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MCL coexpression mm9:1920: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0048003;antigen processing and presentation of lipid antigen via MHC class Ib;0.0176731013834793;11776!GO:0048007;antigen processing and presentation, exogenous lipid antigen via MHC class Ib;0.0176731013834793;11776!GO:0002475;antigen processing and presentation via MHC class Ib;0.0176731013834793;11776!GO:0051136;regulation of NK T cell differentiation;0.0176731013834793;11776!GO:0001865;NK T cell differentiation;0.0176731013834793;11776!GO:0051138;positive regulation of NK T cell differentiation;0.0176731013834793;11776!GO:0003841;1-acylglycerol-3-phosphate O-acyltransferase activity;0.0340698345234604;55979!GO:0016411;acylglycerol O-acyltransferase activity;0.0430463304984218;55979!GO:0046632;alpha-beta T cell differentiation;0.0484853132184813;11776!GO:0019884;antigen processing and presentation of exogenous antigen;0.0484853132184813;11776!GO:0032313;regulation of Rab GTPase activity;0.0484853132184813;67231!GO:0032483;regulation of Rab protein signal transduction;0.0484853132184813;67231!GO:0032482;Rab protein signal transduction;0.0484853132184813;67231!GO:0008374;O-acyltransferase activity;0.0484853132184813;55979!GO:0046631;alpha-beta T cell activation;0.0484853132184813;11776!GO:0005097;Rab GTPase activator activity;0.0484853132184813;67231!GO:0005802;trans-Golgi network;0.0484853132184813;11776!GO:0032318;regulation of Ras GTPase activity;0.0484853132184813;67231!
|gostat_on_MCL_coexpression=GO:0048003;antigen processing and presentation of lipid antigen via MHC class Ib;0.0176731013834793;11776!GO:0048007;antigen processing and presentation, exogenous lipid antigen via MHC class Ib;0.0176731013834793;11776!GO:0002475;antigen processing and presentation via MHC class Ib;0.0176731013834793;11776!GO:0051136;regulation of NK T cell differentiation;0.0176731013834793;11776!GO:0001865;NK T cell differentiation;0.0176731013834793;11776!GO:0051138;positive regulation of NK T cell differentiation;0.0176731013834793;11776!GO:0003841;1-acylglycerol-3-phosphate O-acyltransferase activity;0.0340698345234604;55979!GO:0016411;acylglycerol O-acyltransferase activity;0.0430463304984218;55979!GO:0046632;alpha-beta T cell differentiation;0.0484853132184813;11776!GO:0019884;antigen processing and presentation of exogenous antigen;0.0484853132184813;11776!GO:0032313;regulation of Rab GTPase activity;0.0484853132184813;67231!GO:0032483;regulation of Rab protein signal transduction;0.0484853132184813;67231!GO:0032482;Rab protein signal transduction;0.0484853132184813;67231!GO:0008374;O-acyltransferase activity;0.0484853132184813;55979!GO:0046631;alpha-beta T cell activation;0.0484853132184813;11776!GO:0005097;Rab GTPase activator activity;0.0484853132184813;67231!GO:0005802;trans-Golgi network;0.0484853132184813;11776!GO:0032318;regulation of Ras GTPase activity;0.0484853132184813;67231!
|ontology_enrichment_celltype=CL:0000055!1.32e-07!49
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000073!9.27e-18!54;UBERON:0001017!7.25e-17!73;UBERON:0001016!9.69e-17!75;UBERON:0001049!1.17e-16!52;UBERON:0005068!1.17e-16!52;UBERON:0006241!1.17e-16!52;UBERON:0007135!1.17e-16!52;UBERON:0000955!5.84e-15!47;UBERON:0006238!5.84e-15!47;UBERON:0002616!1.45e-14!46;UBERON:0004121!3.38e-14!95;UBERON:0000924!3.38e-14!95;UBERON:0006601!3.38e-14!95;UBERON:0002020!2.71e-13!34;UBERON:0003080!3.05e-12!40;UBERON:0007023!4.39e-12!51;UBERON:0003528!6.83e-12!29;UBERON:0002791!6.83e-12!29;UBERON:0001893!6.83e-12!29;UBERON:0002780!1.12e-11!39;UBERON:0001890!1.12e-11!39;UBERON:0006240!1.12e-11!39;UBERON:0002346!1.50e-11!64;UBERON:0003075!1.50e-11!64;UBERON:0007284!1.50e-11!64;UBERON:0010371!1.28e-10!73;UBERON:0000956!8.35e-10!21;UBERON:0001869!8.35e-10!21;UBERON:0000203!8.35e-10!21;UBERON:0002619!5.10e-09!17;UBERON:0003056!1.89e-08!49;UBERON:0002021!1.07e-07!10;UBERON:0000411!1.07e-07!10;UBERON:0001950!1.07e-07!10
}}
}}

