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MCL coexpression mm9:1191: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0017000;antibiotic biosynthetic process;0.0153365824918586;!GO:0016999;antibiotic metabolic process;0.0153365824918586;!GO:0017144;drug metabolic process;0.0153365824918586;!GO:0046658;anchored to plasma membrane;0.0202376340836703;80883!GO:0031225;anchored to membrane;0.0202376340836703;80883!}}
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biosynthetic process;0.0153365824918586;!GO:0016999;antibiotic metabolic process;0.0153365824918586;!GO:0017144;drug metabolic process;0.0153365824918586;!GO:0046658;anchored to plasma membrane;0.0202376340836703;80883!GO:0031225;anchored to membrane;0.0202376340836703;80883!|ontology_enrichment_celltype=CL:0000117!1.77e-15!23;CL:0000337!1.77e-15!23;CL:0000540!2.07e-15!33;CL:0000047!2.07e-15!33;CL:0000031!2.07e-15!33;CL:0000404!2.07e-15!33;CL:0000221!3.76e-15!44;CL:0000133!3.76e-15!44;CL:0002319!1.94e-14!43;CL:0000393!1.41e-11!39;CL:0000211!1.41e-11!39;CL:0000055!2.33e-11!49|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0001017!4.82e-29!73;UBERON:0001016!8.76e-29!75;UBERON:0002346!6.37e-28!64;UBERON:0003075!6.37e-28!64;UBERON:0007284!6.37e-28!64;UBERON:0004121!3.62e-27!95;UBERON:0000924!3.62e-27!95;UBERON:0006601!3.62e-27!95;UBERON:0000073!3.46e-25!54;UBERON:0010371!9.45e-25!73;UBERON:0001049!5.92e-23!52;UBERON:0005068!5.92e-23!52;UBERON:0006241!5.92e-23!52;UBERON:0007135!5.92e-23!52;UBERON:0000955!8.62e-19!47;UBERON:0006238!8.62e-19!47;UBERON:0002616!7.89e-18!46;UBERON:0002020!2.25e-17!34;UBERON:0003056!2.31e-17!49;UBERON:0010314!1.35e-16!92;UBERON:0003080!1.13e-14!40;UBERON:0002780!7.92e-14!39;UBERON:0001890!7.92e-14!39;UBERON:0006240!7.92e-14!39;UBERON:0003528!3.42e-13!29;UBERON:0002791!3.42e-13!29;UBERON:0001893!3.42e-13!29;UBERON:0003076!2.25e-09!12;UBERON:0003057!2.25e-09!12;UBERON:0002420!5.05e-08!8;UBERON:0007245!5.05e-08!8;UBERON:0010009!5.05e-08!8;UBERON:0010011!5.05e-08!8;UBERON:0000454!5.05e-08!8;UBERON:0000956!2.82e-07!21;UBERON:0001869!2.82e-07!21;UBERON:0000203!2.82e-07!21|tfbs_overrepresentation_for_novel_motifs=1.95401,0.660133,1.05921,0.480627,0.299217,0.495263,0.587291,0.206208,0.616096,0.219671,0.542749,0.575086,0.206435,0.599731,0.315771,0,0.795315,0.291368,0.19222,0.112498,0.374752,0.08187,0.598814,0.29769,0.419327,0.62766,0.184473,0.516511,0.344372,0.446946,0.50223,0.897561,0.289148,0.498917,0.316253,0.0235321,0.279977,1.40099,0.258564,0.230656,0.295233,0.507468,0.0742755,0.317766,0.277561,0.469348,0.714592,0.532496,0.0609361,0.347313,0.777641,0.654933,0.431711,1.04034,1.0579,0.606984,0.356236,0.56214,0.176152,0.604914,2.03558,0.664501,0.226529,0.766235,0.618279,0.807219,1.19497,1.54543,0.872612,1.39786,0.392734,0.21183,0.293368,1.09164,1.55661,0.159969,0.963958,1.67636,0.859987,0.378988,1.14907,0.812889,0.663039,0.580284,0.975495,0.960306,0.042613,0.447265,0.719558,1.70793,1.26498,0.980512,0.910485,0.305079,0.254625,0.668513,0.203879,0.913319,0.71485,0.127063,0.280055,0.897279,1.02279,0.778243,1.82972,0.507021,0.837607,0.528416,0.383871,1.74385,0.430942,1.02459,0.380122,0.547992,1.27206,0.796976,0.735764,0.484437,0.796633,0.276329,1.09707,1.76329,0.629509,0.702145,1.32639,0.863723,0.595563,0.903645,1.19345,0.308038,1.00568,0.473246,1.16374,0.620831,1.29374,0.275843,0.446555,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,0.448938,0.300961,0.452587,0.545091,1.04192,0.681896,0.619892,1.12411,0.655955,0.874089,0.435579,0.446272,1.25393,0.974632,0.864173,0.428662,0.767269,0.612377,0.278874,0.573477,0.227149|tfbs_overrepresentation_jaspar=MA0003.1;3.14246,MA0004.1;0.481116,MA0006.1;0.311391,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;0.694761,MA0017.1;0.337808,MA0019.1;0.740036,MA0024.1;0.880057,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;0.321735,MA0029.1;1.99617,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;0.128106,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.648475,MA0056.1;0,MA0057.1;1.23731,MA0058.1;1.00014,MA0059.1;1.02718,MA0060.1;0.232592,MA0061.1;1.33382,MA0063.1;0,MA0066.1;2.54082,MA0067.1;1.27078,MA0068.1;0.385183,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;0.519509,MA0072.1;0.927016,MA0073.1;0.845602,MA0074.1;0.580087,MA0076.1;0.356883,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;0.420276,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;0.598004,MA0089.1;0,MA0090.1;0.446539,MA0091.1;0.494398,MA0092.1;0.446857,MA0093.1;0.879104,MA0095.1;0,MA0098.1;0,MA0100.1;1.39455,MA0101.1;0.406019,MA0103.1;0.348572,MA0105.1;0.488671,MA0106.1;0.677988,MA0107.1;0.342432,MA0108.2;0.763162,MA0109.1;0,MA0111.1;0.460823,MA0113.1;0.649407,MA0114.1;0.259463,MA0115.1;1.0246,MA0116.1;1.51389,MA0117.1;0.992087,MA0119.1;0.40661,MA0122.1;1.01209,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;0.735438,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.202522,MA0140.1;0.568252,MA0141.1;0.368264,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.262477,MA0145.1;0.304732,MA0146.1;0.0256827,MA0147.1;1.38091,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;0.500692,MA0035.2;1.40435,MA0039.2;0.219063,MA0138.2;0.727395,MA0002.2;1.75516,MA0137.2;0.365364,MA0104.2;0.624968,MA0047.2;0.626803,MA0112.2;0.631649,MA0065.2;0.633155,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.397336,MA0155.1;2.2767,MA0156.1;0.356017,MA0157.1;0.781683,MA0158.1;0,MA0159.1;0.284457,MA0160.1;0.50056,MA0161.1;0,MA0162.1;1.71182,MA0163.1;1.20194,MA0164.1;0.600609,MA0080.2;0.343316,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;2.51924,MA0102.2;1.65195,MA0258.1;1.97513,MA0259.1;0.26402,MA0442.1;0}}

