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UBERON:0004237

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Name:blood vessel smooth muscle
Namespace:FANTOM
Definition:"smooth muscle found within, and composing the majority of the wall of blood vessels." [Wikipedia:Vascular_smooth_muscle]
Xrefs:
links:

BTO:0001431
MA:0000710
MESH:A.02.633.570.491
ncithesaurus:Vascular_Smooth_Muscle_Tissue
TAO:0005321

ZFA:0005321
Synonyms: "blood vessel involuntary muscle" EXACT [OBOL:automatic]
"blood vessel non-striated muscle" EXACT [OBOL:automatic]
"blood vessel smooth muscle tissue" EXACT [OBOL:automatic]
"involuntary muscle of blood vessel" EXACT [OBOL:automatic]
"non-striated muscle of blood vessel" EXACT [OBOL:automatic]
"smooth muscle of blood vessel" EXACT [OBOL:automatic]
"smooth muscle tissue of blood vessel" EXACT [OBOL:automatic]
"vascular smooth muscle" EXACT [ZFA:0005321]
"vascular smooth muscle tissue" EXACT []
Comments:Function notes: Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension.
Alt_id: UBERON:0010508

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0001135(smooth muscle tissue)
part_of:UBERON:0001981(blood vessel)



Children

is a:UBERON:0002111 (artery smooth muscle tissue),UBERON:0004178 (aorta smooth muscle tissue)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0004237 (blood vessel smooth muscle), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
1.58e-86FFCP PHASE2:Mm9::chrX:160839744..160839754,+#_ebbd76f3f8f080733acaf8f2585eeabap@chrX:160839744..160839754, +
1.58e-86FFCP PHASE1:Mm9::chr17:87574327..87574332,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:87574327..87574332, +
1.58e-86FFCP PHASE2:Mm9::chr17:87574327..87574332,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:87574327..87574332, +
1.58e-86FFCP PHASE1:Mm9::chr2:112043522..112043530,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr2:112043522..112043530, -
1.58e-86FFCP PHASE1:Mm9::chr2:178190171..178190178,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr2:178190171..178190178, +
1.58e-86FFCP PHASE1:Mm9::chrX:160839744..160839754,+#_ebbd76f3f8f080733acaf8f2585eeabap@chrX:160839744..160839754, +
1.58e-86FFCP PHASE1:Mm9::chr8:69228447..69228492,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr8:69228447..69228492, +
1.58e-86FFCP PHASE2:Mm9::chr11:50416871..50416882,+#_ebbd76f3f8f080733acaf8f2585eeabap5@Adamts2
1.58e-86FFCP PHASE1:Mm9::chr11:50416871..50416882,+#_ebbd76f3f8f080733acaf8f2585eeabap5@Adamts2
1.58e-86FFCP PHASE2:Mm9::chr8:69228447..69228492,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr8:69228447..69228492, +
1.58e-86FFCP PHASE2:Mm9::chr2:178190171..178190178,+#_ebbd76f3f8f080733acaf8f2585eeabap@chr2:178190171..178190178, +
1.58e-86FFCP PHASE1:Mm9::chr17:14827154..14827169,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:14827154..14827169, -
1.58e-86FFCP PHASE1:Mm9::chr17:14802633..14802637,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:14802633..14802637, -
1.58e-86FFCP PHASE2:Mm9::chr2:112043522..112043530,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr2:112043522..112043530, -
1.58e-86FFCP PHASE2:Mm9::chr17:14827154..14827169,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:14827154..14827169, -
