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|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=1
|data_phase=2
|datafreeze_phase=1
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr21:39870339..39870443,-!p1@ERG!2.14!136.86!ERG;;chr8:55370487..55370503,+!p1@SOX17!2.06!114.05!SOX17;;chr20:62680984..62680999,-!p1@SOX18!1.98!122.42!SOX18;;chr8:10588010..10588030,-!p1@SOX7!1.95!88.64!SOX7;;chr1:214161272..214161322,+!p1@PROX1!1.86!99.76!PROX1;;chr22:19748231..19748317,+!p1@TBX1!1.73!52.41!TBX1;;chr17:6926362..6926377,+!p1@BCL6B!1.68!46.34!BCL6B;;chr3:12330560..12330579,+!p1@PPARG!1.63!47.79!PPARG;;chr18:53068911..53068935,-!p4@TCF4!1.57!40.57!TCF4;;chr17:45933057..45933064,-!p3@SP6!1.50!30.89!SP6;;chr10:94449703..94449718,+!p1@HHEX!1.41!93.84!HHEX;;chr12:96588368..96588394,+!p3@ELK3!1.38!59.91!ELK3;;chr2:177053386..177053402,+!p1@HOXD1!1.28!18.19!HOXD1;;chr16:85932760..85932775,+!p1@IRF8!1.27!17.61!IRF8;;chr8:80679993..80680011,-!p1@HEY1!1.24!23.39!HEY1;;chr17:46682321..46682362,-!p1@HOXB6!1.21!15.16!HOXB6;;chr18:52988979..52988993,-!p18@TCF4!1.15!13.28!TCF4;;chr17:46688334..46688385,-!p1@HOXB7!1.14!18.48!HOXB7;;chr18:53089538..53089578,-!p14@TCF4!1.14!12.85!TCF4;;chr7:26191809..26191890,+!p1@NFE2L3!1.13!61.21!NFE2L3;;chr22:41697497..41697515,+!p2@ZC3H7B!1.08!30.32!ZC3H7B;;chr16:86600426..86600441,+!p1@FOXC2!1.08!27.43!FOXC2;;chr2:176994408..176994492,+!p1@HOXD8!1.06!10.39!HOXD8;;chr18:52989001..52989030,-!p10@TCF4!1.05!11.26!TCF4;;chr1:47695003..47695042,-!p2@TAL1!1.05!10.11!TAL1;;chr18:22932080..22932170,-!p1@ZNF521!1.03!42.01!ZNF521;;chr7:27205106..27205134,-!p2@HOXA9!1.01!9.24!HOXA9;;chr6:85474299..85474324,-!p1@TBX18!1.00!16.31!TBX18;;chr3:128206762..128206781,-!p2@GATA2!0.99!56.30!GATA2;;chr18:52989565..52989623,-!p9@TCF4!0.98!10.97!TCF4;;chr2:176981499..176981522,+!p2@HOXD10!0.98!8.52!HOXD10;;chr18:53177984..53178004,-!p17@TCF4!0.97!8.37!TCF4;;chr19:46801639..46801699,+!p1@HIF3A!0.97!8.37!HIF3A;;chr11:65430554..65430579,-!p3@RELA!0.93!19.63!RELA;;chr10:31288398..31288455,-!p2@ZNF438!0.92!8.52!ZNF438;;chrY:21906594..21906622,-!p1@KDM5D!0.91!7.22!KDM5D;;chr18:52989031..52989079,-!p2@TCF4!0.90!17.04!TCF4;;chr11:128563948..128564003,+!p1@FLI1!0.89!84.74!FLI1;;chr10:31288370..31288393,-!p3@ZNF438!0.89!6.79!ZNF438;;chr7:27196267..27196311,-!p1@HOXA7!0.89!6.79!HOXA7;;chr22:19746969..19746987,+!p2@TBX1!0.89!6.79!TBX1;;chr18:52988952..52988965,-!p23@TCF4!0.89!6.79!TCF4;;chr4:146403912..146403972,+!p5@SMAD1!0.88!8.66!SMAD1;;chr14:74256787..74256858,-!p6@C14orf43!0.86!6.21!C14orf43;;chr1:6479968..6479986,-!p1@HES2!0.86!6.21!HES2;;chr8:106330656..106330684,+!p1@ZFPM2!0.85!16.89!ZFPM2;;chr14:35872962..35873025,-!p3@NFKBIA!0.85!16.02!NFKBIA;;chr3:101546827..101546847,+!p2@NFKBIZ!0.83!8.23!NFKBIZ;;chr22:38598086..38598105,+