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|full_id=C2973_Mesenchymal_Alveolar_Renal_Pericytes_Hepatic_Smooth_Astrocyte
|full_id=C2973_Mesenchymal_Alveolar_Renal_Pericytes_Hepatic_Smooth_Astrocyte
|id=C2973
|id=C2973
|ontology_enrichment_celltype=CL:0002321!7.44e-31!248;CL:0000220!1.63e-30!246;CL:0000222!1.30e-25!119;CL:0000055!2.69e-23!180;CL:0000183!1.21e-17!59;CL:0000393!2.66e-16!60;CL:0000211!2.66e-16!60;CL:0000680!8.32e-15!57;CL:0000056!8.32e-15!57;CL:0000355!8.32e-15!57;CL:0000187!9.51e-15!54;CL:0002078!3.09e-12!44;CL:0000192!7.97e-12!42;CL:0000514!7.97e-12!42;CL:0000115!1.37e-11!35;CL:0000359!5.59e-10!32;CL:0002139!1.17e-09!24;CL:0000213!2.20e-09!57;CL:0000215!2.20e-09!57;CL:1000449!8.45e-09!16;CL:0000221!9.24e-09!71;CL:0000071!1.01e-08!18;CL:0002546!1.01e-08!18;CL:0002681!1.00e-07!13;CL:0002584!1.00e-07!13;CL:0000133!5.97e-07!59;CL:1000507!6.66e-07!12;CL:1000494!6.66e-07!12
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000119!4.10e-31!312;UBERON:0000483!1.03e-30!309;UBERON:0000475!2.52e-23!365;UBERON:0002049!9.08e-21!79;UBERON:0007798!9.08e-21!79;UBERON:0000486!1.48e-19!82;UBERON:0000481!6.01e-19!347;UBERON:0000914!8.70e-19!83;UBERON:0002329!8.70e-19!83;UBERON:0003077!8.70e-19!83;UBERON:0003059!8.70e-19!83;UBERON:0007282!8.70e-19!83;UBERON:0009618!8.70e-19!83;UBERON:0007285!8.70e-19!83;UBERON:0004290!3.35e-18!70;UBERON:0005256!4.61e-18!143;UBERON:0000025!9.29e-18!194;UBERON:0003914!3.72e-17!118;UBERON:0001134!1.18e-16!61;UBERON:0002036!1.18e-16!61;UBERON:0003082!1.18e-16!61;UBERON:0000055!4.80e-16!69;UBERON:0004111!7.57e-16!241;UBERON:0000477!1.10e-15!286;UBERON:0000490!2.48e-15!138;UBERON:0002385!2.69e-15!63;UBERON:0001015!2.69e-15!63;UBERON:0000383!2.69e-15!63;UBERON:0004872!4.38e-15!84;UBERON:0001981!7.81e-15!60;UBERON:0007500!7.81e-15!60;UBERON:0004537!7.81e-15!60;UBERON:0006965!7.81e-15!60;UBERON:0002100!3.57e-13!216;UBERON:0001009!1.40e-11!113;UBERON:0001637!2.16e-11!42;UBERON:0003509!2.16e-11!42;UBERON:0004572!2.16e-11!42;UBERON:0004535!2.51e-11!110;UBERON:0000064!5.65e-11!219;UBERON:0000924!8.33e-11!173;UBERON:0006601!8.33e-11!173;UBERON:0000468!1.00e-10!659;UBERON:0004121!1.50e-10!169;UBERON:0003104!2.78e-10!238;UBERON:0009142!2.78e-10!238;UBERON:0004211!8.45e-09!16;UBERON:0001285!8.45e-09!16;UBERON:0007684!8.45e-09!16;UBERON:0003220!8.45e-09!16;UBERON:0004208!8.45e-09!16;UBERON:0001986!1.01e-08!18;UBERON:0004638!1.01e-08!18;UBERON:0004852!1.01e-08!18;UBERON:0000922!1.52e-08!612;UBERON:0006555!2.03e-08!17;UBERON:0005103!2.03e-08!17;UBERON:0000083!2.03e-08!17;UBERON:0009201!2.03e-08!17;UBERON:0004819!2.03e-08!17;UBERON:0006553!2.03e-08!17;UBERON:0003074!2.03e-08!17;UBERON:0003060!2.03e-08!17;UBERON:0000353!2.63e-08!17;UBERON:0006914!5.54e-08!25;UBERON:0000487!5.56e-08!22;UBERON:0004573!5.92e-08!33;UBERON:0004571!5.92e-08!33;UBERON:0000467!6.02e-08!625;UBERON:0000033!6.56e-08!123;UBERON:0002050!9.03e-08!605;UBERON:0005423!9.03e-08!605;UBERON:0001225!1.00e-07!13;UBERON:0008987!1.00e-07!13;UBERON:0000480!1.07e-07!626;UBERON:0003103!1.36e-07!69;UBERON:0000923!1.38e-07!604;UBERON:0005291!1.38e-07!604;UBERON:0006598!1.38e-07!604;UBERON:0002532!1.38e-07!604;UBERON:0000080!2.03e-07!18;UBERON:0002120!2.03e-07!18;UBERON:0004875!2.03e-07!18;UBERON:0005721!2.03e-07!18;UBERON:0005754!2.03e-07!18;UBERON:0007297!2.03e-07!18;UBERON:0004876!2.19e-07!20;UBERON:0000153!2.87e-07!129;UBERON:0007811!2.87e-07!129;UBERON:0000073!4.16e-07!94;UBERON:0001016!4.16e-07!94;UBERON:0009773!6.66e-07!12;UBERON:0001231!6.66e-07!12;UBERON:0004810!6.66e-07!12
}}
}}

