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{{Coexpression_clusters
{
|coexpression_dpi_cluster_scores_median=0.882013742582224,

Latest revision as of 11:52, 17 September 2013


Full id: C1793_Osteoblast_Melanocyte_Preadipocyte_Adipocyte_Mesenchymal_Fibroblast_chorionic



Phase1 CAGE Peaks

Hg19::chr17:76850731..76850752,-p12@TIMP2
Hg19::chr17:76850998..76851023,-p7@TIMP2
Hg19::chr17:76851179..76851237,-p2@TIMP2
Hg19::chr17:76851601..76851636,-p@chr17:76851601..76851636
-
Hg19::chr17:76851909..76851931,-p@chr17:76851909..76851931
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
multi-cellular organism6.07e-14656
mesoderm6.37e-14315
mesoderm-derived structure6.37e-14315
presumptive mesoderm6.37e-14315
anatomical system6.56e-13624
anatomical group1.25e-12625
splanchnic layer of lateral plate mesoderm1.19e-1083
trunk mesenchyme1.62e-10122
mesenchyme3.05e-09160
entire embryonic mesenchyme3.05e-09160
epithelial vesicle4.83e-0978
vasculature1.06e-0878
vascular system1.06e-0878
germ layer1.21e-08560
germ layer / neural crest1.21e-08560
embryonic tissue1.21e-08560
presumptive structure1.21e-08560
germ layer / neural crest derived structure1.21e-08560
epiblast (generic)1.21e-08560
vessel1.59e-0868
dense mesenchyme tissue1.86e-0873
somite2.27e-0871
presomitic mesoderm2.27e-0871
presumptive segmental plate2.27e-0871
dermomyotome2.27e-0871
trunk paraxial mesoderm2.27e-0871
paraxial mesoderm2.40e-0872
presumptive paraxial mesoderm2.40e-0872
embryonic structure3.27e-08564
epithelial tube open at both ends3.57e-0859
blood vessel3.57e-0859
blood vasculature3.57e-0859
vascular cord3.57e-0859
organ component layer4.91e-0866
muscle tissue9.51e-0864
musculature9.51e-0864
musculature of body9.51e-0864
epithelial tube9.86e-08117
skeletal muscle tissue1.62e-0762
striated muscle tissue1.62e-0762
myotome1.62e-0762
artery2.81e-0742
arterial blood vessel2.81e-0742
arterial system2.81e-0742
developing anatomical structure4.28e-07581
organ7.71e-07503
trunk8.30e-07199
anatomical conduit8.32e-07240


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.136928
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.161847
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.12.41212
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.0853006
MA0056.10
MA0057.10.554727
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.11.98392
MA0069.11.09737
MA0070.12.46048
MA0071.10.695094
MA0072.11.0812
MA0073.121.2191
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.132006
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.10.520776
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.12.17648
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.11.67417
MA0145.10.143698
MA0146.10.143081
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.527987
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.514087
MA0155.11.3196
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.469165
MA0163.11.49262
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.26.70786
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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