MCL coexpression mm9:568
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr12:111326146..111326190,- | p@chr12:111326146..111326190 - |
| Mm9::chr13:54891345..54891350,+ | p@chr13:54891345..54891350 + |
| Mm9::chr15:43002727..43002745,- | p5@Rspo2 |
| Mm9::chr16:25865862..25865871,+ | p8@Trp63 |
| Mm9::chr16:25865901..25865908,+ | p@chr16:25865901..25865908 + |
| Mm9::chr18:52718847..52718852,+ | p@chr18:52718847..52718852 + |
| Mm9::chr2:24192402..24192413,+ | p6@Il1rn |
| Mm9::chr2:24192424..24192445,+ | p3@Il1rn |
| Mm9::chr2:24192453..24192465,+ | p5@Il1rn |
| Mm9::chr2:46298201..46298233,- | p1@ENSMUST00000123911 |
| Mm9::chr3:83578591..83578595,- | p@chr3:83578591..83578595 - |
| Mm9::chr6:117124183..117124190,+ | p@chr6:117124183..117124190 + |
| Mm9::chr8:113861783..113861814,- | p2@Mlkl |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0060157 | urinary bladder development | 0.0227907741193229 |
| GO:0007499 | ectoderm and mesoderm interaction | 0.0227907741193229 |
| GO:0030353 | fibroblast growth factor receptor antagonist activity | 0.0256227681126851 |
| GO:0005152 | interleukin-1 receptor antagonist activity | 0.0256227681126851 |
| GO:0048745 | smooth muscle development | 0.0256227681126851 |
| GO:0048019 | receptor antagonist activity | 0.0256227681126851 |
| GO:0030547 | receptor inhibitor activity | 0.0256227681126851 |
| GO:0030859 | polarized epithelial cell differentiation | 0.0256227681126851 |
| GO:0001736 | establishment of planar polarity | 0.0256227681126851 |
| GO:0007164 | establishment of tissue polarity | 0.0256227681126851 |
| GO:0002347 | response to tumor cell | 0.0256227681126851 |
| GO:0030545 | receptor regulator activity | 0.0256227681126851 |
| GO:0007267 | cell-cell signaling | 0.0256227681126851 |
| GO:0010464 | regulation of mesenchymal cell proliferation | 0.0256227681126851 |
| GO:0002053 | positive regulation of mesenchymal cell proliferation | 0.0256227681126851 |
| GO:0010463 | mesenchymal cell proliferation | 0.0256227681126851 |
| GO:0001738 | morphogenesis of a polarized epithelium | 0.0294697120049581 |
| GO:0005149 | interleukin-1 receptor binding | 0.0303602380595734 |
| GO:0030308 | negative regulation of cell growth | 0.031156630686983 |
| GO:0031069 | hair follicle morphogenesis | 0.0318730099422934 |
| GO:0045792 | negative regulation of cell size | 0.039307685169038 |
| GO:0005104 | fibroblast growth factor receptor binding | 0.039307685169038 |
| GO:0030216 | keratinocyte differentiation | 0.0436033990801299 |
| GO:0030073 | insulin secretion | 0.0436033990801299 |
| GO:0045926 | negative regulation of growth | 0.0440452218976995 |
| GO:0004672 | protein kinase activity | 0.0440452218976995 |
| GO:0006468 | protein amino acid phosphorylation | 0.0454767631410165 |
