Coexpression cluster:C10: Difference between revisions
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|ontology_enrichment_uberon=UBERON:0000073!1.02e-45!94;UBERON:0001016!1.02e-45!94;UBERON:0005743!6.43e-44!86;UBERON:0001017!5.05e-43!82;UBERON:0002346!4.07e-37!90;UBERON:0003075!2.09e-35!86;UBERON:0007284!2.09e-35!86;UBERON:0000955!2.44e-35!69;UBERON:0006238!2.44e-35!69;UBERON:0001049!5.23e-35!57;UBERON:0005068!5.23e-35!57;UBERON:0006241!5.23e-35!57;UBERON:0007135!5.23e-35!57;UBERON:0007023!7.29e-33!115;UBERON:0000924!2.14e-32!173;UBERON:0006601!2.14e-32!173;UBERON:0002616!4.24e-32!59;UBERON:0004121!9.57e-31!169;UBERON:0003080!9.61e-27!42;UBERON:0002780!1.49e-26!41;UBERON:0001890!1.49e-26!41;UBERON:0006240!1.49e-26!41;UBERON:0003056!1.09e-25!61;UBERON:0000033!1.91e-25!123;UBERON:0000153!2.01e-25!129;UBERON:0007811!2.01e-25!129;UBERON:0001893!9.75e-23!34;UBERON:0002020!1.03e-22!34;UBERON:0003528!1.03e-22!34;UBERON:0002791!4.23e-22!33;UBERON:0001869!1.10e-21!32;UBERON:0000475!1.75e-19!365;UBERON:0000956!1.74e-17!25;UBERON:0000203!1.74e-17!25;UBERON:0002619!4.19e-16!22;UBERON:0000119!8.50e-16!312;UBERON:0000483!1.05e-15!309;UBERON:0000025!3.05e-15!194;UBERON:0001950!7.80e-15!20;UBERON:0000481!5.98e-13!347;UBERON:0004111!2.59e-12!241;UBERON:0000064!3.68e-12!219;UBERON:0000477!9.37e-12!286;UBERON:0000468!6.98e-11!659;UBERON:0003076!2.68e-09!15;UBERON:0003057!2.68e-09!15;UBERON:0000922!8.78e-09!612;UBERON:0004732!3.79e-08!13;UBERON:0004733!1.20e-07!12;UBERON:0002028!1.20e-07!12;UBERON:0007277!1.20e-07!12;UBERON:0000467!3.57e-07!625;UBERON:0002050!4.36e-07!605;UBERON:0005423!4.36e-07!605;UBERON:0000480!5.49e-07!626;UBERON:0000923!7.50e-07!604;UBERON:0005291!7.50e-07!604;UBERON:0006598!7.50e-07!604;UBERON:0002532!7.50e-07!604;UBERON:0002420!7.55e-07!9;UBERON:0007245!7.55e-07!9;UBERON:0010009!7.55e-07!9;UBERON:0010011!7.55e-07!9;UBERON:0000454!7.55e-07!9 | |ontology_enrichment_uberon=UBERON:0000073!1.02e-45!94;UBERON:0001016!1.02e-45!94;UBERON:0005743!6.43e-44!86;UBERON:0001017!5.05e-43!82;UBERON:0002346!4.07e-37!90;UBERON:0003075!2.09e-35!86;UBERON:0007284!2.09e-35!86;UBERON:0000955!2.44e-35!69;UBERON:0006238!2.44e-35!69;UBERON:0001049!5.23e-35!57;UBERON:0005068!5.23e-35!57;UBERON:0006241!5.23e-35!57;UBERON:0007135!5.23e-35!57;UBERON:0007023!7.29e-33!115;UBERON:0000924!2.14e-32!173;UBERON:0006601!2.14e-32!173;UBERON:0002616!4.24e-32!59;UBERON:0004121!9.57e-31!169;UBERON:0003080!9.61e-27!42;UBERON:0002780!1.49e-26!41;UBERON:0001890!1.49e-26!41;UBERON:0006240!1.49e-26!41;UBERON:0003056!1.09e-25!61;UBERON:0000033!1.91e-25!123;UBERON:0000153!2.01e-25!129;UBERON:0007811!2.01e-25!129;UBERON:0001893!9.75e-23!34;UBERON:0002020!1.03e-22!34;UBERON:0003528!1.03e-22!34;UBERON:0002791!4.23e-22!33;UBERON:0001869!1.10e-21!32;UBERON:0000475!1.75e-19!365;UBERON:0000956!1.74e-17!25;UBERON:0000203!1.74e-17!25;UBERON:0002619!4.19e-16!22;UBERON:0000119!8.50e-16!312;UBERON:0000483!1.05e-15!309;UBERON:0000025!3.05e-15!194;UBERON:0001950!7.80e-15!20;UBERON:0000481!5.98e-13!347;UBERON:0004111!2.59e-12!241;UBERON:0000064!3.68e-12!219;UBERON:0000477!9.37e-12!286;UBERON:0000468!6.98e-11!659;UBERON:0003076!2.68e-09!15;UBERON:0003057!2.68e-09!15;UBERON:0000922!8.78e-09!612;UBERON:0004732!3.79e-08!13;UBERON:0004733!1.20e-07!12;UBERON:0002028!1.20e-07!12;UBERON:0007277!1.20e-07!12;UBERON:0000467!3.57e-07!625;UBERON:0002050!4.36e-07!605;UBERON:0005423!4.36e-07!605;UBERON:0000480!5.49e-07!626;UBERON:0000923!7.50e-07!604;UBERON:0005291!7.50e-07!604;UBERON:0006598!7.50e-07!604;UBERON:0002532!7.50e-07!604;UBERON:0002420!7.55e-07!9;UBERON:0007245!7.55e-07!9;UBERON:0010009!7.55e-07!9;UBERON:0010011!7.55e-07!9;UBERON:0000454!7.55e-07!9 | ||
