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Coexpression cluster:C2051: Difference between revisions

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|full_id=C2051_CD14_CD4_Natural_CD8_Neutrophils_CD19_Peripheral
|full_id=C2051_CD14_CD4_Natural_CD8_Neutrophils_CD19_Peripheral
|id=C2051
|id=C2051
|ontology_enrichment_celltype=CL:0000738!1.18e-26!140;CL:0002087!6.83e-24!119;CL:0002031!1.93e-23!124;CL:0000037!3.64e-22!172;CL:0000566!3.64e-22!172;CL:0000988!4.03e-20!182;CL:0002032!3.26e-19!165;CL:0000837!3.26e-19!165;CL:0002057!3.48e-14!42;CL:0000766!5.69e-14!76;CL:0000860!2.82e-13!45;CL:0000839!1.09e-12!70;CL:0002009!1.62e-12!65;CL:0000557!2.39e-12!71;CL:0002194!3.75e-12!63;CL:0000576!3.75e-12!63;CL:0000040!3.75e-12!63;CL:0000559!3.75e-12!63;CL:0000838!1.28e-10!52;CL:0000542!2.08e-10!53;CL:0000051!2.08e-10!53;CL:0000763!1.34e-09!112;CL:0000049!1.34e-09!112;CL:0000791!5.59e-07!18;CL:0000789!5.59e-07!18;CL:0002420!5.59e-07!18;CL:0002419!5.59e-07!18;CL:0000790!5.59e-07!18
|ontology_enrichment_celltype=CL:0000738!1.02e-28!136;CL:0002087!3.07e-24!115;CL:0002031!1.11e-23!120;CL:0000037!2.93e-21!168;CL:0000566!2.93e-21!168;CL:0000988!6.52e-19!177;CL:0002032!1.30e-17!161;CL:0000837!1.30e-17!161;CL:0000860!5.67e-15!42;CL:0002057!5.67e-15!42;CL:0000473!1.88e-14!48;CL:0000234!1.88e-14!48;CL:0000766!2.60e-14!72;CL:0000838!4.06e-12!52;CL:0000839!1.02e-11!66;CL:0000542!1.23e-11!53;CL:0000051!1.23e-11!53;CL:0000557!1.28e-11!67;CL:0002242!1.72e-11!55;CL:0002009!3.23e-11!61;CL:0002194!5.12e-11!59;CL:0000576!5.12e-11!59;CL:0000040!5.12e-11!59;CL:0000559!5.12e-11!59;CL:0000763!1.36e-07!108;CL:0000049!1.36e-07!108;CL:0000791!1.62e-07!18;CL:0000789!1.62e-07!18;CL:0002420!1.62e-07!18;CL:0002419!1.62e-07!18;CL:0000790!1.62e-07!18;CL:0000084!3.75e-07!25;CL:0000827!3.75e-07!25;CL:0000624!7.98e-07!6
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!1.05e-15!102;UBERON:0003061!1.05e-15!102;UBERON:0002193!8.76e-15!112;UBERON:0002371!3.14e-10!80;UBERON:0001474!4.43e-10!86;UBERON:0002405!1.45e-08!115;UBERON:0004765!6.44e-07!101;UBERON:0001434!6.44e-07!101
|ontology_enrichment_uberon=UBERON:0002390!4.29e-13!98;UBERON:0003061!4.29e-13!98;UBERON:0002193!1.40e-11!108;UBERON:0002371!1.02e-09!76;UBERON:0002405!1.98e-09!93;UBERON:0001474!2.13e-09!82;UBERON:0004765!2.67e-07!90
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42,0.209692,0.248936,0.0725263,0.102587,0.0742013,0.0552936,0.0457886,0.0514927,0.324236,0.220368,0.258624,0.064656,0.226143,0.460406,0.0438521,0.435508,0.281453,0.0522771,0.0787278,0.515487,0.159873,0.142462,0.143935,0.332403,0.0379537,0.287316,0.187953,0.051459,0.114868,0.0726892,0.18732,0.32305,0.278397,0.245002,0.170848,0.487259,0.051371,0.363016,0.100188,0.223102,0.107653,0.235857,0.419621,0.191914,0.184022,0.216557,0.182956,0.116818,0.0883765,0.36316,0.0625685,0.124464,0.544477,0.173134,0.101893,0.142875,0.167635,0.171311,0.20386,0.548036,0.0685131,0.130287,0.0661526,0.0815772,0.0993937,0.122878,0.187329,0.0451012,0.0976639,0.351199,0.535567,0.415079,0.278645,0.365775,0.155708,0.248017,0.22995,0.652972,0.0760151,0.0629459,0.486024,0.0803251,0.226641,0.379174,0.0939463,0.286748,0.367925,0.0471607,0.163865,0.226359,0.22476,0.881117,0.265324,0.279778,0.141699,0.0887743,0.142302,0.0653269,0.125712,0.264432,0.0994829,0.0604041,0.144185,0.0925862,0.289561,0.199201,0.049937,0.172796,0.0595495,0.071232,0.149346,0.121978,0.22302,0.137423,0.284016,0.0754883,0.299492,0.100006,0.362866,0.197817,0.251078,0.279874,0.133127,0.410303,0.223717,0.0189842,0.196838,0.0826805,0.246601,0.193021,0.608002,0.202165,0.0946865,0.120618,0.079499,0.18762,0.195618,0.127