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MCL coexpression mm9:1737: Difference between revisions

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{{MCL_coexpression_mm9
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sodium channel activity;0.0157234427217444;20277!GO:0005272;sodium channel activity;0.0292006793403824;20277!GO:0050909;sensory perception of taste;0.0310725177596377;20277!GO:0031402;sodium ion binding;0.0310725177596377;20277!GO:0015276;ligand-gated ion channel activity;0.0310725177596377;20277!GO:0022834;ligand-gated channel activity;0.0310725177596377;20277!GO:0006814;sodium ion transport;0.0359392976497014;20277!GO:0031420;alkali metal ion binding;0.0496973100312277;20277!|ontology_enrichment_celltype=|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0001008!3.08e-14!19;UBERON:0006554!1.44e-13!18;UBERON:0002113!1.26e-10!14;UBERON:0003918!1.26e-10!14;UBERON:0011143!1.26e-10!14;UBERON:0005095!1.26e-10!14;UBERON:0007687!1.26e-10!14;UBERON:0005153!1.27e-10!17;UBERON:0002048!1.87e-08!14;UBERON:0000117!1.87e-08!14;UBERON:0000171!1.87e-08!14;UBERON:0000170!1.87e-08!14;UBERON:0005597!1.87e-08!14;UBERON:0000118!1.87e-08!14;UBERON:0005177!2.48e-08!79;UBERON:0005157!4.63e-08!20;UBERON:0000464!5.13e-08!57;UBERON:0000489!4.79e-07!21;UBERON:0005178!5.61e-07!17;UBERON:0005181!5.61e-07!17;UBERON:0002224!5.61e-07!17;UBERON:0000915!5.61e-07!17;UBERON:0008947!5.61e-07!17;UBERON:0003258!5.61e-07!17;UBERON:0002100!8.04e-07!90;UBERON:0003100!9.56e-07!11|tfbs_overrepresentation_for_novel_motifs=0.557864,1.02681,0.529553,0.603273,1.04755,0.618805,0.715644,0.300268,1.51246,0.115752,0.668936,0.702872,0.300533,0.728641,0.424775,0,0.930881,0.397593,1.41491,1.0421,0.489529,2.02858,0.727684,0.404661,0.537749,0.757752,1.38127,1.54767,0.456327,1.87618,0.626183,1.03545,1.02297,1.3018,1.08876,0.0566307,0.384813,0.699032,0.360612,0.328675,0.401916,0.631725,2.61647,0.426986,0.4934,0.591277,1.97509,1.58288,0.746467,2.02629,0.912738,0.786094,0.627649,1.18062,1.19842,0.73621,0.469329,0.689304,0.26467,0.734051,1.01481,0.796017,1.5593,0.901018,0.747985,0.943088,1.33705,1.68977,1.00999,1.54147,1.26875,0.30684,0.46305,1.23259,0.714607,1.27178,0.70455,0.835925,0.997094,0.494135,0.830212,0.948899,0.794502,0.293164,1.1148,0.0793594,0.0882907,0.227755,0.852952,1.85284,1.40768,1.11989,1.04863,0.412897,0.356133,0.3366,0.297538,1.05152,0.848095,0.20438,0.384901,1.03517,1.16282,0.913356,0.91226,0.631253,0.97421,0.653843,0.499439,0.491483,0.550229,1.16464,0.495367,0.674448,1.41481,0.399936,1.64321,0.607321,0.932233,1.75823,1.23809,0.879184,0.759676,0.834976,1.46955,1.00091,0.724289,1.04166,1.33551,0.416189,1.14546,0.595426,1.3055,0.750642,1.