| GO:0030072 | peptide hormone secretion | 0.0454767631410165 |
| GO:0002790 | peptide secretion | 0.0454767631410165 |
| GO:0016773 | phosphotransferase activity, alcohol group as acceptor | 0.0465059855234204 |
| GO:0016310 | phosphorylation | 0.0465059855234204 |
| GO:0042475 | odontogenesis of dentine-containing teeth | 0.0465059855234204 |
| GO:0030855 | epithelial cell differentiation | 0.0465059855234204 |
| GO:0042476 | odontogenesis | 0.0465059855234204 |
| GO:0015833 | peptide transport | 0.0465059855234204 |
| GO:0022404 | molting cycle process | 0.0465059855234204 |
| GO:0001942 | hair follicle development | 0.0465059855234204 |
| GO:0022405 | hair cycle process | 0.0465059855234204 |
| GO:0007166 | cell surface receptor linked signal transduction | 0.0465059855234204 |
| GO:0046879 | hormone secretion | 0.0465059855234204 |
| GO:0042633 | hair cycle | 0.0465059855234204 |
| GO:0042303 | molting cycle | 0.0465059855234204 |
| GO:0006793 | phosphorus metabolic process | 0.0482960797623162 |
| GO:0006796 | phosphate metabolic process | 0.0482960797623162 |
| GO:0007498 | mesoderm development | 0.0482960797623162 |
| GO:0048730 | epidermis morphogenesis | 0.0482960797623162 |
| GO:0007219 | Notch signaling pathway | 0.0482960797623162 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| smooth muscle cell | 8.11e-12 | 3 |
| vascular associated smooth muscle cell | 8.11e-12 | 3 |
| aortic smooth muscle cell | 8.11e-12 | 3 |
| smooth muscle myoblast | 8.11e-12 | 3 |
| Ontology term | p-value | n |
|---|---|---|
| smooth muscle tissue | 8.11e-12 | 3 |
| blood vessel smooth muscle | 8.11e-12 | 3 |
| arterial system smooth muscle | 8.11e-12 | 3 |
| artery smooth muscle tissue | 8.11e-12 | 3 |
| aorta smooth muscle tissue | 8.11e-12 | 3 |
| zone of skin | 1.38e-11 | 5 |
| skin epidermis | 1.38e-11 | 5 |
| skin of body | 1.38e-11 | 5 |
| integument | 1.38e-11 | 5 |
| surface | 1.38e-11 | 5 |
| outer epithelium | 1.38e-11 | 5 |
| integumental system | 1.38e-11 | 5 |
| enveloping layer of ectoderm | 1.38e-11 | 5 |
| aorta | 5.64e-09 | 4 |
| artery | 5.64e-09 | 4 |
| systemic artery | 5.64e-09 | 4 |
| arterial blood vessel | 5.64e-09 | 4 |
| systemic arterial system | 5.64e-09 | 4 |
| aortic system | 5.64e-09 | 4 |
| arterial system | 5.64e-09 | 4 |
| vessel | 2.92e-07 | 5 |
| epithelial tube open at both ends | 2.92e-07 | 5 |
| blood vessel | 2.92e-07 | 5 |
| vasculature | 2.92e-07 | 5 |
| vascular system | 2.92e-07 | 5 |
| blood vasculature | 2.92e-07 | 5 |
| vascular cord | 2.92e-07 | 5 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.00104704 |
| MA0004.1 | 0.279808 |
| MA0006.1 | 0.14766 |
| MA0007.1 | 0.267314 |
| MA0009.1 | 0.678286 |
| MA0014.1 | 0.0830612 |
