MCL coexpression mm9:224: Difference between revisions
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{{MCL_coexpression_mm9| | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0782957534936247,0.0107058691221207,0.0133648676542322,0.0107102773142426,0.0085192474523713,0.0179220340568983,0.0288400031142167,-0.0032547578772763,-0.006786256575786,-0.00591106043642736,0.000394038325144115,-0.000363792239345172,0.00826252488492552,0.00279425229168849,0.000634074409792321,-0.00296764846831795,-0.00825305706526208,0.00726549947843162,0.010374483382646,0.00673667880155004,0.0580577589115618,-3.99566279120255e-05,0.00545488791135519,0.00485845813288796,0.0033519448170689,0.0164699154712805,0.00558636026860207,0.00316017490616613,0.0105872750591089,0.000837467879540012,0.00958903869290814,-0.00825305706526208,-0.00825305706526208,-0.00825305706526208,0.0184246737502634,0.00618787081064665,0.0121802192132265,0.00659363462056795,0.00865562208074012,0.00441302356825781,0.0107105041603359,-0.00245572749829764,0.0137184590647392,0.0502084401859024,0.0407258979945519,0.0204573666350599,0.00461889495920633,0.0205566419137494,0.036916243047358,0.0412933398287682,0.0416734366838756,0.0815154952301488,0.00200514338554907,-0.00825305706526208,-0.00502646864413468,0.0148896590334203,0.00296961770369238,0.0357236021990467,0.993807995834991,1.07519683008274,0.929178092237792,0.026554368355376,-0.00116844864607775,-0.00411580106617218,-0.00825305706526208,-0.00825305706526208,0.0323238898041709,0.0711164246577871,0.121096728299119,0.131316849242894,0.120703016403083,0.287622943498627,0.300134905938334,0.136991410008099,0.149882888100711,0.130134180383949,0.235300101258601,0.234866597127593,0.276454103705941,0.672197703397238,0.707001287625134,0.605570462204713,0.253224651813719,0.226018941251316,0.226814427412639,0.334071828529666,0.388122426717994,0.464001084105133,0.00870016204127612,0.0145462583020963,0.00308479794452519,-0.00825305706526208,-0.00825305706526208,-0.00344697988526141,0.00847194996060416,-0.00413057947664275,0.0255167092909514,-0.00474815631556547,-0.00568134477517239,0.00443836462719269,0.0600049788216764,0.000940693613826331,0.0058492512628923,0.0383652287095279,0.0118603654808669,0.0109000129526332,0.0103410424633689,0.013301264528972,0.000712229718928615,0.00592774666610231,0.0277186252000629,0.0177614439605451,0.0133800642219734,0.0219489445693697,0.022344591039248,0.00943421128834501,-0.0033333468158306,0.000591400725655521,0.00586087208383059,0.027883958413545,0.00802236530069533,0.00692883046212333,-0.00825305706526208,0.134602484384645,0.142520272459233,0.0123409235514313,-0.00094851890711012,-0.00825305706526208,-0.00439928387550712,0.336896094240877,0.0566337032361317,0.163294563006577,0.0500575442434112,0.0464473852138195,0.218075555369369,0.166917433052131,0.0411040852609022,0.0316004004913799,0.0607129425820378,0.0399605492188886,0.0711829265097535,0.111900898622063,0.136352985328663,0.149736396255173,0.141505961189178,0.143649402280085,0.118103762533254,0.0595525110047556,0.081938854736637,0.0858970622778227,0.0951385043449314,0.0573141184070853,0.064196298544947,0.0661930868529451,0.0655251782184547,0.0339726614030773,-0.00825305706526208,-0.00362932821218036,-0.00546792061590953,0.0107118775479954,0.0213492453047209,0.00070317595572679,0.0184779283023641,0.0106094022081439