Latest revision as of 16:32, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr2:90725578..90725583,+p13@C1qtnf4
Mm9::chr3:109945914..109945928,-p2@Ntng1
Mm9::chr3:109946431..109946443,-p8@Ntng1
Mm9::chr3:109946598..109946609,-p5@Ntng1
Mm9::chr3:109946616..109946633,-p3@Ntng1
Mm9::chr3:109946704..109946760,-p1@Ntng1
Mm9::chr8:121970822..121970847,+p2@Necab2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0017000antibiotic biosynthetic process0.0153365824918586
GO:0016999antibiotic metabolic process0.0153365824918586
GO:0017144drug metabolic process0.0153365824918586
GO:0046658anchored to plasma membrane0.0202376340836703
GO:0031225anchored to membrane0.0202376340836703



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
central nervous system4.82e-2973
nervous system8.76e-2975
neurectoderm6.37e-2864
neural plate6.37e-2864
presumptive neural plate6.37e-2864
ectoderm-derived structure3.62e-2795
ectoderm3.62e-2795
presumptive ectoderm3.62e-2795
regional part of nervous system3.46e-2554
ecto-epithelium9.45e-2573
neural tube5.92e-2352
neural rod5.92e-2352
future spinal cord5.92e-2352
neural keel5.92e-2352
brain8.62e-1947
future brain8.62e-1947
regional part of brain7.89e-1846
gray matter2.25e-1734
pre-chordal neural plate2.31e-1749
structure with developmental contribution from neural crest1.35e-1692
anterior neural tube1.13e-1440
regional part of forebrain7.92e-1439
forebrain7.92e-1439
future forebrain7.92e-1439
brain grey matter3.42e-1329
regional part of telencephalon3.42e-1329
telencephalon3.42e-1329
posterior neural tube2.25e-0912
chordal neural plate2.25e-0912
basal ganglion5.05e-088
nuclear complex of neuraxis5.05e-088
aggregate regional part of brain5.05e-088
collection of basal ganglia5.05e-088
cerebral subcortex5.05e-088
cerebral cortex2.82e-0721
cerebral hemisphere2.82e-0721
pallium2.82e-0721


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.13.14246
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.694761
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.11.99617
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.648475
MA0056.10
MA0057.11.23731
MA0058.11.00014
MA0059.11.02718
MA0060.10.232592
MA0061.11.33382
MA0063.10
MA0066.12.54082
MA0067.11.27078
MA0068.10.385183
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.845602
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.598004
MA0089.10
MA0090.10.446539
MA0091.10.494398
MA0092.10.446857
MA0093.10.879104
MA0095.10
MA0098.10
MA0100.11.39455
MA0101.10.406019
MA0103.10.348572
MA0105.10.488671
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.11.51389
MA0117.10.992087
MA0119.10.40661
MA0122.11.01209
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.10.568252
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.304732
MA0146.10.0256827
MA0147.11.38091
MA0148.10.49752
MA0149.10.411562
MA0062.20.500692
MA0035.21.40435
MA0039.20.219063
MA0138.20.727395
MA0002.21.75516
MA0137.20.365364
MA0104.20.624968
MA0047.20.626803
MA0112.20.631649
MA0065.20.633155
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.397336
MA0155.12.2767
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.11.71182
MA0163.11.20194
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.22.51924
MA0102.21.65195
MA0258.11.97513
MA0259.10.26402
MA0442.10
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