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MCL coexpression mm9:189

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:111706834..111706844,+p@chr10:111706834..111706844
+
Mm9::chr10:111706991..111707011,+p@chr10:111706991..111707011
+
Mm9::chr10:111707065..111707085,+p@chr10:111707065..111707085
+
Mm9::chr10:6473722..6473734,-p@chr10:6473722..6473734
-
Mm9::chr10:6473752..6473760,-p@chr10:6473752..6473760
-
Mm9::chr10:6482674..6482689,-p@chr10:6482674..6482689
-
Mm9::chr10:6482698..6482722,-p@chr10:6482698..6482722
-
Mm9::chr10:6482729..6482747,-p@chr10:6482729..6482747
-
Mm9::chr10:6482834..6482851,-p@chr10:6482834..6482851
-
Mm9::chr12:88331519..88331538,-p@chr12:88331519..88331538
-
Mm9::chr14:31438329..31438344,-p@chr14:31438329..31438344
-
Mm9::chr14:31439596..31439613,-p3@Prkcd
Mm9::chr14:66893581..66893589,-p@chr14:66893581..66893589
-
Mm9::chr15:74393929..74393977,+p3@Bai1
Mm9::chr15:89330500..89330539,+p3@Shank3
Mm9::chr15:89330547..89330576,+p4@Shank3
Mm9::chr16:89818436..89818447,-p19@Tiam1
Mm9::chr16:89818560..89818572,-p17@Tiam1
Mm9::chr16:89818583..89818601,-p11@Tiam1
Mm9::chr16:89818603..89818642,-p10@Tiam1
Mm9::chr17:37190662..37190667,+p@chr17:37190662..37190667
+
Mm9::chr1:121733665..121733716,-p3@Ptpn4
Mm9::chr1:155500073..155500084,+p7@Rgs8
Mm9::chr2:180773865..180773897,-p4@Chrna4
Mm9::chr2:90725607..90725616,+p11@C1qtnf4
Mm9::chr2:90725632..90725658,+p5@C1qtnf4
Mm9::chr2:90725660..90725680,+p2@C1qtnf4
Mm9::chr2:90725684..90725718,+p3@C1qtnf4
Mm9::chr3:109945662..109945676,-p@chr3:109945662..109945676
-
Mm9::chr3:109946480..109946497,-p6@Ntng1
Mm9::chr4:11892818..11892825,-p4@Pdp1
Mm9::chr4:11892846..11892899,-p2@Pdp1
Mm9::chr4:120527452..120527472,+p2@Rims3
Mm9::chr4:57253865..57253876,-p@chr4:57253865..57253876
-
Mm9::chr4:57253877..57253880,-p@chr4:57253877..57253880
-
Mm9::chr4:57253914..57253928,-p@chr4:57253914..57253928
-
Mm9::chr4:57253994..57254011,-p@chr4:57253994..57254011
-
Mm9::chr4:57254051..57254064,-p@chr4:57254051..57254064
-
Mm9::chr4:57254065..57254072,-p@chr4:57254065..57254072
-
Mm9::chr4:57447275..57447280,+p21@Palm2
Mm9::chr5:116357544..116357559,+p5@Cit
Mm9::chr5:144125569..144125598,+p1@Grid2ip
Mm9::chr5:49916315..49916324,-p12@Kcnip4
Mm9::chr6:119280824..119280835,-p6@Lrtm2
Mm9::chr6:48398099..48398121,+p2@LOC100505089
p2@Sspo
Mm9::chr6:77194015..77194026,+p@chr6:77194015..77194026
+
Mm9::chr6:97010401..97010414,-p1@Fam19a4
Mm9::chr7:147019990..147020001,+p8@Gpr123
Mm9::chr7:54388765..54388783,-p12@Ptpn5
Mm9::chr9:14438679..14438684,-p@chr9:14438679..14438684
-
Mm9::chr9:14438716..14438721,-p@chr9:14438716..14438721
-
Mm9::chr9:14438735..14438768,-p@chr9:14438735..14438768
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007242intracellular signaling cascade0.0220019448240821
GO:0000910cytokinesis0.0220019448240821
GO:0008289lipid binding0.0220019448240821
GO:0009653anatomical structure morphogenesis0.0220019448240821
GO:0048667neuron morphogenesis during differentiation0.0220019448240821
GO:0048812neurite morphogenesis0.0220019448240821
GO:0000904cellular morphogenesis during differentiation0.0220019448240821
GO:0031175neurite development0.0220019448240821
GO:0050767regulation of neurogenesis0.0220019448240821
GO:0019992diacylglycerol binding0.0220019448240821
GO:0032989cellular structure morphogenesis0.0220019448240821
GO:0000902cell morphogenesis0.0220019448240821
GO:0004871signal transducer activity0.0220019448240821
GO:0060089molecular transducer activity0.0220019448240821
GO:0048666neuron development0.0255410999797033
GO:0050793regulation of developmental process0.0360345855340333
GO:0032990cell part morphogenesis0.0360345855340333
GO:0048858cell projection morphogenesis0.0360345855340333
GO:0030030cell projection organization and biogenesis0.0360345855340333
GO:0030182neuron differentiation0.0362637128350096
GO:0030695GTPase regulator activity0.0362637128350096
GO:0046875ephrin receptor binding0.0362637128350096
GO:0050774negative regulation of dendrite morphogenesis0.0362637128350096
GO:0060081membrane hyperpolarization0.0362637128350096
GO:0016527brain-specific angiogenesis inhibitor activity0.0362637128350096
GO:0060080regulation of inhibitory postsynaptic membrane potential0.0362637128350096
GO:0042113B cell activation0.0364165181700335
GO:0004725protein tyrosine phosphatase activity0.0364165181700335
GO:0048699generation of neurons0.0376790178359254
GO:0007216metabotropic glutamate receptor signaling pathway0.0376790178359254
GO:0048013ephrin receptor signaling pathway0.0376790178359254
GO:0004726non-membrane spanning protein tyrosine phosphatase activity0.0376790178359254
GO:0022008neurogenesis0.0376790178359254
GO:0016043cellular component organization and biogenesis0.0376790178359254
GO:0006470protein amino acid dephosphorylation0.0376790178359254
GO:0035095behavioral response to nicotine0.0376790178359254
GO:0014059regulation of dopamine secretion0.0376790178359254
GO:0032613interleukin-10 production0.0376790178359254
GO:0014046dopamine secretion0.0376790178359254
GO:0050773regulation of dendrite development0.0376790178359254
GO:0048814regulation of dendrite morphogenesis0.0376790178359254
GO:0007154cell communication0.0376790178359254
GO:0045211postsynaptic membrane0.0376790178359254
GO:0050433regulation of catecholamine secretion0.0410914206991931
GO:0030054cell junction0.0410914206991931
GO:0016311dephosphorylation0.0410914206991931
GO:0044456synapse part0.0411791898620266
GO:0006793phosphorus metabolic process0.0411791898620266
GO:0006796phosphate metabolic process0.0411791898620266
GO:0035094response to nicotine0.0430569600830539
GO:0050432catecholamine secretion0.0430569600830539
GO:0048856anatomical structure development0.0464525514350064
GO:0007091mitotic metaphase/anaphase transition0.0464525514350064
GO:0004727prenylated protein tyrosine phosphatase activity0.0464525514350064