,0.00113182433258611,-3.16538687355821e-05,-0.00296008863461331,-0.00134175258461569,-0.00486014357681992,-0.00486764898615416,-0.00484371771265271,-0.00521406222643148,0.00318646206374817,-0.00404597239303025,0.057578663451677,0.169554988547903,0.00995507054195828,0.00559173080109601,0.025298389354903,0.0259373542139113,0.0107366893372438,0.0150095584302378,0.00516616776523715,0.00639622032688611,-0.00825305706526208,0.0232388873078494,0.0083071600344625,0.00230773936313075,0.00282551485937114,0.00320313896524489,0.00287854979405855,0.00420106250796169,0.0298795599459191,0.028926641618164,0.0212251359568824,0.0232273386259699,0.0265368821755006,0.0155040238358726,0.0103735390822678,0.0125033534091161,0.0133162388845966,0.00723508170308641,0.00461431559520319,0.0165338330058917,0.00459732804181834,-0.00599441088091378,0.00247654097943401,-0.00344106860055982,-0.00572705111639049,-0.00543732903975521,-0.00177895396422845,-0.00555149895603953,-0.00825305706526208,-0.00825305706526208,-0.00220452858797614,-0.00574523439902523,-0.00457817650048765,-0.00825305706526208,0.0025260171245461,0.0314470321747275,0.0149121038489531,0.0130614657501124,0.006253511210322,0.0123286704885154,0.00755289006117677,0.0159044471809014,0.00347195544537224,0.00450317455583436,0.00706457885222859,0.00420255210409242,0.0066300484523251,0.00266922810824474,0.0134663616390106,0.0157274334045631,0.0107476348719973,0.00945857774202725,0.193745377911562,0.178511136991239,0.0468130671179279,0.039078867284447,0.0145054009424095,0.0192822129755415,0.0161399005822177,0.00760574554159235,0.015742075824085,0.0100655606585979,0.0200968577139879,0.0124482627945622,0.00658425473329493,0.0486163801741194,0.0261239608697319,0.0157839651893159,0.0257482014803937,0.0319012374661057,0.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factor activity;4.87239805828158e-07;20669,18505,16876,140477,13172,246086,54422,16873,13798!GO:0043565;sequence-specific DNA binding;7.50904652949013e-07;18505,16876,140477,13172,246086,54422,16873,13798!GO:0006355;regulation of transcription, DNA-dependent;1.1901999276898e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0044451;nucleoplasm part;1.1901999276898e-06;20669,18505,16876,83766,13172,246086,16873!GO:0006351;transcription, DNA-dependent;1.1901999276898e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0032774;RNA biosynthetic process;1.1901999276898e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0045449;regulation of transcription;1.25222133356989e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0005654;nucleoplasm;1.25222133356989e-06;20669,18505,16876,83766,13172,246086,16873!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.3522715200986e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0006350;transcription;1.40927872813406e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0010468;regulation of gene expression;1.85839274777677e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0031323;regulation of cellular metabolic process;2.67439720531192e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0005667;transcription factor complex;2.71664147626017e-06;20669,18505,246086,16876,13172,16873!GO:0031981;nuclear lumen;2.71664147626017e-06;20669,18505,16876,83766,13172,246086,16873!GO:0019222;regulation of metabolic process;3.21206305699881e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0016070;RNA metabolic process;4.02750325884528e-06;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0043233;organelle lumen;5.3120582662618e-06;20669,18505,16876,83766,13172,246086,16873!GO:0031974;membrane-enclosed lumen;5.3120582662618e-06;20669,18505,16876,83766,13172,246086,16873!GO:0003677;DNA binding;5.89520912770347e-06;20669,18505,16876,140477,13172,246086,54422,16873,18071,13798!