1.58e-86FFCP PHASE2:Mm9::chr17:14802633..14802637,-#_ebbd76f3f8f080733acaf8f2585eeabap@chr17:14802633..14802637, -
5.79e-79FFCP PHASE1:Hg19::chr1:110429102..110429103,+#_6913bea811fdc29c6c6bf61c2e6bda3cp@chr1:110429102..110429103, +
5.79e-79FFCP PHASE2:Hg19::chr1:110429102..110429103,+#_6913bea811fdc29c6c6bf61c2e6bda3cp@chr1:110429102..110429103, +
1.33e-65FFCP PHASE2:Mm9::chr17:71340031..71340044,-#_f6663f11bcf7d9874050c2eeb34cba66p5@Myl12b
1.33e-65FFCP PHASE1:Mm9::chr11:118164535..118164544,-#_f6663f11bcf7d9874050c2eeb34cba66p@chr11:118164535..118164544, -
1.33e-65FFCP PHASE1:Mm9::chr8:69221163..69221172,+#_f6663f11bcf7d9874050c2eeb34cba66p6@Npy1r
1.33e-65FFCP PHASE2:Mm9::chr8:69221163..69221172,+#_f6663f11bcf7d9874050c2eeb34cba66p6@Npy1r
1.33e-65FFCP PHASE1:Mm9::chr17:71340031..71340044,-#_f6663f11bcf7d9874050c2eeb34cba66p5@Myl12b
1.33e-65FFCP PHASE2:Mm9::chr11:118164535..118164544,-#_f6663f11bcf7d9874050c2eeb34cba66p@chr11:118164535..118164544, -
1.33e-65FFCP PHASE2:Mm9::chrX:160840025..160840037,+#_f6663f11bcf7d9874050c2eeb34cba66p@chrX:160840025..160840037, +
1.33e-65FFCP PHASE1:Mm9::chrX:160840025..160840037,+#_f6663f11bcf7d9874050c2eeb34cba66p@chrX:160840025..160840037, +
1.33e-65FFCP PHASE2:Mm9::chr6:128920492..128920498,-#_f6663f11bcf7d9874050c2eeb34cba66p@chr6:128920492..128920498, -
1.33e-65FFCP PHASE2:Mm9::chrX:160840048..160840057,+#_f6663f11bcf7d9874050c2eeb34cba66p@chrX:160840048..160840057, +
1.33e-65FFCP PHASE1:Mm9::chr6:128920492..128920498,-#_f6663f11bcf7d9874050c2eeb34cba66p@chr6:128920492..128920498, -
1.33e-65FFCP PHASE1:Mm9::chrX:160840048..160840057,+#_f6663f11bcf7d9874050c2eeb34cba66p@chrX:160840048..160840057, +
2.21e-65FFCP PHASE1:Mm9::chr4:145000183..145000220,+#_a8891c3c0756558d1ef807620560067ap1@ENSMUST00000150529
2.21e-65FFCP PHASE2:Mm9::chr4:145000183..145000220,+#_a8891c3c0756558d1ef807620560067ap1@ENSMUST00000150529
3.28e-58FFCP PHASE1:Mm9::chr17:78907550..78907557,+#_61ae0279b955b5714773204e03839c78p8@Vit
3.28e-58FFCP PHASE2:Mm9::chrX:160811352..160811356,-#_61ae0279b955b5714773204e03839c78p@chrX:160811352..160811356, -
3.28e-58FFCP PHASE2:Mm9::chr10:33816181..33816195,-#_61ae0279b955b5714773204e03839c78p@chr10:33816181..33816195, -
3.28e-58FFCP PHASE1:Mm9::chrX:160811352..160811356,-#_61ae0279b955b5714773204e03839c78p@chrX:160811352..160811356, -
3.28e-58FFCP PHASE1:Mm9::chrX:160839012..160839023,+#_61ae0279b955b5714773204e03839c78p@chrX:160839012..160839023, +
3.28e-58FFCP PHASE1:Mm9::chr17:14817013..14817022,-#_61ae0279b955b5714773204e03839c78p@chr17:14817013..14817022, -
3.28e-58FFCP PHASE1:Mm9::chr10:33816181..33816195,-#_61ae0279b955b5714773204e03839c78p@chr10:33816181..33816195, -
3.28e-58FFCP PHASE1:Mm9::chr14:24251697..24251707,+#_61ae0279b955b5714773204e03839c78p@chr14:24251697..24251707, +
3.28e-58FFCP PHASE2:Mm9::chr17:14817013..14817022,-#_61ae0279b955b5714773204e03839c78p@chr17:14817013..14817022, -
3.28e-58FFCP PHASE1:Mm9::chr8:69857155..69857159,+#_61ae0279b955b5714773204e03839c78p@chr8:69857155..69857159, +
3.28e-58FFCP PHASE2:Mm9::chr8:69857155..69857159,+#_61ae0279b955b5714773204e03839c78p@chr8:69857155..69857159, +