!p1@MAFF!0.81!63.09!MAFF;;chr6:21597765..21597779,+!p2@SOX4!0.81!47.21!SOX4;;chr2:231280954..231280965,+!p2@SP100!0.81!10.39!SP100;;chr4:185395633..185395651,-!p2@IRF2!0.81!9.10!IRF2;;chr12:80084137..80084165,-!p10@PAWR!0.80!7.07!PAWR;;chr22:41697484..41697496,+!p3@ZC3H7B!0.80!6.93!ZC3H7B;;chr7:27192185..27192209,-!p1@HOXA3!0.80!5.34!HOXA3;;chr22:38597987..38598021,+!p2@MAFF!0.79!33.93!MAFF;;chr10:94449675..94449694,+!p2@HHEX!0.79!14.73!HHEX;;chr20:50721803..50721857,-!p2@ZFP64!0.79!8.52!ZFP64;;chr6:85473156..85473210,-!p2@TBX18!0.78!6.21!TBX18;;chr7:27205136..27205164,-!p1@HOXA9!0.77!4.91!HOXA9;;chr17:46690839..46690884,-!p1@HOXB8!0.77!4.91!HOXB8;;chr1:23885981..23886002,-!p1@ID3!0.76!920.34!ID3;;chr20:30193083..30193098,+!p1@ID1!0.76!421.69!ID1;;chr10:63809013..63809041,+!p3@ARID5B!0.76!29.16!ARID5B;;chr8:80680024..80680046,-!p2@HEY1!0.76!5.49!HEY1;;chr19:13213399..13213414,-!p6@LYL1!0.75!4.62!LYL1;;chr2:46524537..46524553,+!p1@EPAS1!0.73!486.08!EPAS1;;chr1:209979467..209979494,-!p1@IRF6!0.73!5.05!IRF6;;chr6:21593973..21593988,+!p1@SOX4!0.72!173.82!SOX4;;chr4:103422499..103422632,+!p1@NFKB1!0.72!99.18!NFKB1;;chr19:13213511..13213545,-!p2@LYL1!0.72!4.62!LYL1;;chr5:131826457..131826514,-!p1@IRF1!0.71!183.92!IRF1;;chr19:42636586..42636607,-!p1@POU2F2!0.71!12.42!POU2F2;;chr2:85980951..85981004,+!p1@ATOH8!0.71!7.07!ATOH8;;chr18:53089493..53089517,-!p15@TCF4!0.71!4.19!TCF4;;chr15:96874012..96874042,+!p2@NR2F2!0.70!40.57!NR2F2;;chr10:104154246..104154347,+!p3@NFKB2!0.70!27.43!NFKB2;;chr4:4861385..4861398,+!p1@MSX1!0.70!13.14!MSX1;;chr13:37494365..37494381,-!p1@SMAD9!0.70!7.51!SMAD9;;chr10:104155659..104155676,+!p4@NFKB2!0.70!5.20!NFKB2;;chr9:16705069..16705086,-!p3@BNC2!0.70!4.04!BNC2;;chr14:35873947..35873965,-!p1@NFKBIA!0.69!286.86!NFKBIA;;chr8:48650715..48650735,-!p1@CEBPD!0.68!559.56!CEBPD;;chr15:96873984..96873999,+!p3@NR2F2!0.68!32.05!NR2F2;;chr10:104155480..104155534,+!p2@NFKB2!0.68!28.15!NFKB2;;chr20:50159198..50159299,-!p1@NFATC2!0.68!5.77!NFATC2;;chr20:48599506..48599526,+!p1@SNAI1!0.67!27.29!SNAI1;;chr4:146402843..146402864,+!p3@SMAD1!0.67!7.94!SMAD1;;chr6:34204921..34204939,+!p3@HMGA1!0.66!125.89!HMGA1;;chr10:35484804..35484902,+!p2@CREM!0.66!15.45!CREM;;chr3:12329397..12329433,+!p2@PPARG!0.66!9.10!PPARG;;chr4:146404119..146404158,+!p9@SMAD1!0.66!3.61!SMAD1;;chr12:80084018..80084035,-!p17@PAWR!0.66!3.61!PAWR;;chr5:92918919..92918942,+!p1@NR2F1!0.65!17.76!NR2F1;;chr2:46524897..46524911,+!p2@EPAS1!0.65!10.97!EPAS1;;chr12:80084167..80084197,-!p5@PAWR!0.65!9.10!PAWR;;chr7:27224911..27224922,-!p5@HOXA11!0.65!3.46!HOXA11;;chr18:22932004..22932021,-!p2@ZNF521!0.65!3.46!ZNF521;;chr6:130339710..130339745,+!p1@L3MBTL3!0.64!31.04!L3MBTL3;;chr4:185395590..185395627,-!p3@IRF2!0.64!4.33!IRF2;;chr1:47697539..47697573,-!p3@TAL1!0.64!3.32