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.87222645177476e-06;20669,18505,16876,83766,140477,109593,13172,246086,54422,16873,18071,13798!GO:0010467;gene expression;2.23211148596962e-05;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0043283;biopolymer metabolic process;3.39485775885998e-05;20669,18505,16876,83766,140477,109593,243853,246086,13172,54422,16873,18071,13798!GO:0044428;nuclear part;3.57754438809217e-05;20669,18505,16876,83766,13172,246086,16873!GO:0050789;regulation of biological process;4.70755603433095e-05;20669,18505,16876,140477,109593,140919,13172,246086,54422,16873,18071,13798!GO:0043234;protein complex;0.000111908985509395;20669,18505,16876,83766,13172,246086,16873,13798!GO:0050794;regulation of cellular process;0.000111908985509395;20669,18505,16876,140477,109593,13172,246086,54422,16873,18071,13798!GO:0065007;biological regulation;0.00012949928815094;20669,18505,16876,140477,109593,140919,13172,246086,54422,16873,18071,13798!GO:0003676;nucleic acid binding;0.000191543667322009;20669,18505,16876,140477,13172,246086,54422,16873,18071,13798!GO:0043170;macromolecule metabolic process;0.000592673197893004;20669,18505,16876,83766,140477,109593,243853,246086,13172,54422,16873,18071,13798!GO:0032991;macromolecular complex;0.000618771760972181;20669,18505,16876,83766,13172,246086,16873,13798!GO:0005634;nucleus;0.0010018896344164;20669,18505,16876,83766,140477,13172,246086,54422,16873,18071,13798!GO:0007399;nervous system development;0.00311877579333697;18505,16873,140477,54422,13798!GO:0044238;primary metabolic process;0.00496102477809034;20669,18505,16876,83766,140477,109593,243853,246086,13172,54422,16873,18071,13798!GO:0044237;cellular metabolic process;0.00508543312608764;20669,18505,16876,83766,140477,109593,243853,246086,13172,54422,16873,18071,13798!GO:0043231;intracellular membrane-bound organelle;0.00530114834423677;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,18071,13798!GO:0043227;membrane-bound organelle;0.00530114834423677;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,18071,13798!GO:0007275;multicellular organismal development;0.00615939336069996;18505,16876,13172,16873,140477,54422,18071,13798!GO:0030902;hindbrain development;0.0064693499615585;16873,13798!GO:0007420;brain development;0.0064693499615585;16873,140477,13798!GO:0044446;intracellular organelle part;0.00914043744565135;20669,18505,16876,83766,13172,246086,16873!GO:0044422;organelle part;0.00914043744565135;20669,18505,16876,83766,13172,246086,16873!GO:0007417;central nervous system development;0.0115634810794873;16873,140477,13798!GO:0021915;neural tube development;0.0138961149319929;18505,13798!GO:0030917;midbrain-hindbrain boundary development;0.0197354658683251;13798!GO:0004965;GABA-B receptor activity;0.0197354658683251;54393!GO:0021903;rostrocaudal neural tube patterning;0.0197354658683251;13798!GO:0043229;intracellular