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Coexpression cluster:C390

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Full id: C390_Neurons_Synoviocyte_optic_Neural_heart_umbilical_CD14



Phase1 CAGE Peaks

Hg19::chr10:39093494..39093511,+p@chr10:39093494..39093511
+
Hg19::chr10:39099123..39099125,+p@chr10:39099123..39099125
+
Hg19::chr10:42379883..42379894,+p@chr10:42379883..42379894
+
Hg19::chr10:63305248..63305260,-p@chr10:63305248..63305260
-
Hg19::chr14:28994139..28994143,-p@chr14:28994139..28994143
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Hg19::chr14:88322493..88322499,-p@chr14:88322493..88322499
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Hg19::chr15:53409038..53409040,+p@chr15:53409038..53409040
+
Hg19::chr17:37760927..37760931,+p@chr17:37760927..37760931
+
Hg19::chr1:142537706..142537723,-p@chr1:142537706..142537723
-
Hg19::chr1:142537912..142537938,-p@chr1:142537912..142537938
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Hg19::chr1:142539672..142539687,-p@chr1:142539672..142539687
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Hg19::chr1:163429080..163429090,-p@chr1:163429080..163429090
-
Hg19::chr1:73856139..73856141,+p@chr1:73856139..73856141
+
Hg19::chr21:11124114..11124128,+p@chr21:11124114..11124128
+
Hg19::chr22:42393701..42393712,-p@chr22:42393701..42393712
-
Hg19::chr2:133029373..133029386,-p@chr2:133029373..133029386
-
Hg19::chr4:58205081..58205083,+p@chr4:58205081..58205083
+
Hg19::chr4:7865693..7865721,+p@chr4:7865693..7865721
+
Hg19::chr9:108995325..108995329,+p@chr9:108995325..108995329
+
Hg19::chr9:44070694..44070727,+p@chr9:44070694..44070727
+
Hg19::chr9:44070749..44070754,+p@chr9:44070749..44070754
+
Hg19::chrY:13450855..13450866,+p@chrY:13450855..13450866
+
Hg19::chrY:13650836..13650854,-p@chrY:13650836..13650854
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Hg19::chrY:28817276..28817283,-p@chrY:28817276..28817283
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Hg19::chrY:58856051..58856076,+p@chrY:58856051..58856076
+
Hg19::chrY:58884631..58884640,+p@chrY:58884631..58884640
+
Hg19::chrY:58903885..58903887,+p@chrY:58903885..58903887
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuronal stem cell1.15e-448
neuron3.27e-226
neuroblast3.27e-226
electrically signaling cell3.27e-226
synovial cell3.66e-203
neural cell2.61e-1325
hepatic stem cell2.67e-082
hepatic mesenchymal stem cell2.67e-082
GAG secreting cell2.44e-079
carbohydrate secreting cell2.44e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.20221e-08
MA0004.10.115462
MA0006.10.043712
MA0007.10.105458
MA0009.10.45361
MA0014.10.00010589
MA0017.10.463835
MA0019.10.206961
MA0024.10.366071
MA0025.10.570597
MA0027.12.00534
MA0028.10.0494049
MA0029.10.381857
MA0030.10.372472
MA0031.10.320773
MA0038.10.524126
MA0040.10.38667
MA0041.15.70123
MA0042.14.53195
MA0043.10.453881
MA0046.10.444311
MA0048.10.00182717
MA0050.10.108721
MA0051.10.517477
MA0052.11.01149
MA0055.10.000405343
MA0056.10
MA0057.10.0369704
MA0058.10.0687016
MA0059.10.0681464
MA0060.10.0133608
MA0061.10.0465062
MA0063.10
MA0066.10.177154
MA0067.10.739032
MA0068.10.0831041
MA0069.10.441028
MA0070.10.431528
MA0071.10.152483
MA0072.10.427724
MA0073.10.000176401
MA0074.10.516295
MA0076.10.0757217
MA0077.10.421218
MA0078.10.242013
MA0081.13.05941
MA0083.10.460049
MA0084.10.916043
MA0087.10.425657
MA0088.10.0317537
MA0089.10
MA0090.11.4777
MA0091.10.116893
MA0092.10.0969694
MA0093.10.0447606
MA0095.10
MA0098.10
MA0100.10.546121
MA0101.10.0459133
MA0103.10.157938
MA0105.10.00795696
MA0106.10.204305
MA0107.10.023874
MA0108.20.318371
MA0109.10
MA0111.10.298621
MA0113.10.2156
MA0114.10.24238
MA0115.11.60402
MA0116.10.0247359
MA0117.10.486035
MA0119.10.0614144
MA0122.11.26786
MA0124.10.630319
MA0125.10.554615
MA0130.10
MA0131.10.255226
MA0132.10
MA0133.10
MA0135.11.20615
MA0136.10.535282
MA0139.10.00756546
MA0140.10.150858
MA0141.10.0674008
MA0142.10.296096
MA0143.10.215723
MA0144.10.0193859
MA0145.10.00365502
MA0146.17.32986e-06
MA0147.10.0256229
MA0148.10.129389
MA0149.16.9991
MA0062.20.00844267
MA0035.20.150428
MA0039.22.09375e-06
MA0138.20.242899
MA0002.20.151075
MA0137.20.051801
MA0104.20.0132287
MA0047.20.196083
MA0112.20.000372926
MA0065.20.176284
MA0150.10.0796342
MA0151.10
MA0152.10.47
MA0153.10.539635
MA0154.10.00106049
MA0155.10.00250158
MA0156.10.195153
MA0157.10.275302
MA0158.10
MA0159.10.025786
MA0160.10.138224
MA0161.10
MA0162.16.41568e-06
MA0163.11.92853e-05
MA0164.10.224291
MA0080.20.687581
MA0018.20.205249
MA0099.20.155103
MA0079.24.16944e-07
MA0102.20.951693
MA0258.10.0789495
MA0259.10.0278251
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.