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MCL coexpression mm9:1427

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Phase1 CAGE Peaks

 Short description
Mm9::chr1:42751793..42751859,-p4@2610017I09Rik
Mm9::chr7:25292118..25292129,+p8@Zfp428
Mm9::chr7:25292160..25292213,+p3@Zfp428
Mm9::chr7:25292223..25292234,+p7@Zfp428
Mm9::chr8:12395843..12395852,+p7@Sox1
Mm9::chr8:12396320..12396363,+p1@ENSMUST00000174915


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0021884forebrain neuron development0.0245392040544787
GO:0021879forebrain neuron differentiation0.0245392040544787
GO:0021872generation of neurons in the forebrain0.0245392040544787
GO:0021954central nervous system neuron development0.0441512032660378
GO:0021953central nervous system neuron differentiation0.0441512032660378



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system7.55e-3773
nervous system2.68e-3675
ectoderm-derived structure6.32e-3295
ectoderm6.32e-3295
presumptive ectoderm6.32e-3295
neurectoderm2.02e-2964
neural plate2.02e-2964
presumptive neural plate2.02e-2964
regional part of nervous system3.70e-2854
neural tube1.24e-2652
neural rod1.24e-2652
future spinal cord1.24e-2652
neural keel1.24e-2652
ecto-epithelium3.13e-2673
brain9.38e-2447
future brain9.38e-2447
regional part of brain4.19e-2346
pre-chordal neural plate3.77e-2249
anterior neural tube1.09e-2040
structure with developmental contribution from neural crest1.20e-2092
gray matter3.13e-2034
regional part of forebrain4.07e-2039
forebrain4.07e-2039
future forebrain4.07e-2039
brain grey matter2.03e-1729
regional part of telencephalon2.03e-1729
telencephalon2.03e-1729
cerebral cortex1.22e-1221
cerebral hemisphere1.22e-1221
pallium1.22e-1221
regional part of cerebral cortex4.21e-1017


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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