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Coexpression cluster:C2829: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0007023!1.27e-28!115;UBERON:0000073!5.30e-28!94;UBERON:0001016!5.30e-28!94;UBERON:0001017!1.87e-27!82;UBERON:0005743!6.13e-27!86;UBERON:0001049!2.96e-26!57;UBERON:0005068!2.96e-26!57;UBERON:0006241!2.96e-26!57;UBERON:0007135!2.96e-26!57;UBERON:0000955!3.63e-24!69;UBERON:0006238!3.63e-24!69;UBERON:0003080!5.35e-23!42;UBERON:0002780!2.19e-22!41;UBERON:0001890!2.19e-22!41;UBERON:0006240!2.19e-22!41;UBERON:0002616!3.84e-21!59;UBERON:0000033!1.49e-18!123;UBERON:0002020!3.05e-18!34;UBERON:0003528!3.05e-18!34;UBERON:0001893!5.43e-18!34;UBERON:0000153!5.91e-18!129;UBERON:0007811!5.91e-18!129;UBERON:0003075!2.07e-17!86;UBERON:0007284!2.07e-17!86;UBERON:0002791!2.15e-17!33;UBERON:0001869!3.27e-17!32;UBERON:0002346!2.13e-16!90;UBERON:0004121!5.88e-16!169;UBERON:0003056!1.79e-15!61;UBERON:0000924!2.04e-15!173;UBERON:0006601!2.04e-15!173;UBERON:0002619!1.43e-14!22;UBERON:0000956!1.39e-13!25;UBERON:0000203!1.39e-13!25;UBERON:0001950!1.75e-13!20;UBERON:0000062!1.14e-11!511;UBERON:0000922!4.41e-09!612;UBERON:0000468!3.30e-08!659;UBERON:0002050!9.32e-08!605;UBERON:0005423!9.32e-08!605;UBERON:0000923!1.72e-07!604;UBERON:0005291!1.72e-07!604;UBERON:0006598!1.72e-07!604;UBERON:0002532!1.72e-07!604;UBERON:0000480!3.02e-07!626;UBERON:0000467!3.38e-07!625
|ontology_enrichment_uberon=UBERON:0007023!1.27e-28!115;UBERON:0000073!5.30e-28!94;UBERON:0001016!5.30e-28!94;UBERON:0001017!1.87e-27!82;UBERON:0005743!6.13e-27!86;UBERON:0001049!2.96e-26!57;UBERON:0005068!2.96e-26!57;UBERON:0006241!2.96e-26!57;UBERON:0007135!2.96e-26!57;UBERON:0000955!3.63e-24!69;UBERON:0006238!3.63e-24!69;UBERON:0003080!5.35e-23!42;UBERON:0002780!2.19e-22!41;UBERON:0001890!2.19e-22!41;UBERON:0006240!2.19e-22!41;UBERON:0002616!3.84e-21!59;UBERON:0000033!1.49e-18!123;UBERON:0002020!3.05e-18!34;UBERON:0003528!3.05e-18!34;UBERON:0001893!5.43e-18!34;UBERON:0000153!5.91e-18!129;UBERON:0007811!5.91e-18!129;UBERON:0003075!2.07e-17!86;UBERON:0007284!2.07e-17!86;UBERON:0002791!2.15e-17!33;UBERON:0001869!3.27e-17!32;UBERON:0002346!2.13e-16!90;UBERON:0004121!5.88e-16!169;UBERON:0003056!1.79e-15!61;UBERON:0000924!2.04e-15!173;UBERON:0006601!2.04e-15!173;UBERON:0002619!1.43e-14!22;UBERON:0000956!1.39e-13!25;UBERON:0000203!1.39e-13!25;UBERON:0001950!1.75e-13!20;UBERON:0000062!1.14e-11!511;UBERON:0000922!4.41e-09!612;UBERON:0000468!3.30e-08!659;UBERON:0002050!9.32e-08!605;UBERON:0005423!9.32e-08!605;UBERON:0000923!1.72e-07!604;UBERON:0005291!1.72e-07!604;UBERON:0006598!1.72e-07!604;UBERON:0002532!1.72e-07!604;UBERON:0000480!3.02e-07!626;UBERON:0000467!3.38e-07!625
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3,0.178782,0.019419,0.0866228,0.271849,0.282657,0.105411,0.0997542,0.209692,0.248936,0.0725263,0.102587,0.0742013,0.0552936,0.0457886,0.0514927,0.0593965,0.220368,0.258624,0.064656,0.226143,3.01367e-07,0.0438521,0.435508,0.281453,0.0522771,0.0787278,0.164404,0.159873,0.142462,0.143935,0.332403,0.0379537,0.0922008,0.187953,0.051459,0.114868,0.0726892,0.18732,0.32305,0.278397,0.245002,0.170848,0.487259,0.302909,0.363016,0.100188,0.223102,0.107653,0.235857,0.419621,0.191914,0.184022,0.216557,0.182956,0