3.28e-58FFCP PHASE2:Mm9::chr14:24251697..24251707,+#_61ae0279b955b5714773204e03839c78p@chr14:24251697..24251707, +
3.28e-58FFCP PHASE1:Mm9::chr10:96946110..96946113,+#_61ae0279b955b5714773204e03839c78p@chr10:96946110..96946113, +
3.28e-58FFCP PHASE2:Mm9::chr10:96946110..96946113,+#_61ae0279b955b5714773204e03839c78p@chr10:96946110..96946113, +
3.28e-58FFCP PHASE1:Mm9::chr17:87544959..87544962,+#_61ae0279b955b5714773204e03839c78p@chr17:87544959..87544962, +
3.28e-58FFCP PHASE2:Mm9::chr17:87544959..87544962,+#_61ae0279b955b5714773204e03839c78p@chr17:87544959..87544962, +
3.28e-58FFCP PHASE2:Mm9::chr17:78907550..78907557,+#_61ae0279b955b5714773204e03839c78p8@Vit
3.28e-58FFCP PHASE2:Mm9::chrX:160839012..160839023,+#_61ae0279b955b5714773204e03839c78p@chrX:160839012..160839023, +
3.28e-58FFCP PHASE2:Mm9::chr1:127573425..127573432,+#_61ae0279b955b5714773204e03839c78p12@Gpr39
3.28e-58FFCP PHASE1:Mm9::chr1:127573425..127573432,+#_61ae0279b955b5714773204e03839c78p12@Gpr39
1.26e-55FFCP PHASE2:Hg19::chr6:53359400..53359406,+#_0d192e03141d25bb1e5af60fbb7d2d8fp@chr6:53359400..53359406, +
1.26e-55FFCP PHASE1:Hg19::chr6:53359400..53359406,+#_0d192e03141d25bb1e5af60fbb7d2d8fp@chr6:53359400..53359406, +
4.9e-53FFCP PHASE2:Mm9::chr14:24251717..24251731,+#_f87af9963e5bcafb5affe925c78608eap@chr14:24251717..24251731, +
4.9e-53FFCP PHASE2:Mm9::chr8:69221150..69221161,+#_f87af9963e5bcafb5affe925c78608eap5@Npy1r
4.9e-53FFCP PHASE2:Mm9::chr7:91081998..91082010,-#_f87af9963e5bcafb5affe925c78608eap@chr7:91081998..91082010, -
4.9e-53FFCP PHASE2:Mm9::chr17:29227828..29227839,-#_f87af9963e5bcafb5affe925c78608eap@chr17:29227828..29227839, -
4.9e-53FFCP PHASE1:Mm9::chr13:113253807..113253846,+#_f87af9963e5bcafb5affe925c78608eap4@Il6st
4.9e-53FFCP PHASE2:Mm9::chr10:67598037..67598049,-#_f87af9963e5bcafb5affe925c78608eap@chr10:67598037..67598049, -
4.9e-53FFCP PHASE2:Mm9::chr13:113253807..113253846,+#_f87af9963e5bcafb5affe925c78608eap4@Il6st
4.9e-53FFCP PHASE1:Mm9::chr2:113589030..113589077,-#_f87af9963e5bcafb5affe925c78608eap@chr2:113589030..113589077, -
4.9e-53FFCP PHASE1:Mm9::chr7:91081998..91082010,-#_f87af9963e5bcafb5affe925c78608eap@chr7:91081998..91082010, -
4.9e-53FFCP PHASE1:Mm9::chr10:67821185..67821217,-#_f87af9963e5bcafb5affe925c78608eap@chr10:67821185..67821217, -
4.9e-53FFCP PHASE2:Mm9::chr10:67821185..67821217,-#_f87af9963e5bcafb5affe925c78608eap@chr10:67821185..67821217, -
4.9e-53FFCP PHASE1:Mm9::chr17:29227828..29227839,-#_f87af9963e5bcafb5affe925c78608eap@chr17:29227828..29227839, -
4.9e-53FFCP PHASE2:Mm9::chr2:113589030..113589077,-#_f87af9963e5bcafb5affe925c78608eap@chr2:113589030..113589077, -
4.9e-53FFCP PHASE1:Mm9::chr14:24251717..24251731,+#_f87af9963e5bcafb5affe925c78608eap@chr14:24251717..24251731, +
4.9e-53FFCP PHASE1:Mm9::chr8:69221150..69221161,+#_f87af9963e5bcafb5affe925c78608eap5@Npy1r
4.9e-53FFCP PHASE1:Mm9::chr10:67598037..67598049,-#_f87af9963e5bcafb5affe925c78608eap@chr10:67598037..67598049, -
7.35e-53FFCP PHASE1:Mm9::chr4:58219542..58219545,-#_12325f52df4c39873dbdaa5915c947b0p11@Svep1
7.35e-53FFCP PHASE2:Mm9::chr4:58219542..58219545,-#_12325f52df4c39873dbdaa5915c947b0p11@Svep1
