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MCL coexpression mm9:532

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:69794834..69794871,+p5@Ctdnep1
Mm9::chr11:97857366..97857389,-p3@Arl5c
Mm9::chr1:74283176..74283202,+p2@Arpc2
Mm9::chr4:144836758..144836782,-p1@Tnfrsf1b
Mm9::chr5:106160848..106160866,+p13@Lrrc8d
Mm9::chr5:53981592..53981616,+p3@Rbpj
Mm9::chr6:129132950..129132968,+p@chr6:129132950..129132968
+
Mm9::chr6:129188176..129188217,+p@chr6:129188176..129188217
+
Mm9::chr7:109397876..109397888,-p@chr7:109397876..109397888
-
Mm9::chrX:104344399..104344411,+p9@A630033H20Rik
Mm9::chrX:98460079..98460088,-p@chrX:98460079..98460088
-
Mm9::chrX:98460133..98460154,-p@chrX:98460133..98460154
-
Mm9::chrX:98460249..98460271,-p@chrX:98460249..98460271
-
Mm9::chrX:98461002..98461015,-p@chrX:98461002..98461015
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050779RNA destabilization0.0498275096566748
GO:0043120tumor necrosis factor binding0.0498275096566748
GO:0005031tumor necrosis factor receptor activity0.0498275096566748
GO:0005035death receptor activity0.0498275096566748
GO:0048505regulation of timing of cell differentiation0.0498275096566748
GO:0040034regulation of development, heterochronic0.0498275096566748



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
hematopoietic cell4.10e-1532
hematopoietic oligopotent progenitor cell4.10e-1532
hematopoietic stem cell4.10e-1532
angioblastic mesenchymal cell4.10e-1532
hematopoietic multipotent progenitor cell4.10e-1532
leukocyte4.40e-1517
nongranular leukocyte4.40e-1517
hematopoietic lineage restricted progenitor cell1.13e-1425
lymphoid lineage restricted progenitor cell2.08e-1412
T cell2.64e-1311
pro-T cell2.64e-1311
lymphocyte5.59e-1313
common lymphoid progenitor5.59e-1313
connective tissue cell6.41e-1346
mesenchymal cell6.41e-1346
mature alpha-beta T cell5.93e-129
alpha-beta T cell5.93e-129
immature T cell5.93e-129
mature T cell5.93e-129
immature alpha-beta T cell5.93e-129
CD4-positive, alpha-beta T cell8.44e-118
motile cell1.94e-1054
nucleate cell8.64e-1016
thymocyte1.34e-086
double negative thymocyte1.34e-086
naive T cell1.34e-086
double-positive, alpha-beta thymocyte1.34e-086
CD4-positive, alpha-beta thymocyte1.34e-086
naive thymus-derived CD4-positive, alpha-beta T cell1.34e-086
DN4 thymocyte1.34e-086
DN1 thymic pro-T cell1.34e-086
DN2 thymocyte1.34e-086
DN3 thymocyte1.34e-086
immature single positive thymocyte1.34e-086
early T lineage precursor1.34e-086
mature CD4 single-positive thymocyte1.34e-086
resting double-positive thymocyte1.34e-086
double-positive blast1.34e-086
CD69-positive double-positive thymocyte1.34e-086
CD69-positive, CD4-positive single-positive thymocyte1.34e-086
CD4-positive, CD8-intermediate double-positive thymocyte1.34e-086
CD24-positive, CD4 single-positive thymocyte1.34e-086

Uber Anatomy
Ontology termp-valuen
hemolymphoid system1.17e-2748
immune system1.17e-2748
hematopoietic system1.08e-2445
blood island1.08e-2445
lateral plate mesoderm6.91e-1887
hemopoietic organ1.15e-1629
immune organ1.15e-1629
mixed endoderm/mesoderm-derived structure2.60e-1635
pharynx6.37e-1524
upper respiratory tract6.37e-1524
chordate pharynx6.37e-1524
pharyngeal arch system6.37e-1524
pharyngeal region of foregut6.37e-1524
thymus2.28e-1423
neck2.28e-1423
respiratory system epithelium2.28e-1423
hemolymphoid system gland2.28e-1423
pharyngeal epithelium2.28e-1423
thymic region2.28e-1423
pharyngeal gland2.28e-1423
entire pharyngeal arch endoderm2.28e-1423
thymus primordium2.28e-1423
early pharyngeal endoderm2.28e-1423
respiratory tract9.38e-1441
gland of gut1.67e-1324
respiratory system3.23e-1342
connective tissue6.41e-1346
segment of respiratory tract1.57e-1227
mesoderm5.94e-11120
mesoderm-derived structure5.94e-11120
presumptive mesoderm5.94e-11120
bone marrow1.35e-0816
organ segment3.00e-0835
craniocervical region7.41e-0836
foregut1.96e-0780
musculoskeletal system2.96e-0732


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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