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Coexpression cluster:C337

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Full id: C337_ovary_testis_Adipocyte_mesothelioma_chorionic_placenta_spleen



Phase1 CAGE Peaks

Hg19::chr11:126297301..126297307,+p@chr11:126297301..126297307
+
Hg19::chr11:32449555..32449601,-p@chr11:32449555..32449601
-
Hg19::chr11:77282391..77282402,+p@chr11:77282391..77282402
+
Hg19::chr12:53817633..53817654,+p2@AMHR2
Hg19::chr14:24162052..24162064,+p@chr14:24162052..24162064
+
Hg19::chr14:24162221..24162248,+p@chr14:24162221..24162248
+
Hg19::chr15:95869470..95869478,+p@chr15:95869470..95869478
+
Hg19::chr15:95869480..95869493,+p@chr15:95869480..95869493
+
Hg19::chr17:42154416..42154417,-p12@HDAC5
Hg19::chr17:48912744..48912756,+p6@WFIKKN2
Hg19::chr17:48912862..48912869,+p13@WFIKKN2
Hg19::chr17:48913152..48913158,+p9@WFIKKN2
Hg19::chr19:14223852..14223882,-p7@PRKACA
Hg19::chr19:35800769..35800809,+p@chr19:35800769..35800809
+
Hg19::chr19:35800815..35800836,+p@chr19:35800815..35800836
+
Hg19::chr19:7197281..7197297,+p@chr19:7197281..7197297
+
Hg19::chr1:110993754..110993788,+p1@PROK1
Hg19::chr1:110993795..110993824,+p2@PROK1
Hg19::chr1:111970353..111970358,-p2@OVGP1
Hg19::chr1:205326089..205326108,-p7@KLHDC8A
Hg19::chr1:205326161..205326172,-p12@KLHDC8A
Hg19::chr1:205342383..205342394,+p1@LOC284576
Hg19::chr1:38411522..38411549,-p10@INPP5B
Hg19::chr20:32850613..32850632,+p@chr20:32850613..32850632
+
Hg19::chr2:11696330..11696373,+p23@GREB1
Hg19::chr2:11696464..11696478,+p12@GREB1
Hg19::chr2:11696495..11696507,+p16@GREB1
Hg19::chr2:11696574..11696586,+p17@GREB1
Hg19::chr3:151257198..151257223,-p@chr3:151257198..151257223
-
Hg19::chr3:151257224..151257250,-p@chr3:151257224..151257250
-
Hg19::chr3:15374659..15374696,-p10@SH3BP5
Hg19::chr5:79946291..79946314,-p@chr5:79946291..79946314
-
Hg19::chr6:151314557..151314569,+p@chr6:151314557..151314569
+
Hg19::chr8:38002524..38002528,-p@chr8:38002524..38002528
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0001880Mullerian duct regression0.049487045737182
GO:0060033anatomical structure regression0.049487045737182
GO:0004439phosphoinositide 5-phosphatase activity0.049487045737182
GO:0005071transmembrane receptor protein serine/threonine kinase signaling protein activity0.049487045737182
GO:0004445inositol-polyphosphate 5-phosphatase activity0.049487045737182
GO:0046030inositol trisphosphate phosphatase activity0.049487045737182
GO:0004691cAMP-dependent protein kinase activity0.049487045737182
GO:0045843negative regulation of striated muscle development0.049487045737182
GO:0022414reproductive process0.049487045737182
GO:0004690cyclic nucleotide-dependent protein kinase activity0.049487045737182
GO:0042577lipid phosphatase activity0.049487045737182
GO:0016202regulation of striated muscle development0.049487045737182
GO:0016566specific transcriptional repressor activity0.049487045737182
GO:0006032chitin catabolic process0.049487045737182
GO:0006046N-acetylglucosamine catabolic process0.049487045737182
GO:0006043glucosamine catabolic process0.049487045737182
GO:0046348amino sugar catabolic process0.049487045737182
GO:0006030chitin metabolic process0.049487045737182
GO:0004568chitinase activity0.049487045737182



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism1.47e-27115
central nervous system2.91e-1482
regional part of nervous system1.48e-1394
nervous system1.48e-1394
neural tube2.56e-1357
neural rod2.56e-1357
future spinal cord2.56e-1357
neural keel2.56e-1357
brain5.92e-1269
future brain5.92e-1269
regional part of brain6.99e-1259
neurectoderm6.49e-1190
neural plate1.53e-1086
presumptive neural plate1.53e-1086
anterior neural tube1.17e-0942
regional part of forebrain1.71e-0941
forebrain1.71e-0941
future forebrain1.71e-0941
pre-chordal neural plate3.26e-0761


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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