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|coexpression_dpi_cluster_scores_median=0.064513712786576,0,0,0,0,0,0,-0.0558273534811859,0,0,-0.0276995656725672,0,-0.0779487001066754,-0.119195658125221,0,0,0,0,0,0,0.151228062650159,-0.0248624046345376,0,-0.0657676456332082,0,0,-0.0423166123487502,0,0,0,0,-0.107031774808249,0,-0.145480126286698,0,-0.0175132113954451,-0.0560219014108476,0,0,0,-0.145480126286698,0,0,0,0,0,0,0.0116895296165529,0,0,0,0,-0.0938619070603188,0,0,0,0,0.0666988545529166,0.173238565069731,0.159684323995332,0.213207239280454,0,0,0,0,0,0,0,0.0428469550828748,0.0704659263841801,0.0224947235419768,0.433594786201484,0.350941077102203,0.0696309751379102,0.0397493170902889,0,0.322458878535173,0.403506246574079,0.440124545030544,0.177134701665477,0.135434985107224,0.111248819918424,0.387448156917739,0.355682312955468,0.402774059390807,0.338160423388235,0.432722453268321,0.241944181742968,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0.0572260417947564,0,0,0,-0.0705731179100352,-0.0575173513908583,-0.0435683480271069,0,0,0,0,0.0337492525987433,0.0518147637201475,0.014802560181808,0.0747602270245177,0,0,0.0586534975690397,0,0.0712312450493009,0,0,0,0.271579486615472,0.353470026308997,0,-0.0623009700008221,0,-0.015333207005935,0.477828604579405,0.451786805560604,0.177068925090124,0.647421403211826,0.660867033365574,0.457895878829497,0.492639778042444,0.00292429182450099,0,0,0.017370001175398,0,0,0,0.0593081123026218,0.09716104180496,0.0523528812100954,0.0991943601425233,0,0,0,0,0,0,0,0.0322568572292507,0,-0.0811712996189286,-0.056137671960836,-0.0469728136704901,0.274161379305899,0.253981976924931,0.278824523977366,0.339197683142509,0.41062775199393,0.497876669225483,0.423092748838171,0.617719728633141,0.566508537956114,0.619110596366052,0.694306783465608,0.691439762777669,0.739051757498119,0.680396641601037,0.664129143879435,0.515133036123758,0.173184029861082,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0294389011296462,0.0266298923127834,0,0.0351068516428422,0,0,0,-0.0149074406337142,0,-0.0652649993966822,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0418006685190215,0,0.0382879833669989,0.0368639442616132,0,0.0567384756119329,0.044709968083771,0.0642538110976656,0,0.00474129958265954,0,0,0,0,-0.0502541445577134,0.391641981893883,0.402046663331577,0,0.0977676536600382,0,0,0,0,0,0,0,0.0443023195007269,0,0.511783022680149,0.0301482956841874,0,0.00544857665814136,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0539669150628399,0,0.028767862613093,0.0820795120556661,-0.0539286296867064,-0.0721506933766315,0,0,0,0.0254340553719351,0,0,0,0.37722860212252,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.00139819147959508,0,0,0.034489466458534,0,0,0,-0.155593135195239,0,0,0,0.0216799586183926,0,0.0481920468563092,0.0177496125214138,0,0,0,0,-0.00119663208713899,0,0,0,0,0,0,-0.0021934806115283,0,0,0,0,0,0.162403313502186,-0.0685269214386177,-0.0551250350902459,-0.135037380015351,0.0767094571656325,0,0,0,0,0.680262602238555,0.670487236271907,0.706399236414067,0.637233033489871,0.645953767926874,0.646964123768169,0.630083419537236,0.552443940605386,0.570409181558021,0.56819919407737,0,0,0.0240163332436021,0.0945084131504676,0.0826465040380816,0.132725326823584,0.0871588832444397,0.081359932135904,0.120876255993453,0.17765030293269,0.0962858827766526,0.134526261473315,0.107523539997041,0.0990244263857601,0.125696534369219,0.0775617666324684,0.129578075275077,0.157395619547506,0.14986111676545,0.0753818739155043,0.0502440154234497,0.0893163289114565,0.092873634605593,0.114555918810875,0.10799917315244,0.126604887871452,0.135404897539632,0.101427320830301,0.0934076540779607,0.139531591397739,0.200349806575294,0.112441925220423,0.148982201447044,0.129878892306899,0,0.175981558593572,0.091291089277545,0.123912370014482,0.145986775800071,0.0865703124974023,0.0905641158318875
