chr16:22439804..22439806,-#_b9e9cb28beb1e24c68a3f6ff3e34b735 | p4@Etv5 |
1.43e-62 | FFCP PHASE2:Mm9::chr14:70923240..70923251,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr14:70923240..70923251, - |
1.43e-62 | FFCP PHASE2:Mm9::chr16:19706386..19706390,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p4@Lamp3 |
1.43e-62 | FFCP PHASE2:Mm9::chr6:72263977..72263993,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72263977..72263993, + |
1.43e-62 | FFCP PHASE1:Mm9::chr6:72263977..72263993,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72263977..72263993, + |
1.43e-62 | FFCP PHASE2:Mm9::chr14:70922486..70922510,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr14:70922486..70922510, - |
1.43e-62 | FFCP PHASE1:Mm9::chr14:70923240..70923251,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr14:70923240..70923251, - |
1.43e-62 | FFCP PHASE1:Mm9::chr16:19706386..19706390,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p4@Lamp3 |
1.43e-62 | FFCP PHASE1:Mm9::chr6:72264418..72264441,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72264418..72264441, + |
1.43e-62 | FFCP PHASE1:Mm9::chr14:70922486..70922510,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr14:70922486..70922510, - |
1.43e-62 | FFCP PHASE2:Mm9::chr6:72259797..72259814,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72259797..72259814, + |
1.43e-62 | FFCP PHASE1:Mm9::chr6:72259797..72259814,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72259797..72259814, + |
1.43e-62 | FFCP PHASE2:Mm9::chr6:72264890..72264911,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72264890..72264911, + |
1.43e-62 | FFCP PHASE1:Mm9::chr6:72264890..72264911,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72264890..72264911, + |
1.43e-62 | FFCP PHASE2:Mm9::chr6:72264418..72264441,+#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr6:72264418..72264441, + |
1.43e-62 | FFCP PHASE1:Mm9::chr12:57376690..57376716,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr12:57376690..57376716, - |
1.43e-62 | FFCP PHASE2:Mm9::chr12:57376690..57376716,-#_4743efbf66078b2a62e1e5ad24a3a4c0 | p@chr12:57376690..57376716, - |
1.63e-62 | FFCP PHASE2:Mm9::chr6:72264609..72264653,-#_af36b7cf71d497e01e8d9a4d381d5963 | p@chr6:72264609..72264653, - |
1.63e-62 | FFCP PHASE1:Mm9::chr6:72264609..72264653,-#_af36b7cf71d497e01e8d9a4d381d5963 | p@chr6:72264609..72264653, - |
1.87e-62 | FFCP PHASE1:Mm9::chr6:129378567..129378573,-#_f496c560db73a0374eccabe9a6f44525 | p@chr6:129378567..129378573, - |
1.87e-62 | FFCP PHASE2:Mm9::chr6:129378567..129378573,-#_f496c560db73a0374eccabe9a6f44525 | p@chr6:129378567..129378573, - |
1.91e-62 | FFCP PHASE1:Mm9::chr3:122432836..122432847,+#_3c249220c6d96947da7a80b212701bdc | p16@Pde5a |
1.91e-62 | FFCP PHASE2:Mm9::chr3:122432836..122432847,+#_3c249220c6d96947da7a80b212701bdc | p16@Pde5a |
3.02e-62 | FFCP PHASE2:Mm9::chr12:57637595..57637608,-#_bf0dd3b89dee6e7c35af37bb211e3688 | p7@Nkx2-1 |
3.02e-62 | FFCP PHASE1:Mm9::chr12:57637595..57637608,-#_bf0dd3b89dee6e7c35af37bb211e3688 | p7@Nkx2-1 |
5.06e-62 | FFCP PHASE2:Mm9::chr12:57636936..57636953,-#_f2282982ce082408699a2e7ffff3d411 | p@chr12:57636936..57636953, - |
5.06e-62 | FFCP PHASE1:Mm9::chr12:57636936..57636953,-#_f2282982ce082408699a2e7ffff3d411 | p@chr12:57636936..57636953, - |
7.58e-62 | FFCP PHASE2:Mm9::chr2:152591095..152591110,-#_d8b832e5201f56832e4fa4ec6435a795 | p@chr2:152591095..152591110, - |
7.58e-62 | FFCP PHASE1:Mm9::chr17:67043399..67043410,-#_d8b832e5201f56832e4fa4ec6435a795 | p9@Ptprm |
7.58e-62 | FFCP PHASE1:Mm9::chr2:126950686..126950702,-#_d8b832e5201f56832e4fa4ec6435a795 | p@chr2:126950686..126950702, - |
7.58e-62 | FFCP PHASE2:Mm9::chr6:72260761..72260774,-#_d8b832e5201f56832e4fa4ec6435a795 | p@chr6:72260761..72260774, - |
7.58e-62 | FFCP PHASE1:Mm9::chr6:72260761..72260774,-#_d8b832e5201f56832e4fa4ec6435a795 | p@chr6:72260761..72260774, - |
7.58e-62 | FFCP PHASE1:Mm9::chr14:41949922..41949935,+#_d8b832e5201f56832e4fa4ec6435a795 | p@chr14:41949922..41949935, + |
7.58e-62 | FFCP PHASE1:Mm9::chr12:57630433..57630438,-#_d8b832e5201f56832e4fa4ec6435a795 | p6@E030019B13Rik |
7.58e-62 | FFCP PHASE1:Mm9::chr14:70931508..70931519,+#_d8b832e5201f56832e4fa4ec6435a795 | p@chr14:70931508..70931519, + |
7.58e-62 | FFCP PHASE2:Mm9::chr6:72259749..72259765,+#_d8b832e5201f56832e4fa4ec6435a795 | p@chr6:72259749..72259765, + |
7.58e-62 | FFCP PHASE1:Mm9::chr14:41949964..41949979,+#_d8b832e5201f56832e4fa4ec6435a795 | p@chr14:41949964..41949979, + |
7.58e-62 | FFCP PHASE2:Mm9::chr12:57630433..57630438,-#_d8b832e5201f56832e4fa4ec6435a795 | p6@E030019B13Rik |
7.58e-62 | FFCP PHASE2:Mm9::chr2:126950686..126950702,-#_d8b832e5201f56832e4fa4ec6435a795 | p@chr2:126950686..126950702, - |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Either of two organs which allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.