|pathway_enrichment=1.50639613609536e-06;0.000476774377074182;9;87;ErbB signaling pathway (KEGG):04012!4.03493974149437e-05;0.00363855950489331;9;130;Axon guidance (KEGG):04360!0.000140886082119045;0.00990898777570619;7;90;Gap junction (KEGG):04540!0.000248948414545059;0.0143258496733657;6;70;Long-term potentiation (KEGG):04720!4.51163032377388e-06;0.00095195399831629;10;126;Glutamatergic synapse (KEGG):04724!0.000540350719019034;0.028503500428254;7;112;Wnt Signaling Pathway NetPath (Wikipathways):WP363!0.000795690400175516;0.0387440017931617;3;15;GPCRs, Class C Metabotropic glutamate, pheromone (Wikipathways):WP501!4.59849542482566e-05;0.00363855950489331;5;32;Hypothetical Network for Drug Addiction (Wikipathways):WP666!8.01823943464713e-06;0.00101510911242633;12;197;Synaptic Transmission (Reactome):REACT_13685!5.4385689802965e-14;3.44261416452769e-11;24;265;Axon guidance (Reactome):REACT_18266!2.33856132254937e-05;0.00246718219528959;5;28;{DLG4,28} (Static Module):NA!0.000219863517977324;0.0139173606879646;3;10;{PAK2,10} (Static Module):NA!6.8388258594864e-06;0.00101510911242633;10;132;{RAC1,133} (Static Module):NA | |pathway_enrichment=1.50639613609536e-06;0.000476774377074182;9;87;ErbB signaling pathway (KEGG):04012!4.03493974149437e-05;0.00363855950489331;9;130;Axon guidance (KEGG):04360!0.000140886082119045;0.00990898777570619;7;90;Gap junction (KEGG):04540!0.000248948414545059;0.0143258496733657;6;70;Long-term potentiation (KEGG):04720!4.51163032377388e-06;0.00095195399831629;10;126;Glutamatergic synapse (KEGG):04724!0.000540350719019034;0.028503500428254;7;112;Wnt Signaling Pathway NetPath (Wikipathways):WP363!0.000795690400175516;0.0387440017931617;3;15;GPCRs, Class C Metabotropic glutamate, pheromone (Wikipathways):WP501!4.59849542482566e-05;0.00363855950489331;5;32;Hypothetical Network for Drug Addiction (Wikipathways):WP666!8.01823943464713e-06;0.00101510911242633;12;197;Synaptic Transmission (Reactome):REACT_13685!5.4385689802965e-14;3.44261416452769e-11;24;265;Axon guidance (Reactome):REACT_18266!2.33856132254937e-05;0.00246718219528959;5;28;{DLG4,28} (Static Module):NA!0.000219863517977324;0.0139173606879646;3;10;{PAK2,10} (Static Module):NA!6.8388258594864e-06;0.00101510911242633;10;132;{RAC1,133} (Static Module):NA | ||
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Revision as of 16:53, 8 August 2012
Full id: C10_occipital_temporal_parietal_brain_duodenum_Neurons_Neural
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
p.value | FDR | nGenes | nPathway | Name |
---|---|---|---|---|
1.50639613609536e-06 | 0.000476774377074182 | 9 | 87 | ErbB signaling pathway (KEGG):04012 |
4.03493974149437e-05 | 0.00363855950489331 | 9 | 130 | Axon guidance (KEGG):04360 |
0.000140886082119045 | 0.00990898777570619 | 7 | 90 | Gap junction (KEGG):04540 |
0.000248948414545059 | 0.0143258496733657 | 6 | 70 | Long-term potentiation (KEGG):04720 |
4.51163032377388e-06 | 0.00095195399831629 | 10 | 126 | Glutamatergic synapse (KEGG):04724 |
