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Coexpression cluster:C3419

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Full id: C3419_cerebellum_colon_medial_parietal_middle_occipital_testis



Phase1 CAGE Peaks

Hg19::chr14:27067411..27067418,-p13@NOVA1
Hg19::chr14:27067428..27067485,-p2@NOVA1
Hg19::chr14:27067502..27067512,-p@chr14:27067502..27067512
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.47e-3694
nervous system1.47e-3694
neural plate1.08e-3586
presumptive neural plate1.08e-3586
central nervous system3.25e-3582
neurectoderm9.15e-3590
neural tube1.10e-3457
neural rod1.10e-3457
future spinal cord1.10e-3457
neural keel1.10e-3457
regional part of brain1.43e-3159
cell layer8.15e-31312
epithelium2.08e-30309
brain7.97e-3069
future brain7.97e-3069
adult organism2.03e-28115
organism subdivision4.00e-27365
pre-chordal neural plate2.32e-2661
ectoderm-derived structure4.94e-26169
head5.74e-26123
ectoderm7.13e-26173
presumptive ectoderm7.13e-26173
anterior neural tube1.90e-2542
anterior region of body4.35e-25129
craniocervical region4.35e-25129
regional part of forebrain7.24e-2541
forebrain7.24e-2541
future forebrain7.24e-2541
tube9.36e-24194
multi-tissue structure2.73e-23347
anatomical conduit1.18e-22241
gray matter5.75e-2234
brain grey matter5.75e-2234
telencephalon6.94e-2234
anatomical cluster1.11e-21286
regional part of telencephalon3.22e-2133
cerebral hemisphere1.54e-2032
cerebral cortex4.65e-1625
pallium4.65e-1625
regional part of cerebral cortex8.91e-1622
multi-cellular organism9.61e-16659
embryo3.17e-15612
neocortex1.58e-1420
embryonic structure2.62e-13605
developing anatomical structure2.62e-13605
anatomical system5.04e-13625
germ layer5.98e-13604
embryonic tissue5.98e-13604
presumptive structure5.98e-13604
epiblast (generic)5.98e-13604
anatomical group8.46e-13626
organ part6.67e-11219
posterior neural tube3.02e-1015
chordal neural plate3.02e-1015
segmental subdivision of nervous system5.83e-0913
segmental subdivision of hindbrain2.48e-0812
hindbrain2.48e-0812
presumptive hindbrain2.48e-0812
nucleus of brain2.21e-079
neural nucleus2.21e-079
organ2.85e-07511
basal ganglion3.16e-079
nuclear complex of neuraxis3.16e-079
aggregate regional part of brain3.16e-079
collection of basal ganglia3.16e-079
cerebral subcortex3.16e-079
brainstem8.73e-078


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.