organelle;0.0215666072893901;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,18071,13798!GO:0043226;organelle;0.0215666072893901;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,18071,13798!GO:0032502;developmental process;0.028069917852192;18505,16876,13172,16873,140477,54422,18071,13798!GO:0048731;system development;0.0288922135031901;18505,16876,16873,140477,54422,13798!GO:0005313;L-glutamate transmembrane transporter activity;0.0335736911544627;140919!GO:0021937;Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;0.0335736911544627;16873!GO:0015172;acidic amino acid transmembrane transporter activity;0.0335736911544627;140919!GO:0016514;SWI/SNF complex;0.0335736911544627;83766!GO:0001504;neurotransmitter uptake;0.0384381861901399;140919!GO:0044424;intracellular part;0.0423670894296677;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,54393,18071,13798!GO:0021532;neural tube patterning;0.0423670894296677;13798!GO:0021692;cerebellar Purkinje cell layer morphogenesis;0.043797599519862;16873!GO:0021940;positive regulation of granule cell precursor proliferation;0.043797599519862;16873!GO:0021694;cerebellar Purkinje cell layer formation;0.043797599519862;16873!GO:0021936;regulation of granule cell precursor proliferation;0.043797599519862;16873!GO:0021702;cerebellar Purkinje cell differentiation;0.043797599519862;16873!GO:0048513;organ development;0.0448353612621322;18505,16876,16873,140477,13798!GO:0009954;proximal/distal pattern formation;0.0448353612621322;13798!GO:0021930;granule cell precursor proliferation;0.0448353612621322;16873!GO:0021534;cell proliferation in hindbrain;0.0448353612621322;16873!GO:0021924;cell proliferation in the external granule layer;0.0448353612621322;16873!GO:0048856;anatomical structure development;0.0448353612621322;18505,16876,16873,140477,54422,13798!GO:0016564;transcription repressor activity;0.0454041794967971;18505,140477!GO:0030901;midbrain development;0.0454041794967971;13798!GO:0021697;cerebellar cortex formation;0.0454041794967971;16873!GO:0021533;cell differentiation in hindbrain;0.0454041794967971;16873!GO:0032501;multicellular organismal process;0.0454041794967971;18505,16876,140477,140919,13172,54422,16873,18071,13798!GO:0008283;cell proliferation;0.0454041794967971;18505,16876,16873!GO:0016566;specific transcriptional repressor activity;0.047205899167591;18505!GO:0035115;embryonic forelimb morphogenesis;0.047205899167591;13798!GO:0005622;intracellular;0.047205899167591;20669,18505,16876,83766,140477,243853,140919,246086,13172,54422,16873,54393,18071,13798!|ontology_enrichment_celltype=CL:0000117!3.23e-23!23;CL:0000337!3.23e-23!23;CL:0000540!4.05e-14!33;CL:0000047!4.05e-14!33;CL:0000031!4.05e-14!33;CL:0000404!4.05e-14!33;CL:0000393!5.89e-11!39;CL:0000211!5.89e-11!39;CL:0002319!2.32e-09!43;CL:0000221!5.20e-09!44;CL:0000133!5.20e-09!44;CL:0000055!1.73e-07!49|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0000073!5.22e-11!54;UBERON:0002346!7.58e-10!64;UBERON:0003075!7.58e-10!64;UBERON:0007284!7.58e-10!64;UBERON:0001017!1.13e-09!73;UBERON:0001049!2.60e-09!52;UBERON:0005068!2.60e-09!52;UBERON:0006241!2.60e-09!52;UBERON:0007135!2.60e-09!52;UBERON:0001016!3.47e-09!75;UBERON:0002240!9.35e-09!6;UBERON:0005174!9.35e-09!6;UBERON:0001137!9.35e-09!6;UBERON:0002420!1.24e-08!8;UBERON:0007245!1.24e-08!8;UBERON:0010009!1.24e-08!8;UBERON:0010011!1.24e-08!8;UBERON:0000454!1.24e-08