|coexpression_dpi_cluster_scores_median=0.064513712786576,0,0,0,0,0,0,-0.0558273534811859,0,0,-0.0276995656725672,0,-0.0779487001066754,-0.119195658125221,0,0,0,0,0,0,0.151228062650159,-0.0248624046345376,0,-0.0657676456332082,0,0,-0.0423166123487502,0,0,0,0,-0.107031774808249,0,-0.145480126286698,0,-0.0175132113954451,-0.0560219014108476,0,0,0,-0.145480126286698,0,0,0,0,0,0,0.0116895296165529,0,0,0,0,-0.0938619070603188,0,0,0,0,0.0666988545529166,0.173238565069731,0.159684323995332,0.213207239280454,0,0,0,0,0,0,0,0.0428469550828748,0.0704659263841801,0.0224947235419768,0.433594786201484,0.350941077102203,0.0696309751379102,0.0397493170902889,0,0.322458878535173,0.403506246574079,0.440124545030544,0.177134701665477,0.135434985107224,0.111248819918424,0.387448156917739,0.355682312955468,0.402774059390807,0.338160423388235,0.432722453268321,0.241944181742968,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0.0572260417947564,0,0,0,-0.0705731179100352,-0.0575173513908583,-0.0435683480271069,0,0,0,0,0.0337492525987433,0.0518147637201475,0.014802560181808,0.0747602270245177,0,0,0.0586534975690397,0,0.0712312450493009,0,0,0,0.271579486615472,0.353470026308997,0,-0.0623009700008221,0,-0.015333207005935,0.477828604579405,0.451786805560604,0.177068925090124,0.647421403211826,0.660867033365574,0.457895878829497,0.492639778042444,0.00292429182450099,0,0,0.017370001175398,0,0,0,0.0593081123026218,0.09716104180496,0.0523528812100954,0.0991943601425233,0,0,0,0,0,0,0,0.0322568572292507,0,-0.0811712996189286,-0.056137671960836,-0.0469728136704901,0.274161379305899,0.253981976924931,0.278824523977366,0.339197683142509,0.41062775199393,0.497876669225483,0.423092748838171,0.617719728633141,0.566508537956114,0.619110596366052,0.694306783465608,0.691439762777669,0.739051757498119,0.680396641601037,0.664129143879435,0.515133036123758,0.173184029861082,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0294389011296462,0.0266298923127834,0,0.0351068516428422,0,0,0,-0.0149074406337142,0,-0.0652649993966822,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0418006685190215,0,0.0382879833669989,0.0368639442616132,0,0.0567384756119329,0.044709968083771,0.0642538110976656,0,0.00474129958265954,0,0,0,0,-0.0502541445577134,0.391641981893883,0.402046663331577,0,0.0977676536600382,0,0,0,0,0,0,0,0.0443023195007269,0,0.511783022680149,0.0301482956841874,0,0.00544857665814136,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0539669150628399,0,0.028767862613093,0.0820795120556661,-0.0539286296867064,-0.0721506933766315,0,0,0,0.0254340553719351,0,0,0,0.37722860212252,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.00139819147959508,0,0,0.034489466458534,0,0,0,-0.155593135195239,0,0,0,0.0216799586183926,0,0.0481920468563092,0.0177496125214138,0,0,0,0,-0.00119663208713899,0,0,0,0,0,0,-0.0021934806115283,0,0,0,0,0,0.162403313502186,-0.0685269214386177,-0.0551250350902459,-0.135037380015351,0.0767094571656325,0,0,0,0,0.680262602238555,0.670487236271907,0.706399236414067,0.637233033489871,0.645953767926874,0.646964123768169,0.630083419537236,0.552443940605386,0.570409181558021,0.56819919407737,0,0,0.0240163332436021,0.0945084131504676,0.0826465040380816,0.132725326823584,0.0871588832444397,0.081359932135904,0.120876255993453,0.17765030293269,0.0962858827766526,0.134526261473315,0.107523539997041,0.0990244263857601,0.125696534369219,0.0775617666324684,0.129578075275077,0.157395619547506,0.14986111676545,0.0753818739155043,0.0502440154234497,0.0893163289114565,0.092873634605593,0.114555918810875,0.10799917315244,0.126604887871452,0.135404897539632,0.101427320830301,0.0934076540779607,0.139531591397739,0.200349806575294,0.112441925220423,0.148982201447044,0.129878892306899,0,0.175981558593572,0.091291089277545,0.123912370014482,0.145986775800071,0.0865703124974023,0.0905641158318875
|gostat_on_MCL_coexpression=GO:0005218;intracellular ligand-gated calcium channel activity;0.0352514829974452;20191!GO:0014074;response to purine;0.0352514829974452;20191!GO:0005219;ryanodine-sensitive calcium-release channel activity;0.0352514829974452;20191!GO:0031000;response to caffeine;0.0352514829974452;20191!GO:0046873;metal ion transmembrane transporter activity;0.0352514829974452;16519,11938,20191!GO:0004691;cAMP-dependent protein kinase activity;0.0471455207305244;18747!GO:0030001;metal ion transport;0.0471455207305244;16519,11938,20191!GO:0015467;G-protein activated inward rectifier potassium channel activity;0.0471455207305244;16519!GO:0000209;protein polyubiquitination;0.0471455207305244;17237!GO:0006816;calcium ion transport;0.0471455207305244;11938,20191!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.0471455207305244;18747!GO:0015278;calcium-release channel activity;0.0471455207305244;20191!GO:0050811;GABA receptor binding;0.0471455207305244;70827!GO:0008324;cation transmembrane transporter activity;0.0471455207305244;16519,11938,20191!GO:0006812;cation transport;0.0471455207305244;16519,11938,20191!GO:0015674;di-, tri-valent inorganic cation transport;0.0499393897011789;11938,20191!
