MCL coexpression mm9:2824
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr13:19711627..19711680,- | p1@Epdr1 |
| Mm9::chr2:131735667..131735684,+ | p1@Prnp |
| Mm9::chr2:131735687..131735715,+ | p1@Prnd |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0006878 | cellular copper ion homeostasis | 2.00936887370317e-05 |
| GO:0055070 | copper ion homeostasis | 2.00936887370317e-05 |
| GO:0051260 | protein homooligomerization | 7.81078619014968e-05 |
| GO:0051259 | protein oligomerization | 0.000121306222455019 |
| GO:0005507 | copper ion binding | 0.00031896435691302 |
| GO:0030005 | cellular di-, tri-valent inorganic cation homeostasis | 0.000700884515879918 |
| GO:0055066 | di-, tri-valent inorganic cation homeostasis | 0.000700884515879918 |
| GO:0030003 | cellular cation homeostasis | 0.000700884515879918 |
| GO:0055080 | cation homeostasis | 0.000700884515879918 |
| GO:0048503 | GPI anchor binding | 0.000767524049384828 |
| GO:0006461 | protein complex assembly | 0.000783161993426455 |
| GO:0055082 | cellular chemical homeostasis | 0.000904389109868064 |
| GO:0006873 | cellular ion homeostasis | 0.000904389109868064 |
| GO:0035091 | phosphoinositide binding | 0.00101335011568568 |
| GO:0050801 | ion homeostasis | 0.00101335011568568 |
| GO:0005543 | phospholipid binding | 0.0013638582240156 |
| GO:0048878 | chemical homeostasis | 0.0013638582240156 |
| GO:0019725 | cellular homeostasis | 0.0013638582240156 |
| GO:0065003 | macromolecular complex assembly | 0.00287316699102723 |
| GO:0042592 | homeostatic process | 0.00288700379716113 |
| GO:0008289 | lipid binding | 0.00331646094962967 |
| GO:0022607 | cellular component assembly | 0.00343658938090558 |
| GO:0065008 | regulation of biological quality | 0.00881725972057049 |
| GO:0043169 | cation binding | 0.0133554956062523 |
| GO:0045121 | lipid raft | 0.0138335019063751 |
| GO:0046872 | metal ion binding | 0.0157706284997856 |
| GO:0043167 | ion binding | 0.0161504046373676 |
| GO:0006979 | response to oxidative stress | 0.0163375068120297 |
| GO:0007160 | cell-matrix adhesion | 0.0220620126922838 |
| GO:0031589 | cell-substrate adhesion | 0.0226757069710698 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| non-terminally differentiated cell | 3.88e-13 | 49 |
| ectodermal cell | 3.90e-11 | 44 |
| neurectodermal cell | 3.90e-11 | 44 |
| neural cell | 8.13e-11 | 43 |
| electrically responsive cell | 1.85e-08 | 39 |
| electrically active cell | 1.85e-08 | 39 |
| Ontology term | p-value | n |
|---|---|---|
| ectoderm-derived structure | 5.26e-25 | 95 |
| ectoderm | 5.26e-25 | 95 |
| presumptive ectoderm | 5.26e-25 | 95 |
| nervous system | 4.58e-24 | 75 |
| central nervous system | 2.00e-23 | 73 |
| structure with developmental contribution from neural crest | 4.92e-19 | 92 |
| ecto-epithelium | 4.25e-17 | 73 |
| regional part of nervous system | 9.67e-17 | 54 |
| neural tube | 1.10e-15 | 52 |
| neural rod | 1.10e-15 | 52 |
| future spinal cord | 1.10e-15 | 52 |
| neural keel | 1.10e-15 | 52 |
| neurectoderm | 2.03e-15 | 64 |
| neural plate | 2.03e-15 | 64 |
| presumptive neural plate | 2.03e-15 | 64 |
| brain | 3.31e-15 | 47 |
| future brain | 3.31e-15 | 47 |
| regional part of brain | 1.20e-14 | 46 |
| anatomical conduit | 6.65e-12 | 122 |
| anterior neural tube | 1.72e-11 | 40 |
| tube | 5.74e-11 | 114 |
| regional part of forebrain | 6.92e-11 | 39 |
| forebrain | 6.92e-11 | 39 |
| future forebrain | 6.92e-11 | 39 |
| gray matter | 1.45e-10 | 34 |
| pre-chordal neural plate | 1.66e-10 | 49 |
| brain grey matter | 2.67e-10 | 29 |
| regional part of telencephalon | 2.67e-10 | 29 |
| telencephalon | 2.67e-10 | 29 |
| cerebral cortex | 1.37e-07 | 21 |
| cerebral hemisphere | 1.37e-07 | 21 |
| pallium | 1.37e-07 | 21 |
| regional part of cerebral cortex | 2.53e-07 | 17 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.0699972 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 0.133574 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 3.33329 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 1.97065 |
| MA0051.1 | 2.23119 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 0.190475 |
| MA0056.1 | 0 |
| MA0057.1 | 0.337566 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 1.25521 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 2.46203 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 6.00139 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 0.766354 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 1.80015 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 0.405648 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 0.462282 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 0.541532 |
| MA0145.1 | 2.21145 |
| MA0146.1 | 1.44443 |
| MA0147.1 | 0.556853 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 0.722227 |
| MA0062.2 | 0.412742 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 2.6396 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.29236 |
| MA0065.2 | 0.292912 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 0.840842 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 0.964824 |
| MA0163.1 | 0.477233 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 3.48353 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