!TAL1;;chr10:94451574..94451587,+!p6@HHEX!0.64!3.32!HHEX;;chr2:28615716..28615733,+!p1@FOSL2!0.63!183.35!FOSL2;;chr11:128392273..128392308,-!p2@ETS1!0.63!15.88!ETS1;;chr6:44233252..44233296,-!p1@NFKBIE!0.62!37.54!NFKBIE;;chr12:11802753..11802834,+!p2@ETV6!0.62!18.19!ETV6;;chr19:49865646..49865718,-!p1@TEAD2!0.61!31.18!TEAD2;;chr8:55370720..55370733,+!p2@SOX17!0.61!3.03!SOX17;;chr4:103446567..103446592,+!p15@NFKB1!0.61!3.03!NFKB1;;chr18:53068940..53068951,-!p21@TCF4!0.61!3.03!TCF4;;chr18:53089453..53089482,-!p11@TCF4!0.61!3.03!TCF4;;chr22:41697520..41697613,+!p1@ZC3H7B!0.60!203.41!ZC3H7B;;chr9:14314566..14314618,-!p1@NFIB!0.60!43.60!NFIB;;chr18:53089521..53089533,-!p22@TCF4!0.59!2.89!TCF4;;chr18:53177899..53177918,-!p33@TCF4!0.59!2.89!TCF4;;chr17:3571863..3571881,-!p1@TAX1BP3!0.58!248.89!TAX1BP3;;chr6:126240380..126240430,+!p2@NCOA7!0.58!8.37!NCOA7;;chr18:53257001..53257015,-!p5@TCF4!0.57!5.20!TCF4;;chr3:71355163..71355209,-!p5@FOXP1!0.57!4.04!FOXP1;;chr2:176987441..176987454,+!p1@HOXD9!0.57!2.74!HOXD9;;chr2:176987463..176987479,+!p2@HOXD9!0.57!2.74!HOXD9;;chr2:177001290..177001315,+!p1@HOXD3!0.57!2.74!HOXD3;;chr18:22931979..22931992,-!p3@ZNF521!0.57!2.74!ZNF521;;chr1:214161328..214161348,+!p2@PROX1!0.57!2.74!PROX1;;chr12:80084303..80084332,-!p1@PAWR!0.56!18.91!PAWR;;chr5:88179195..88179224,-!p3@MEF2C!0.56!4.62!MEF2C;;chr14:75988771..75988826,+!p1@BATF!0.56!3.75!BATF;;chr18:53068982..53068993,-!p20@TCF4!0.56!2.60!TCF4;;chr5:71803177..71803255,-!p1@ZNF366!0.56!2.60!ZNF366;;chr7:27195867..27195893,-!p3@HOXA7!0.56!2.60!HOXA7;;chr15:90544532..90544563,+!p1@ZNF710!0.55!5.92!ZNF710;;chr19:19303794..19303805,+!p5@RFXANK!0.55!3.03!RFXANK;;chr5:88178983..88179012,-!p1@MEF2C!0.54!24.25!MEF2C;;chr11:65430535..65430549,-!p4@RELA!0.54!3.03!RELA;;chr11:128457446..128457461,-!p4@ETS1!0.54!2.45!ETS1;;chr11:65429891..65429915,-!p7@RELA!0.54!2.45!RELA;;chr16:86600870..86600921,+!p2@FOXC2!0.54!2.45!FOXC2;;chr1:214161358..214161377,+!p3@PROX1!0.54!2.45!PROX1;;chr10:63809106..63809127,+!p1@ARID5B!0.53!41.14!ARID5B;;chr9:14314131..14314147,-!p2@NFIB!0.53!16.89!NFIB;;chr3:12329358..12329393,+!p3@PPARG!0.53!6.93!PPARG;;chr2:85981222..85981259,+!p2@ATOH8!0.53!4.48!ATOH8;;chr19:13213662..13213686,-!p1@LYL1!0.53!3.90!LYL1;;chr10:63808979..63808990,+!p8@ARID5B!0.53!2.74!ARID5B;;chr3:101568349..101568365,+!p1@NFKBIZ!0.52!159.24!NFKBIZ;;chr12:3069037..3069119,+!p2@TEAD4!0.52!9.82!TEAD4;;chr7:27224842..27224872,-!p1@HOXA11!0.52!2.31!HOXA11;;chr17:47892398..47892407,+!p2@KAT7!0.52!2.31!KAT7;;chr19:45252008..45252024,+!p2@BCL3!0.51!9.24!BCL3;;chr9:14083467..14083483,-!p4@NFIB!0.51!6.64!NFIB;;chr9:14082760..14082775,-!p6@NFIB!0.51!4.19!NFIB;;chr2:85980919..85980942,+!p4@ATOH8!0.51!2.45!ATOH8;;chr15:96876966..96877017,+!p12@NR2F2!0.50!3.46!NR2F2;;chr1:37940170..37