688,0.201169,0.220353,0.24948,0.178639,0.291976,0.320355,0.364334,0.15547,0.110256,0.101581,0.14794,0.147307,0.240761,0.225961,0.124417,0.335582,0.317428,0.182843,0.130771,0.327768,0.135777,0.147842,0.0339286,0.217363,0.119015,0.690952,0.21618,0.243266,0.107021,0.0310605,0.20272,0.392453,0.248134,0.0780061,0.315336,0.230477,0.279823,0.295555,0.154895,0.724669,0.0478217,0.507599,0.170854,0.0575231,0.174063,0.514243,0.459091,0.54832,0.154964,0.296013,0.649813,0.537932,0.459994,0.523209,0.548059,0.25423,0.490559,0.45013,0.153911,0.135135,0.685908,0.747471,0.529642,0.509113,0.483077,0.590496,0.23695,0.541914,0.627201,0.304145,0.142078,0.290703,0.622694,0.366999,0.478691,0.360199,0.608176,0.657141,0.253797,0.365494,0.212703,0.56318,0.364079,0.680099,0.579886,0.104625,0.569409,0.328518,0.545608,0.310552,0.324103,0.483764,0.103928,0.453065,0.209437,0.55323,0.748403,0.598945,0.361291,0.464001,0.336867,0.579004,0.334776,0.546688,0.315519,0.261575,0.257956,0.264245,0.379063,0.326516,0.522925,0.436016,0.475063,0.202522,0.183837,0.507324,0.126097,0.3955,0.442469,0.212239,0.294954,0.156999,0.0742603,0.667777,0.39549,0.234254,0.357409,0.328421,0.721266,0.50338,0.620526,0.404625,0.759068,0.424691,0.715362,0.479581,0.62689,0.172925,0.642173,0.284496,0.512545,0.512178,0.563206,0.103692,0.684899,0.263302,0.552023,0.180735,0.189249,0.216102,0.254659,0.109605,0.397869,0.582542,0.226491,0.417131,0.463987,0.627953,0.503881,0.454761,0.639483,0.483658,0.452129,0.301581,0.261657,0.346776,0.466529,0.545655,0.438176,0.349112,0.741477,0.385425,0.307816,0.461541,0.386339,0.382854,0.598787,0.478745,0.611661,0.319747,0.475047,0.557967,0.608127,0.282281,0.612712,0.2536,0.0333324,0.564333,0.347466,0.387134,0.559969,0.358813,0.668972,0.574252,0.493455,0.346636,0.457747,0.348802,0.476541,0.579645,0.447581,0.42505,0.254628,0.713293,0.479347,0.416962,0.632833,0.0828233,0.387805,0.264038,0.22798,0.102495,0.350933,0.263896,0.0446972,0.24452,0.0613938,0.242783,0.0947248,0.336551,0.210656,0.246234,0.211271,0.281295,0.267248,0.118257,0.125087,0.215123,0.321224,0.469461,0.325254,0.266651,0.546295,0.231754,0.249415,0.283107,0.285648,0.427316,0.391071,0.279553,0.25563,0.240967,0.160955,0.256687,0.0432189,0.122439,0.16188,0.23235,0.290415,0.353147,0.112422,0.170886,0.267687,0.315656,0.284866,0.0887542,0.267811,0.338547,0.147872,0.189388,0.293546,0.210125,0.292967,0.218414,0.0509944,0.0871471,0.0689852,0.0602698,0.341188,0.259328,0.437467,0.201057,0.15696,0.129351,0.141936,0.0786166,0.276997,0.205513,0.282389,0.251421,0.162089,0.330223,0.387837,0.233244,0.207281,0.327401,0.195748,0.27845,0.161712,0.237871,0.239139,0.00468829,0.328852,0.332769,0.262022,0.274403,0.266687,0.184534,0.248707,0.31749,0.15156,0.287598,0.313858,0.223773,0.25788,0.181895,0.253768,0.30702,0.202977,0.170837,0.327002,0.28543,0.222656,0.228479,0.127111,0.259989,0.390754,0.355805,0.279739,0.108118,0.259901,0.139723,0.0708274,0.0710478,0.196248,0.102645,0.0539258,0.0709978,0.0944985,0.332746,0.271338,0.242121,0.298673,0.244395,0.106889,0.128632,0.0845989,0.159153,0.0842401,0.13698,0.0874421,0.100355,0.167854,0.142846,0.0583767,0.088258,0.117657,0.0486914,0.175784,0.262778,0.373453,0.362662,0.433518,0.184359,0.0634867,0.325785,0.257476,0.291176,0.376537,0.322827,0.229571,0.359036,0.335984,0.171704,0.208256,0.265058,0.256405,0.362898,0.302133,0.40806,0.151361,0.279606,0.286696,0.150674,0.251128,0.246177,0.35674,0.35852,0.318525,0.213257,0.287217,0.122782,0.410951,0.289049,0.266974,0.125746,0.112897,0.398354,0.222091,0.205977,0.34423,0.0936726,0.343425,0.132374,0.285122,0.22741,0.203996,0.276721,0.321965,0.264707,0.450113
}}
}}