.116818,0.000162768,0.0757944,0.0625685,0.124464,0.544477,0.173134,0.101893,0.142875,0.167635,0.171311,0.0210393,0.0465855,0.0685131,0.130287,0.0661526,0.0815772,0.0993937,0.122878,0.187329,0.0451012,0.0976639,0.351199,0.267945,0.758305,0.278645,0.365775,0.155708,0.248017,0.22995,1.77795e-08,0.0760151,0.0629459,0.143933,0.0803251,0.226641,0.0832234,0.0939463,0.286748,0.0779623,0.0471607,0.163865,0.226359,0.404165,0.0339072,0.265324,0.279778,0.141699,0.0887743,0.142302,0.0653269,0.125712,0.264432,0.0994829,0.0604041,0.144185,0.0925862,0.289561,0.199201,0.049937,0.172796,3.68389e-05,0.071232,0.149346,0.121978,0.22302,0.137423,0.284016,0.0754883,0.299492,0.100006,0.0756617,0.197817,0.251078,0.000372899,0.133127,0.016612,0.223717,0.426452,0.196838,0.0826805,0.246601,0.00140087,0.608002,0.202165,0.0946865,0.120618,0.079499,0.18762,0.195618,0.127688,0.201169,0.220353,0.24948,0.178639,0.291976,0.320355,0.364334,0.0127656,7.06917e-06,0.415419,0.14794,0.147307,0.240761,0.0277041,0.124417,0.335582,0.317428,0.182843,0.130771,0.06079,0.135777,0.147842,0.0339286,0.217363,0.119015,0.690952,0.21618,0.243266,0.107021,0.238657,0.20272,0.392453,0.0164195,0.0780061,0.315336,0.230477,0.279823,0.0487563,0.00567943,0.0420826,0.0478217,0.158752,0.170854,0.0575231,0.174063,0.0368787,0.459091,0.54832,0.0338476,0.296013,0.649813,0.537932,0.459994,0.523209,0.548059,0.25423,0.490559,0.45013,0.153911,0.135135,0.685908,0.747471,0.529642,0.818701,0.483077,0.590496,0.0147688,0.541914,0.627201,0.938109,0.00013331,0.290703,0.622694,0.722684,0.139104,0.360199,0.608176,0.657141,0.519564,0.365494,0.212703,0.0515679,0.364079,0.680099,0.579886,0.421038,0.569409,0.328518,0.545608,0.310552,0.594773,0.483764,0.261345,0.784052,0.209437,0.843495,0.0134757,0.598945,0.882403,0.464001,0.871271,0.579004,0.605327,0.113944,0.586133,0.261575,0.257956,0.264245,0.379063,0.326516,0.522925,0.436016,0.475063,0.202522,0.183837,0.507324,0.126097,0.3955,2.77082e-06,0.212239,0.294954,0.156999,0.35974,0.667777,0.39549,0.234254,0.357409,0.328421,0.00995016,0.50338,0.620526,0.404625,0.416164,0.424691,0.132999,0.479581,0.62689,0.884725,0.642173,0.284496,0.16228,0.512178,0.563206,0.260945,0.684899,0.263302,0.552023,0.180735,0.0182207,0.216102,0.254659,0.109605,0.397869,0.582542,0.226491,0.417131,0.463987,0.627953,0.503881,0.454761,0.0840572,0.142363,0.000399596,0.301581,0.261657,0.00938391,0.131322,0.545655,0.438176,0.349112,0.741477,0.385425,0.307816,0.461541,0.386339,0.382854,0.598787,0.478745,0.611661,0.00716065,0.475047,0.557967,0.608127,0.282281,0.612712,0.2536,0.246827,0.564333,0.70712,0.387134,0.559969,0.358813,0.303004,0.574252,0.493455,0.346636,0.457747,0.348802,0.476541,0.579645,0.447581,0.42505,0.254628,0.713293,0.00057542,0.416962,0.264955,0.378333,0.738545,0.264038,0.22798,0.102495,0.350933,0.263896,0.0446972,0.24452,0.329284,0.242783,0.0947248,0.336551,0.210656,0.246234,0.211271,0.281295,0.267248,0.118257,0.125087,0.215123,0.321224,0.469461,0.325254,0.266651,0.546295,0.231754,0.249415,0.0445044,0.285648,0.427316,0.0140903,0.279553,0.25563,0.00284468,0.160955,0.256687,0.0432189,0.00782177,0.16188,0.23235,0.00521493,0.353147,0.112422,0.170886,0.267687,0.0560879,0.284866,0.0887542,0.267811,0.338547,0.147872,0.189388,0.293546,