1.1e-52FFCP PHASE2:Mm9::chrX:160838787..160838800,+#_c82b3bf0d06960d13a9ff51e88072891p@chrX:160838787..160838800, +
1.1e-52FFCP PHASE1:Mm9::chrX:160838787..160838800,+#_c82b3bf0d06960d13a9ff51e88072891p@chrX:160838787..160838800, +
1.65e-52FFCP PHASE2:Mm9::chr1:137662814..137662817,+#_f046a0ab772808dc451c58f3d9880583p5@Phlda3
1.65e-52FFCP PHASE1:Mm9::chr1:137662814..137662817,+#_f046a0ab772808dc451c58f3d9880583p5@Phlda3
5.51e-52FFCP PHASE2:Mm9::chr2:65009852..65009866,-#_db94146ac04e1edfdeb75772de1151a7p@chr2:65009852..65009866, -
5.51e-52FFCP PHASE1:Mm9::chr2:65009852..65009866,-#_db94146ac04e1edfdeb75772de1151a7p@chr2:65009852..65009866, -
1.18e-44FFCP PHASE1:Mm9::chr2:178190136..178190151,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr2:178190136..178190151, +
1.18e-44FFCP PHASE2:Mm9::chr17:14813242..14813246,-#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr17:14813242..14813246, -
1.18e-44FFCP PHASE2:Mm9::chr13:119579287..119579292,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr13:119579287..119579292, +
1.18e-44FFCP PHASE2:Mm9::chrX:160838683..160838694,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chrX:160838683..160838694, +
1.18e-44FFCP PHASE2:Mm9::chr2:178190136..178190151,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr2:178190136..178190151, +
1.18e-44FFCP PHASE1:Mm9::chrX:160838683..160838694,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chrX:160838683..160838694, +
1.18e-44FFCP PHASE1:Mm9::chr13:119579287..119579292,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr13:119579287..119579292, +
1.18e-44FFCP PHASE2:Mm9::chr11:86417559..86417568,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr11:86417559..86417568, +
1.18e-44FFCP PHASE2:Mm9::chr1:127573864..127573879,+#_6a7cd2d917d7300a9a4ab9b995c15acdp10@Gpr39
1.18e-44FFCP PHASE1:Mm9::chr1:127573864..127573879,+#_6a7cd2d917d7300a9a4ab9b995c15acdp10@Gpr39
1.18e-44FFCP PHASE1:Mm9::chr17:14813242..14813246,-#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr17:14813242..14813246, -
1.18e-44FFCP PHASE1:Mm9::chr11:86417559..86417568,+#_6a7cd2d917d7300a9a4ab9b995c15acdp@chr11:86417559..86417568, +
1.66e-44FFCP PHASE1:Mm9::chrX:160839663..160839673,+#_5ade0400a51e95ec22e8d534ef485173p@chrX:160839663..160839673, +
1.66e-44FFCP PHASE2:Mm9::chr13:119503185..119503195,+#_5ade0400a51e95ec22e8d534ef485173p9@Fgf10
1.66e-44FFCP PHASE1:Mm9::chr13:119503185..119503195,+#_5ade0400a51e95ec22e8d534ef485173p9@Fgf10
1.66e-44FFCP PHASE2:Mm9::chrX:160839663..160839673,+#_5ade0400a51e95ec22e8d534ef485173p@chrX:160839663..160839673, +
2.33e-44FFCP PHASE2:Mm9::chr17:75790300..75790304,+#_708dac618a6f0dfaf92c850686aacd4dp@chr17:75790300..75790304, +
2.33e-44FFCP PHASE1:Mm9::chr17:75790300..75790304,+#_708dac618a6f0dfaf92c850686aacd4dp@chr17:75790300..75790304, +
3.27e-44FFCP PHASE2:Mm9::chr1:127573708..127573719,+#_6da712fbf74624270a9f49037c04ec8cp9@Gpr39
3.27e-44FFCP PHASE1:Mm9::chr1:127573708..127573719,+#_6da712fbf74624270a9f49037c04ec8cp9@Gpr39
4.58e-44FFCP PHASE1:Mm9::chr17:14813991..14813999,+#_c3e07cf24b4518ad4e9f6c20a9041852p@chr17:14813991..14813999, +
4.58e-44FFCP PHASE2:Mm9::chr17:14813991..14813999,+#_c3e07cf24b4518ad4e9f6c20a9041852p@chr17:14813991..14813999, +