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MCL coexpression mm9:2833: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0215045709288587,0.12648966102998,0,0.34688483554342,0.37155364417352,0.0224659834789971,0.0303929369543796,0.891335348722256,0.496365711089727,0.38542892878683,0.221661051197289,0.160244974648471,1.19692498975305,0.972231547285088,0.0416219695316507,0.670940106807247,0.517209034931429,1.29156900500511,1.29158372612433,1.33770355413076,0.0227393328203088,0,0.163300673105039,0.262242587632923,0.226675377344028,0.110709355488891,0.0518557986393603,0.0282482281944011,0.096686896638192,0.100929924601095,0.0289918065944652,0,0,0,0,0.0585719493020967,0,0.205795071490867,0.456806800654504,0.300187761171396,0.265512528766986,0.190654268992297,0.178328007504615,0,0.0139786585896141,0,0,0.0285520860180518,0.0527243868018057,0.0832877532641737,0,0,1.26122332473511,1.17666844746013,1.15127475592753,0,0.036473692999102,0,0.0266729310181638,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0205844358967264,0,0,0,0.324452626549135,0.206851006512731,0.410090638730602,0.331353802319401,0,0.0624790033400087,0.0724750304454203,0,0.0645397373349033,0,0.0834211128761177,0.207060705919805,0,0.290062895727317,0.183330008266007,0,0.0724484144753017,0.0653838558695874,0.059229270497327,0.0156522902305435,0.116548728194479,0,0,0,0,0,0,0,0.0581546446587617,0.0195511658563466,0,0,0.052956596168637,0,0,0,0,0,0.210528055497326,0.291271164043018,0.231833709917009,0,0.0545362476847357,0,0,0,0,0.0217654300465033,0,0.032165912785898,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0270896151765207,0,0.218093058354787,0.355436936901653,0,0,0.0305000873390897,0,0,0,0,0.0302662962845869,0,0,0.022053937674874,0,0.0217525199289503,0.0197534664523989,0,0.0182307002463379,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0257849511336695,0,0,0,0,0,0,0,0,0.0098129670432154,0.0088766307709278,0,0.0395315080974153,0.0168444410470322,0,0,0,0,0,0,0,0.0366044643315893,0.0217522219232226,0,0,0,0,0.059194006936492,0,0,0.0455213533034023,0,0,0,0.030519339351902,0,0.0309119845936582,0.0476994355509397,0.0211905676183425,0,0.0214179370325552,0.0439346528837465,0.0429472425151403,0.090450769599442,0.744035327230787,0.672577327994146,0,0,0,0.0160451566633019,0,0,0,0,0,0,0,0,0,0,0,0,0.0192144393809059,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0239681640494532,0,0,0,0,0.0220525914918694,0.038477471376504,0.0305171655333305,0,0,0,0.0216686375930551,0,0,0,0.0370293221228937,0,0.0228363351212467,0,0,0.0249837052527249,0.0682960779231233,0.0298244961268902,0.111774754841602,0.11471987255138,0.199087976683909,0,0,0,0.0148472845964615,0,0,0.0183146507189827,0.0114964888195113,0.0336584528774773,0.0333683477944273,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0353653414676601,0,0.0262345833426259,0.0328625360911347,0,0,0.0212638229928587,0.0139062504973587,0.0134626204920181,0.0254768643902302,0.0320035396722468,0,0.0290220712522073,0,0,0.0255698190552108,0.0461393176027847,0,0,0,0,0,0,0.125210565343104,0,0,0,0,0,0,0.0142951371858648,0,0,0,0,0,0.0532385261925647,0.0271199773786347,0,0,0.0593671070790283,0,0.0129583282823702,0,0,0,0,0,0.0499537055884833,0.0198795765065911,0,0.0236506641178082,0,0.0392912409442346,0,0,0,0,