0.000540350719019034 | 0.028503500428254 | 7 | 112 | Wnt Signaling Pathway NetPath (Wikipathways):WP363 |
0.000795690400175516 | 0.0387440017931617 | 3 | 15 | GPCRs, Class C Metabotropic glutamate, pheromone (Wikipathways):WP501 |
4.59849542482566e-05 | 0.00363855950489331 | 5 | 32 | Hypothetical Network for Drug Addiction (Wikipathways):WP666 |
8.01823943464713e-06 | 0.00101510911242633 | 12 | 197 | Synaptic Transmission (Reactome):REACT_13685 |
5.4385689802965e-14 | 3.44261416452769e-11 | 24 | 265 | Axon guidance (Reactome):REACT_18266 |
2.33856132254937e-05 | 0.00246718219528959 | 5 | 28 | {DLG4,28} (Static Module):NA |
0.000219863517977324 | 0.0139173606879646 | 3 | 10 | {PAK2,10} (Static Module):NA |
6.8388258594864e-06 | 0.00101510911242633 | 10 | 132 | {RAC1,133} (Static Module):NA |
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0007399 | nervous system development | 0 |
GO:0048731 | system development | 3.42916750319792e-38 |
GO:0048856 | anatomical structure development | 3.66233684922925e-34 |
GO:0007275 | multicellular organismal development | 1.51604183866946e-30 |
GO:0032501 | multicellular organismal process | 3.53092113255232e-25 |
GO:0032502 | developmental process | 6.77432320723079e-25 |
GO:0030182 | neuron differentiation | 3.5557282734419e-16 |
GO:0005856 | cytoskeleton | 9.02523401205732e-16 |
GO:0048699 | generation of neurons | 6.64483131866011e-15 |
GO:0022008 | neurogenesis | 3.450544579738e-14 |
GO:0005515 | protein binding | 3.52779871747566e-14 |
GO:0044464 | cell part | 4.66400648694327e-13 |
GO:0048869 | cellular developmental process | 4.82965222239229e-13 |
GO:0030154 | cell differentiation | 4.82965222239229e-13 |
GO:0016020 | membrane | 6.70703301551283e-13 |
GO:0005886 | plasma membrane | 2.29518497285206e-12 |
GO:0007267 | cell-cell signaling | 2.90829318129329e-12 |
GO:0031175 | neurite development | 6.8168318272438e-12 |
GO:0016043 | cellular component organization and biogenesis | 1.80595350629252e-11 |
GO:0044425 | membrane part | 2.19105363050995e-11 |
GO:0048666 | neuron development | 4.64857080063647e-11 |
GO:0007010 | cytoskeleton organization and biogenesis | 5.27810979863882e-11 |
GO:0009653 | anatomical structure morphogenesis | 7.98231720510016e-11 |
GO:0008092 | cytoskeletal protein binding | 9.0025853354009e-11 |
GO:0000902 | cell morphogenesis | 9.10035609909797e-11 |
GO:0032989 | cellular structure morphogenesis | 9.10035609909797e-11 |
GO:0007154 | cell communication | 8.49180039197281e-10 |
GO:0007268 | synaptic transmission | 9.2065834010474e-10 |
GO:0007409 | axonogenesis | 1.50834744457238e-09 |
GO:0048858 | cell projection morphogenesis | 2.25711452284648e-09 |
GO:0032990 | cell part morphogenesis | 2.25711452284648e-09 |
GO:0030030 | cell projection organization and biogenesis | 2.25711452284648e-09 |
GO:0048667 | neuron morphogenesis during differentiation | 2.47960641877007e-09 |
GO:0048812 | neurite morphogenesis | 2.47960641877007e-09 |
GO:0000904 | cellular morphogenesis during differentiation | 4.47760845004081e-09 |
GO:0019226 | transmission of nerve impulse | 6.53387227446778e-09 |
GO:0031224 | intrinsic to membrane | 8.9114154883612e-09 |
GO:0044459 | plasma membrane part | 1.24743624720511e-08 |
GO:0030054 | cell junction | 1.2796607339596e-08 |
GO:0007417 | central nervous system development | 1.45911773509788e-08 |