Revision as of 12:00, 19 October 2012


Full id: C2051_CD14_CD4_Natural_CD8_Neutrophils_CD19_Peripheral



Phase1 CAGE Peaks

Hg19::chr10:27132379..27132382,-p@chr10:27132379..27132382
-
Hg19::chr13:50699656..50699670,+p5@FLJ31945
Hg19::chr2:42421500..42421503,+p@chr2:42421500..42421503
+
Hg19::chr2:42448566..42448570,+p@chr2:42448566..42448570
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
leukocyte1.02e-28136
nongranular leukocyte3.07e-24115
hematopoietic lineage restricted progenitor cell1.11e-23120
hematopoietic stem cell2.93e-21168
angioblastic mesenchymal cell2.93e-21168
hematopoietic cell6.52e-19177
hematopoietic oligopotent progenitor cell1.30e-17161
hematopoietic multipotent progenitor cell1.30e-17161
classical monocyte5.67e-1542
CD14-positive, CD16-negative classical monocyte5.67e-1542
defensive cell1.88e-1448
phagocyte1.88e-1448
myeloid leukocyte2.60e-1472
lymphoid lineage restricted progenitor cell4.06e-1252
myeloid lineage restricted progenitor cell1.02e-1166
lymphocyte1.23e-1153
common lymphoid progenitor1.23e-1153
granulocyte monocyte progenitor cell1.28e-1167
nucleate cell1.72e-1155
macrophage dendritic cell progenitor3.23e-1161
monopoietic cell5.12e-1159
monocyte5.12e-1159
monoblast5.12e-1159
promonocyte5.12e-1159
myeloid cell1.36e-07108
common myeloid progenitor1.36e-07108
mature alpha-beta T cell1.62e-0718
alpha-beta T cell1.62e-0718
immature T cell1.62e-0718
mature T cell1.62e-0718
immature alpha-beta T cell1.62e-0718
T cell3.75e-0725
pro-T cell3.75e-0725
CD4-positive, alpha-beta T cell7.98e-076
Uber Anatomy
Ontology termp-valuen
hematopoietic system4.29e-1398
blood island4.29e-1398
hemolymphoid system1.40e-11108
bone marrow1.02e-0976
immune system1.98e-0993
bone element2.13e-0982
skeletal element2.67e-0790


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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