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MCL coexpression mm9:1585: Difference between revisions

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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000073!1.21e-13!54;UBERON:0001049!1.31e-12!52;UBERON:0005068!1.31e-12!52;UBERON:0006241!1.31e-12!52;UBERON:0007135!1.31e-12!52;UBERON:0002020!1.57e-12!34;UBERON:0000955!2.99e-10!47;UBERON:0006238!2.99e-10!47;UBERON:0003528!3.22e-10!29;UBERON:0002791!3.22e-10!29;UBERON:0001893!3.22e-10!29;UBERON:0002616!6.99e-10!46;UBERON:0003080!3.89e-09!40;UBERON:0002346!8.25e-09!64;UBERON:0003075!8.25e-09!64;UBERON:0007284!8.25e-09!64;UBERON:0002780!1.35e-08!39;UBERON:0001890!1.35e-08!39;UBERON:0006240!1.35e-08!39;UBERON:0001017!1.74e-08!73;UBERON:0001016!1.14e-07!75;UBERON:0010371!2.06e-07!73;UBERON:0000064!3.35e-07!99;UBERON:0003056!4.29e-07!49
|ontology_enrichment_uberon=UBERON:0000073!1.21e-13!54;UBERON:0001049!1.31e-12!52;UBERON:0005068!1.31e-12!52;UBERON:0006241!1.31e-12!52;UBERON:0007135!1.31e-12!52;UBERON:0002020!1.57e-12!34;UBERON:0000955!2.99e-10!47;UBERON:0006238!2.99e-10!47;UBERON:0003528!3.22e-10!29;UBERON:0002791!3.22e-10!29;UBERON:0001893!3.22e-10!29;UBERON:0002616!6.99e-10!46;UBERON:0003080!3.89e-09!40;UBERON:0002346!8.25e-09!64;UBERON:0003075!8.25e-09!64;UBERON:0007284!8.25e-09!64;UBERON:0002780!1.35e-08!39;UBERON:0001890!1.35e-08!39;UBERON:0006240!1.35e-08!39;UBERON:0001017!1.74e-08!73;UBERON:0001016!1.14e-07!75;UBERON:0010371!2.06e-07!73;UBERON:0000064!3.35e-07!99;UBERON:0003056!4.29e-07!49
|tfbs_overrepresentation_for_novel_motifs=0.557864,1.52338,0.529553,0.603273,0.406364,0.618805,0.715644,0.300268,0.310789,1.22306,0.668936,0.702872,0.812978,0.728641,0.424775,0,0.930881,0.397593,0.283802,0.185796,0.489529,0.44579,0.727684,0.404661,0.537749,0.757752,0.274609,0.641282,0.456327,0.645258,0.626183,1.03545,1.80782,0.253145,1.91085,1.68786,0.384813,0.699032,0.360612,1.57622,0.401916,0.631725,0.419293,0.426986,0.227872,0.591277,0.847828,0.658142,0.115788,0.459555,0.912738,1.84811,0.220111,1.18062,1.19842,0.73621,0.469329,0.689304,0.26467,1.74061,1.01481,0.796017,0.323911,0.901018,0.747985,0.943088,1.33705,1.68977,1.00999,1.54147,1.26875,0.30684,0.152094,1.23259,1.31774,1.27178,0.70455,0.835925,0.997094,0.494135,0.830212,0.948899,0.794502,0.293164,1.1148,1.99513,0.297068,0.227755,0.852952,1.85284,1.40768,1.11989,1.04863,0.412897,0.356133,0.89388,0.806207,1.05152,0.848095,0.20438,0.384901,1.03517,1.16282,0.913356,0.91226,2.58845,0.97421,0.653843,0.499439,1.23125,0.550229,1.16464,0.495367,0.674448,1.41481,0.399936,1.64321,1.47653,0.932233,0.380707,1.23809,0.879184,0.759676,0.834976,1.46955,1.00091,0.724289,1.04166,1.33551,0.416189,1.14546,0.595426,1.3055,0.750642,1.43666,0.143464,0.566955,0.633235,1.3869,2.2222,1.82084,1.34183,0.772375,1.04623,0.905521,0.632211,0.851091,2.18247,0.569503,0.408309,1.21592,1.33841,1.18223,0.908552,0.749664,1.26545,0.787153,0.438007,0.555203,1.39093,1.39653,1.11392,1.00137,0.547782,0.90208,0.741834,0.383572,0.701187,1.14345
}}
}}

Revision as of 20:08, 26 November 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:74537834..74537895,-p1@Pafah1b1
Mm9::chr16:91011274..91011314,-p1@Synj1
Mm9::chr16:93712169..93712182,+p2@Dopey2
Mm9::chr1:37356727..37356782,+p1@Inpp4a
Mm9::chr4:120689806..120689866,-p1@Smap2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042577lipid phosphatase activity0.000375173200338662
GO:0004437inositol or phosphatidylinositol phosphatase activity0.00180936514812023
GO:0006797polyphosphate metabolic process0.00761518654467758
GO:0017120polyphosphoinositide phosphatase activity0.00761518654467758
GO:0006798polyphosphate catabolic process0.00761518654467758
GO:0016316phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity0.0126905868252215
GO:0001675acrosome formation0.0142753457569309
GO:0008090retrograde axon cargo transport0.0142753457569309
GO:0047496vesicle transport along microtubule0.0186535788948009
GO:0004439phosphoinositide 5-phosphatase activity0.0186535788948009
GO:0016791phosphoric monoester hydrolase activity0.0186535788948009
GO:0042578phosphoric ester hydrolase activity0.0272791496909187
GO:0008088axon cargo transport0.0292603068847647



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)6.74e-1023
neuroblast (sensu Vertebrata)6.74e-1023

Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.21e-1354
neural tube1.31e-1252
neural rod1.31e-1252
future spinal cord1.31e-1252
neural keel1.31e-1252
gray matter1.57e-1234
brain2.99e-1047
future brain2.99e-1047
brain grey matter3.22e-1029
regional part of telencephalon3.22e-1029
telencephalon3.22e-1029
regional part of brain6.99e-1046
anterior neural tube3.89e-0940
neurectoderm8.25e-0964
neural plate8.25e-0964
presumptive neural plate8.25e-0964
regional part of forebrain1.35e-0839
forebrain1.35e-0839
future forebrain1.35e-0839
central nervous system1.74e-0873
nervous system1.14e-0775
ecto-epithelium2.06e-0773
organ part3.35e-0799
pre-chordal neural plate4.29e-0749


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}