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Coexpression cluster:C3705

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Full id: C3705_occipital_pituitary_smooth_bladder_pons_duodenum_mature



Phase1 CAGE Peaks

Hg19::chr18:11689175..11689205,+p9@GNAL
Hg19::chr18:11689217..11689247,+p6@GNAL
Hg19::chr18:11689249..11689305,+p1@GNAL


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
endo-epithelial cell8.61e-0743
Uber Anatomy
Ontology termp-valuen
adult organism1.09e-36115
central nervous system2.03e-3482
neural plate5.73e-3486
presumptive neural plate5.73e-3486
neural tube1.69e-3357
neural rod1.69e-3357
future spinal cord1.69e-3357
neural keel1.69e-3357
anterior region of body5.93e-31129
craniocervical region5.93e-31129
head6.55e-31123
neurectoderm1.19e-3090
ectoderm-derived structure3.35e-29169
regional part of nervous system3.97e-2994
nervous system3.97e-2994
regional part of brain4.10e-2859
brain4.64e-2869
future brain4.64e-2869
ectoderm2.94e-27173
presumptive ectoderm2.94e-27173
pre-chordal neural plate1.14e-2661
anterior neural tube2.93e-2542
regional part of forebrain7.24e-2541
forebrain7.24e-2541
future forebrain7.24e-2541
gray matter8.65e-2234
brain grey matter8.65e-2234
telencephalon1.49e-2134
multi-tissue structure4.92e-21347
regional part of telencephalon7.72e-2133
cerebral hemisphere1.51e-2032
organism subdivision1.59e-19365
organ3.04e-17511
cerebral cortex1.25e-1625
pallium1.25e-1625
regional part of cerebral cortex2.07e-1622
organ part3.49e-16219
embryo6.33e-16612
neocortex4.24e-1520
multi-cellular organism3.86e-14659
anatomical system8.35e-14625
anatomical group1.30e-13626
embryonic structure3.25e-13605
developing anatomical structure3.25e-13605
germ layer5.25e-13604
embryonic tissue5.25e-13604
presumptive structure5.25e-13604
epiblast (generic)5.25e-13604
cell layer1.12e-11312
epithelium1.99e-11309
organ segment3.40e-1097
anatomical cluster4.26e-10286
respiratory system7.94e-1072
endoderm-derived structure8.90e-10169
endoderm8.90e-10169
presumptive endoderm8.90e-10169
posterior neural tube2.78e-0915
chordal neural plate2.78e-0915
anatomical conduit1.26e-08241
subdivision of digestive tract1.57e-08129
endodermal part of digestive tract1.57e-08129
digestive system2.39e-08155
digestive tract2.39e-08155
primitive gut2.39e-08155
segmental subdivision of hindbrain2.25e-0712
hindbrain2.25e-0712
presumptive hindbrain2.25e-0712
respiratory tract4.24e-0753


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.