Revision as of 17:39, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:80204967..80205025,-p1@Ap3d1
Mm9::chr17:34742800..34742807,+p5@Agpat1
Mm9::chr2:152119567..152119597,+p2@Tbc1d20
Mm9::chr7:149088266..149088353,-p1@Tollip


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0048003antigen processing and presentation of lipid antigen via MHC class Ib0.0176731013834793
GO:0048007antigen processing and presentation, exogenous lipid antigen via MHC class Ib0.0176731013834793
GO:0002475antigen processing and presentation via MHC class Ib0.0176731013834793
GO:0051136regulation of NK T cell differentiation0.0176731013834793
GO:0001865NK T cell differentiation0.0176731013834793
GO:0051138positive regulation of NK T cell differentiation0.0176731013834793
GO:00038411-acylglycerol-3-phosphate O-acyltransferase activity0.0340698345234604
GO:0016411acylglycerol O-acyltransferase activity0.0430463304984218
GO:0046632alpha-beta T cell differentiation0.0484853132184813
GO:0019884antigen processing and presentation of exogenous antigen0.0484853132184813
GO:0032313regulation of Rab GTPase activity0.0484853132184813
GO:0032483regulation of Rab protein signal transduction0.0484853132184813
GO:0032482Rab protein signal transduction0.0484853132184813
GO:0008374O-acyltransferase activity0.0484853132184813
GO:0046631alpha-beta T cell activation0.0484853132184813
GO:0005097Rab GTPase activator activity0.0484853132184813
GO:0005802trans-Golgi network0.0484853132184813
GO:0032318regulation of Ras GTPase activity0.0484853132184813



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
non-terminally differentiated cell1.32e-0749

Uber Anatomy
Ontology termp-valuen
regional part of nervous system9.27e-1854
central nervous system7.25e-1773
nervous system9.69e-1775
neural tube1.17e-1652
neural rod1.17e-1652
future spinal cord1.17e-1652
neural keel1.17e-1652
brain5.84e-1547
future brain5.84e-1547
regional part of brain1.45e-1446
ectoderm-derived structure3.38e-1495
ectoderm3.38e-1495
presumptive ectoderm3.38e-1495
gray matter2.71e-1334
anterior neural tube3.05e-1240
adult organism4.39e-1251
brain grey matter6.83e-1229
regional part of telencephalon6.83e-1229
telencephalon6.83e-1229
regional part of forebrain1.12e-1139
forebrain1.12e-1139
future forebrain1.12e-1139
neurectoderm1.50e-1164
neural plate1.50e-1164
presumptive neural plate1.50e-1164
ecto-epithelium1.28e-1073
cerebral cortex8.35e-1021
cerebral hemisphere8.35e-1021
pallium8.35e-1021
regional part of cerebral cortex5.10e-0917
pre-chordal neural plate1.89e-0849
occipital lobe1.07e-0710
visual cortex1.07e-0710
neocortex1.07e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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