MCL coexpression mm9:672

Phase1 CAGE Peaks

	Short description
Mm9::chr14:25309931..25309947,+	p1@LOC677113 p1@Rps24
Mm9::chr14:76245128..76245154,+	p1@Tpt1
Mm9::chr17:24857047..24857063,+	p1@Gm10420 p1@Gm5786 p1@Gm8842 p1@Rps2
Mm9::chr19:18001042..18001045,+	p@chr19:18001042..18001045 +
Mm9::chr19:51866690..51866693,+	p@chr19:51866690..51866693 +
Mm9::chr19:8955322..8955344,-	p2@AI462493
Mm9::chr1:88806278..88806282,-	p1@ENSMUST00000167233
Mm9::chr5:108329551..108329596,+	p1@Gm14217 p1@Rpl5
Mm9::chr9:19732764..19732768,-	p1@ENSMUST00000165126
Mm9::chr9:64021171..64021195,+	p1@Rpl4
Mm9::chrX:86204522..86204523,+	p1@ENSMUST00000121800

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0008665	2'-phosphotransferase activity	0.00640920285549399
GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	0.00640920285549399
GO:0006388	tRNA splicing	0.00640920285549399

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
hematopoietic cell	1.53e-10	32
hematopoietic oligopotent progenitor cell	1.53e-10	32
hematopoietic stem cell	1.53e-10	32
angioblastic mesenchymal cell	1.53e-10	32
hematopoietic multipotent progenitor cell	1.53e-10	32
lymphocyte	4.10e-09	13
common lymphoid progenitor	4.10e-09	13
lymphoid lineage restricted progenitor cell	6.58e-09	12
T cell	2.72e-08	11
pro-T cell	2.72e-08	11
connective tissue cell	1.33e-07	46
mesenchymal cell	1.33e-07	46
mature alpha-beta T cell	2.89e-07	9
alpha-beta T cell	2.89e-07	9
immature T cell	2.89e-07	9
mature T cell	2.89e-07	9
immature alpha-beta T cell	2.89e-07	9
hematopoietic lineage restricted progenitor cell	4.27e-07	25
leukocyte	5.18e-07	17
nongranular leukocyte	5.18e-07	17

Uber Anatomy

Ontology term	p-value	n
connective tissue	1.33e-07	46

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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