!8;UBERON:0004121!2.47e-08!95;UBERON:0000924!2.47e-08!95;UBERON:0006601!2.47e-08!95;UBERON:0001948!3.26e-08!5;UBERON:0002315!3.26e-08!5;UBERON:0003076!4.16e-08!12;UBERON:0003057!4.16e-08!12;UBERON:0010371!1.13e-07!73;UBERON:0002020!2.09e-07!34|tfbs_overrepresentation_for_novel_motifs=0.334203,0.89634,0.533416,0.184237,0.128085,0.199199,2.13566,0.102869,0.222028,0.337168,0.913153,0.289127,2.00733,0.31949,0.054602,0,0.594777,0.96063,0.00960617,0.682411,0.0209942,0.189919,0.318341,0.698529,0.877092,0.355231,0.267563,0.221799,0.185917,0.56829,0.206496,0.276054,0.116565,0.118152,1.09983,0.0499623,0.225878,1.49156,0.535776,0.0188643,0.123465,0.464231,0.34152,0.150649,0.230597,0.173055,0.156727,0.0677314,0.237596,0.0734238,0.194935,0.391414,0.527908,0.384277,0.398303,0.328639,0.647068,0.576361,0.564474,1.11053,1.33354,0.404392,0.057147,0.187777,1.1541,0.613156,0.51212,0.827693,0.258356,0.69152,0.483644,0.0463868,0.215096,0.425631,0.124738,1.44531,0.118032,0.150115,0.249556,0.448606,0.216635,0.621965,0.128113,0.186895,0.333764,0.0142713,1.31408,0.569144,0.159613,0.981395,0.572773,0.337596,0.778619,0.276846,0.0267307,0.674796,0.195348,0.287434,0.474954,0.193095,0.398611,0.275851,0.370402,0.195316,0.567075,0.0581623,0.234223,0.234901,0.745529,0.442482,0.921343,0.371815,0.238327,1.39267,0.578983,0.121437,0.238652,0.419435,1.12617,0.218824,0.430076,0.174742,0.357645,0.456803,0.627117,0.252149,0.648499,0.28043,0.510817,0.0504481,0.35702,1.53572,0.485565,0.106608,0.5981,0.276918,0.038545,0.0588404,0.554766,1.33894,0.950969,0.516174,0.752045,0.774734,0.557152,0.46514,0.479133,1.30006,0.0392346,0.268203,0.086258,0.0915413,1.00201,0.293787,1.15938,0.452379,0.124379,0.0127981,0.0354585,0.151156,1.38342,0.333107,0.703155,0.317802,0.188422,0.335503,0.618764,0.600543,0.09335|tfbs_overrepresentation_jaspar=MA0003.1;0.0959022,MA0004.1;1.11818,MA0006.1;0.496256,MA0007.1;0.68365,MA0009.1;0.295418,MA0014.1;0.0879356,MA0017.1;0.876562,MA0019.1;0.171741,MA0024.1;0.728821,MA0025.1;0.48174,MA0027.1;1.83212,MA0028.1;0.529959,MA0029.1;0.248253,MA0030.1;0.252855,MA0031.1;0.64684,MA0038.1;0.719868,MA0040.1;0.30473,MA0041.1;0.115202,MA0042.1;0.104749,MA0043.1;0.369607,MA0046.1;0.32239,MA0048.1;0.113684,MA0050.1;0.489958,MA0051.1;0.367015,MA0052.1;0.310775,MA0055.1;0.428665,MA0056.1;0,MA0057.1;0.734407,MA0058.1;0.748477,MA0059.1;0.109062,MA0060.1;4.80575,MA0061.1;0.0879165,MA0063.1;0,MA0066.1;0.104478,MA0067.1;0.577859,MA0068.1;0.574709,MA0069.1;0.31103,MA0070.1;0.820264,MA0071.1;0.0627582,MA0072.1;0.297449,MA0073.1;0.36079,MA0074.1;0.0876075,MA0076.1;0.203628,MA0077.1;0.769819,MA0078.1;0.817761,MA0081.1;0.303436,MA0083.1;0.965616,MA0084.1;0.878418,MA0087.1;0.335323,MA0088.1;0.0159621,MA0089.1;0,MA0090.1;0.151401,MA0091.1;0.198301,MA0092.1;0.0386321,MA0093.1;1.17817,MA0095.1;0,MA0098.1;0,MA0100.1;0.281053,MA0101.1;0.518315,MA0103.1;0.925959,MA0105.1;0.683736,MA0106.1;0.136153,MA0107.1;0.183235,MA0108.2;0.185867,MA0109.1;0,MA0111.1;0.0427763,MA0113.1;0.76969,MA0114.1;0.539377,MA0115.1;0.371824,MA0116.1;1.4333,MA0117.1;0.346488,MA0119.1;0.280579,MA0122.1;0.362012,MA0124.1;1.31617,MA0125.1;0.468049,MA0130.1;0,MA0131.1;0.168986,MA0132.1;0,MA0133.1;0,MA0135.1;0.398744,MA0136.1;0.0967843,MA0139.1;0.327068,MA0140.1;0.280914,MA0141.1;0.0197122,MA0142.1;0.218511,MA0143.1;0.129679,MA0144.1;0.0296755,MA0145.1;0.236529,MA0146.1;0.0960995,MA0147.1;0.382092,MA0148.1;0.0547891,MA0149.1;0.0292146,MA0062.2;0.119481,MA0035.2;0.28663,MA0039.2;0.090945,MA0138.2;0.954498,MA0002.2;0.198589,MA0137.2;0.019155,MA0104.2;0.23117,MA0047.2;0.109541,MA0112.2;0.0457301,MA0065.2;0.350066,MA0150.1;0.0443275,MA0151.1;0,MA0152.1;0.718358,MA0153.1;0.412245,MA0154.1;0.0234653,MA0155.1;0.994678,MA0156.1;0.0791428,MA0157.1;0.573924,MA0158.1;0,MA0159.1;0.234667,MA0160.1;0.0558568,MA0161.1;0,MA0162.1;0.058162,MA0163.1;0.0739582,MA0164.1;0.0969555,MA0080.2;0.184454,MA0018.2;0.333023,MA0099.2;0.938999,MA0079.2;0.079673,MA0102.2;0.928086,MA0258.1;0.0735493,MA0259.1;0.81249,MA0442.1;0}} |
Latest revision as of 14:55, 17 September 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0003700 | transcription factor activity | 4.87239805828158e-07 |
GO:0043565 | sequence-specific DNA binding | 7.50904652949013e-07 |
GO:0006355 | regulation of transcription, DNA-dependent | 1.1901999276898e-06 |
GO:0044451 | nucleoplasm part | 1.1901999276898e-06 |
GO:0006351 | transcription, DNA-dependent | 1.1901999276898e-06 |
GO:0032774 | RNA biosynthetic process | 1.1901999276898e-06 |
GO:0045449 | regulation of transcription | 1.25222133356989e-06 |
GO:0005654 | nucleoplasm | 1.25222133356989e-06 |
GO:0019219 | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 1.3522715200986e-06 |
GO:0006350 | transcription | 1.40927872813406e-06 |
GO:0010468 | regulation of gene expression | 1.85839274777677e-06 |
GO:0031323 | regulation of cellular metabolic process | 2.67439720531192e-06 |
GO:0005667 | transcription factor complex | 2.71664147626017e-06 |
GO:0031981 | nuclear lumen | 2.71664147626017e-06 |
GO:0019222 | regulation of metabolic process | 3.21206305699881e-06 |
GO:0016070 | RNA metabolic process | 4.02750325884528e-06 |
GO:0043233 | organelle lumen | 5.3120582662618e-06 |
GO:0031974 | membrane-enclosed lumen | 5.3120582662618e-06 |
GO:0003677 | DNA binding | 5.89520912770347e-06 |
GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 6.87222645177476e-06 |
GO:0010467 | gene expression | 2.23211148596962e-05 |
GO:0043283 | biopolymer metabolic process | 3.39485775885998e-05 |
GO:0044428 | nuclear part | 3.57754438809217e-05 |
GO:0050789 | regulation of biological process | 4.70755603433095e-05 |
GO:0043234 | protein complex | 0.000111908985509395 |
GO:0050794 | regulation of cellular process | 0.000111908985509395 |
GO:0065007 | biological regulation | 0.00012949928815094 |
GO:0003676 | nucleic acid binding | 0.000191543667322009 |
GO:0043170 | macromolecule metabolic process | 0.000592673197893004 |
GO:0032991 | macromolecular complex | 0.000618771760972181 |
GO:0005634 | nucleus | 0.0010018896344164 |
GO:0007399 | nervous system development | 0.00311877579333697 |
GO:0044238 | primary metabolic process | 0.00496102477809034 |
GO:0044237 | cellular metabolic process | 0.00508543312608764 |
GO:0043231 | intracellular membrane-bound organelle | 0.00530114834423677 |
GO:0043227 | membrane-bound organelle | 0.00530114834423677 |
GO:0007275 | multicellular organismal development | 0.00615939336069996 |
GO:0030902 | hindbrain development | 0.0064693499615585 |
GO:0007420 | brain development | 0.0064693499615585 |
GO:0044446 | intracellular organelle part | 0.00914043744565135 |
GO:0044422 | organelle part | 0.00914043744565135 |
GO:0007417 | central nervous system development | 0.0115634810794873 |
