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Coexpression cluster:C3391: Difference between revisions

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|ontology_enrichment_celltype=
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001049!2.50e-51!57;UBERON:0005068!2.50e-51!57;UBERON:0006241!2.50e-51!57;UBERON:0007135!2.50e-51!57;UBERON:0002780!1.76e-48!41;UBERON:0001890!1.76e-48!41;UBERON:0006240!1.76e-48!41;UBERON:0001017!3.80e-48!82;UBERON:0003080!5.09e-47!42;UBERON:0005743!8.17e-47!86;UBERON:0000073!3.57e-45!94;UBERON:0001016!3.57e-45!94;UBERON:0002616!2.80e-44!59;UBERON:0000955!1.23e-42!69;UBERON:0006238!1.23e-42!69;UBERON:0002020!9.82e-39!34;UBERON:0003528!9.82e-39!34;UBERON:0001893!1.17e-38!34;UBERON:0002346!3.17e-37!90;UBERON:0002791!4.12e-37!33;UBERON:0001869!1.73e-36!32;UBERON:0003075!1.21e-34!86;UBERON:0007284!1.21e-34!86;UBERON:0007023!1.54e-34!115;UBERON:0003056!5.57e-30!61;UBERON:0000956!5.74e-29!25;UBERON:0000203!5.74e-29!25;UBERON:0001950!4.77e-26!20;UBERON:0002619!4.95e-26!22;UBERON:0000924!3.22e-25!173;UBERON:0006601!3.22e-25!173;UBERON:0004121!3.45e-23!169;UBERON:0000033!4.76e-22!123;UBERON:0000153!2.99e-20!129;UBERON:0007811!2.99e-20!129;UBERON:0000025!2.93e-12!194;UBERON:0002420!2.81e-11!9;UBERON:0007245!2.81e-11!9;UBERON:0010009!2.81e-11!9;UBERON:0010011!2.81e-11!9;UBERON:0000454!2.81e-11!9;UBERON:0001894!3.67e-11!7;UBERON:0006222!3.67e-11!7;UBERON:0002308!4.38e-11!9;UBERON:0000125!4.38e-11!9;UBERON:0000200!1.97e-10!6;UBERON:0001871!2.74e-10!7;UBERON:0004111!4.63e-09!241;UBERON:0001872!8.57e-09!5;UBERON:0002298!1.20e-08!8;UBERON:0009663!2.76e-08!7;UBERON:0000369!9.06e-08!4;UBERON:0002435!9.06e-08!4;UBERON:0000204!9.06e-08!4;UBERON:0010082!9.06e-08!4;UBERON:0000477!1.37e-07!286;UBERON:0003296!2.15e-07!4;UBERON:0010133!2.15e-07!4;UBERON:0000483!2.70e-07!309;UBERON:0000119!4.62e-07!312;UBERON:0003076!4.80e-07!15;UBERON:0003057!4.80e-07!15;UBERON:0000475!9.16e-07!365
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475,0.0558058,0.28262,0.517717,0.137332,0.0145999,0.0656973,0.211746,0.220538,0.0801488,0.0757897,0.161801,0.193215,0.0549034,0.0779715,0.0561838,0.0417636,0.0345419,0.0388736,0.254674,0.170307,0.201033,0.0488949,0.174921,0.370421,0.0330727,0.348757,0.219556,0.0394698,0.0596469,0.419264,0.122476,0.108872,0.11002,0.26144,0.0286025,0.549354,0.144567,0.038848,0.0874516,0.0550279,0.144067,0.253693,0.0254773,0.190048,0.00899422,0.394069,0.237101,0.286988,0.0761239,0.172491,0.0818785,0.182701,0.335058,0.147698,0.141463,0.167267,0.140622,0.0889592,0.309588,0.28711,0.0473033,0.094881,0.445524,0.132886,0.0774373,0.109194,0.128564,0.131452,0.687347,0.448776,0.051838,0.0993999,0.0500365,0.061829,0.0755121,0.0936516,0.144075,0.0340203,0.0741807,0.277091,0.389379,0.288159,0.21727,0.289306,0.119215,0.192475,0.177967,0.547859,0.057571,0.047591,0.392974,0.0608699,0.175319,0.300597,0.0713214,0.223874,0.291114,0.0355833,0.125606,0.175094,0.696435,0.76084,0.206454,0.218192,0.108277,0.0673484,0.108748,0.0494066,0.0958493,0.0227848,0.0755808,0.045654,0.110216,0.070276,0.226171,0.0124298,0.0376916,0.13262,0.0450031,0.0539144,0.114242,0.0929549,0.172425,0.104948,0.221645,0.057168,0.234298,0.0759837,0.286863,0.152372,0.194941,0.218271,0.101607,0.060512,0.172982,0.340936,0.151597,0.0626744,0.191335,0.148574,0.15663,0.155821,0.0718905,0.00435853,0.0602373,0.000561466,0.15063,0.0973823,0.15503,0.170295,0.193653,0.137219,0.228144,0.251466,0.288096,0.11903,0.0838874,0.0622625,0.113145,0.112651,0.0186145,0.174776,0.0948451,0.264079,0.249049,