43666,0.143464,0.566955,0.633235,1.3869,2.2222,1.82084,1.34183,0.772375,1.04623,0.905521,0.632211,0.851091,2.18247,0.569503,0.408309,1.89099,0.416978,1.18223,0.908552,0.749664,1.26545,0.787153,1.95382,0.555203,0.566652,1.39653,1.11392,1.00137,0.547782,0.90208,0.741834,0.383572,0.701187,1.14345|tfbs_overrepresentation_jaspar=MA0003.1;0.989123,MA0004.1;0.603793,MA0006.1;0.419915,MA0007.1;0.587678,MA0009.1;1.06266,MA0014.1;0.0502051,MA0017.1;0.449113,MA0019.1;0.874061,MA0024.1;1.01759,MA0025.1;1.30092,MA0027.1;2.72141,MA0028.1;0.43138,MA0029.1;0.995171,MA0030.1;1.00195,MA0031.1;0.965177,MA0038.1;0.757669,MA0040.1;1.07552,MA0041.1;0.522007,MA0042.1;0.507715,MA0043.1;1.1618,MA0046.1;1.09955,MA0048.1;0.593503,MA0050.1;0.645342,MA0051.1;0.767098,MA0052.1;1.08379,MA0055.1;0.28842,MA0056.1;0,MA0057.1;0.192781,MA0058.1;0.50032,MA0059.1;0.513699,MA0060.1;0.330907,MA0061.1;0.364227,MA0063.1;0,MA0066.1;0.746072,MA0067.1;1.41352,MA0068.1;0.197245,MA0069.1;1.08414,MA0070.1;1.07418,MA0071.1;0.644448,MA0072.1;1.06547,MA0073.1;0.000589538,MA0074.1;0.708108,MA0076.1;0.470037,MA0077.1;1.04318,MA0078.1;0.801834,MA0081.1;0.53877,MA0083.1;1.16099,MA0084.1;1.74401,MA0087.1;1.11687,MA0088.1;1.42769,MA0089.1;0,MA0090.1;0.566938,MA0091.1;0.617887,MA0092.1;0.567278,MA0093.1;0.440484,MA0095.1;0,MA0098.1;0,MA0100.1;0.695835,MA0101.1;0.523409,MA0103.1;2.03092,MA0105.1;0.248108,MA0106.1;0.809991,MA0107.1;0.454197,MA0108.2;2.07761,MA0109.1;0,MA0111.1;0.582193,MA0113.1;1.83629,MA0114.1;0.361633,MA0115.1;1.16466,MA0116.1;1.07655,MA0117.1;1.13165,MA0119.1;0.524046,MA0122.1;1.15196,MA0124.1;1.35963,MA0125.1;1.28445,MA0130.1;0,MA0131.1;0.869325,MA0132.1;0,MA0133.1;0,MA0135.1;1.19898,MA0136.1;0.729175,MA0139.1;0.8026,MA0140.1;0.695713,MA0141.1;2.10278,MA0142.1;0.950155,MA0143.1;0.797553,MA0144.1;0.365053,MA0145.1;1.48363,MA0146.1;0.475727,MA0147.1;0.378658,MA0148.1;0.621195,MA0149.1;0.529387,MA0062.2;0.254018,MA0035.2;0.700704,MA0039.2;1.8247,MA0138.2;0.861035,MA0002.2;1.47075,MA0137.2;0.479301,MA0104.2;0.315156,MA0047.2;0.75686,MA0112.2;0.47695,MA0065.2;0.158101,MA0150.1;1.43499,MA0151.1;0,MA0152.1;0.756973,MA0153.1;1.21594,MA0154.1;0.587595,MA0155.1;0.515751,MA0156.1;0.469089,MA0157.1;0.91689,MA0158.1;0,MA0159.1;0.389847,MA0160.1;0.624415,MA0161.1;0,MA0162.1;0.0699535,MA0163.1;0.0644585,MA0164.1;0.729558,MA0080.2;0.455167,MA0018.2;0.739807,MA0099.2;0.854449,MA0079.2;0.0167818,MA0102.2;1.79669,MA0258.1;2.47863,MA0259.1;0.960816,MA0442.1;0}}
