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UBERON:0000981

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Name:femur
Definition:"The femur, or thigh bone, is the most proximal (closest to the body) bone of the leg in vertebrates capable of walking or jumping, such as most land mammals, birds, many reptiles such as lizards, and amphibians such as frogs. In vertebrates with four legs, the femur is found only in the rear legs. Some species of whales[1], snakes[2], and other non-walking vertebrates have vestigial femurs. One of the earliest known vertebrates to have a femur is the Eusthenopteron, a prehistoric lobe-finned fish from the Late Devonian period." [Wikipedia:Femur]
Xrefs:
links:

AAO:0000889
BTO:0001284
EFO:0001396
EMAPA:18514
EMAPA:19143
FMA:9611
GAID:199
galen:Femur
[ 200px-Gray252.png 200px-Gray252.png]
MA:0001359
MESH:A.02.835.232.500.247
ncithesaurus:Femur
OpenCyc:Mx4rvVjOJJwpEbGdrcN5Y29ycA
SCTID:182046008
VHOG:0001159

XAO:0003214
Synonyms: "femoral bone" RELATED [BTO:0001284]
"os femorale" RELATED [BTO:0001284]
"os femoris" RELATED [BTO:0001284]
"thigh bone" EXACT []
Comments:homologous to proximal metapterygial mesomere [Hall 2007]
Alt_id: UBERON:FBbt_00004644-FMA_9611-MA_0001359
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002495(long bone),UBERON:0003608(hindlimb long bone),UBERON:0003826(upper leg bone),UBERON:0008202(bone of hip region)
develops_from:UBERON:0010129(femur cartilage element)
part_of:UBERON:0000376(hindlimb stylopod)



Children

derives from:FF:0011462 (mouse bone- os femoris - neonate N16 sample),FF:0011463 (mouse bone- os femoris - neonate N2 sample),FF:0011464 (mouse bone- os femoris - adult sample),FF:0011467 (mouse bone- os femoris - neonate N20 sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000981 (femur), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
3.4e-49FFCP PHASE2:Mm9::chr11:77624716..77624729,+#_6ac31d6946c421accfd0562306034bc3p26@Myo18a
3.4e-49FFCP PHASE1:Mm9::chr11:77624716..77624729,+#_6ac31d6946c421accfd0562306034bc3p26@Myo18a
4.96e-49FFCP PHASE2:Mm9::chr8:75097542..75097549,+#_9375c8bd7d58833c1a99da7c9fdee12cp@chr8:75097542..75097549, +
4.96e-49FFCP PHASE1:Mm9::chr9:21934585..21934591,-#_9375c8bd7d58833c1a99da7c9fdee12cp@chr9:21934585..21934591, -
4.96e-49FFCP PHASE2:Mm9::chr2:32482372..32482381,+#_9375c8bd7d58833c1a99da7c9fdee12cp@chr2:32482372..32482381, +
4.96e-49FFCP PHASE2:Mm9::chr9:21934585..21934591,-#_9375c8bd7d58833c1a99da7c9fdee12cp@chr9:21934585..21934591, -