GO:0021915 | neural tube development | 0.0138961149319929 |
GO:0030917 | midbrain-hindbrain boundary development | 0.0197354658683251 |
GO:0004965 | GABA-B receptor activity | 0.0197354658683251 |
GO:0021903 | rostrocaudal neural tube patterning | 0.0197354658683251 |
GO:0043229 | intracellular organelle | 0.0215666072893901 |
GO:0043226 | organelle | 0.0215666072893901 |
GO:0032502 | developmental process | 0.028069917852192 |
GO:0048731 | system development | 0.0288922135031901 |
GO:0005313 | L-glutamate transmembrane transporter activity | 0.0335736911544627 |
GO:0021937 | Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation | 0.0335736911544627 |
GO:0015172 | acidic amino acid transmembrane transporter activity | 0.0335736911544627 |
GO:0016514 | SWI/SNF complex | 0.0335736911544627 |
GO:0001504 | neurotransmitter uptake | 0.0384381861901399 |
GO:0044424 | intracellular part | 0.0423670894296677 |
GO:0021532 | neural tube patterning | 0.0423670894296677 |
GO:0021692 | cerebellar Purkinje cell layer morphogenesis | 0.043797599519862 |
GO:0021940 | positive regulation of granule cell precursor proliferation | 0.043797599519862 |
GO:0021694 | cerebellar Purkinje cell layer formation | 0.043797599519862 |
GO:0021936 | regulation of granule cell precursor proliferation | 0.043797599519862 |
GO:0021702 | cerebellar Purkinje cell differentiation | 0.043797599519862 |
GO:0048513 | organ development | 0.0448353612621322 |
GO:0009954 | proximal/distal pattern formation | 0.0448353612621322 |
GO:0021930 | granule cell precursor proliferation | 0.0448353612621322 |
GO:0021534 | cell proliferation in hindbrain | 0.0448353612621322 |
GO:0021924 | cell proliferation in the external granule layer | 0.0448353612621322 |
GO:0048856 | anatomical structure development | 0.0448353612621322 |
GO:0016564 | transcription repressor activity | 0.0454041794967971 |
GO:0030901 | midbrain development | 0.0454041794967971 |
GO:0021697 | cerebellar cortex formation | 0.0454041794967971 |
GO:0021533 | cell differentiation in hindbrain | 0.0454041794967971 |
GO:0032501 | multicellular organismal process | 0.0454041794967971 |
GO:0008283 | cell proliferation | 0.0454041794967971 |
GO:0016566 | specific transcriptional repressor activity | 0.047205899167591 |
GO:0035115 | embryonic forelimb morphogenesis | 0.047205899167591 |
GO:0005622 | intracellular | 0.047205899167591 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
CNS neuron (sensu Vertebrata) | 3.23e-23 | 23 |
neuroblast (sensu Vertebrata) | 3.23e-23 | 23 |
neuron | 4.05e-14 | 33 |
neuronal stem cell | 4.05e-14 | 33 |
neuroblast | 4.05e-14 | 33 |
electrically signaling cell | 4.05e-14 | 33 |
electrically responsive cell | 5.89e-11 | 39 |
electrically active cell | 5.89e-11 | 39 |
neural cell | 2.32e-09 | 43 |
ectodermal cell | 5.20e-09 | 44 |
neurectodermal cell | 5.20e-09 | 44 |
non-terminally differentiated cell | 1.73e-07 | 49 |
Ontology term | p-value | n |
---|---|---|
regional part of nervous system | 5.22e-11 | 54 |
neurectoderm | 7.58e-10 | 64 |
neural plate | 7.58e-10 | 64 |
presumptive neural plate | 7.58e-10 | 64 |
central nervous system | 1.13e-09 | 73 |
neural tube | 2.60e-09 | 52 |
neural rod | 2.60e-09 | 52 |
future spinal cord | 2.60e-09 | 52 |
neural keel | 2.60e-09 | 52 |
nervous system | 3.47e-09 | 75 |