| MA0017.1 | 0.166909 |
| MA0019.1 | 0.506787 |
| MA0024.1 | 0.636635 |
| MA0025.1 | 0.9035 |
| MA0027.1 | 2.3071 |
| MA0028.1 | 0.470606 |
| MA0029.1 | 0.616052 |
| MA0030.1 | 0.622264 |
| MA0031.1 | 1.43735 |
| MA0038.1 | 0.405578 |
| MA0040.1 | 0.690239 |
| MA0041.1 | 0.218039 |
| MA0042.1 | 0.207696 |
| MA0043.1 | 0.771094 |
| MA0046.1 | 0.712646 |
| MA0048.1 | 0.0358824 |
| MA0050.1 | 0.840337 |
| MA0051.1 | 1.06334 |
| MA0052.1 | 0.697946 |
| MA0055.1 | 0.0835619 |
| MA0056.1 | 0 |
| MA0057.1 | 0.302463 |
| MA0058.1 | 0.202403 |
| MA0059.1 | 0.212009 |
| MA0060.1 | 0.0941959 |
| MA0061.1 | 1.20639 |
| MA0063.1 | 0 |
| MA0066.1 | 0.395746 |
| MA0067.1 | 1.01206 |
| MA0068.1 | 0.571204 |
| MA0069.1 | 0.698271 |
| MA0070.1 | 0.688999 |
| MA0071.1 | 0.838726 |
| MA0072.1 | 0.680902 |
| MA0073.1 | 0.000800861 |
| MA0074.1 | 0.363923 |
| MA0076.1 | 0.181159 |
| MA0077.1 | 0.660245 |
| MA0078.1 | 0.443468 |
| MA0081.1 | 0.230351 |
| MA0083.1 | 1.8156 |
| MA0084.1 | 1.33532 |
| MA0087.1 | 0.728855 |
| MA0088.1 | 0.204026 |
| MA0089.1 | 0 |
| MA0090.1 | 0.251458 |
| MA0091.1 | 0.290854 |
| MA0092.1 | 0.70143 |
| MA0093.1 | 0.161141 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.353762 |
| MA0101.1 | 0.219061 |
| MA0103.1 | 0.174916 |
| MA0105.1 | 0.196316 |
| MA0106.1 | 1.14333 |
| MA0107.1 | 0.508149 |
| MA0108.2 | 2.25321 |
| MA0109.1 | 0 |
| MA0111.1 | 0.263095 |
| MA0113.1 | 0.424958 |
| MA0114.1 | 0.359761 |
| MA0115.1 | 0.773793 |
| MA0116.1 | 0.147513 |
| MA0117.1 | 0.742722 |
| MA0119.1 | 0.219527 |
| MA0122.1 | 0.761823 |
| MA0124.1 | 0.959967 |
| MA0125.1 | 0.887718 |
| MA0130.1 | 0 |
| MA0131.1 | 0.502588 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 0.806261 |
| MA0136.1 | 0.38151 |
| MA0139.1 | 0.942843 |
| MA0140.1 | 0.353662 |
| MA0141.1 | 0.555407 |
| MA0142.1 | 1.40862 |
| MA0143.1 | 2.91753 |
| MA0144.1 | 0.365041 |
| MA0145.1 | 0.4279 |
| MA0146.1 | 0.11048 |
| MA0147.1 | 0.121834 |
| MA0148.1 | 0.293462 |
| MA0149.1 | 0.223436 |
| MA0062.2 | 0.0556611 |
| MA0035.2 | 0.357786 |
| MA0039.2 | 0.120228 |
| MA0138.2 | 0.495254 |
| MA0002.2 | 0.266731 |
| MA0137.2 | 0.55008 |
| MA0104.2 | 0.0856657 |
| MA0047.2 | 0.404891 |
| MA0112.2 | 1.02934 |
| MA0065.2 | 0.429377 |
| MA0150.1 | 0.737147 |
| MA0151.1 | 0 |
| MA0152.1 | 0.404987 |
| MA0153.1 | 0.822355 |
| MA0154.1 | 0.139881 |
| MA0155.1 | 0.105935 |
| MA0156.1 | 0.180505 |
| MA0157.1 | 2.3091 |
| MA0158.1 | 0 |
| MA0159.1 | 0.403827 |
| MA0160.1 | 0.80274 |
| MA0161.1 | 0 |
| MA0162.1 | 0.0186388 |
| MA0163.1 | 0.0025245 |
| MA0164.1 | 0.993886 |
| MA0080.2 | 0.170995 |
| MA0018.2 | 0.390455 |
| MA0099.2 | 2.12597 |
| MA0079.2 | 0.00289425 |
| MA0102.2 | 1.38728 |
| MA0258.1 | 0.336791 |
| MA0259.1 | 0.114734 |
| MA0442.1 | 0 |