4.96e-49FFCP PHASE1:Mm9::chr8:75097542..75097549,+#_9375c8bd7d58833c1a99da7c9fdee12cp@chr8:75097542..75097549, +
4.96e-49FFCP PHASE1:Mm9::chr2:32482372..32482381,+#_9375c8bd7d58833c1a99da7c9fdee12cp@chr2:32482372..32482381, +
3.15e-44FFCP PHASE2:Mm9::chr6:51525810..51525817,+#_6d7809c25378bb295701ea4d2b23cb3cp@chr6:51525810..51525817, +
3.15e-44FFCP PHASE1:Mm9::chr6:51525810..51525817,+#_6d7809c25378bb295701ea4d2b23cb3cp@chr6:51525810..51525817, +
9.78e-40FFCP PHASE1:Mm9::chr19:4876870..4876880,-#_6fcbc1695446e20e36b01318d4261d1ep@chr19:4876870..4876880, -
9.78e-40FFCP PHASE2:Mm9::chr19:4876870..4876880,-#_6fcbc1695446e20e36b01318d4261d1ep@chr19:4876870..4876880, -
1.15e-39FFCP PHASE1:Mm9::chr1:174140324..174140335,-#_a5d807d8733e2f8badc6454b621077ecp@chr1:174140324..174140335, -
1.15e-39FFCP PHASE2:Mm9::chr11:67063327..67063335,+#_a5d807d8733e2f8badc6454b621077ecp@chr11:67063327..67063335, +
1.15e-39FFCP PHASE1:Mm9::chr16:24096441..24096449,+#_a5d807d8733e2f8badc6454b621077ecp@chr16:24096441..24096449, +
1.15e-39FFCP PHASE1:Mm9::chr6:4490674..4490679,+#_a5d807d8733e2f8badc6454b621077ecp@chr6:4490674..4490679, +
1.15e-39FFCP PHASE2:Mm9::chr6:4490674..4490679,+#_a5d807d8733e2f8badc6454b621077ecp@chr6:4490674..4490679, +
1.15e-39FFCP PHASE1:Mm9::chr11:67063327..67063335,+#_a5d807d8733e2f8badc6454b621077ecp@chr11:67063327..67063335, +
1.15e-39FFCP PHASE2:Mm9::chr16:24096441..24096449,+#_a5d807d8733e2f8badc6454b621077ecp@chr16:24096441..24096449, +
1.15e-39FFCP PHASE2:Mm9::chr1:174140324..174140335,-#_a5d807d8733e2f8badc6454b621077ecp@chr1:174140324..174140335, -
1.55e-39FFCP PHASE2:Mm9::chr1:174143249..174143260,-#_82ce2ac21a3ed20589eae8aee1e9078ep@chr1:174143249..174143260, -
1.55e-39FFCP PHASE1:Mm9::chr1:174143249..174143260,-#_82ce2ac21a3ed20589eae8aee1e9078ep@chr1:174143249..174143260, -
3.03e-39FFCP PHASE1:Mm9::chr6:51525869..51525891,+#_4c1f34f08e73622d4c34d4b0260f9300p@chr6:51525869..51525891, +
3.03e-39FFCP PHASE2:Mm9::chr6:51525869..51525891,+#_4c1f34f08e73622d4c34d4b0260f9300p@chr6:51525869..51525891, +
9.31e-39FFCP PHASE1:Mm9::chr11:102130083..102130092,+#_6d9145e7ce1715b3f693c0658a9006f5p3@Asb16
9.31e-39FFCP PHASE2:Mm9::chr11:102130083..102130092,+#_6d9145e7ce1715b3f693c0658a9006f5p3@Asb16
2.41e-35FFCP PHASE1:Mm9::chr7:133604286..133604297,-#_3a7342f03c184f03655cb216b4cbad06p@chr7:133604286..133604297, -
2.41e-35FFCP PHASE2:Mm9::chr7:133604286..133604297,-#_3a7342f03c184f03655cb216b4cbad06p@chr7:133604286..133604297, -
2.95e-35FFCP PHASE1:Mm9::chr4:138365748..138365759,-#_44b6e3dbe9a2b4b36bd952f1a01ad1e7p5@Pla2g5
