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MCL coexpression mm9:1331

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:79849983..79850006,+p2@Mpp5
Mm9::chr19:6306626..6306638,+p4@Cdc42bpg
Mm9::chr2:167906524..167906535,+p4@Pard6b
Mm9::chr2:167906603..167906622,+p1@Pard6b
Mm9::chr2:167906639..167906655,+p2@Pard6b
Mm9::chr2:4638871..4638939,+p1@Bend7


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005923tight junction0.00170156244089007
GO:0043296apical junction complex0.00170156244089007
GO:0016327apicolateral plasma membrane0.00170156244089007
GO:0005911intercellular junction0.00355302463365568
GO:0004385guanylate kinase activity0.00933391733597315
GO:0030054cell junction0.0153730212532083
GO:0019201nucleotide kinase activity0.0249864984349492
GO:0016776phosphotransferase activity, phosphate group as acceptor0.0407822118572064
GO:0019205nucleobase, nucleoside, nucleotide kinase activity0.0426733997204883
GO:0016301kinase activity0.0426733997204883
GO:0019992diacylglycerol binding0.0426733997204883
GO:0005938cell cortex0.0426733997204883
GO:0016772transferase activity, transferring phosphorus-containing groups0.0426733997204883
GO:0007242intracellular signaling cascade0.0426733997204883



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
epithelial cell2.06e-0725

Uber Anatomy
Ontology termp-valuen
intestine2.41e-1431
gastrointestinal system3.96e-1247
mucosa3.51e-0915
anatomical space4.86e-0957
endoderm-derived structure5.68e-09118
endoderm5.68e-09118
presumptive endoderm5.68e-09118
thoracic cavity element6.69e-0917
thoracic segment organ6.69e-0917
thoracic cavity6.69e-0917
thoracic segment of trunk6.69e-0917
respiratory primordium6.69e-0917
endoderm of foregut6.69e-0917
immaterial anatomical entity9.10e-0979
digestive system1.29e-08116
digestive tract1.29e-08116
primitive gut1.29e-08116
intestinal mucosa2.69e-0813
anatomical wall2.69e-0813
wall of intestine2.69e-0813
gastrointestinal system mucosa2.69e-0813
trunk region element5.42e-0879
subdivision of digestive tract6.01e-08114
epithelial bud3.95e-0717
lung4.16e-0714
respiratory tube4.16e-0714
respiration organ4.16e-0714
pair of lungs4.16e-0714
lung primordium4.16e-0714
lung bud4.16e-0714


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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