0.140533,0.0997756,0.257598,0.103667,0.113069,0.025556,0.0149597,0.09066,0.220462,0.166967,0.188651,0.0813902,0.184948,0.156261,0.311847,0.511859,0.0590944,0.247324,0.178389,0.218229,0.231073,0.407281,0.619906,0.0360851,0.412187,0.131093,0.0434602,0.133616,0.103051,0.36927,0.0227305,0.407369,0.231447,0.18653,0.43956,0.37006,0.42622,0.448797,0.0209277,0.396996,0.36145,0.406019,0.0841307,0.580441,0.276075,0.432035,0.366326,0.390366,0.48809,0.0334527,0.117158,0.522904,0.3468,0.336835,0.227104,0.518585,0.250246,0.38649,0.284625,0.504757,0.55194,0.144318,0.28907,0.164197,0.462688,0.287881,0.21103,0.138768,0.0642229,0.468444,0.258219,0.446557,0.032364,0.191695,0.0889613,0.149257,0.683217,0.161598,0.405056,0.644754,0.150692,0.799185,0.0120582,0.454657,0.477353,0.452741,0.746954,0.43491,0.20342,0.200493,0.20558,0.300504,0.0361545,0.107337,0.349197,0.383291,0.156104,0.141318,0.411941,0.0961477,0.055627,0.354789,0.163828,0.230581,0.120226,0.28424,0.20075,0.314429,0.181415,0.282286,0.194707,0.616388,0.408413,0.516511,0.322213,0.656109,0.33942,0.243065,0.387276,0.169614,0.802166,0.537348,0.222037,0.416621,0.416292,0.462712,0.0457685,0.579431,0.204817,0.00340294,0.138871,0.308032,0.166905,0.19783,0.0833851,0.316453,0.48065,0.175199,0.332919,0.373557,0.523625,0.408861,0.365487,0.178743,0.39088,0.363192,0.236011,0.203486,0.273398,0.375787,0.4466,0.351067,0.275347,0.269604,0.0524515,0.000193887,0.371414,0.30666,0.303709,0.495883,0.386538,0.508064,0.0345164,0.383276,0.457886,0.00582796,0.0262575,0.509064,0.196976,0.191517,0.463751,0.601877,0.307334,0.000443066,0.283463,0.201728,0.472935,0.399569,0.0413011,0.368095,0.0418805,0.0858306,0.0283414,0.359231,0.339729,0.197805,0.0690807,0.387069,0.332774,0.52832,0.299887,0.634365,0.205413,0.17639,0.0779009,0.276869,0.205298,0.0337138,0.18966,0.258854,0.0189519,0.0719199,0.264884,0.162568,0.19104,0.163057,0.00210664,0.208013,0.0900729,0.0953646,0.166124,0.00329437,0.378361,0.255516,0.20753,0.119514,0.179412,0.193601,0.220904,0.222977,0.341681,0.310674,0.0257082,0.198614,0.186804,0.123324,0.199468,0.0325925,0.0933115,0.12405,0.179889,0.226869,0.27872,0.0855609,0.131118,0.20837,0.247588,0.0267847,0.0673329,0.20847,0.0391817,0.113092,0.0111711,0.0285999,0.162145,0.228955,0.168748,0.0384949,0.0660995,0.0521984,0.0455518,0.268741,0.201602,0.350452,0.154941,0.120196,0.0986735,0.108462,0.0595618,0.21593,0.158479,0.220319,0.195218,0.124213,0.259632,0.30793,0.180606,0.159884,0.257294,0.150733,0.217112,0.123917,0.184317,0.185335,0.0723291,0.258496,0.261744,0.203781,0.21382,0.0232077,0.141867,0.193031,0.249101,0.115972,0.224568,0.246105,0.173026,0.200432,0.139785,0.197112,0.240478,0.156465,0.13108,0.256963,0.222798,0.172134,0.0166394,0.0969345,0.202137,0.310405,0.280943,0.218161,0.0822373,0.202065,0.106739,0.0536053,0.0537737,0.15113,0.078016,0.0407233,0.0537355,0.319922,0.261724,0.211332,0.187731,0.233626,0.189559,0.0812887,0.0981146,0.064145,0.121913,0.0638699,0.104603,0.0663259,0.0762523,0.128736,0.109171,0.04411,0.066952,0.089609,0.0367455,0.13497,0.204393,0.295769,0.286691,0.0687209,0.141729,0.263159,0.255956,0.0215087,0.227491,0.29837,0.253509,0.177664,0.28365,0.00384051,0.000422974,0.160658,0.206239,0.19924,0.28689,0.236464,0.325148,0.115817,0.218052,0.223831,0.11528,0.194982,0.190993,0.0440463,0.283218,0.249955,0.164638,0.0272695,0.0935776,0.327622,0.225752,0.207791,0.0958756,0.0859274,0.316866,0.171683,0.158847,0.271275,0.071111,0.270604,0.101021,0.222548,0.0164735,0.157274,0.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}}
}}