2.95e-35FFCP PHASE2:Mm9::chr4:138365748..138365759,-#_44b6e3dbe9a2b4b36bd952f1a01ad1e7p5@Pla2g5
9.53e-34FFCP PHASE2:Mm9::chr8:74049600..74049612,-#_fa7062e14773e55f2936816174c0c489p2@uc009mdq.1
9.53e-34FFCP PHASE1:Mm9::chr8:74049600..74049612,-#_fa7062e14773e55f2936816174c0c489p2@uc009mdq.1
1.23e-33FFCP PHASE1:Mm9::chr2:164773241..164773248,+#_08b5521573ccbe693548c121a07e3a5ep3@Mmp9
1.23e-33FFCP PHASE2:Mm9::chr2:164773241..164773248,+#_08b5521573ccbe693548c121a07e3a5ep3@Mmp9
1.58e-33FFCP PHASE1:Mm9::chr7:3567707..3567718,-#_ad3d7c74651f9cb260bd7c329e07c6b6p2@Oscar
1.58e-33FFCP PHASE2:Mm9::chr7:3567707..3567718,-#_ad3d7c74651f9cb260bd7c329e07c6b6p2@Oscar
1.58e-33FFCP PHASE1:Mm9::chr1:166815111..166815121,-#_ad3d7c74651f9cb260bd7c329e07c6b6p@chr1:166815111..166815121, -
1.58e-33FFCP PHASE2:Mm9::chr1:166815111..166815121,-#_ad3d7c74651f9cb260bd7c329e07c6b6p@chr1:166815111..166815121, -
2.04e-33FFCP PHASE2:Mm9::chr11:75409652..75409664,+#_97032a94cb7083218af512091980205dp@chr11:75409652..75409664, +
2.04e-33FFCP PHASE1:Mm9::chr9:70799951..70799962,-#_97032a94cb7083218af512091980205dp4@Lipc
2.04e-33FFCP PHASE2:Mm9::chr9:70799951..70799962,-#_97032a94cb7083218af512091980205dp4@Lipc
2.04e-33FFCP PHASE1:Mm9::chr11:75409652..75409664,+#_97032a94cb7083218af512091980205dp@chr11:75409652..75409664, +
3.38e-33FFCP PHASE1:Mm9::chr15:102196702..102196713,-#_b0c1ad921d6688281d3bcb853acad0bap6@Sp7
3.38e-33FFCP PHASE2:Mm9::chr15:102196702..102196713,-#_b0c1ad921d6688281d3bcb853acad0bap6@Sp7
7.17e-33FFCP PHASE1:Mm9::chr18:76271498..76271508,+#_d79d2ea46e27a70f1b1425053cc563bep@chr18:76271498..76271508, +
7.17e-33FFCP PHASE2:Mm9::chr18:76271498..76271508,+#_d79d2ea46e27a70f1b1425053cc563bep@chr18:76271498..76271508, +
7.17e-33FFCP PHASE1:Mm9::chr8:126415826..126415839,+#_d79d2ea46e27a70f1b1425053cc563bep@chr8:126415826..126415839, +
7.17e-33FFCP PHASE2:Mm9::chr8:126415826..126415839,+#_d79d2ea46e27a70f1b1425053cc563bep@chr8:126415826..126415839, +
2.67e-30FFCP PHASE1:Mm9::chr2:32482387..32482399,+#_b253433be0108db102f469984b90347cp@chr2:32482387..32482399, +
2.67e-30FFCP PHASE2:Mm9::chr2:32482387..32482399,+#_b253433be0108db102f469984b90347cp@chr2:32482387..32482399, +
1.1e-29FFCP PHASE2:Mm9::chr12:70396969..70396979,+#_ed77989eb67dad88f736c95c7f38d2d2p@chr12:70396969..70396979, +
1.1e-29FFCP PHASE1:Mm9::chr12:70396969..70396979,+#_ed77989eb67dad88f736c95c7f38d2d2p@chr12:70396969..70396979, +
1.1e-29FFCP PHASE2:Mm9::chr15:58649683..58649688,-#_ed77989eb67dad88f736c95c7f38d2d2p@chr15:58649683..58649688, -