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)2.98e-1123
neuroblast (sensu Vertebrata)2.98e-1123
neuron9.33e-0733
neuronal stem cell9.33e-0733
neuroblast9.33e-0733
electrically signaling cell9.33e-0733

Uber Anatomy
Ontology termp-valuen
regional part of nervous system6.37e-2754
neurectoderm1.21e-2664
neural plate1.21e-2664
presumptive neural plate1.21e-2664
neural tube5.99e-2452
neural rod5.99e-2452
future spinal cord5.99e-2452
neural keel5.99e-2452
ecto-epithelium4.51e-2273
central nervous system7.69e-2273
ectoderm-derived structure3.11e-2195
ectoderm3.11e-2195
presumptive ectoderm3.11e-2195
nervous system5.54e-2175
gray matter2.44e-2034
brain3.85e-1847
future brain3.85e-1847
pre-chordal neural plate1.13e-1749
regional part of brain6.05e-1746
structure with developmental contribution from neural crest2.13e-1592
brain grey matter2.07e-1429
regional part of telencephalon2.07e-1429
telencephalon2.07e-1429
anterior neural tube1.25e-1340
occipital lobe1.63e-1210
visual cortex1.63e-1210
neocortex1.63e-1210
regional part of forebrain1.82e-1239
forebrain1.82e-1239
future forebrain1.82e-1239
posterior neural tube3.23e-1212
chordal neural plate3.23e-1212
spinal cord1.14e-096
dorsal region element1.14e-096
dorsum1.14e-096
regional part of cerebral cortex1.25e-0917
cerebral cortex6.56e-0921
cerebral hemisphere6.56e-0921
pallium6.56e-0921
regional part of spinal cord4.17e-085
gray matter of spinal cord4.17e-085
regional part of midbrain2.17e-074
midbrain2.17e-074
presumptive midbrain2.17e-074
midbrain neural tube2.17e-074
basal ganglion4.08e-078
nuclear complex of neuraxis4.08e-078
aggregate regional part of brain4.08e-078
collection of basal ganglia4.08e-078
cerebral subcortex4.08e-078


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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