|coexpression_dpi_cluster_scores_mean=0,0.0260008064764304,0.0325725532583352,0.0410911336588208,0.0352701044070988,0.0134795900873983,0.0906108873480862,0,0,0,0,0,0,0,0.0249731817189904,0,0,0,0,0,0.608513803175214,0,0,0.085934328712328,0.0358785949507481,0.0394137452631456,0.0311134791836162,0.031124434442538,0.027978765328963,0,0.0761738509080614,0,0,0,0.054208151729089,0.0133571877744951,0.0322750284291383,0,0,0,0,0,0,0,0,0,0,0.0485651827914813,0.0488842528654776,0.107066998829803,0.0328200867908242,0,0,0,0,0,0,0.0361210508241096,0.0160037586108983,0.073761969269196,0,0,0,0,0,0,0.0227619479210974,0.0282409176368606,0,0,0,0,0.049110994372884,0.0100365579766666,0,0,0,0.0197546727344704,0,0.0215211194716882,0.0076037647116125,0,0.0213865357559922,0,0.0123506615380358,0,0.0448862478551964,0.0296923740634674,0.00634034871648942,0.0126557240951126,0.150803101987335,0,0.114105910599085,0.0836307336510484,0.0434850182672522,0.0321553251912308,0.398440725975172,0,0,0,0.0851175428616658,0,0,0,0.085428811772192,0.0748368086267828,0.0355375622983962,0.480429846087254,0.0200008604846734,0.0360654716465999,0.090643479936628,0.023086518062959,0.126418314715876,0.0350793141991126,0.0463481376694343,0,0.40978530076587,0.0337946722277335,0,0.0130237960169016,0.017331858075575,0,0.481516857445562,0.0880774217569184,0.108793040314252,0.0914562831581084,0,0,0,0,0.0327217486108414,0.0102810109601085,0.0537565768240783,0.0358776601979242,0,0,0.134216297658152,0.108159213370813,0.269116713231886,0.245678389808814,0.0106249462058222,0,0,0.044592955917239,0,0.0209411524840382,0.0226994406054172,0.121658958462109,0,0,0,0,0.0213093819849198,0.173766859645667,0.256380192636638,0.18805824652016,0,0,0,0.0163505044705796,0.0183000524034538,0,0.0521254214668711,0.0288231687630738,0.0358182816931736,0,0.0619277306385906,0.0677639096233399,0.04808384960991,0,0.013541334992983,0.0118520798714393,0.0488581388727951,0.0218768402956055,0.0636489035188164,0.0162557204018725,0.0440654318902148,0.0368758805175546,0.0703750538870781,0.0181388258857388,0.0210571820151998,0,0.0668411228510358,0.116660115600562,0.0579649580914,0.151973418556281,0.169952031587065,0.191485877241613,0.199651783678296,0,0.229139197409754,0.281117879177566,0.57199868884062,0.635985917304879,0.717786140273932,0.888239978268319,0.905887014884102,0.900537104470382,1.03701406877872,1.01446669720847,1.06194019222328,0.969600860995295,0.119407552463976,0,0.0155868231842077,0,0.0412885525989524,0.0187667550123388,0,0.171744987787963,0.0718741422974565,0,0,0.193819966653502,0.11523298407322,0.0586830503899422,0.0634615548616134,0.0341956312905688,1.1781829075045,0.0301445242965515,0.264330379466554,0.294595156226572,0.329715498860312,0.640366521955661,0.730676269014383,1.10234882322752,0.837655996149198,0.911194288426935,0.787425523885682,1.00880556730928,0.954295049766502,1.0724344673472,0,0,0.758992887426416,0.677712821131294,0.0387