1.1e-29FFCP PHASE1:Mm9::chr15:58649683..58649688,-#_ed77989eb67dad88f736c95c7f38d2d2p@chr15:58649683..58649688, -
1.46e-29FFCP PHASE2:Mm9::chr7:133590998..133591009,-#_11227fa48155dd5623764d90c5c25b38p@chr7:133590998..133591009, -
1.46e-29FFCP PHASE1:Mm9::chr7:133590998..133591009,-#_11227fa48155dd5623764d90c5c25b38p@chr7:133590998..133591009, -
1.73e-29FFCP PHASE2:Mm9::chr18:60751417..60751432,-#_27f11e159d835dc6ce6dbc22792aad39p2@Myoz3
1.73e-29FFCP PHASE1:Mm9::chr18:60751417..60751432,-#_27f11e159d835dc6ce6dbc22792aad39p2@Myoz3
2.42e-29FFCP PHASE2:Mm9::chr11:67051354..67051366,+#_15efc64329dd7b6e80b898743ddeffd3p2@Myh4
2.42e-29FFCP PHASE1:Mm9::chr11:67051354..67051366,+#_15efc64329dd7b6e80b898743ddeffd3p2@Myh4
7.46e-29FFCP PHASE2:Mm9::chr1:57155729..57155740,-#_3bebb7e2779cdc27672cc532c45c181cp@chr1:57155729..57155740, -
7.46e-29FFCP PHASE1:Mm9::chr1:57155729..57155740,-#_3bebb7e2779cdc27672cc532c45c181cp@chr1:57155729..57155740, -
9.26e-29FFCP PHASE2:Mm9::chr11:67056544..67056589,-#_5af86bea4954e52018f2f9802e24dbe4p@chr11:67056544..67056589, -
9.26e-29FFCP PHASE2:Mm9::chr4:43597258..43597265,-#_5af86bea4954e52018f2f9802e24dbe4p1@Msmp
9.26e-29FFCP PHASE1:Mm9::chr11:67056544..67056589,-#_5af86bea4954e52018f2f9802e24dbe4p@chr11:67056544..67056589, -
9.26e-29FFCP PHASE1:Mm9::chr4:43597258..43597265,-#_5af86bea4954e52018f2f9802e24dbe4p1@Msmp
1.15e-28FFCP PHASE2:Mm9::chrY:2858251..2858257,+#_f28cc19ca6a1e62daf953a4d5dd70877p@chrY:2858251..2858257, +
1.15e-28FFCP PHASE2:Mm9::chr6:90552017..90552024,+#_f28cc19ca6a1e62daf953a4d5dd70877p@chr6:90552017..90552024, +
1.15e-28FFCP PHASE1:Mm9::chr6:90552017..90552024,+#_f28cc19ca6a1e62daf953a4d5dd70877p@chr6:90552017..90552024, +
1.15e-28FFCP PHASE1:Mm9::chrY:2858251..2858257,+#_f28cc19ca6a1e62daf953a4d5dd70877p@chrY:2858251..2858257, +
1.43e-28FFCP PHASE2:Mm9::chr6:34436258..34436292,+#_dab350db5b74f17f1054a6278430174dp@chr6:34436258..34436292, +
1.43e-28FFCP PHASE1:Mm9::chr6:34436258..34436292,+#_dab350db5b74f17f1054a6278430174dp@chr6:34436258..34436292, +
2.2e-28FFCP PHASE2:Mm9::chr11:67069796..67069817,-#_9c3e0fcb5f8cb5cfdc5ef9cde561a426p@chr11:67069796..67069817, -
2.2e-28FFCP PHASE1:Mm9::chr11:67069796..67069817,-#_9c3e0fcb5f8cb5cfdc5ef9cde561a426p@chr11:67069796..67069817, -
2.72e-28FFCP PHASE2:Mm9::chr8:107702369..107702386,+#_da41467e3cc2aa8869d9d9f4dc1f9815p@chr8:107702369..107702386, +
2.72e-28FFCP PHASE1:Mm9::chr8:107702369..107702386,+#_da41467e3cc2aa8869d9d9f4dc1f9815p@chr8:107702369..107702386, +
