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MCL coexpression mm9:612

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:112909747..112909802,-p@chr12:112909747..112909802
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Mm9::chr12:81620208..81620217,+p@chr12:81620208..81620217
+
Mm9::chr15:30387606..30387623,+p@chr15:30387606..30387623
+
Mm9::chr5:138199481..138199491,+p16@Tsc22d4
Mm9::chr5:143040448..143040453,-p@chr5:143040448..143040453
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Mm9::chr5:143084702..143084734,-p1@Mmd2
Mm9::chr5:143084739..143084762,-p2@Mmd2
Mm9::chr7:4071127..4071157,+p2@Ttyh1
Mm9::chr7:4071158..4071198,+p1@Ttyh1
Mm9::chr7:4071200..4071211,+p3@Ttyh1
Mm9::chr8:97519491..97519521,+p@chr8:97519491..97519521
+
Mm9::chr9:54509473..54509523,-p1@Acsbg1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0032433filopodium tip0.014134662795157
GO:0031527filopodium membrane0.014134662795157
GO:0031957very-long-chain-fatty-acid-CoA ligase activity0.014134662795157
GO:0004111creatine kinase activity0.0423285488713615
GO:0000038very-long-chain fatty acid metabolic process0.0423285488713615
GO:0046847filopodium formation0.0423285488713615
GO:0030035microspike biogenesis0.0423285488713615
GO:0031253cell projection membrane0.0423285488713615
GO:0006970response to osmotic stress0.0423285488713615
GO:0004467long-chain-fatty-acid-CoA ligase activity0.0423285488713615
GO:0030175filopodium0.0423285488713615
GO:0015645fatty-acid ligase activity0.0423285488713615
GO:0001676long-chain fatty acid metabolic process0.0423285488713615
GO:0016775phosphotransferase activity, nitrogenous group as acceptor0.0423285488713615



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system3.22e-3775
central nervous system3.60e-3773
ectoderm-derived structure9.25e-3195
ectoderm9.25e-3195
presumptive ectoderm9.25e-3195
regional part of nervous system3.30e-2854
neurectoderm7.28e-2764
neural plate7.28e-2764
presumptive neural plate7.28e-2764
neural tube1.08e-2652
neural rod1.08e-2652
future spinal cord1.08e-2652
neural keel1.08e-2652
ecto-epithelium8.49e-2473
brain3.96e-2347
future brain3.96e-2347
regional part of brain1.51e-2246
gray matter7.08e-2034
anterior neural tube7.39e-1940
structure with developmental contribution from neural crest1.56e-1892
pre-chordal neural plate2.23e-1849
regional part of forebrain3.17e-1839
forebrain3.17e-1839
future forebrain3.17e-1839
brain grey matter1.44e-1629
regional part of telencephalon1.44e-1629
telencephalon1.44e-1629
cerebral cortex3.27e-1221
cerebral hemisphere3.27e-1221
pallium3.27e-1221
regional part of cerebral cortex1.88e-1017
posterior neural tube2.17e-0812
chordal neural plate2.17e-0812
multi-cellular organism1.08e-07333
occipital lobe1.31e-0710
visual cortex1.31e-0710
neocortex1.31e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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