984460170794,0.0288812819939434,0,0.0391070614640153,0,0,0,0,0,0,0,0,0,0.0242016882738972,0.151500548677623,0.109840702731166,0.152827673303443,0.318479051897896,0.568136483373722,0.12401331374538,0.274884166175356,0.253165187039183,0.317673258696705,0.279484639285362,0.38563275033919,0.416091032942114,0.451157469587162,0.248150595426532,0.125055913261226,0.342542238949228,0.674786260481456,0.0518953794366691,0.0211327582219069,0.0337356961586166,0.060747152002126,0.0692679193773126,0.143329362028714,0.305283614596414,0.433744897012657,0.688519807029905,0.688151232020032,0.474913071734891,0.567787464263541,0.44050688061865,0.519470636774394,0.593032079743112,0.0767920182593272,0,0,0.0162973202140673,0.0273687762545886,0.0149902231516349,0,0,0,0.0113772712432778,0.0112437142554111,0.49847963339204,0,0.107501619245835,0.0644769182892533,0.247161359370522,0.297365825708372,0.593301250034018,0.557471245741971,0.588420676146484,0.483699310370286,1.55218135829465,0,0,0.0132993620172289,0.0594017069575522,0,0.0524048105252285,0.0366266161482308,0.0413650784078528,0.0576169494406756,0,0.0219851961141404,0.18851467281723,0.0616296730222441,0.0162278165181211,0.010609602440298,0.0531667377587488,0.0290618298722134,0.0366039826580792,0.0119648837323888,0.0243308615716135,0.0127582937957152,0.0326432700856487,0.0458226486487763,0.0159577956612578,0.0470488866762439,0.475291124581951,0.0648535998397928,0.034097145273613,0.0874827651720212,0.656941116582118,0.814461453001744,0.604446993404201,0.625369522075604,0.255109546345256,0.038889094328237,0,0.0393399747288678,0,0,0,0,0.0322928392524436,0.0649232710200672,0,0.00857708231151888,0,0.0136916169798492,0.0853784456998812,0.0330586016152326,0.0938880948631526,0.301224408673341,0.281435613644705,0.283835580753517,0.236982643685826,0.18987986497505,0.219696804417139,0.259607560939526,0.237545483398823,0.237915835995539,0.161213453247308,0.223251498729498,0.269539602619901,0.20881211870586,0.229421852696466,0.339322489824863,0.190144507968513,0.195888336138224,0.283600277031105,0.252068122131321,0.237757760903583,0.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|gostat_on_MCL_coexpression=GO:0015280;amiloride-sensitive sodium channel activity;0.0157234427217444;20277!GO:0005272;sodium channel activity;0.0292006793403824;20277!GO:0050909;sensory perception of taste;0.0310725177596377;20277!GO:0031402;sodium ion binding;0.0310725177596377;20277!GO:0015276;ligand-gated ion channel activity;0.0310725177596377;20277!GO:0022834;ligand-gated channel activity;0.0310725177596377;20277!GO:0006814;sodium ion transport;0.0359392976497014;20277!GO:0031420;alkali metal ion binding;0.0496973100312277;20277!