3.45e-28FFCP PHASE1:Mm9::chr18:78254135..78254146,-#_1a8aa412732d3268ee666ee14c7cada1p1@Siglec15
3.45e-28FFCP PHASE2:Mm9::chr18:78254135..78254146,-#_1a8aa412732d3268ee666ee14c7cada1p1@Siglec15
6.5e-28FFCP PHASE1:Mm9::chr7:133591490..133591500,-#_4d4c970f6201cb9cade857eae3f8b4cfp6@Atp2a1
6.5e-28FFCP PHASE2:Mm9::chr7:133591490..133591500,-#_4d4c970f6201cb9cade857eae3f8b4cfp6@Atp2a1
8.9e-28FFCP PHASE2:Mm9::chr7:133591156..133591165,-#_e5f711b727ab838ca4ad042f254b7479p7@Atp2a1
8.9e-28FFCP PHASE1:Mm9::chr7:133591156..133591165,-#_e5f711b727ab838ca4ad042f254b7479p7@Atp2a1
1.42e-27FFCP PHASE2:Mm9::chr7:133600635..133600663,+#_d0411d7a7804860928ff2f3f43d96eacp@chr7:133600635..133600663, +
1.42e-27FFCP PHASE1:Mm9::chr7:133600635..133600663,+#_d0411d7a7804860928ff2f3f43d96eacp@chr7:133600635..133600663, +
1.42e-27FFCP PHASE2:Mm9::chr7:133592162..133592188,-#_d0411d7a7804860928ff2f3f43d96eacp@chr7:133592162..133592188, -
1.42e-27FFCP PHASE1:Mm9::chr7:133592162..133592188,-#_d0411d7a7804860928ff2f3f43d96eacp@chr7:133592162..133592188, -
6.75e-27FFCP PHASE2:Mm9::chr11:94837662..94837673,-#_696a7e38072b51d586276af2f3c7a42bp4@Sgca
6.75e-27FFCP PHASE1:Mm9::chr11:94837662..94837673,-#_696a7e38072b51d586276af2f3c7a42bp4@Sgca
1.66e-26FFCP PHASE1:Mm9::chr5:104754379..104754387,+#_2a81888f46ac23679f3b6766c920c7d1p1@Mepe
1.66e-26FFCP PHASE2:Mm9::chr5:104754379..104754387,+#_2a81888f46ac23679f3b6766c920c7d1p1@Mepe
3.47e-26FFCP PHASE1:Mm9::chr16:32400888..32400899,+#_0d0c71a61da0348b9c543e0d8d8183e5p2@Tm4sf19
3.47e-26FFCP PHASE2:Mm9::chr12:81581216..81581231,+#_0d0c71a61da0348b9c543e0d8d8183e5p@chr12:81581216..81581231, +
3.47e-26FFCP PHASE2:Mm9::chr16:32400888..32400899,+#_0d0c71a61da0348b9c543e0d8d8183e5p2@Tm4sf19
3.47e-26FFCP PHASE1:Mm9::chr12:81581216..81581231,+#_0d0c71a61da0348b9c543e0d8d8183e5p@chr12:81581216..81581231, +
1.12e-25FFCP PHASE2:Mm9::chr17:34176173..34176200,+#_5c7a7e55ddcd4d35b16146ed08cb07f6p5@Col11a2
1.12e-25FFCP PHASE1:Mm9::chr15:97806574..97806585,-#_5c7a7e55ddcd4d35b16146ed08cb07f6p@chr15:97806574..97806585, -
1.12e-25FFCP PHASE2:Mm9::chr15:97806574..97806585,-#_5c7a7e55ddcd4d35b16146ed08cb07f6p@chr15:97806574..97806585, -
1.12e-25FFCP PHASE1:Mm9::chr17:34176173..34176200,+#_5c7a7e55ddcd4d35b16146ed08cb07f6p5@Col11a2
1.36e-25FFCP PHASE2:Mm9::chr2:180890942..180890956,-#_e54a05906d2de3631a7a89d1c3eb51e1p@chr2:180890942..180890956, -
1.36e-25FFCP PHASE1:Mm9::chr2:180890942..180890956,-#_e54a05906d2de3631a7a89d1c3eb51e1p@chr2:180890942..180890956, -

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