940190,+!p1@ZC3H12A!0.49!34.50!ZC3H12A;;chr1:161736140..161736151,+!p3@ATF6!0.49!8.23!ATF6;;chr15:96874145..96874166,+!p7@NR2F2!0.49!4.76!NR2F2;;chr11:65686802..65686818,+!p6@DRAP1!0.49!4.19!DRAP1;;chr19:57106647..57106686,+!p1@ZNF71!0.48!17.76!ZNF71;;chr9:35732647..35732678,+!p2@CREB3!0.48!14.87!CREB3;;chr15:96874216..96874236,+!p13@NR2F2!0.48!3.61!NR2F2;;chr15:83953397..83953425,-!p1@BNC1!0.48!2.45!BNC1;;chr18:53069219..53069253,-!p35@TCF4!0.48!2.02!TCF4;;chrY:2803415..2803468,+!p1@ZFY!0.48!2.02!ZFY;;chr22:19747040..19747054,+!p3@TBX1!0.48!2.02!TBX1;;chr15:96873921..96873946,+!p1@NR2F2!0.47!75.50!NR2F2;;chr1:151032860..151032918,+!p1@MLLT11!0.47!31.18!MLLT11;;chr19:45504688..45504782,+!p1@RELB!0.47!15.59!RELB;;chr12:27485823..27485868,+!p2@ARNTL2!0.47!10.25!ARNTL2;;chr12:66218255..66218304,+!p3@HMGA2!0.47!6.64!HMGA2;;chr2:46524878..46524891,+!p3@EPAS1!0.47!4.04!EPAS1;;chr2:46602901..46602926,+!p7@EPAS1!0.47!2.89!EPAS1;;chr22:38598042..38598052,+!p4@MAFF!0.46!3.46!MAFF;;chr18:6414884..6414942,-!p1@L3MBTL4!0.46!2.60!L3MBTL4;;chr17:46688310..46688323,-!p4@HOXB7!0.46!1.88!HOXB7;;chr1:201979703..201979721,+!p2@ELF3!0.46!1.88!ELF3;;chr1:47696918..47696935,-!p6@TAL1!0.46!1.88!TAL1;;chr6:85474198..85474212,-!p3@TBX18!0.46!1.88!TBX18;;chr7:27190547..27190591,-!p1@HOXA6!0.46!1.88!HOXA6;;chr7:27205089..27205096,-!p4@HOXA9!0.46!1.88!HOXA9;;chr22:38598057..38598071,+!p3@MAFF!0.45!5.34!MAFF;;chr15:96873861..96873872,+!p9@NR2F2!0.45!4.62!NR2F2;;chr8:73921136..73921151,+!p2@TERF1!0.45!3.18!TERF1;;chr4:185395191..185395226,-!p4@IRF2!0.45!2.89!IRF2;;chr14:35872926..35872951,-!p4@NFKBIA!0.45!2.89!NFKBIA;;chr17:7590797..7590815,-!p1@TP53!0.44!109.43!TP53;;chr12:80085255..80085284,-!p9@PAWR!0.44!2.89!PAWR;;chr19:49864746..49864780,-!p2@TEAD2!0.44!2.74!TEAD2;;chr6:21597283..21597312,+!p7@SOX4!0.44!2.60!SOX4;;chr8:1063306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Line 45: Line 45:
|is_obsolete=
|is_obsolete=
|library_id=CNhs11936
|library_id=CNhs11936
|library_id_phase_based=1:CNhs11936
|library_id_phase_based=2:CNhs11936
|name=Lymphatic Endothelial cells response to VEGFC, 00hr00min, biol_rep1 (MM XIX - 1)
|name="Lymphatic Endothelial cells response to VEGFC, 00hr00min, biol_rep1 (MM XIX - 1)"
|namespace=FANTOM5
|namespace=FANTOM5
|part_of=
|part_of=
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Line 72: Line 72:
|sample_cell_line=
|sample_cell_line=
|sample_cell_lot=
|sample_cell_lot=
|sample_cell_type=endothelial cell, lymphatic
|sample_cell_type="endothelial cell, lymphatic"
|sample_collaboration=Michael Detmar (Swiss Federal Institute of Technology, ETH Zurich)
|sample_collaboration="Michael Detmar (Swiss Federal Institute of Technology, ETH Zurich)"
|sample_company=
|sample_company=
|sample_description=
|sample_description=