0,0.0644808278156693,0.0162294701681744,0,0,0,0.0255354818037453,0,0.030430363092515,0,0.0253389627196635,0,0|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,1.12276342337695,0.429665842895536,0.458262488237196,0.180026585552633,0.192680364412534,1.40330078721041,1.2303961294884,0,0.720323114459876,0.491177518744176,1.41629496679143,1.48205120018642,1.52734633371993,0,0,0,0.255263364065407,0.227431058621176,0,0,0,0,0,0,0,0,0,0,0,0,0.264124112013994,0.615459892883158,0.410029642905161,0.200913802025349,0,0,0,0,0,0,0,0,0,0,0,1.37075115930029,1.32858630240039,1.36515447488962,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0889077662030289,0,0.110544086345426,0.269611904680974,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0980757838043811,0,0,0.100004302423367,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.203869002627234,0.3423842760398,0.213611016799815,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.180325425270187,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0659019793256198,0,0,1.11605299084618,0.681904819504779,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.055643654597214,0,0.0681778550615498,0.056886356216389,0.15063362961962,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0530480122014902,0,0,0.0492938041367021,0,0,0.031895734489288,0,0,0,0.0480053095083702,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0589368614163519,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0|gostat_on_MCL_coexpression=|ontology_enrichment_celltype=CL:0000988!3.30e-28!32;CL:0002032!3.30e-28!32;CL:0000037!3.30e-28!32;CL:0000566!3.30e-28!32;CL:0000837!3.30e-28!32;CL:0002031!1.91e-24!25;CL:0002320!6.56e-22!46;CL:0000134!6.56e-22!46;CL:0000791!4.25e-20!9;CL:0000789!4.25e-20!9;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|ontology_enrichment_disease=DOID:0060100!1.57e-07!3;DOID:4045!1.57e-07!3
|ontology_enrichment_uberon=UBERON:0002384!6.56e-22!46;UBERON:0002193!2.65e-17!48;UBERON:0002405!2.65e-17!48;UBERON:0002390!1.67e-13!45;UBERON:0003061!1.67e-13!45;UBERON:0002371!1.62e-08!16;UBERON:0002370!2.44e-07!23;UBERON:0000974!2.44e-07!23;UBERON:0004807!2.44e-07!23;UBERON:0005058!2.44e-07!23;UBERON:0003351!2.44e-07!23;UBERON:0009113!2.44e-07!23;UBERON:0003295!2.44e-07!23;UBERON:0009722!2.44e-07!23;UBERON:0005562!2.44e-07!23;UBERON:0007690!2.44e-07!23;UBERON:0000072!2.89e-07!27;UBERON:0002465!5.17e-07!3;UBERON:0006562!5.91e-07!24;UBERON:0003408!5.91e-07!24;UBERON:0001557!5.91e-07!24;UBERON:0001042!5.91e-07!24;UBERON:0008814!5.91e-07!24;UBERON:0009145!5.91e-07!24;UBERON:0002204!8.19e-07!32
|tfbs_overrepresentation_for_novel_motifs=0.752782,0.193418,0.722405,0.801166,0.587814,0.81763,0.919454,0.467321,0.479531,0.235304,0.870507,0.906098,0.467629,0.933025,0.608226,0,1.14208,0.578045,0.448066,0.328717,0.679146,0.756749,0.932027,0.585919,0.731217,0.963352,0.437236,0.841386,0.64294,0.380786,0.825437,1.24901,0.575271,0.411696,0.608816,0.144706,0.563758,0.902078,0.536514,0.50014,0.582863,0.831295,0.261619,0.610669,0.156582,0.788421,1.05665,0.859154,0.235354,0.646474,1.12346,0.99279,0.371606,1.3966,1.41464,0.940919,0.657156,0.891887,0.425455,0.938668,1.22795,1.00308,0.494668,1.11142,0.953187,1.15459,1.55483,1.90983,1.22303,1.7608,0.700291,0.474956,0.284975,1.44925,0.416814,0.402065,0.411