GO:0016021 | integral to membrane | 1.45911773509788e-08 |
GO:0005737 | cytoplasm | 6.48839158082037e-08 |
GO:0007420 | brain development | 1.49530239446313e-07 |
GO:0007165 | signal transduction | 2.397293477489e-07 |
GO:0048468 | cell development | 3.91241223927337e-07 |
GO:0050789 | regulation of biological process | 8.58264685933664e-07 |
GO:0031114 | regulation of microtubule depolymerization | 8.71715035020438e-07 |
GO:0007026 | negative regulation of microtubule depolymerization | 8.71715035020438e-07 |
GO:0044424 | intracellular part | 9.8327962522705e-07 |
GO:0030295 | protein kinase activator activity | 1.08054308042338e-06 |
GO:0007019 | microtubule depolymerization | 1.08054308042338e-06 |
GO:0031111 | negative regulation of microtubule polymerization or depolymerization | 1.08054308042338e-06 |
GO:0043005 | neuron projection | 1.16449174378467e-06 |
GO:0065007 | biological regulation | 1.17555022143405e-06 |
GO:0051261 | protein depolymerization | 3.9839689816965e-06 |
GO:0007017 | microtubule-based process | 4.34238409436252e-06 |
GO:0031110 | regulation of microtubule polymerization or depolymerization | 4.43509360761182e-06 |
GO:0044456 | synapse part | 5.41727200793187e-06 |
GO:0031109 | microtubule polymerization or depolymerization | 7.99276122061449e-06 |
GO:0051129 | negative regulation of cellular component organization and biogenesis | 8.72132651833816e-06 |
GO:0050794 | regulation of cellular process | 8.72620938362211e-06 |
GO:0019209 | kinase activator activity | 8.94222759115674e-06 |
GO:0030426 | growth cone | 8.94222759115674e-06 |
GO:0005874 | microtubule | 1.14198782680398e-05 |
GO:0005622 | intracellular | 1.14198782680398e-05 |
GO:0030427 | site of polarized growth | 1.15000456113826e-05 |
GO:0007411 | axon guidance | 1.31339501353869e-05 |
GO:0007242 | intracellular signaling cascade | 1.39609022316097e-05 |
GO:0045211 | postsynaptic membrane | 1.88628029485488e-05 |
GO:0042995 | cell projection | 1.88628029485488e-05 |
GO:0015630 | microtubule cytoskeleton | 2.07344557160584e-05 |
GO:0004157 | dihydropyrimidinase activity | 5.16732416657154e-05 |
GO:0043228 | non-membrane-bound organelle | 6.08075555053569e-05 |
GO:0043232 | intracellular non-membrane-bound organelle | 6.08075555053569e-05 |
GO:0048523 | negative regulation of cellular process | 6.70586829170916e-05 |
GO:0005794 | Golgi apparatus | 6.70586829170916e-05 |
GO:0051248 | negative regulation of protein metabolic process | 7.63700270790536e-05 |
GO:0008021 | synaptic vesicle | 7.63700270790536e-05 |
GO:0019887 | protein kinase regulator activity | 8.00499495895361e-05 |
GO:0043226 | organelle | 8.26553474901764e-05 |
GO:0007163 | establishment and/or maintenance of cell polarity | 8.89723992926584e-05 |
GO:0043229 | intracellular organelle | 0.000140733398828741 |
GO:0006996 | organelle organization and biogenesis | 0.000141440384189975 |
GO:0048519 | negative regulation of biological process | 0.000163086275392608 |
GO:0043025 | cell soma | 0.000221870794344543 |
GO:0019207 | kinase regulator activity | 0.000222937724045669 |
GO:0031226 | intrinsic to plasma membrane | 0.000256283592696472 |
GO:0030159 | receptor signaling complex scaffold activity | 0.000259713722908952 |
GO:0048513 | organ development | 0.00027604822223895 |
GO:0030425 | dendrite | 0.000317005482636633 |