spinal cord | 9.35e-09 | 6 |
dorsal region element | 9.35e-09 | 6 |
dorsum | 9.35e-09 | 6 |
basal ganglion | 1.24e-08 | 8 |
nuclear complex of neuraxis | 1.24e-08 | 8 |
aggregate regional part of brain | 1.24e-08 | 8 |
collection of basal ganglia | 1.24e-08 | 8 |
cerebral subcortex | 1.24e-08 | 8 |
ectoderm-derived structure | 2.47e-08 | 95 |
ectoderm | 2.47e-08 | 95 |
presumptive ectoderm | 2.47e-08 | 95 |
regional part of spinal cord | 3.26e-08 | 5 |
gray matter of spinal cord | 3.26e-08 | 5 |
posterior neural tube | 4.16e-08 | 12 |
chordal neural plate | 4.16e-08 | 12 |
ecto-epithelium | 1.13e-07 | 73 |
gray matter | 2.09e-07 | 34 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.0959022 |
MA0004.1 | 1.11818 |
MA0006.1 | 0.496256 |
MA0007.1 | 0.68365 |
MA0009.1 | 0.295418 |
MA0014.1 | 0.0879356 |
MA0017.1 | 0.876562 |
MA0019.1 | 0.171741 |
MA0024.1 | 0.728821 |
MA0025.1 | 0.48174 |
MA0027.1 | 1.83212 |
MA0028.1 | 0.529959 |
MA0029.1 | 0.248253 |
MA0030.1 | 0.252855 |
MA0031.1 | 0.64684 |
MA0038.1 | 0.719868 |
MA0040.1 | 0.30473 |
MA0041.1 | 0.115202 |
MA0042.1 | 0.104749 |
MA0043.1 | 0.369607 |
MA0046.1 | 0.32239 |
MA0048.1 | 0.113684 |
MA0050.1 | 0.489958 |
MA0051.1 | 0.367015 |
MA0052.1 | 0.310775 |
MA0055.1 | 0.428665 |
MA0056.1 | 0 |
MA0057.1 | 0.734407 |
MA0058.1 | 0.748477 |
MA0059.1 | 0.109062 |
MA0060.1 | 4.80575 |
MA0061.1 | 0.0879165 |
MA0063.1 | 0 |
MA0066.1 | 0.104478 |
MA0067.1 | 0.577859 |
MA0068.1 | 0.574709 |
MA0069.1 | 0.31103 |
MA0070.1 | 0.820264 |
MA0071.1 | 0.0627582 |
MA0072.1 | 0.297449 |
MA0073.1 | 0.36079 |
MA0074.1 | 0.0876075 |
MA0076.1 | 0.203628 |
MA0077.1 | 0.769819 |
MA0078.1 | 0.817761 |
MA0081.1 | 0.303436 |
MA0083.1 | 0.965616 |
MA0084.1 | 0.878418 |
MA0087.1 | 0.335323 |
MA0088.1 | 0.0159621 |
MA0089.1 | 0 |
MA0090.1 | 0.151401 |
MA0091.1 | 0.198301 |
MA0092.1 | 0.0386321 |
MA0093.1 | 1.17817 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.281053 |
MA0101.1 | 0.518315 |
MA0103.1 | 0.925959 |
MA0105.1 | 0.683736 |
MA0106.1 | 0.136153 |
MA0107.1 | 0.183235 |
MA0108.2 | 0.185867 |
MA0109.1 | 0 |
MA0111.1 | 0.0427763 |
MA0113.1 | 0.76969 |
MA0114.1 | 0.539377 |
MA0115.1 | 0.371824 |
MA0116.1 | 1.4333 |
MA0117.1 | 0.346488 |
MA0119.1 | 0.280579 |
MA0122.1 | 0.362012 |
MA0124.1 | 1.31617 |
MA0125.1 | 0.468049 |
MA0130.1 | 0 |
MA0131.1 | 0.168986 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.398744 |
MA0136.1 | 0.0967843 |
MA0139.1 | 0.327068 |
MA0140.1 | 0.280914 |
MA0141.1 | 0.0197122 |
MA0142.1 | 0.218511 |
MA0143.1 | 0.129679 |
MA0144.1 | 0.0296755 |
MA0145.1 | 0.236529 |
MA0146.1 | 0.0960995 |
MA0147.1 | 0.382092 |
MA0148.1 | 0.0547891 |
MA0149.1 | 0.0292146 |
MA0062.2 | 0.119481 |
MA0035.2 | 0.28663 |
MA0039.2 | 0.090945 |
MA0138.2 | 0.954498 |
MA0002.2 | 0.198589 |
MA0137.2 | 0.019155 |
MA0104.2 | 0.23117 |
MA0047.2 | 0.109541 |
MA0112.2 | 0.0457301 |
MA0065.2 | 0.350066 |
MA0150.1 | 0.0443275 |
MA0151.1 | 0 |
MA0152.1 | 0.718358 |
MA0153.1 | 0.412245 |
MA0154.1 | 0.0234653 |
MA0155.1 | 0.994678 |
MA0156.1 | 0.0791428 |
MA0157.1 | 0.573924 |
MA0158.1 | 0 |
MA0159.1 | 0.234667 |
MA0160.1 | 0.0558568 |
MA0161.1 | 0 |
MA0162.1 | 0.058162 |
MA0163.1 | 0.0739582 |
MA0164.1 | 0.0969555 |
MA0080.2 | 0.184454 |
MA0018.2 | 0.333023 |
MA0099.2 | 0.938999 |
MA0079.2 | 0.079673 |
MA0102.2 | 0.928086 |
MA0258.1 | 0.0735493 |
MA0259.1 | 0.81249 |
MA0442.1 | 0 |