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MCL coexpression mm9:935

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:38606893..38606928,+p4@Dgkb
Mm9::chr14:31951511..31951534,+p@chr14:31951511..31951534
+
Mm9::chr14:31951544..31951561,+p@chr14:31951544..31951561
+
Mm9::chr4:126421474..126421488,-p@chr4:126421474..126421488
-
Mm9::chr4:126429321..126429353,-p@chr4:126429321..126429353
-
Mm9::chr4:126429355..126429362,-p@chr4:126429355..126429362
-
Mm9::chr4:128799308..128799339,-p3@Hpca
Mm9::chr7:68749528..68749541,-p1@uc009hez.1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007205protein kinase C activation0.0337567961805886
GO:0004143diacylglycerol kinase activity0.0337567961805886
GO:0045453bone resorption0.0337567961805886
GO:0001894tissue homeostasis0.0337567961805886
GO:0048871multicellular organismal homeostasis0.0337567961805886
GO:0007200G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)0.0337567961805886
GO:0032147activation of protein kinase activity0.0337567961805886
GO:0048015phosphoinositide-mediated signaling0.039350554041878
GO:0019992diacylglycerol binding0.039350554041878



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)1.76e-1323
neuroblast (sensu Vertebrata)1.76e-1323
neuron1.86e-0733
neuronal stem cell1.86e-0733
neuroblast1.86e-0733
electrically signaling cell1.86e-0733

Uber Anatomy
Ontology termp-valuen
regional part of nervous system3.08e-2954
neural tube5.17e-2752
neural rod5.17e-2752
future spinal cord5.17e-2752
neural keel5.17e-2752
neurectoderm1.56e-2564
neural plate1.56e-2564
presumptive neural plate1.56e-2564
central nervous system2.05e-2573
nervous system2.95e-2575
brain6.25e-2347
future brain6.25e-2347
regional part of brain5.36e-2246
ectoderm-derived structure2.78e-2195
ectoderm2.78e-2195
presumptive ectoderm2.78e-2195
ecto-epithelium2.48e-2073
gray matter3.17e-2034
pre-chordal neural plate3.55e-1949
anterior neural tube1.42e-1840
regional part of forebrain1.55e-1739
forebrain1.55e-1739
future forebrain1.55e-1739
brain grey matter1.83e-1629
regional part of telencephalon1.83e-1629
telencephalon1.83e-1629
structure with developmental contribution from neural crest1.50e-1392
cerebral cortex1.67e-1121
cerebral hemisphere1.67e-1121
pallium1.67e-1121
occipital lobe8.37e-1110
visual cortex8.37e-1110
neocortex8.37e-1110
regional part of cerebral cortex2.44e-1017
posterior neural tube4.69e-0912
chordal neural plate4.69e-0912
tube4.77e-08114


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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