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|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!7.50e-26!102;UBERON:0003061!7.50e-26!102;UBERON:0002193!2.38e-23!112;UBERON:0002371!2.18e-17!80;UBERON:0002384!7.93e-16!375;UBERON:0001474!1.22e-15!86;UBERON:0004765!1.19e-13!101;UBERON:0001434!1.19e-13!101;UBERON:0002405!6.69e-10!115;UBERON:0000178!4.20e-08!15;UBERON:0000179!4.20e-08!15;UBERON:0000463!4.20e-08!15
|ontology_enrichment_uberon=UBERON:0002390!7.50e-26!102;UBERON:0003061!7.50e-26!102;UBERON:0002193!2.38e-23!112;UBERON:0002371!2.18e-17!80;UBERON:0002384!7.93e-16!375;UBERON:0001474!1.22e-15!86;UBERON:0004765!1.19e-13!101;UBERON:0001434!1.19e-13!101;UBERON:0002405!6.69e-10!115;UBERON:0000178!4.20e-08!15;UBERON:0000179!4.20e-08!15;UBERON:0000463!4.20e-08!15
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}}
}}

Revision as of 19:11, 8 August 2012


Full id: C3460_Mast_CD14_malignant_Neutrophils_epidermoid_Smooth_squamous



Phase1 CAGE Peaks

Hg19::chr14:91581610..91581632,-p@chr14:91581610..91581632
-
Hg19::chr7:92747245..92747252,-p3@SAMD9
Hg19::chr7:92747269..92747332,-p1@SAMD9


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
leukocyte2.18e-39140
hematopoietic stem cell4.40e-38172
angioblastic mesenchymal cell4.40e-38172
hematopoietic oligopotent progenitor cell1.72e-36165
hematopoietic multipotent progenitor cell1.72e-36165
hematopoietic lineage restricted progenitor cell2.09e-36124
nongranular leukocyte5.00e-35119
hematopoietic cell5.06e-34182
myeloid leukocyte1.97e-2276
myeloid lineage restricted progenitor cell3.29e-2070
myeloid cell1.61e-19112
common myeloid progenitor1.61e-19112
granulocyte monocyte progenitor cell1.56e-1871
CD14-positive, CD16-negative classical monocyte1.56e-1842
classical monocyte5.82e-1845
monopoietic cell1.40e-1763
monocyte1.40e-1763
monoblast1.40e-1763
promonocyte1.40e-1763
mesenchymal cell1.42e-17358
macrophage dendritic cell progenitor4.61e-1765
lymphocyte3.59e-1653
common lymphoid progenitor3.59e-1653
lymphoid lineage restricted progenitor cell3.93e-1652
connective tissue cell4.73e-16365
motile cell2.51e-12390
multi fate stem cell7.62e-11430
somatic stem cell2.48e-10436
stem cell1.83e-09444
lymphocyte of B lineage3.50e-0824
pro-B cell3.50e-0824
T cell4.92e-0825
pro-T cell4.92e-0825
mature alpha-beta T cell6.45e-0818
alpha-beta T cell6.45e-0818
immature T cell6.45e-0818
mature T cell6.45e-0818
immature alpha-beta T cell6.45e-0818
native cell7.72e-07722
Uber Anatomy
Ontology termp-valuen
hematopoietic system7.50e-26102
blood island7.50e-26102
hemolymphoid system2.38e-23112
bone marrow2.18e-1780
connective tissue7.93e-16375
bone element1.22e-1586
skeletal element1.19e-13101
skeletal system1.19e-13101
immune system6.69e-10115
blood4.20e-0815
haemolymphatic fluid4.20e-0815
organism substance4.20e-0815


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.