|gostat_on_MCL_coexpression=GO:0005218;intracellular ligand-gated calcium channel activity;0.0352514829974452;20191!GO:0014074;response to purine;0.0352514829974452;20191!GO:0005219;ryanodine-sensitive calcium-release channel activity;0.0352514829974452;20191!GO:0031000;response to caffeine;0.0352514829974452;20191!GO:0046873;metal ion transmembrane transporter activity;0.0352514829974452;16519,11938,20191!GO:0004691;cAMP-dependent protein kinase activity;0.0471455207305244;18747!GO:0030001;metal ion transport;0.0471455207305244;16519,11938,20191!GO:0015467;G-protein activated inward rectifier potassium channel activity;0.0471455207305244;16519!GO:0000209;protein polyubiquitination;0.0471455207305244;17237!GO:0006816;calcium ion transport;0.0471455207305244;11938,20191!GO:0004690;cyclic nucleotide-dependent protein kinase activity;0.0471455207305244;18747!GO:0015278;calcium-release channel activity;0.0471455207305244;20191!GO:0050811;GABA receptor binding;0.0471455207305244;70827!GO:0008324;cation transmembrane transporter activity;0.0471455207305244;16519,11938,20191!GO:0006812;cation transport;0.0471455207305244;16519,11938,20191!GO:0015674;di-, tri-valent inorganic cation transport;0.0499393897011789;11938,20191!
|ontology_enrichment_celltype=CL:0000117!8.42e-10!23;CL:0000337!8.42e-10!23
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0010314!5.26e-25!92;UBERON:0000073!1.86e-18!54;UBERON:0001049!3.19e-17!52;UBERON:0005068!3.19e-17!52;UBERON:0006241!3.19e-17!52;UBERON:0007135!3.19e-17!52;UBERON:0001017!5.52e-16!73;UBERON:0002020!1.75e-15!34;UBERON:0001016!3.23e-15!75;UBERON:0002346!4.41e-15!64;UBERON:0003075!4.41e-15!64;UBERON:0007284!4.41e-15!64;UBERON:0000955!1.93e-14!47;UBERON:0006238!1.93e-14!47;UBERON:0004111!4.39e-14!122;UBERON:0000025!6.83e-14!114;UBERON:0002616!8.38e-14!46;UBERON:0004121!6.03e-13!95;UBERON:0000924!6.03e-13!95;UBERON:0006601!6.03e-13!95;UBERON:0010371!6.40e-13!73;UBERON:0003528!1.34e-12!29;UBERON:0002791!1.34e-12!29;UBERON:0001893!1.34e-12!29;UBERON:0003080!4.32e-12!40;UBERON:0002780!1.73e-11!39;UBERON:0001890!1.73e-11!39;UBERON:0006240!1.73e-11!39;UBERON:0003056!2.22e-11!49;UBERON:0007100!8.41e-10!18;UBERON:0000948!8.41e-10!18;UBERON:0005498!8.41e-10!18;UBERON:0004140!8.41e-10!18;UBERON:0009881!8.41e-10!18;UBERON:0004141!8.41e-10!18;UBERON:0003084!8.41e-10!18;UBERON:0007005!8.41e-10!18;UBERON:0004139!8.41e-10!18;UBERON:0004291!8.41e-10!18;UBERON:0002021!5.93e-09!10;UBERON:0000411!5.93e-09!10;UBERON:0001950!5.93e-09!10;UBERON:0000956!1.27e-08!21;UBERON:0001869!1.27e-08!21;UBERON:0000203!1.27e-08!21;UBERON:0002619!1.21e-07!17;UBERON:0004535!1.82e-07!23;UBERON:0001009!1.82e-07!23
}}
}}

Revision as of 20:38, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr13:12199124..12199135,-p3@Ryr2
Mm9::chr13:12199136..12199148,-p4@Ryr2
Mm9::chr13:12199242..12199251,-p5@Ryr2
Mm9::chr15:99079365..99079378,-p5@Mcrs1
Mm9::chr15:99079383..99079403,-p2@Mcrs1
Mm9::chr16:4886302..4886320,+p3@Mgrn1
Mm9::chr17:43938737..43938766,+p4@Rcan2
Mm9::chr18:24867811..24867826,+p4@Fhod3
Mm9::chr19:34736884..34736923,-p1@Gm14446