0.210125,0.000456832,0.218414,0.0509944,0.0871471,0.0689852,0.0602698,0.00888732,0.259328,0.437467,0.0217216,0.15696,0.129351,0.141936,0.0786166,0.276997,0.205513,0.282389,0.251421,0.162089,0.00796989,0.387837,0.233244,0.0231432,0.327401,0.195748,0.27845,0.000801851,0.0308468,0.239139,0.095257,0.328852,0.332769,0.00372893,0.274403,0.266687,0.184534,0.248707,0.31749,0.15156,0.287598,0.313858,0.223773,0.25788,0.181895,0.253768,0.00626086,0.202977,0.170837,0.327002,0.28543,0.222656,0.00239762,0.127111,0.259989,0.390754,0.0102294,0.279739,0.108118,0.000269064,0.139723,0.0708274,0.0710478,0.196248,0.102645,0.0539258,0.0709978,0.0944985,0.332746,0.271338,0.242121,0.0498554,0.244395,0.106889,0.128632,0.0845989,0.159153,0.0842401,0.13698,0.0874421,0.100355,0.167854,0.142846,0.0583767,0.088258,0.117657,0.0486914,0.175784,0.262778,0.373453,0.362662,0.433518,0.184359,0.334474,0.325785,0.257476,0.291176,0.081972,0.322827,0.229571,0.359036,0.335984,0.171704,0.208256,0.003871,0.256405,0.362898,0.302133,0.40806,0.151361,0.279606,0.0457079,0.150674,0.251128,0.246177,0.0729297,0.35852,0.318525,0.213257,0.287217,0.122782,0.410951,0.289049,0.266974,0.125746,0.112897,0.398354,0.222091,0.205977,0.34423,0.0936726,0.343425,0.132374,0.285122,0.22741,0.203996,0.276721,0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}}
}}

Revision as of 13:20, 5 September 2012


Full id: C2829_pineal_cerebellum_occipital_thalamus_medial_globus_parietal



Phase1 CAGE Peaks

Hg19::chr5:77656342..77656362,+p2@SCAMP1
Hg19::chr5:77656368..77656380,+p5@SCAMP1
Hg19::chr5:77656382..77656393,+p6@SCAMP1
Hg19::chr5:77656394..77656413,+p3@SCAMP1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism1.27e-28115
regional part of nervous system5.30e-2894
nervous system5.30e-2894
central nervous system1.87e-2782
neural tube2.96e-2657
neural rod2.96e-2657
future spinal cord2.96e-2657
neural keel2.96e-2657
brain3.63e-2469
future brain3.63e-2469
anterior neural tube5.35e-2342
regional part of forebrain2.19e-2241
forebrain2.19e-2241
future forebrain2.19e-2241
regional part of brain3.84e-2159
head1.49e-18123
gray matter3.05e-1834
brain grey matter3.05e-1834
telencephalon5.43e-1834
anterior region of body5.91e-18129
craniocervical region5.91e-18129
neural plate2.07e-1786
presumptive neural plate2.07e-1786
regional part of telencephalon2.15e-1733
cerebral hemisphere3.27e-1732
neurectoderm2.13e-1690
ectoderm-derived structure5.88e-16169
pre-chordal neural plate1.79e-1561
ectoderm2.04e-15173
presumptive ectoderm2.04e-15173
regional part of cerebral cortex1.43e-1422
cerebral cortex1.39e-1325
pallium1.39e-1325
neocortex1.75e-1320
organ1.14e-11511
embryo4.41e-09612
multi-cellular organism3.30e-08659
embryonic structure9.32e-08605
developing anatomical structure9.32e-08605
germ layer1.72e-07604
embryonic tissue1.72e-07604
presumptive structure1.72e-07604
epiblast (generic)1.72e-07604
anatomical group3.02e-07626
anatomical system3.38e-07625


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
BCL11A#53335428.36945510360711.542446414682e-065.90295203748529e-05
BCL3#602434.54710280373837.01262157705428e-073.15278168267745e-05
BCLAF1#9774421.65264761012184.54636978835329e-060.000141779132375584
CCNT2#90546.336201576962630.0006203100587215640.00513348353588126
