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Coexpression cluster:C2892

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Full id: C2892_caudate_hippocampus_putamen_amygdala_testis_granulosa_skeletal



Phase1 CAGE Peaks

Hg19::chr7:29845929..29845940,+p4@WIPF3
Hg19::chr7:29846099..29846181,+p1@WIPF3
Hg19::chr7:29874392..29874406,+p9@WIPF3
Hg19::chr7:29954723..29954724,+p@chr7:29954723..29954724
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism4.20e-46115
neural tube5.40e-3357
neural rod5.40e-3357
future spinal cord5.40e-3357
neural keel5.40e-3357
regional part of nervous system4.11e-3194
nervous system4.11e-3194
central nervous system8.86e-3182
neural plate5.14e-2986
presumptive neural plate5.14e-2986
neurectoderm8.30e-2990
anterior neural tube3.38e-2842
regional part of forebrain4.17e-2841
forebrain4.17e-2841
future forebrain4.17e-2841
regional part of brain4.32e-2659
telencephalon1.64e-2434
gray matter4.27e-2434
brain grey matter4.27e-2434
brain6.85e-2469
future brain6.85e-2469
regional part of telencephalon7.67e-2433
cerebral hemisphere1.24e-2332
pre-chordal neural plate2.51e-2361
ectoderm1.17e-20173
presumptive ectoderm1.17e-20173
ectoderm-derived structure1.95e-20169
cerebral cortex1.66e-1825
pallium1.66e-1825
regional part of cerebral cortex1.00e-1722
anterior region of body6.19e-17129
craniocervical region6.19e-17129
head6.45e-17123
neocortex3.45e-1620
organ part7.44e-11219
organ1.12e-09511
organism subdivision1.55e-09365
multi-tissue structure3.40e-09347
embryo1.80e-08612
multi-cellular organism3.38e-08659
basal ganglion9.86e-089
nuclear complex of neuraxis9.86e-089
aggregate regional part of brain9.86e-089
collection of basal ganglia9.86e-089
cerebral subcortex9.86e-089
body cavity1.56e-0746
tube3.10e-07194
body cavity or lining3.55e-0749
anatomical cavity3.62e-0770
temporal lobe4.44e-077
anatomical conduit4.59e-07241
nucleus of brain4.94e-079
neural nucleus4.94e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.