GO:0032947 | protein complex scaffold | 0.000392116652612512 |
GO:0015631 | tubulin binding | 0.000434867215621882 |
GO:0051128 | regulation of cellular component organization and biogenesis | 0.000465643828722441 |
GO:0007215 | glutamate signaling pathway | 0.000465643828722441 |
GO:0009892 | negative regulation of metabolic process | 0.000592315701652324 |
GO:0005887 | integral to plasma membrane | 0.000642634834106947 |
GO:0044430 | cytoskeletal part | 0.000735041808147006 |
GO:0019894 | kinesin binding | 0.00077130632065477 |
GO:0008017 | microtubule binding | 0.00101079337789295 |
GO:0030136 | clathrin-coated vesicle | 0.00106376615285904 |
GO:0045055 | regulated secretory pathway | 0.00144841610062207 |
GO:0044431 | Golgi apparatus part | 0.00148952086116649 |
GO:0000139 | Golgi membrane | 0.0015412146462981 |
GO:0012505 | endomembrane system | 0.00163451632020952 |
GO:0007218 | neuropeptide signaling pathway | 0.00177325011504058 |
GO:0042734 | presynaptic membrane | 0.00183099184926607 |
GO:0003779 | actin binding | 0.00214371155596119 |
GO:0006928 | cell motility | 0.00227375902564883 |
GO:0051674 | localization of cell | 0.00227375902564883 |
GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | 0.00227864865597557 |
GO:0051641 | cellular localization | 0.00251317441237717 |
GO:0005875 | microtubule associated complex | 0.00266508657201481 |
GO:0030424 | axon | 0.00272576136131084 |
GO:0051010 | microtubule plus-end binding | 0.00272576136131084 |
GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity | 0.00272576136131084 |
GO:0005078 | MAP-kinase scaffold activity | 0.00272576136131084 |
GO:0016477 | cell migration | 0.00298121402305956 |
GO:0000226 | microtubule cytoskeleton organization and biogenesis | 0.00352907957177657 |
GO:0030135 | coated vesicle | 0.00408213018131941 |
GO:0003001 | generation of a signal involved in cell-cell signaling | 0.00454661699894548 |
GO:0007269 | neurotransmitter secretion | 0.00483651981731951 |
GO:0051246 | regulation of protein metabolic process | 0.00487381307161995 |
GO:0051649 | establishment of cellular localization | 0.00490493729234046 |
GO:0030971 | receptor tyrosine kinase binding | 0.00502924929939348 |
GO:0005828 | kinetochore microtubule | 0.00502924929939348 |
GO:0022610 | biological adhesion | 0.00539048178996356 |
GO:0007155 | cell adhesion | 0.00539048178996356 |
GO:0019222 | regulation of metabolic process | 0.00566045210233311 |
GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity | 0.00627938142265481 |
GO:0019198 | transmembrane receptor protein phosphatase activity | 0.00627938142265481 |
GO:0001505 | regulation of neurotransmitter levels | 0.00685724278682288 |
GO:0017124 | SH3 domain binding | 0.0072278715921299 |
GO:0030695 | GTPase regulator activity | 0.00766673766676316 |
GO:0018065 | protein-cofactor linkage | 0.0077731373112513 |
GO:0005200 | structural constituent of cytoskeleton | 0.00977442865904356 |
GO:0019904 | protein domain specific binding | 0.00977442865904356 |
GO:0016524 | latrotoxin receptor activity | 0.0106075277809639 |
GO:0030296 | protein tyrosine kinase activator activity | 0.0112552299957482 |
GO:0007018 | microtubule-based movement | 0.0115703401418131 |
GO:0050793 | regulation of developmental process | 0.0126384934951925 |
GO:0009966 | regulation of signal transduction | 0.013237548769626 |