Revision as of 14:30, 21 May 2012


Full id: C2973_Mesenchymal_Alveolar_Renal_Pericytes_Hepatic_Smooth_Astrocyte



Phase1 CAGE Peaks

Hg19::chr10:104192322..104192379,-p1@CUEDC2
Hg19::chr2:242447962..242447981,-p3@STK25
Hg19::chr2:242447983..242448034,-p1@STK25


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
embryonic cell7.44e-31248
mesodermal cell1.30e-25119
non-terminally differentiated cell2.69e-23180
contractile cell1.21e-1759
electrically responsive cell2.66e-1660
electrically active cell2.66e-1660
muscle precursor cell8.32e-1557
myoblast8.32e-1557
multi-potent skeletal muscle stem cell8.32e-1557
muscle cell9.51e-1554
meso-epithelial cell3.09e-1244
smooth muscle cell7.97e-1242
smooth muscle myoblast7.97e-1242
endothelial cell1.37e-1135
vascular associated smooth muscle cell5.59e-1032
endothelial cell of vascular tree1.17e-0924
lining cell2.20e-0957
barrier cell2.20e-0957
epithelial cell of nephron8.45e-0916
ectodermal cell9.24e-0971
blood vessel endothelial cell1.01e-0818
embryonic blood vessel endothelial progenitor cell1.01e-0818
kidney cortical cell1.00e-0713
renal cortical epithelial cell1.00e-0713
neurectodermal cell5.97e-0759
kidney tubule cell6.66e-0712
nephron tubule epithelial cell6.66e-0712
Uber Anatomy
Ontology termp-valuen
cell layer4.10e-31312
epithelium1.03e-30309
organism subdivision2.52e-23365
vasculature9.08e-2179
vascular system9.08e-2179
multilaminar epithelium1.48e-1982
multi-tissue structure6.01e-19347
somite8.70e-1983
paraxial mesoderm8.70e-1983
presomitic mesoderm8.70e-1983
presumptive segmental plate8.70e-1983
trunk paraxial mesoderm8.70e-1983
presumptive paraxial mesoderm8.70e-1983
dermomyotome3.35e-1870
trunk mesenchyme4.61e-18143
tube9.29e-18194
epithelial tube3.72e-17118
skeletal muscle tissue1.18e-1661
striated muscle tissue1.18e-1661
myotome1.18e-1661
vessel4.80e-1669
anatomical conduit7.57e-16241
anatomical cluster1.10e-15286
unilaminar epithelium2.48e-15138
muscle tissue2.69e-1563
musculature2.69e-1563
musculature of body2.69e-1563
splanchnic layer of lateral plate mesoderm4.38e-1584
blood vessel7.81e-1560
epithelial tube open at both ends7.81e-1560
blood vasculature7.81e-1560
vascular cord7.81e-1560
trunk3.57e-13216
circulatory system1.40e-11113
artery2.16e-1142
arterial blood vessel2.16e-1142
arterial system2.16e-1142
cardiovascular system2.51e-11110
organ part5.65e-11219
ectoderm8.33e-11173
presumptive ectoderm8.33e-11173
multi-cellular organism1.00e-10659
ectoderm-derived structure1.50e-10169
mesenchyme2.78e-10238
entire embryonic mesenchyme2.78e-10238
nephron epithelium8.45e-0916
nephron8.45e-0916
uriniferous tubule8.45e-0916
metanephric mesenchyme8.45e-0916
nephrogenic mesenchyme8.45e-0916
endothelium1.01e-0818
blood vessel endothelium1.01e-0818
cardiovascular system endothelium1.01e-0818
embryo1.52e-08612
excretory tube2.03e-0817
mesonephric epithelium2.03e-0817
mesonephric tubule2.03e-0817
nephric duct2.03e-0817
kidney epithelium2.03e-0817
renal duct2.03e-0817
mesonephric duct2.03e-0817
pronephric duct2.03e-0817
parenchyma2.63e-0817
squamous epithelium5.54e-0825
simple squamous epithelium5.56e-0822
systemic artery5.92e-0833
systemic arterial system5.92e-0833
anatomical system6.02e-08625
head6.56e-08123
embryonic structure9.03e-08605
developing anatomical structure9.03e-08605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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