}}

Latest revision as of 17:25, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr1:120524563..120524591,+p2@Tfcp2l1
Mm9::chr1:120524622..120524637,+p@chr1:120524622..120524637
+
Mm9::chr7:129008545..129008557,+p3@Scnn1b
Mm9::chr7:129008565..129008579,+p2@Scnn1b
Mm9::chr7:129008584..129008607,+p1@Scnn1b


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0015280amiloride-sensitive sodium channel activity0.0157234427217444
GO:0005272sodium channel activity0.0292006793403824
GO:0050909sensory perception of taste0.0310725177596377
GO:0031402sodium ion binding0.0310725177596377
GO:0015276ligand-gated ion channel activity0.0310725177596377
GO:0022834ligand-gated channel activity0.0310725177596377
GO:0006814sodium ion transport0.0359392976497014
GO:0031420alkali metal ion binding0.0496973100312277



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
renal system3.08e-1419
urinary system structure1.44e-1318
kidney1.26e-1014
kidney mesenchyme1.26e-1014
upper urinary tract1.26e-1014
kidney rudiment1.26e-1014
kidney field1.26e-1014
epithelial bud1.27e-1017
lung1.87e-0814
respiratory tube1.87e-0814
respiration organ1.87e-0814
pair of lungs1.87e-0814
lung primordium1.87e-0814
lung bud1.87e-0814
trunk region element2.48e-0879
epithelial fold4.63e-0820
anatomical space5.13e-0857
cavitated compound organ4.79e-0721
thoracic cavity element5.61e-0717
thoracic segment organ5.61e-0717
thoracic cavity5.61e-0717
thoracic segment of trunk5.61e-0717
respiratory primordium5.61e-0717
endoderm of foregut5.61e-0717
trunk8.04e-0790
female organism9.56e-0711


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.989123
MA0004.10.603793
MA0006.10.419915
MA0007.10.587678
MA0009.11.06266
MA0014.10.0502051
MA0017.10.449113
MA0019.10.874061
MA0024.11.01759
MA0025.11.30092
MA0027.12.72141
MA0028.10.43138
MA0029.10.995171
MA0030.11.00195
MA0031.10.965177
MA0038.10.757669
MA0040.11.07552
MA0041.10.522007
MA0042.10.507715
MA0043.11.1618
MA0046.11.09955
MA0048.10.593503
MA0050.10.645342
MA0051.10.767098
MA0052.11.08379
MA0055.10.28842
MA0056.10
MA0057.10.192781
MA0058.10.50032
MA0059.10.513699
MA0060.10.330907
MA0061.10.364227
MA0063.10
MA0066.10.746072
MA0067.11.41352
MA0068.10.197245
MA0069.11.08414
MA0070.11.07418
MA0071.10.644448
MA0072.11.06547
MA0073.10.000589538
MA0074.10.708108
MA0076.10.470037
MA0077.11.04318
MA0078.10.801834
MA0081.10.53877
MA0083.11.16099
MA0084.11.74401
MA0087.11.11687
MA0088.11.42769
MA0089.10
MA0090.10.566938
MA0091.10.617887
MA0092.10.567278
MA0093.10.440484
MA0095.10
MA0098.10
MA0100.10.695835
MA0101.10.523409
MA0103.12.03092
MA0105.10.248108
MA0106.10.809991
MA0107.10.454197
MA0108.22.07761
MA0109.10
MA0111.10.582193
MA0113.11.83629
MA0114.10.361633
MA0115.11.16466
MA0116.11.07655
MA0117.11.13165
MA0119.10.524046
MA0122.11.15196
MA0124.11.35963
MA0125.11.28445
MA0130.10
MA0131.10.869325
MA0132.10
MA0133.10
MA0135.11.19898
MA0136.10.729175
MA0139.10.8026
MA0140.10.695713
MA0141.12.10278
MA0142.10.950155
MA0143.10.797553
MA0144.10.365053
MA0145.11.48363
MA0146.10.475727
MA0147.10.378658
MA0148.10.621195
MA0149.10.529387
MA0062.20.254018
MA0035.20.700704
MA0039.21.8247
MA0138.20.861035
MA0002.21.47075
MA0137.20.479301
MA0104.20.315156
MA0047.20.75686
MA0112.20.47695
MA0065.20.158101
MA0150.11.43499
MA0151.10
MA0152.10.756973
MA0153.11.21594
MA0154.10.587595
MA0155.10.515751
MA0156.10.469089
MA0157.10.91689
MA0158.10
MA0159.10.389847
MA0160.10.624415
MA0161.10
MA0162.10.0699535
MA0163.10.0644585
MA0164.10.729558
MA0080.20.455167
MA0018.20.739807
MA0099.20.854449
MA0079.20.0167818
MA0102.21.79669
MA0258.12.47863
MA0259.10.960816
MA0442.10
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