GO:0007264 | small GTPase mediated signal transduction | 0.0136080790256467 |
GO:0045045 | secretory pathway | 0.0137597429228049 |
GO:0008066 | glutamate receptor activity | 0.0144267813414993 |
GO:0050770 | regulation of axonogenesis | 0.0144267813414993 |
GO:0031301 | integral to organelle membrane | 0.0144794849764786 |
GO:0007158 | neuron adhesion | 0.0146063834955669 |
GO:0001578 | microtubule bundle formation | 0.0146063834955669 |
GO:0019899 | enzyme binding | 0.0157987679119271 |
GO:0051258 | protein polymerization | 0.0159461568274189 |
GO:0031982 | vesicle | 0.0161800661997234 |
GO:0008134 | transcription factor binding | 0.0161800661997234 |
GO:0005085 | guanyl-nucleotide exchange factor activity | 0.0168059667178649 |
GO:0030705 | cytoskeleton-dependent intracellular transport | 0.0169836482925688 |
GO:0022836 | gated channel activity | 0.0177901140393509 |
GO:0005881 | cytoplasmic microtubule | 0.018251067615488 |
GO:0003730 | mRNA 3'-UTR binding | 0.018251067615488 |
GO:0031300 | intrinsic to organelle membrane | 0.0208250063540242 |
GO:0046903 | secretion | 0.0208250063540242 |
GO:0002062 | chondrocyte differentiation | 0.0226322752557863 |
GO:0008047 | enzyme activator activity | 0.0226322752557863 |
GO:0019932 | second-messenger-mediated signaling | 0.0239151923102481 |
GO:0044422 | organelle part | 0.0245234818656668 |
GO:0003924 | GTPase activity | 0.0270188420115136 |
GO:0001540 | beta-amyloid binding | 0.0272827096468203 |
GO:0005083 | small GTPase regulator activity | 0.0292386846782992 |
GO:0051056 | regulation of small GTPase mediated signal transduction | 0.0295275304745269 |
GO:0005231 | excitatory extracellular ligand-gated ion channel activity | 0.0309693485069638 |
GO:0001764 | neuron migration | 0.0309693485069638 |
GO:0019717 | synaptosome | 0.0309693485069638 |
GO:0016247 | channel regulator activity | 0.0309693485069638 |
GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | 0.0309693485069638 |
GO:0005246 | calcium channel regulator activity | 0.0316009420462899 |
GO:0031988 | membrane-bound vesicle | 0.0343176994981004 |
GO:0008373 | sialyltransferase activity | 0.0350552337150717 |
GO:0050767 | regulation of neurogenesis | 0.0350552337150717 |
GO:0019935 | cyclic-nucleotide-mediated signaling | 0.0357379919857634 |
GO:0045767 | regulation of anti-apoptosis | 0.0360377507174353 |
GO:0016358 | dendrite development | 0.0360377507174353 |
GO:0030516 | regulation of axon extension | 0.0360377507174353 |
GO:0044446 | intracellular organelle part | 0.0360377507174353 |
GO:0050877 | neurological system process | 0.0360377507174353 |
GO:0031410 | cytoplasmic vesicle | 0.0364945411492439 |
GO:0032940 | secretion by cell | 0.0385177209255228 |
GO:0004860 | protein kinase inhibitor activity | 0.0385836920973071 |
GO:0045761 | regulation of adenylate cyclase activity | 0.0409239831444474 |
GO:0003712 | transcription cofactor activity | 0.0415760387557223 |
GO:0051339 | regulation of lyase activity | 0.0428830180717856 |
GO:0031279 | regulation of cyclase activity | 0.0428830180717856 |
GO:0019210 | kinase inhibitor activity | 0.0428830180717856 |
GO:0003008 | system process | 0.0438511399644669 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
neurectodermal cell | 1.80e-09 | 59 |
neural cell | 2.06e-09 | 25 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.