MCL coexpression mm9:1036
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:6373383..6373454,- | p1@Mthfd1l |
| Mm9::chr14:52817186..52817193,+ | p1@ENSMUST00000143086 p1@uc007tos.1 |
| Mm9::chr15:79913772..79913789,- | p1@Gm12816 p1@LOC674810 p1@Rpl3 |
| Mm9::chr17:24665188..24665209,+ | p1@2610019E17Rik |
| Mm9::chr17:24856834..24856861,- | p1@Snhg9 |
| Mm9::chr3:123211248..123211259,- | p1@Snhg8 |
| Mm9::chr9:88417714..88417733,- | p1@ENSMUST00000034997 p1@uc009qys.1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0044249 | cellular biosynthetic process | 0.00253564774886875 |
| GO:0009257 | 10-formyltetrahydrofolate biosynthetic process | 0.00253564774886875 |
| GO:0003735 | structural constituent of ribosome | 0.00253564774886875 |
| GO:0005840 | ribosome | 0.00253564774886875 |
| GO:0009058 | biosynthetic process | 0.00253564774886875 |
| GO:0009256 | 10-formyltetrahydrofolate metabolic process | 0.00253564774886875 |
| GO:0004329 | formate-tetrahydrofolate ligase activity | 0.00253564774886875 |
| GO:0009396 | folic acid and derivative biosynthetic process | 0.00776329406794076 |
| GO:0006412 | translation | 0.00887039156264768 |
| GO:0030529 | ribonucleoprotein complex | 0.00887039156264768 |
| GO:0006760 | folic acid and derivative metabolic process | 0.00887039156264768 |
| GO:0009059 | macromolecule biosynthetic process | 0.0161856074324591 |
| GO:0044444 | cytoplasmic part | 0.0195166510969675 |
| GO:0006752 | group transfer coenzyme metabolic process | 0.0341338087604507 |
| GO:0046483 | heterocycle metabolic process | 0.0389122065212837 |
| GO:0006730 | one-carbon compound metabolic process | 0.0425345502092769 |
| GO:0009108 | coenzyme biosynthetic process | 0.0431377310490122 |
| GO:0051188 | cofactor biosynthetic process | 0.0470887349534143 |
| GO:0043232 | intracellular non-membrane-bound organelle | 0.0474648560494127 |
| GO:0043228 | non-membrane-bound organelle | 0.0474648560494127 |
| GO:0006725 | aromatic compound metabolic process | 0.0474648560494127 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| hematopoietic cell | 1.78e-14 | 32 |
| hematopoietic oligopotent progenitor cell | 1.78e-14 | 32 |
| hematopoietic stem cell | 1.78e-14 | 32 |
| angioblastic mesenchymal cell | 1.78e-14 | 32 |
| hematopoietic multipotent progenitor cell | 1.78e-14 | 32 |
| nucleate cell | 7.43e-11 | 16 |
| hematopoietic lineage restricted progenitor cell | 2.02e-10 | 25 |
| connective tissue cell | 3.62e-09 | 46 |
| mesenchymal cell | 3.62e-09 | 46 |
| lymphocyte | 9.19e-09 | 13 |
| common lymphoid progenitor | 9.19e-09 | 13 |
| lymphoid lineage restricted progenitor cell | 2.15e-08 | 12 |
| T cell | 7.10e-08 | 11 |
| pro-T cell | 7.10e-08 | 11 |
| common myeloid progenitor | 3.44e-07 | 19 |
| motile cell | 5.54e-07 | 54 |
| mature alpha-beta T cell | 6.80e-07 | 9 |
| alpha-beta T cell | 6.80e-07 | 9 |
| immature T cell | 6.80e-07 | 9 |
| mature T cell | 6.80e-07 | 9 |
| immature alpha-beta T cell | 6.80e-07 | 9 |
| Ontology term | p-value | n |
|---|---|---|
| hematopoietic system | 4.35e-10 | 45 |
| blood island | 4.35e-10 | 45 |
| hemolymphoid system | 1.48e-09 | 48 |