601,1.04436,1.20986,0.684144,1.19917,1.16055,1.00151,0.459035,1.32978,0.181575,4.94084,0.380977,1.06194,2.07346,1.62608,1.33496,1.26245,0.595071,0.531443,0.509215,0.464141,1.26539,1.05692,0.352122,0.563856,1.24872,1.37854,1.12409,1.12297,0.830796,1.18646,0.854628,0.689894,0.681267,0.744607,1.38039,0.685481,0.876299,1.63327,1.42046,0.212464,0.805461,1.14346,0.559153,1.45481,1.08896,0.965352,1.04338,1.68841,1.21376,0.928483,1.25534,1.55328,1.45847,1.36093,0.792832,1.52297,0.955954,1.65529,0.273451,0.762499,0.832891,1.60513,2.44352,2.04137,1.55966,0.978551,1.26,1.11604,0.831808,1.06002,2.40374,0.765221,0.589976,0.38417,0.260379,1.39822,0.516739,0.954936,1.48249,0.993889,0.622823,0.749933,0.762177,1.61484,1.32889,1.21423,0.741984,1.11251,0.94678,0.562367,0.904334,0.135528
|tfbs_overrepresentation_jaspar=MA0003.1;0.0699972,MA0004.1;0.801718,MA0006.1;0.60285,MA0007.1;0.784593,MA0009.1;1.27673,MA0014.1;0.133574,MA0017.1;0.635031,MA0019.1;1.08369,MA0024.1;1.23079,MA0025.1;3.33329,MA0027.1;2.9431,MA0028.1;0.61552,MA0029.1;1.20789,MA0030.1;1.21482,MA0031.1;1.17722,MA0038.1;0.963265,MA0040.1;1.28983,MA0041.1;0.714279,MA0042.1;0.69885,MA0043.1;1.3775,MA0046.1;1.31428,MA0048.1;0.932001,MA0050.1;0.845669,MA0051.1;0.973068,MA0052.1;1.29825,MA0055.1;0.190475,MA0056.1;0,MA0057.1;0.337566,MA0058.1;0.690848,MA0059.1;0.705317,MA0060.1;0.502699,MA0061.1;0.5406,MA0063.1;0,MA0066.1;0.951196,MA0067.1;1.63197,MA0068.1;0.343188,MA0069.1;1.29861,MA0070.1;1.28847,MA0071.1;0.844726,MA0072.1;1.2796,MA0073.1;2.57794,MA0074.1;0.911576,MA0076.1;0.657929,MA0077.1;1.2569,MA0078.1;1.0091,MA0081.1;0.732313,MA0083.1;1.37668,MA0084.1;1.96428,MA0087.1;1.33189,MA0088.1;0.27999,MA0089.1;0,MA0090.1;0.762482,MA0091.1;0.816659,MA0092.1;0.762845,MA0093.1;0.62555,MA0095.1;0,MA0098.1;0,MA0100.1;0.89873,MA0101.1;0.71579,MA0103.1;0.647985,MA0105.1;0.405648,MA0106.1;1.01755,MA0107.1;0.640607,MA0108.2;1.10817,MA0109.1;0,MA0111.1;0.778753,MA0113.1;0.986839,MA0114.1;0.537669,MA0115.1;1.38041,MA0116.1;0.602598,MA0117.1;1.34691,MA0119.1;0.716476,MA0122.1;1.36752,MA0124.1;1.57762,MA0125.1;1.5017,MA0130.1;0,MA0131.1;1.07881,MA0132.1;0,MA0133.1;0,MA0135.1;1.4152,MA0136.1;0.933582,MA0139.1;0.462282,MA0140.1;0.898603,MA0141.1;0.671467,MA0142.1;2.61449,MA0143.1;1.00467,MA0144.1;0.541532,MA0145.1;0.292366,MA0146.1;0.151124,MA0147.1;0.556853,MA0148.1;0.820161,MA0149.1;0.722227,MA0062.2;0.412742,MA0035.2;0.903829,MA0039.2;0.0481552,MA0138.2;1.07027,MA0002.2;0.466067,MA0137.2;0.668025,MA0104.2;0.48458,MA0047.2;0.962424,MA0112.2;0.29236,MA0065.2;0.292912,MA0150.1;1.84475,MA0151.1;0,MA0152.1;0.962542,MA0153.1;1.43238,MA0154.1;0.925147,MA0155.1;0.312898,MA0156.1;1.58027,MA0157.1;1.12772,MA0158.1;0,MA0159.1;0.569393,MA0160.1;0.823568,MA0161.1;0,MA0162.1;0.166722,MA0163.1;0.157796,MA0164.1;2.15144,MA0080.2;1.54848,MA0018.2;0.944669,MA0099.2;1.06348,MA0079.2;0.00137444,MA0102.2;2.01714,MA0258.1;0.520639,MA0259.1;0.543506,MA0442.1;0
}}

Latest revision as of 19:09, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr13:24507359..24507370,-p@chr13:24507359..24507370
-
Mm9::chr1:175560978..175561013,+p1@Pyhin1
Mm9::chr1:66109317..66109321,+p1@ENSMUST00000118496


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

no results for this coexpression

Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
