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Coexpression cluster:C661

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Full id: C661_acute_lung_Dendritic_placenta_granulocyte_Adipocyte_small



Phase1 CAGE Peaks

Hg19::chr12:1992387..1992427,-p@chr12:1992387..1992427
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Hg19::chr12:29376592..29376620,+p6@FAR2
Hg19::chr12:29376673..29376683,+p10@FAR2
Hg19::chr13:72516905..72516908,+p@chr13:72516905..72516908
+
Hg19::chr13:91972321..91972358,-p@chr13:91972321..91972358
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Hg19::chr1:86622421..86622460,-p1@COL24A1
Hg19::chr7:95709647..95709654,+p@chr7:95709647..95709654
+
Hg19::chr7:95709659..95709664,+p@chr7:95709659..95709664
+
Hg19::chr7:95709671..95709682,+p@chr7:95709671..95709682
+
Hg19::chr7:96656706..96656712,+p@chr7:96656706..96656712
+
Hg19::chr7:96656740..96656782,+p@chr7:96656740..96656782
+
Hg19::chr8:1959291..1959319,+p@chr8:1959291..1959319
+
Hg19::chr8:20773511..20773520,+p@chr8:20773511..20773520
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0006817phosphate transport0.0412005965697241
GO:0015698inorganic anion transport0.0412005965697241
GO:0006820anion transport0.0412005965697241



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
bone element1.01e-1886
telencephalon1.04e-1734
bone marrow1.43e-1780
cerebral hemisphere1.89e-1732
gray matter2.42e-1734
brain grey matter2.42e-1734
regional part of telencephalon4.47e-1733
skeletal element1.80e-16101
skeletal system1.80e-16101
regional part of forebrain9.32e-1641
forebrain9.32e-1641
future forebrain9.32e-1641
adult organism5.11e-15115
anterior neural tube5.30e-1542
cerebral cortex5.60e-1525
pallium5.60e-1525
hematopoietic system1.00e-14102
blood island1.00e-14102
neural tube2.01e-1457
neural rod2.01e-1457
future spinal cord2.01e-1457
neural keel2.01e-1457
regional part of cerebral cortex6.12e-1422
regional part of brain8.65e-1359
neocortex1.61e-1220
hemolymphoid system1.13e-11112
brain1.93e-1169
future brain1.93e-1169
central nervous system1.04e-0982
regional part of nervous system1.85e-0994
nervous system1.85e-0994
pre-chordal neural plate1.91e-0961
musculoskeletal system1.91e-09167
neural plate1.69e-0886
presumptive neural plate1.69e-0886
immune system3.88e-08115
neurectoderm1.15e-0790


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.