Mm9::chr19:7061950..7062007,-p2@Vegfb
Mm9::chr1:59030230..59030241,-p7@Trak2
Mm9::chr2:55288199..55288212,+p4@Kcnj3
Mm9::chr3:32716442..32716498,+p4@Usp13
Mm9::chr5:122952145..122952154,-p3@Atp2a2
Mm9::chr5:122952171..122952185,-p2@Atp2a2
Mm9::chr5:122952636..122952663,-p5@Atp2a2
Mm9::chr6:136499682..136499700,+p@chr6:136499682..136499700
+
Mm9::chr7:36340444..36340532,-p2@Nudt19
Mm9::chr8:86496850..86496927,+p1@Prkaca


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005218intracellular ligand-gated calcium channel activity0.0352514829974452
GO:0014074response to purine0.0352514829974452
GO:0005219ryanodine-sensitive calcium-release channel activity0.0352514829974452
GO:0031000response to caffeine0.0352514829974452
GO:0046873metal ion transmembrane transporter activity0.0352514829974452
GO:0004691cAMP-dependent protein kinase activity0.0471455207305244
GO:0030001metal ion transport0.0471455207305244
GO:0015467G-protein activated inward rectifier potassium channel activity0.0471455207305244
GO:0000209protein polyubiquitination0.0471455207305244
GO:0006816calcium ion transport0.0471455207305244
GO:0004690cyclic nucleotide-dependent protein kinase activity0.0471455207305244
GO:0015278calcium-release channel activity0.0471455207305244
GO:0050811GABA receptor binding0.0471455207305244
GO:0008324cation transmembrane transporter activity0.0471455207305244
GO:0006812cation transport0.0471455207305244
GO:0015674di-, tri-valent inorganic cation transport0.0499393897011789



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)8.42e-1023
neuroblast (sensu Vertebrata)8.42e-1023

Uber Anatomy
Ontology termp-valuen
structure with developmental contribution from neural crest5.26e-2592
regional part of nervous system1.86e-1854
neural tube3.19e-1752
neural rod3.19e-1752
future spinal cord3.19e-1752
neural keel3.19e-1752
central nervous system5.52e-1673
gray matter1.75e-1534
nervous system3.23e-1575
neurectoderm4.41e-1564
neural plate4.41e-1564
presumptive neural plate4.41e-1564
brain1.93e-1447
future brain1.93e-1447
anatomical conduit4.39e-14122
tube6.83e-14114
regional part of brain8.38e-1446
ectoderm-derived structure6.03e-1395
ectoderm6.03e-1395
presumptive ectoderm6.03e-1395
ecto-epithelium6.40e-1373
brain grey matter1.34e-1229
regional part of telencephalon1.34e-1229
telencephalon1.34e-1229
anterior neural tube4.32e-1240
regional part of forebrain1.73e-1139
forebrain1.73e-1139
future forebrain1.73e-1139
pre-chordal neural plate2.22e-1149
primary circulatory organ8.41e-1018
heart8.41e-1018
primitive heart tube8.41e-1018
primary heart field8.41e-1018
anterior lateral plate mesoderm8.41e-1018
heart tube8.41e-1018
heart primordium8.41e-1018
cardiac mesoderm8.41e-1018
cardiogenic plate8.41e-1018
heart rudiment8.41e-1018
occipital lobe5.93e-0910
visual cortex5.93e-0910
neocortex5.93e-0910
cerebral cortex1.27e-0821
cerebral hemisphere1.27e-0821
pallium1.27e-0821
regional part of cerebral cortex1.21e-0717
cardiovascular system1.82e-0723
circulatory system1.82e-0723


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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