hematopoietic cell3.30e-2832
hematopoietic oligopotent progenitor cell3.30e-2832
hematopoietic stem cell3.30e-2832
angioblastic mesenchymal cell3.30e-2832
hematopoietic multipotent progenitor cell3.30e-2832
hematopoietic lineage restricted progenitor cell1.91e-2425
connective tissue cell6.56e-2246
mesenchymal cell6.56e-2246
mature alpha-beta T cell4.25e-209
alpha-beta T cell4.25e-209
immature T cell4.25e-209
mature T cell4.25e-209
immature alpha-beta T cell4.25e-209
motile cell1.71e-1954
lymphoid lineage restricted progenitor cell2.96e-1812
leukocyte6.07e-1817
nongranular leukocyte6.07e-1817
CD4-positive, alpha-beta T cell7.22e-188
lymphocyte1.12e-1613
common lymphoid progenitor1.12e-1613
T cell4.25e-1611
pro-T cell4.25e-1611
thymocyte1.61e-136
double negative thymocyte1.61e-136
naive T cell1.61e-136
double-positive, alpha-beta thymocyte1.61e-136
CD4-positive, alpha-beta thymocyte1.61e-136
naive thymus-derived CD4-positive, alpha-beta T cell1.61e-136
DN4 thymocyte1.61e-136
DN1 thymic pro-T cell1.61e-136
DN2 thymocyte1.61e-136
DN3 thymocyte1.61e-136
immature single positive thymocyte1.61e-136
early T lineage precursor1.61e-136
mature CD4 single-positive thymocyte1.61e-136
resting double-positive thymocyte1.61e-136
double-positive blast1.61e-136
CD69-positive double-positive thymocyte1.61e-136
CD69-positive, CD4-positive single-positive thymocyte1.61e-136
CD4-positive, CD8-intermediate double-positive thymocyte1.61e-136
CD24-positive, CD4 single-positive thymocyte1.61e-136
stem cell1.77e-1397
nucleate cell3.93e-1316
common myeloid progenitor5.68e-1319
somatic stem cell2.09e-1191
multi fate stem cell2.09e-1191
megakaryocyte progenitor cell1.85e-106
megakaryocyte1.85e-106
somatic cell5.61e-09118
myeloid cell1.62e-0816
myeloid lineage restricted progenitor cell1.68e-0813
megakaryocyte-erythroid progenitor cell8.52e-079
animal cell9.11e-07115
eukaryotic cell9.11e-07115

Disease
Ontology termp-valuen
musculoskeletal system cancer1.57e-073
muscle cancer1.57e-073


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0699972
MA0004.10.801718
MA0006.10.60285
MA0007.10.784593
MA0009.11.27673
MA0014.10.133574
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.13.33329
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.10.714279
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.932001
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.10.337566
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.12.57794
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.10.762845
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.10.602598
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.12.61449
MA0143.11.00467
MA0144.10.541532
MA0145.10.292366
MA0146.10.151124
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.0481552
MA0138.21.07027
MA0002.20.466067
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.29236
MA0065.20.292912
MA0150.11.84475
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.925147
MA0155.10.312898
MA0156.11.58027
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.166722
MA0163.10.157796
MA0164.12.15144
MA0080.21.54848
MA0018.20.944669
MA0099.21.06348
MA0079.20.00137444
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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