CHD2#1106410.34402283411698.73193255208051e-050.001293185342891
CTCF#1066445.360256373075030.001211145381643620.00819400223576332
E2F1#186944.907389214879320.001724022357361790.0106762627323159
E2F6#187645.017155731697390.00157802193473060.0099883050206866
EBF1#187948.9064668465690.00015887907472010.00199965915698874
EGR1#195844.988179094810140.001615011500076050.0101620789285723
ELF1#199744.258097958807540.003041525565781240.016122107727992
ETS1#211349.728760922202340.0001115955317418140.00154759337930996
FOSL1#8061439.7135797163734.01511434669553e-071.93956765612643e-05
GABPB1#255347.067683836182170.0004006876864423170.00390805204373824
HDAC2#3066413.41562023662633.0859005065161e-050.000627997589633739
HEY1#2346244.040111043105710.00375304636917980.0186516492862607
HMGN3#932448.178547723350590.0002234570284440470.00248537045725962
IRF4#3662421.91451268674414.33289161192893e-060.000136631300440292
JUND#372746.994663941871030.000417684217818580.00392359435372861
MAX#414946.452555509007120.0005767613195645490.00486208535426604
MEF2A#4205418.74323090964418.0978922767748e-060.000224631015005068
MEF2C#4208441.31135449262413.42889182145094e-071.69962046958004e-05
MXI1#460149.96157162875930.0001015224754950450.00142703981402786
MYC#460945.22228187160940.001344309395272740.00889497775803911
NFKB1#479045.488063424193840.001102199566301980.00769109510957522
NR3C1#2908414.9730233311731.98868032687801e-050.000444174047602251
NRF1#4899412.21027944771094.49717228915276e-050.000795394033373116
PAX5#507946.669565531177830.0005052774169483260.00444796595993478
POU2F2#545249.106124057742520.000145395665174930.00188703589849689
RAD21#5885410.35503389545638.6948481184721e-050.00129818619391724
REST#597849.650028716128020.0001152825614219170.00157426718519137
RXRA#6256420.07461713913336.1537798808435e-060.000182531842367343
SIN3A#2594245.408884726815140.001168172384885160.00797820793258049
SMC3#9126415.04493284493281.95092670935632e-050.000439311846913464
SP1#666745.69838137814090.0009482606065333980.00685555790431549
SPI1#668848.204323508522730.000220661881527680.00249817953873923
SRF#6722413.79717826216782.75840773062708e-050.000585420331190736
STAT1#6772420.70658749719925.43610708103893e-060.000165570600010681
STAT2#6773465.26377118644075.50053512607993e-083.46693052524237e-06
TAF1#687243.343046285745290.008005664898701650.0323156818442199
TAF7#6879411.43306940492395.85061525419808e-050.000971743649066783
TBP#690843.706770687096390.005296377814784350.0244918486871048
TCF12#6938410.63446490218647.8163066689251e-050.00120242635468533
TCF7L2#6934410.77017656313737.42969445082454e-050.00115709791045282
TFAP2A#7020416.5186343730451.34240829060362e-050.00032711101134473
TFAP2C#7022410.80922860986027.32289634782688e-050.00114782526139981
USF1#739146.361499277207960.0006105011399140830.00508859764975953
YY1#752844.911170749853860.00171871838055440.0107024343517005
ZBTB33#10009431.66472502998129.93721537730495e-074.20515736138716e-05
ZBTB7A#5134147.35190930787590.000342223540015990.00347206958380901
ZNF263#1012748.221841637010680.0002187871180958320.00249807672754024



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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