Revision as of 15:03, 19 October 2012


Full id: C3391_amygdala_brain_parietal_occipital_insula_putamen_middle



Phase1 CAGE Peaks

Hg19::chr13:99668217..99668224,-p23@DOCK9
Hg19::chr14:51562005..51562012,-p5@TRIM9
Hg19::chr7:140984977..140984981,+p@chr7:140984977..140984981
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube1.21e-8656
neural rod1.21e-8656
future spinal cord1.21e-8656
neural keel1.21e-8656
regional part of nervous system1.60e-8653
regional part of brain1.60e-8653
regional part of forebrain3.35e-8241
forebrain3.35e-8241
anterior neural tube3.35e-8241
future forebrain3.35e-8241
telencephalon8.67e-7434
brain grey matter1.05e-7334
gray matter1.05e-7334
brain1.68e-7368
future brain1.68e-7368
cerebral hemisphere1.68e-7232
central nervous system4.11e-7281
regional part of telencephalon3.08e-6632
nervous system3.00e-6489
neural plate1.71e-6082
presumptive neural plate1.71e-6082
neurectoderm2.40e-5786
pre-chordal neural plate2.91e-5761
regional part of cerebral cortex1.73e-5222
cerebral cortex1.28e-5125
pallium1.28e-5125
neocortex5.49e-5120
ecto-epithelium3.82e-46104
structure with developmental contribution from neural crest4.51e-37132
adult organism1.62e-36114
ectoderm-derived structure7.63e-32171
ectoderm7.63e-32171
presumptive ectoderm7.63e-32171
organ system subdivision5.71e-24223
basal ganglion1.20e-239
nuclear complex of neuraxis1.20e-239
aggregate regional part of brain1.20e-239
collection of basal ganglia1.20e-239
cerebral subcortex1.20e-239
neural nucleus3.78e-239
nucleus of brain3.78e-239
temporal lobe4.00e-226
tube1.77e-21192
corpus striatum1.82e-184
striatum1.82e-184
ventral part of telencephalon1.82e-184
future corpus striatum1.82e-184
gyrus2.83e-186
brainstem4.46e-176
telencephalic nucleus8.93e-167
anatomical conduit1.33e-15240
limbic system5.42e-155
occipital lobe1.50e-145
caudate-putamen2.77e-143
dorsal striatum2.77e-143
pons3.59e-133
anatomical cluster1.07e-12373
organ part4.26e-12218
epithelium2.17e-11306
cell layer3.35e-11309
gland of diencephalon1.63e-104
neuroendocrine gland1.63e-104
amygdala3.03e-102
caudate nucleus3.79e-102
future caudate nucleus3.79e-102
multi-tissue structure4.12e-10342
diencephalon4.90e-107
future diencephalon4.90e-107
pituitary gland8.08e-102
locus ceruleus1.36e-092
brainstem nucleus1.36e-092
hindbrain nucleus1.36e-092
posterior neural tube2.06e-0915
chordal neural plate2.06e-0915
middle temporal gyrus2.29e-092
parietal lobe6.84e-095
segmental subdivision of hindbrain2.00e-0812
hindbrain2.00e-0812
presumptive hindbrain2.00e-0812
segmental subdivision of nervous system9.33e-0813
frontal cortex5.03e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.