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MCL coexpression mm9:1642: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0035091;phosphoinositide binding;0.0112294586646708;66895,13636!GO:0005543;phospholipid binding;0.0112294586646708;66895,13636!GO:0050790;regulation of catalytic activity;0.0112294586646708;13636,54720!GO:0048013;ephrin receptor signaling pathway;0.0112294586646708;13636!GO:0043666;regulation of phosphoprotein phosphatase activity;0.0112294586646708;54720!GO:0065009;regulation of a molecular function;0.0112294586646708;13636,54720!GO:0008289;lipid binding;0.0126774394364876;66895,13636!GO:0019722;calcium-mediated signaling;0.0340461036786531;54720!GO:0050770;regulation of axonogenesis;0.0432118247404294;13636!GO:0000187;activation of MAPK activity;0.0464345050491006;13636!GO:0043406;positive regulation of MAP kinase activity;0.0464345050491006;13636!GO:0050767;regulation of neurogenesis;0.0464345050491006;13636!GO:0007242;intracellular signaling cascade;0.0464345050491006;13636,54720!GO:0007154;cell communication;0.0464345050491006;66895,13636,54720!GO:0043405;regulation of MAP kinase activity;0.0464345050491006;13636!GO:0048741;skeletal muscle fiber development;0.0464345050491006;54720!GO:0048747;muscle fiber development;0.0464345050491006;54720!GO:0048468;cell development;0.0464345050491006;13636,54720!
|gostat_on_MCL_coexpression=GO:0035091;phosphoinositide binding;0.0112294586646708;66895,13636!GO:0005543;phospholipid binding;0.0112294586646708;66895,13636!GO:0050790;regulation of catalytic activity;0.0112294586646708;13636,54720!GO:0048013;ephrin receptor signaling pathway;0.0112294586646708;13636!GO:0043666;regulation of phosphoprotein phosphatase activity;0.0112294586646708;54720!GO:0065009;regulation of a molecular function;0.0112294586646708;13636,54720!GO:0008289;lipid binding;0.0126774394364876;66895,13636!GO:0019722;calcium-mediated signaling;0.0340461036786531;54720!GO:0050770;regulation of axonogenesis;0.0432118247404294;13636!GO:0000187;activation of MAPK activity;0.0464345050491006;13636!GO:0043406;positive regulation of MAP kinase activity;0.0464345050491006;13636!GO:0050767;regulation of neurogenesis;0.0464345050491006;13636!GO:0007242;intracellular signaling cascade;0.0464345050491006;13636,54720!GO:0007154;cell communication;0.0464345050491006;66895,13636,54720!GO:0043405;regulation of MAP kinase activity;0.0464345050491006;13636!GO:0048741;skeletal muscle fiber development;0.0464345050491006;54720!GO:0048747;muscle fiber development;0.0464345050491006;54720!GO:0048468;cell development;0.0464345050491006;13636,54720!
|ontology_enrichment_celltype=CL:0000066!1.92e-07!25
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004119!5.83e-15!118;UBERON:0000925!5.83e-15!118;UBERON:0006595!5.83e-15!118;UBERON:0001007!2.17e-14!116;UBERON:0001555!2.17e-14!116;UBERON:0007026!2.17e-14!116;UBERON:0004921!1.29e-13!114;UBERON:0000160!3.13e-13!31;UBERON:0005409!1.22e-11!47;UBERON:0009569!2.53e-11!66;UBERON:0005177!4.81e-10!79;UBERON:0000344!1.78e-07!15;UBERON:0002048!1.85e-07!14;UBERON:0000117!1.85e-07!14;UBERON:0000171!1.85e-07!14;UBERON:0000170!1.85e-07!14;UBERON:0005597!1.85e-07!14;UBERON:0000118!1.85e-07!14;UBERON:0005178!2.77e-07!17;UBERON:0005181!2.77e-07!17;UBERON:0002224!2.77e-07!17;UBERON:0000915!2.77e-07!17;UBERON:0008947!2.77e-07!17;UBERON:0003258!2.77e-07!17;UBERON:0000466!5.26e-07!79;UBERON:0005153!7.21e-07!17;UBERON:0001242!9.62e-07!13;UBERON:0000060!9.62e-07!13;UBERON:0001262!9.62e-07!13;UBERON:0004786!9.62e-07!13
}}
}}

Revision as of 17:12, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr13:34744542..34744557,-p1@1300014I06Rik
Mm9::chr16:92400312..92400328,-p1@Rcan1
Mm9::chr3:89083505..89083516,-p3@Efna1
Mm9::chr3:89083524..89083549,-p1@Efna1
Mm9::chr3:89083555..89083569,-p2@Efna1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0035091phosphoinositide binding0.0112294586646708
GO:0005543phospholipid binding0.0112294586646708
GO:0050790regulation of catalytic activity0.0112294586646708
GO:0048013ephrin receptor signaling pathway0.0112294586646708
GO:0043666regulation of phosphoprotein phosphatase activity0.0112294586646708
GO:0065009regulation of a molecular function0.0112294586646708
GO:0008289lipid binding0.0126774394364876
GO:0019722calcium-mediated signaling0.0340461036786531
GO:0050770regulation of axonogenesis0.0432118247404294
GO:0000187activation of MAPK activity0.0464345050491006
GO:0043406positive regulation of MAP kinase activity0.0464345050491006
GO:0050767regulation of neurogenesis0.0464345050491006
GO:0007242intracellular signaling cascade0.0464345050491006
GO:0007154cell communication0.0464345050491006
GO:0043405regulation of MAP kinase activity0.0464345050491006
GO:0048741skeletal muscle fiber development0.0464345050491006
GO:0048747muscle fiber development0.0464345050491006
GO:0048468cell development0.0464345050491006



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
epithelial cell1.92e-0725

Uber Anatomy
Ontology termp-valuen
endoderm-derived structure5.83e-15118
endoderm5.83e-15118
presumptive endoderm5.83e-15118
digestive system2.17e-14116
digestive tract2.17e-14116
primitive gut2.17e-14116
subdivision of digestive tract1.29e-13114
intestine3.13e-1331
gastrointestinal system1.22e-1147
subdivision of trunk2.53e-1166
trunk region element4.81e-1079
mucosa1.78e-0715
lung1.85e-0714
respiratory tube1.85e-0714
respiration organ1.85e-0714
pair of lungs1.85e-0714
lung primordium1.85e-0714
lung bud1.85e-0714
thoracic cavity element2.77e-0717
thoracic segment organ2.77e-0717
thoracic cavity2.77e-0717
thoracic segment of trunk2.77e-0717
respiratory primordium2.77e-0717
endoderm of foregut2.77e-0717
immaterial anatomical entity5.26e-0779
epithelial bud7.21e-0717
intestinal mucosa9.62e-0713
anatomical wall9.62e-0713
wall of intestine9.62e-0713
gastrointestinal system mucosa9.62e-0713


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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