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MCL coexpression mm9:945

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:24467811..24467828,-p1@ENSMUST00000147704
Mm9::chr13:24467831..24467841,-p3@ENSMUST00000147704
Mm9::chr13:24467891..24467902,-p2@ENSMUST00000147704
Mm9::chr13:24467903..24467914,+p10@Cmah
Mm9::chr5:36896690..36896700,-p@chr5:36896690..36896700
-
Mm9::chr6:39329973..39329994,+p@chr6:39329973..39329994
+
Mm9::chr7:17429487..17429492,+p@chr7:17429487..17429492
+
Mm9::chr8:124999903..124999926,-p2@Rnf166


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030338CMP-N-acetylneuraminate monooxygenase activity0.00416358505650466
GO:0016716oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen0.00416358505650466
GO:0046381CMP-N-acetylneuraminate metabolic process0.00416358505650466
GO:0006054N-acetylneuraminate metabolic process0.00780608038529814
GO:0009225nucleotide-sugar metabolic process0.00858527691340211
GO:0016681oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor0.00858527691340211
GO:0016679oxidoreductase activity, acting on diphenols and related substances as donors0.00858527691340211
GO:0008121ubiquinol-cytochrome-c reductase activity0.00858527691340211
GO:00515372 iron, 2 sulfur cluster binding0.00971183807795139
GO:0006040amino sugar metabolic process0.0149798725366914
GO:0051536iron-sulfur cluster binding0.0223541333869878
GO:0051540metal cluster binding0.0223541333869878
GO:0015078hydrogen ion transmembrane transporter activity0.0427151651692191
GO:0015077monovalent inorganic cation transmembrane transporter activity0.0427151651692191
GO:0004497monooxygenase activity0.0479560692337963
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen0.0479560692337963
GO:0022890inorganic cation transmembrane transporter activity0.0479560692337963
GO:0046914transition metal ion binding0.0492165645382467



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
thymus2.05e-2023
neck2.05e-2023
respiratory system epithelium2.05e-2023
hemolymphoid system gland2.05e-2023
pharyngeal epithelium2.05e-2023
thymic region2.05e-2023
pharyngeal gland2.05e-2023
entire pharyngeal arch endoderm2.05e-2023
thymus primordium2.05e-2023
early pharyngeal endoderm2.05e-2023
pharynx2.09e-1924
gland of gut2.09e-1924
upper respiratory tract2.09e-1924
chordate pharynx2.09e-1924
pharyngeal arch system2.09e-1924
pharyngeal region of foregut2.09e-1924
hemopoietic organ1.47e-1729
immune organ1.47e-1729
segment of respiratory tract7.84e-1727
hemolymphoid system7.31e-1548
immune system7.31e-1548
hematopoietic system2.03e-1445
blood island2.03e-1445
respiratory tract2.13e-1441
respiratory system5.99e-1442
mixed endoderm/mesoderm-derived structure7.22e-1435
organ segment3.86e-1235
craniocervical region1.06e-1136
anterior region of body3.26e-0943
lateral plate mesoderm1.90e-0887
unilaminar epithelium9.64e-0866
mesoderm5.37e-07120
mesoderm-derived structure5.37e-07120
presumptive mesoderm5.37e-07120
endo-epithelium7.94e-0769

Disease
Ontology termp-valuen
musculoskeletal system cancer1.92e-083
muscle cancer1.92e-083


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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