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Coexpression cluster:C2271

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Full id: C2271_heart_occipital_left_parietal_temporal_medial_caudate



Phase1 CAGE Peaks

Hg19::chr13:76378357..76378382,+p11@LMO7
Hg19::chr6:13013780..13013794,+p@chr6:13013780..13013794
+
Hg19::chr6:13013826..13013837,+p@chr6:13013826..13013837
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Hg19::chr6:13013854..13013868,+p@chr6:13013854..13013868
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism5.08e-68115
anterior neural tube6.61e-4242
regional part of forebrain8.78e-4141
forebrain8.78e-4141
future forebrain8.78e-4141
neural tube2.02e-4057
neural rod2.02e-4057
future spinal cord2.02e-4057
neural keel2.02e-4057
telencephalon2.13e-3734
regional part of telencephalon6.16e-3633
cerebral hemisphere1.52e-3532
regional part of brain5.64e-3559
central nervous system7.14e-3582
gray matter1.24e-3434
brain grey matter1.24e-3434
brain1.44e-3269
future brain1.44e-3269
neural plate1.27e-3186
presumptive neural plate1.27e-3186
regional part of nervous system1.63e-3194
nervous system1.63e-3194
regional part of cerebral cortex8.34e-3122
neurectoderm9.74e-3190
neocortex3.65e-2820
pre-chordal neural plate8.12e-2861
cerebral cortex2.76e-2625
pallium2.76e-2625
anterior region of body5.39e-17129
craniocervical region5.39e-17129
head4.91e-16123
ectoderm-derived structure6.13e-16169
ectoderm7.65e-16173
presumptive ectoderm7.65e-16173
tube3.31e-14194
basal ganglion1.11e-129
nuclear complex of neuraxis1.11e-129
aggregate regional part of brain1.11e-129
collection of basal ganglia1.11e-129
cerebral subcortex1.11e-129
anatomical conduit1.42e-11241
anatomical cluster8.05e-11286
gyrus4.19e-106
telencephalic nucleus4.54e-107
temporal lobe9.77e-107
nucleus of brain1.05e-099
neural nucleus1.05e-099
occipital lobe8.02e-095
parietal lobe8.14e-095
epithelium1.21e-08309
cell layer2.25e-08312
limbic system2.92e-085
organ6.58e-08511
corpus striatum5.56e-074
striatum5.56e-074
ventral part of telencephalon5.56e-074
future corpus striatum5.56e-074


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.