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MCL coexpression mm9:918: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0005522;profilin binding;0.0414121760644356;215280!
|ontology_enrichment_celltype=CL:0000988!1.45e-08!32;CL:0002032!1.45e-08!32;CL:0000037!1.45e-08!32;CL:0000566!1.45e-08!32;CL:0000837!1.45e-08!32;CL:0002031!1.25e-07!25;CL:0002320!5.68e-07!46;CL:0000134!5.68e-07!46;CL:0000838!7.49e-07!12
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002193!2.18e-15!48;UBERON:0002405!2.18e-15!48;UBERON:0002390!1.56e-14!45;UBERON:0003061!1.56e-14!45;UBERON:0003081!1.71e-11!87;UBERON:0000077!5.17e-10!35;UBERON:0000926!1.37e-09!120;UBERON:0004120!1.37e-09!120;UBERON:0006603!1.37e-09!120;UBERON:0004177!5.41e-09!29;UBERON:0005057!5.41e-09!29;UBERON:0001041!1.10e-07!80;UBERON:0002384!5.68e-07!46;UBERON:0002204!6.38e-07!32;UBERON:0003408!9.04e-07!24
}}

Latest revision as of 16:06, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:82834272..82834285,-p2@LOC100505399
p2@Slfn8
Mm9::chr11:82834290..82834345,-p1@LOC100505399
p1@Slfn8
Mm9::chr1:175872576..175872603,-p1@Gm16340
p1@Ifi203
p1@LOC100044071
p1@LOC100048583
Mm9::chr2:73324462..73324475,-p2@Wipf1
Mm9::chr4:149944223..149944234,-p@chr4:149944223..149944234
-
Mm9::chr5:121262634..121262677,+p1@Oas1b
Mm9::chr7:111594584..111594617,-p@chr7:111594584..111594617
-
Mm9::chr7:111613655..111613689,-p1@Trim30a


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005522profilin binding0.0414121760644356



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
hemolymphoid system2.18e-1548
immune system2.18e-1548
hematopoietic system1.56e-1445
blood island1.56e-1445
lateral plate mesoderm1.71e-1187
mixed endoderm/mesoderm-derived structure5.17e-1035
mesoderm1.37e-09120
mesoderm-derived structure1.37e-09120
presumptive mesoderm1.37e-09120
hemopoietic organ5.41e-0929
immune organ5.41e-0929
foregut1.10e-0780
connective tissue5.68e-0746
musculoskeletal system6.38e-0732
gland of gut9.04e-0724


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0545917
MA0004.10.434673
MA0006.10.271714
MA0007.10.419994
MA0009.10.870101
MA0014.10.0611475
MA0017.10.296816
MA0019.10.688051
MA0024.10.826339
MA0025.11.10341
MA0027.12.51754
MA0028.10.281528
MA0029.10.804619
MA0030.10.811181
MA0031.10.775627
MA0038.10.577528
MA0040.10.882616
MA0041.10.360875
MA0042.10.348174
MA0043.10.966833
MA0046.10.906029
MA0048.10.335404
MA0050.14.16051
MA0051.12.44382
MA0052.10.890676
MA0055.10.523649
MA0056.10
MA0057.10.31126
MA0058.10.341628
MA0059.10.353484
MA0060.10.574356
MA0061.10.638933
MA0063.10
MA0066.11.39085
MA0067.11.21448
MA0068.10.0965831
MA0069.10.891016
MA0070.10.881319
MA0071.10.471969
MA0072.10.872842
MA0073.11.1212e-05
MA0074.10.531046
MA0076.10.315013
MA0077.10.851175
MA0078.10.61926
MA0081.10.375851
MA0083.10.96604
MA0084.11.54225
MA0087.10.922929
MA0088.10.064239
MA0089.10
MA0090.11.03628
MA0091.10.447561
MA0092.10.401504
MA0093.10.289361
MA0095.10
MA0098.10
MA0100.10.519598
MA0101.10.362124
MA0103.10.307078
MA0105.10.823589
MA0106.10.626997
MA0107.10.814533
MA0108.20.710846
MA0109.10
MA0111.11.06639
MA0113.10.598933
MA0114.10.222763
MA0115.10.969632
MA0116.10.27152
MA0117.10.937363
MA0119.10.951747
MA0122.10.957212
MA0124.11.16127
MA0125.11.0872
MA0130.10
MA0131.10.683521
MA0132.10
MA0133.10
MA0135.11.00325
MA0136.10.550755
MA0139.10.506952
MA0140.10.519484
MA0141.10.325895
MA0142.10.761136
MA0143.10.615203
MA0144.10.640537
MA0145.10.246409
MA0146.10.198184
MA0147.10.236889
MA0148.11.14345
MA0149.10.367458
MA0062.20.137653
MA0035.20.524137
MA0039.20.00106576
MA0138.20.675599
MA0002.21.56981
MA0137.20.863775
MA0104.20.18504
MA0047.20.576767
MA0112.20.0701537
MA0065.20.0704227
MA0150.11.07698
MA0151.10
MA0152.10.576873
MA0153.11.01988
MA0154.10.100744
MA0155.10.0804339
MA0156.10.843735
MA0157.10.729116
MA0158.10
MA0159.10.688775
MA0160.10.453546
MA0161.10
MA0162.10.0211019
MA0163.10.0186439
MA0164.10.551114
MA0080.20.302064
MA0018.20.560731
MA0099.20.669311
MA0079.21.52682e-06
MA0102.21.59466
MA0258.10.210437
MA0259.10.227035
MA0442.10
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