| immune system | 1.48e-09 | 48 |
| connective tissue | 3.62e-09 | 46 |
| hemopoietic organ | 7.74e-09 | 29 |
| immune organ | 7.74e-09 | 29 |
| segment of respiratory tract | 2.88e-07 | 27 |
| mixed endoderm/mesoderm-derived structure | 7.23e-07 | 35 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.339775 |
| MA0004.1 | 1.20906 |
| MA0006.1 | 0.837454 |
| MA0007.1 | 0.465969 |
| MA0009.1 | 0.92425 |
| MA0014.1 | 0.0886247 |
| MA0017.1 | 0.337808 |
| MA0019.1 | 0.740036 |
| MA0024.1 | 0.880057 |
| MA0025.1 | 1.15921 |
| MA0027.1 | 2.57545 |
| MA0028.1 | 1.55156 |
| MA0029.1 | 0.858105 |
| MA0030.1 | 0.864739 |
| MA0031.1 | 0.828781 |
| MA0038.1 | 0.62758 |
| MA0040.1 | 0.936879 |
| MA0041.1 | 0.404721 |
| MA0042.1 | 0.391504 |
| MA0043.1 | 1.02178 |
| MA0046.1 | 0.960497 |
| MA0048.1 | 0.128106 |
| MA0050.1 | 0.520357 |
| MA0051.1 | 0.636645 |
| MA0052.1 | 0.945011 |
| MA0055.1 | 0.157978 |
| MA0056.1 | 0 |
| MA0057.1 | 0.117936 |
| MA0058.1 | 1.77195 |
| MA0059.1 | 0.397033 |
| MA0060.1 | 1.22438 |
| MA0061.1 | 1.33382 |
| MA0063.1 | 0 |
| MA0066.1 | 0.616444 |
| MA0067.1 | 1.27078 |
| MA0068.1 | 0.121435 |
| MA0069.1 | 0.945354 |
| MA0070.1 | 0.93557 |
| MA0071.1 | 0.519509 |
| MA0072.1 | 0.927016 |
| MA0073.1 | 0.0004304 |
| MA0074.1 | 0.580087 |
| MA0076.1 | 0.938908 |
| MA0077.1 | 0.905143 |
| MA0078.1 | 0.670113 |
| MA0081.1 | 0.420276 |
| MA0083.1 | 1.02098 |
| MA0084.1 | 1.59945 |
| MA0087.1 | 0.977537 |
| MA0088.1 | 0.0841779 |
| MA0089.1 | 0 |
| MA0090.1 | 1.1347 |
| MA0091.1 | 0.494398 |
| MA0092.1 | 0.446857 |
| MA0093.1 | 1.58083 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.568369 |
| MA0101.1 | 1.0468 |
| MA0103.1 | 0.348572 |
| MA0105.1 | 0.162418 |
| MA0106.1 | 0.677988 |
| MA0107.1 | 0.906859 |
| MA0108.2 | 4.33655 |
| MA0109.1 | 0 |
| MA0111.1 | 0.460823 |
| MA0113.1 | 0.649407 |
| MA0114.1 | 0.719313 |
| MA0115.1 | 1.0246 |
| MA0116.1 | 1.51389 |
| MA0117.1 | 0.992087 |
| MA0119.1 | 1.04809 |
| MA0122.1 | 1.01209 |
| MA0124.1 | 1.21735 |
| MA0125.1 | 1.14291 |
| MA0130.1 | 0 |
| MA0131.1 | 1.74348 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.05845 |
| MA0136.1 | 0.600242 |
| MA0139.1 | 0.202522 |
| MA0140.1 | 0.568252 |
| MA0141.1 | 0.368264 |
| MA0142.1 | 0.814115 |
| MA0143.1 | 0.665982 |
| MA0144.1 | 0.262477 |
| MA0145.1 | 0.0910975 |
| MA0146.1 | 0.0256827 |
| MA0147.1 | 0.753844 |
| MA0148.1 | 0.49752 |
| MA0149.1 | 0.411562 |
| MA0062.2 | 2.20069 |
| MA0035.2 | 0.573016 |
| MA0039.2 | 1.37408 |
| MA0138.2 | 0.727395 |
| MA0002.2 | 0.592533 |
| MA0137.2 | 0.365364 |
| MA0104.2 | 0.624968 |
| MA0047.2 | 0.626803 |
| MA0112.2 | 0.0910939 |
| MA0065.2 | 0.305574 |
| MA0150.1 | 0.465855 |
| MA0151.1 | 0 |
| MA0152.1 | 0.626912 |
| MA0153.1 | 1.07519 |
| MA0154.1 | 0.397336 |
| MA0155.1 | 0.102995 |
| MA0156.1 | 0.936991 |
| MA0157.1 | 0.781683 |
| MA0158.1 | 0 |
| MA0159.1 | 0.776527 |
| MA0160.1 | 0.50056 |
| MA0161.1 | 0 |
| MA0162.1 | 1.26636 |
| MA0163.1 | 0.116706 |
| MA0164.1 | 0.600609 |
| MA0080.2 | 0.908823 |
| MA0018.2 | 0.610433 |
| MA0099.2 | 0.721008 |
| MA0079.2 | 0.065018 |
| MA0102.2 | 1.65195 |
| MA0258.1 | 0.246285 |
| MA0259.1 | 1.34223 |
| MA0442.1 | 0 |