Revision as of 19:46, 27 November 2014


Name:"Lymphatic Endothelial cells response to VEGFC, 00hr00min, biol_rep1 (MM XIX - 1)"
Species:Human (Homo sapiens)
Library ID:CNhs11936
Sample type:time courses
Genomic View: UCSC
CAGEd-oPOSSUM:link
Additional information
Sample information
strainNA
tissuelymph node
dev stageNA
sexNA
ageNA
cell type"endothelial cell, lymphatic"
cell lineNA
companyNA
collaboration"Michael Detmar (Swiss Federal Institute of Technology, ETH Zurich)"
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typeNA
extraction protocol (Details)NA

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00004711
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11936 CAGE DRX008589 DRR009461
Accession ID Hg19

Library idBAMCTSS
CNhs11936 DRZ000886 DRZ002271
Download raw sequence, BAM & CTSS
Hg19
BAMCTSS
[{{{hg19bam}}} download][{{{hg19ctss}}} donwload]
Hg38
BAMCTSS
[{{{hg38bam}}} download][{{{hg38ctss}}} donwload]


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>dataNo results for this sample

Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: "CNhs11936This sample isn't target for the analysis

FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: "CNhs11936This sample isn't target for the analysis

de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: "CNhs11936


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0002139 (endothelial cell of vascular tree)
0000213 (lining cell)
0002078 (meso-epithelial cell)
0000215 (barrier cell)
0000255 (eukaryotic cell)
0000115 (endothelial cell)
0002138 (endothelial cell of lymphatic vessel)

UBERON: Anatomy
0000468 (multi-cellular organism)
0000055 (vessel)
0004111 (anatomical conduit)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0002049 (vasculature)
0007798 (vascular system)
0001473 (lymphatic vessel)
0002465 (lymphoid system)
0004535 (cardiovascular system)
0004536 (lymph vasculature)
0006558 (lymphatic part of lymphoid system)
0002193 (hemolymphoid system)
0002405 (immune system)
0001009 (circulatory system)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000046 (human endothelial cell sample)
0000001 (sample)
0000350 (experimentally modified sample)
0000049 (human lymphatic endothelial cell sample)
0000341 (Vegfc treatment sample)
0000344 (0 minute sample)
0000410 (human Lymphatic Endothelial cells 0min after VEGFC treatment sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000222 (mesodermal cell)
CL:0005022 (vascular lymphangioblast)