MCL coexpression mm9:2539
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:13685585..13685645,+ | p2@Hivep2 |
| Mm9::chr10:13685899..13685916,+ | p1@Hivep2 |
| Mm9::chrX:12339216..12339239,- | p4@Med14 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0044451 | nucleoplasm part | 0.0202373801242691 |
| GO:0005654 | nucleoplasm | 0.0202373801242691 |
| GO:0031981 | nuclear lumen | 0.0202373801242691 |
| GO:0031974 | membrane-enclosed lumen | 0.0202373801242691 |
| GO:0043233 | organelle lumen | 0.0202373801242691 |
| GO:0000119 | mediator complex | 0.0241471748558044 |
| GO:0044428 | nuclear part | 0.0255491761587703 |
| GO:0016591 | DNA-directed RNA polymerase II, holoenzyme | 0.0414820964828024 |
| GO:0043234 | protein complex | 0.0414820964828024 |
| GO:0003713 | transcription coactivator activity | 0.0414820964828024 |
| GO:0006355 | regulation of transcription, DNA-dependent | 0.0414820964828024 |
| GO:0006351 | transcription, DNA-dependent | 0.0414820964828024 |
| GO:0032774 | RNA biosynthetic process | 0.0414820964828024 |
| GO:0045449 | regulation of transcription | 0.0414820964828024 |
| GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0414820964828024 |
| GO:0006350 | transcription | 0.0414820964828024 |
| GO:0032991 | macromolecular complex | 0.0414820964828024 |
| GO:0010468 | regulation of gene expression | 0.0414820964828024 |
| GO:0031323 | regulation of cellular metabolic process | 0.0414820964828024 |
| GO:0019222 | regulation of metabolic process | 0.0414820964828024 |
| GO:0016070 | RNA metabolic process | 0.0414820964828024 |
| GO:0003712 | transcription cofactor activity | 0.0414820964828024 |
| GO:0044446 | intracellular organelle part | 0.0414820964828024 |
| GO:0044422 | organelle part | 0.0414820964828024 |
| GO:0016563 | transcription activator activity | 0.0483065873043917 |
| GO:0008134 | transcription factor binding | 0.0483065873043917 |
| GO:0010467 | gene expression | 0.0483065873043917 |
| GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 0.0483065873043917 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| neuron | 3.12e-07 | 33 |
| neuronal stem cell | 3.12e-07 | 33 |
| neuroblast | 3.12e-07 | 33 |
| electrically signaling cell | 3.12e-07 | 33 |
| Ontology term | p-value | n |
|---|---|---|
| gray matter | 2.94e-13 | 34 |
| organ part | 1.86e-12 | 99 |
| brain grey matter | 1.12e-11 | 29 |
| regional part of telencephalon | 1.12e-11 | 29 |
| telencephalon | 1.12e-11 | 29 |
| cerebral cortex | 6.12e-11 | 21 |
| cerebral hemisphere | 6.12e-11 | 21 |
| pallium | 6.12e-11 | 21 |
| nervous system | 1.26e-10 | 75 |
| regional part of nervous system | 1.40e-10 | 54 |
| central nervous system | 1.96e-10 | 73 |
| neural tube | 4.30e-10 | 52 |
| neural rod | 4.30e-10 | 52 |
| future spinal cord | 4.30e-10 | 52 |
| neural keel | 4.30e-10 | 52 |
| ectoderm-derived structure | 1.57e-09 | 95 |
| ectoderm | 1.57e-09 | 95 |
| presumptive ectoderm | 1.57e-09 | 95 |
| brain | 4.29e-09 | 47 |
| future brain | 4.29e-09 | 47 |
| regional part of forebrain | 1.05e-08 | 39 |
| forebrain | 1.05e-08 | 39 |
| future forebrain | 1.05e-08 | 39 |
| regional part of cerebral cortex | 1.07e-08 | 17 |
| anterior neural tube | 1.22e-08 | 40 |
| ecto-epithelium | 1.24e-08 | 73 |
| regional part of brain | 1.44e-08 | 46 |
| occipital lobe | 4.47e-08 | 10 |
| visual cortex | 4.47e-08 | 10 |
| neocortex | 4.47e-08 | 10 |
| neurectoderm | 4.80e-08 | 64 |
| neural plate | 4.80e-08 | 64 |
| presumptive neural plate | 4.80e-08 | 64 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.526413 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 1.46714 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 2.60474 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 0.61552 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 0.190475 |
| MA0056.1 | 0 |
| MA0057.1 | 0.896032 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.908538 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.680038 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 0.657929 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 0.27999 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 0.762845 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 1.04599 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 1.54626 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 0.462282 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 1.33779 |
| MA0145.1 | 0.794492 |
| MA0146.1 | 0.151124 |
| MA0147.1 | 0.556853 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 1.71612 |
| MA0062.2 | 1.06145 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 0.71803 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.29236 |
| MA0065.2 | 0.79573 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 0.312898 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 0.964824 |
| MA0163.1 | 0.157796 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 3.96489 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
