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MCL coexpression mm9:2844

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:44829403..44829438,+p11@Jarid2
Mm9::chr6:122290543..122290561,-p6@Phc1
Mm9::chr7:31933955..31933966,-p@chr7:31933955..31933966
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0048536spleen development0.0306150352991968
GO:0048538thymus development0.0306150352991968
GO:0001739sex chromatin0.0306150352991968
GO:0000803sex chromosome0.0306150352991968
GO:0001889liver development0.0361001463040186
GO:0005720nuclear heterochromatin0.0361001463040186
GO:0000790nuclear chromatin0.0397461311794092
GO:0000792heterochromatin0.0397461311794092
GO:0016604nuclear body0.0397461311794092



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br><br><br>


Cell Type
Ontology termp-valuen
lymphocyte1.09e-1213
common lymphoid progenitor1.09e-1213
lymphoid lineage restricted progenitor cell1.42e-1212
T cell1.32e-1111
pro-T cell1.32e-1111
mature alpha-beta T cell1.29e-109
alpha-beta T cell1.29e-109
immature T cell1.29e-109
mature T cell1.29e-109
immature alpha-beta T cell1.29e-109
CD4-positive, alpha-beta T cell1.40e-098
nucleate cell2.04e-0916
leukocyte1.35e-0817
nongranular leukocyte1.35e-0817
thymocyte1.58e-076
double negative thymocyte1.58e-076
naive T cell1.58e-076
double-positive, alpha-beta thymocyte1.58e-076
CD4-positive, alpha-beta thymocyte1.58e-076
naive thymus-derived CD4-positive, alpha-beta T cell1.58e-076
DN4 thymocyte1.58e-076
DN1 thymic pro-T cell1.58e-076
DN2 thymocyte1.58e-076
DN3 thymocyte1.58e-076
immature single positive thymocyte1.58e-076
early T lineage precursor1.58e-076
mature CD4 single-positive thymocyte1.58e-076
resting double-positive thymocyte1.58e-076
double-positive blast1.58e-076
CD69-positive double-positive thymocyte1.58e-076
CD69-positive, CD4-positive single-positive thymocyte1.58e-076
CD4-positive, CD8-intermediate double-positive thymocyte1.58e-076
CD24-positive, CD4 single-positive thymocyte1.58e-076
hematopoietic cell5.68e-0732
hematopoietic oligopotent progenitor cell5.68e-0732
hematopoietic stem cell5.68e-0732
angioblastic mesenchymal cell5.68e-0732
hematopoietic multipotent progenitor cell5.68e-0732


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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